UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C25A11.2	C25A11.2	0	chrX 9,115,559	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
2	F32B6.3	F32B6.3	n/a	chrIV 9,883,182	contains similarity to Pfam domains PF02840 (Prp18 domain) , PF08799 (pre-mRNA processing factor 4 (PRP4) like) contains similarity to Interpro domains IPR014906 (Pre-mRNA processing factor 4 (PRP4) like), IPR003648 (Splicing factor motif), IPR004098 (Prp18)
3	F54B8.1	F54B8.1	n/a	chrV 15,811,031	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	C07A4.1	C07A4.1	n/a	chrX 10,169,900	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
6	F55A3.2	F55A3.2	n/a	chrI 10,795,710	contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR015880 (Zinc finger, C2H2-like)
7	F52C9.7	F52C9.7	n/a	chrIII 5,309,798	contains similarity to Interpro domain IPR002226 (Catalase)
8	K08F4.1	K08F4.1	n/a	chrIV 10,124,631	contains similarity to Pfam domain PF00004 ATPase family associated with various cellular activities (AAA) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR001199 (Cytochrome b5), IPR003593 (AAA+ ATPase, core)
9	K10E9.1	K10E9.1	n/a	chrI 196,071
10	srj-4	C27A7.7	n/a	chrV 12,163,847	C. elegans SRJ-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	C27A12.9	C27A12.9	n/a	chrI 6,064,908	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017850 (Alkaline-phosphatase-like, core domain)
12	dyrb-1	T24H10.6	n/a	chrII 9,106,748	dyrb-1 encodes a small (95-residue) putative cytoplasmic dynein light chain 2A that inhibits DHC-1 in vivo, and is also required for mitotic spindle positioning, embryonic viability and fertility; DYRB-1 is orthologous to Drosophila ROADBLOCK (and six Drosophila paralogs), Chlamydomonas LC7, human DYNLRB1 (OMIM:607167), and human DYNLRB2 (OMIM:607168); dyrb-1(RNAi) and dyrb-1(tm2645) both suppress the lethality of conditional dhc-1 mutations, and dyrb-1(RNAi) suppresses dhc-1(or195) spindle length and cytokinesis defects as well, indicating that DYRB-1 negatively regulates dynein; in oocytes and early embryos, DYRB-1 is associated with nuclear envelopes and centrosomes, and with meiotic and mitotic spindle poles; like DHC-1 itself, DYRB-1 is strongly mislocalized to centrosomes in dhc-1(or195) animals shifted to nonpermissive temperature.
13	sec-3	F52E4.7	n/a	chrX 3,097,634	C. elegans SEC-3 protein ; contains similarity to Danio rerio Exocyst complex component 1.; TR:Q7T2A6
14	K07C5.3	K07C5.3	n/a	chrV 10,344,230	contains similarity to Pfam domain PF00645 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region contains similarity to Interpro domain IPR001510 (Zinc finger, PARP-type)
15	ucp-4	K07B1.3	n/a	chrV 9,335,690	C. elegans UCP-4 protein; contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
16	F08F1.9	F08F1.9	n/a	chrX 8,410,171	contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal)
17	cpf-1	F28C6.3	n/a	chrII 8,601,385	C. elegans CPF-1 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR001632 (G-protein, beta subunit), IPR015943 (WD40/YVTN repeat-like)
18	T03G11.6	T03G11.6	n/a	chrX 5,178,330	contains similarity to Pfam domains PF05219 (DREV methyltransferase) , PF08242 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR007884 (DREV methyltransferase)
19	F31E3.4	F31E3.4	n/a	chrIII 6,965,804	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR011046 (WD40 repeat-like), IPR006055 (Exonuclease), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
20	cir-1	F55F8.4	n/a	chrI 5,654,871	C. elegans CIR-1 protein ; contains similarity to Homo sapiens Isoform 1 of CBF1-interacting corepressor; ENSEMBL:ENSP00000339723
21	F20H11.1	F20H11.1	n/a	chrIII 6,590,715	contains similarity to Pfam domain PF00130 Phorbol esters/diacylglycerol binding domain (C1 domain) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
22	B0511.2	B0511.2	n/a	chrI 10,651,985	contains similarity to Interpro domain IPR015804 (Cysteinyl-tRNA synthetase, class Ia, C-terminal)
23	C41H7.3	C41H7.3	n/a	chrII 3,006,666	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
24	K08F11.2	K08F11.2	n/a	chrIV 4,718,190	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
25	Y47H9C.8	Y47H9C.8	n/a	chrI 11,895,073	contains similarity to Streptococcus pneumoniae Magnesium transporter, CorA family.; TR:Q97SX8
26	C14B1.8	C14B1.8	n/a	chrIII 3,719,182	C14B1.8 encodes a coiled-coil protein.
27	C06H2.3	C06H2.3	n/a	chrV 11,128,767	contains similarity to Pfam domains PF02373 (JmjC domain) , PF00583 (Acetyltransferase (GNAT) family) contains similarity to Interpro domains IPR013129 (Transcription factor jumonji), IPR003347 (Transcription factor jumonji/aspartyl beta-hydroxylase), IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase)
28	str-223	F49C5.6	n/a	chrII 12,564,977	C. elegans STR-223 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	apm-3	F53H8.1	n/a	chrX 956,347	apm-3 encodes an adaptin, orthologous to the mu3 subunit of adaptor protein complex 3 (AP-3); APM-3 is also orthologous to human HPS, which when mutated leads to Hermansky-Pudlak syndrome (OMIM:203300); based on structural similarity, APM-3 is predicted to be involved in the formation of intracellular transport vesicles, and genetic analyses indicate that apm-3 activity is required for biogenesis of lysosome-related gut granules.
30	prp-17	F49D11.1	n/a	chrI 10,938,676	C. elegans PRP-17 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
31	H28G03.4	H28G03.4	n/a	chrX 5,223,420	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
32	ZK1098.2	ZK1098.2	n/a	chrIII 9,530,428	contains similarity to Klebsiella aerogenes Siroheme synthetase.; TR:Q9EYX8
33	arx-7	M01B12.3	n/a	chrI 3,069,767	arx-7 encodes the C. elegans ortholog of the p16Arc subunit of the actin-related protein (Arp)2/3 complex.
34	efl-1	Y102A5C.18	n/a	chrV 16,962,099	efl-1 encodes a homolog of mammalian E2F that is required for embryonic asymmetry and that functions as a transcriptional repressor; during vulval development, efl-1, a class B synMuv gene, acts with class B synMuv genes dpl-1 and lin-35/Rb to antagonize receptor tyrosine kinase and Ras-mediated signaling; EFL-1 also negatively regulates the G1 to S phase cell cycle transition.
35	fem-2	T19C3.8	n/a	chrIII 633,323	A CB5161 ortholog of fem-2, Cbn-fem-2, has been isolated from the sibling Caenorhabditis species CB5161.
36	F23C8.9	F23C8.9	n/a	chrI 2,433,103	contains similarity to Pfam domain PF07962 Replication Fork Protection Component Swi3 contains similarity to Interpro domain IPR012923 (Replication fork protection component Swi3)
37	F43G9.10	F43G9.10	n/a	chrI 8,639,367	contains similarity to Pfam domain PF06991 Micro-fibrillar-associated protein 1 C-terminus contains similarity to Interpro domains IPR009730 (Micro-fibrillar-associated 1, C-terminal), IPR000533 (Tropomyosin)
38	bag-1	F57B10.11	n/a	chrI 6,564,081	A homolog of the human BAG-family of co-chaperone proteins, negatively regulates Hsp70 and affects cell stress and cell growth.
39	hsr-9	T05F1.6	n/a	chrI 9,628,707	hsr-9 encodes a protein containing a BRCT (BRCA 1 C terminus) domain that is found in proteins that regulate the cell cycle checkpoint in response to DNA damage; HSR-9 activity is required for a normal response to DNA damage caused by gamma-irradiation; loss of HSR-9 function via RNA-mediated interference after gamma-irradiation results in defects in mitotic cell cycle arrest, reduction of apoptosis of pachytene nuclei, and radiation sensitivity of progeny; the expression pattern and subcellular localization of HSR-9 are not yet known.
40	C23H3.5	C23H3.5	n/a	chrII 48,839
41	hda-2	C08B11.2	n/a	chrII 8,021,602	hda-2 encodes a Class I histone deacetylase; by homology, HDA-2 is predicted to function in deacetylation of histone residues and transcriptional regulation; loss of hda-2 activity via RNAi results in an increased spontaneous mutation rate, suggesting that hda-2 also plays a role in regulating genome stability.
42	cua-1	Y76A2A.2	n/a	chrIII 13,447,397	The cua-1 gene encodes a putative E1-E2 ATPase orthologous to the human gene KIAA1347 (ATP7A; OMIM:604384), which when mutated leads to Hailey-Hailey disease.
43	B0001.5	B0001.5	n/a	chrIV 12,142,216	contains similarity to Saccharomyces cerevisiae Gtpase-activating protein activity toward the essential bud-site assembly GTPase Cdc42; SGD:YPL115C
44	F59H6.3	F59H6.3	n/a	chrII 2,018,441
45	T12G3.5	T12G3.5	n/a	chrIV 12,031,705	contains similarity to Drosophila melanogaster Flybase gene name is mRpL51-PA;; FLYBASE:CG13098
46	T24C4.7	T24C4.7	n/a	chrIII 893,471	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold), IPR007087 (Zinc finger, C2H2-type)
47	srbc-67	T24A6.10	n/a	chrV 3,539,627	C. elegans SRBC-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
48	eri-3	W09B6.3	n/a	chrII 1,125,668	C. elegans ERI-3 protein ;
49	spr-5	Y40B1B.6	n/a	chrI 13,443,987	spr-5 encodes the C. elegans ortholog of the human histone demethylase LSD1 (lysine-specific demethylase 1) that functions to mediate chromatin remodeling and transcriptional regulation; loss of spr-5 activity can suppress the egg-laying defective (Egl) phenotype of mutations in sel-12/presenilin and derepresses expression of hop-1, which encodes the second C. elegans presenilin, by 20- to 30-fold; in binding assays and yeast two-hybrid experiments, SPR-5 interacts with SPR-1, the C. elegans ortholog of CoREST.
50	C08H9.12	C08H9.12	n/a	chrII 9,856,818	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)