UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C18H2.4	C18H2.4	0	chrIII 7,697,463	C18H2.4 is orthologous to the human gene GLOMULIN (FAP48; OMIM:601749), which when mutated leads to disease.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	M03E7.3	M03E7.3	n/a	chrV 5,615,596
4	T27A8.4	T27A8.4	n/a	chrX 16,067,184	contains similarity to Saccharomyces cerevisiae Involved in protein transport at multiple stages of the secretory pathway; SGD:YDR170C
5	F18A12.4	F18A12.4	n/a	chrII 3,405,348	F18A12.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.4 has no clear orthologs in other organisms.
6	H05L14.1	H05L14.1	n/a	chrI 7,974,757	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
7	K10D6.3	K10D6.3	n/a	chrV 11,201,218	contains similarity to Homo sapiens HMG-BOX transcription factor BBX; ENSEMBL:ENSP00000319742
8	tag-344	B0511.4	n/a	chrI 10,644,917	C. elegans TAG-344 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core)
9	F22B5.5	F22B5.5	n/a	chrII 8,453,880	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
10	skr-20	R12H7.5	n/a	chrX 13,223,155	The skr-20 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-20(RNAi) animals are at least superficially normal.
11	R04B5.1	R04B5.1	n/a	chrV 10,078,069	contains similarity to Culex nigripalpus baculovirus Putative 33 kDa early protein (CUN014 similar to AcMNPV ORF92).; TR:Q99GP2
12	F54F12.1	F54F12.1	n/a	chrIII 13,051,731	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
13	F59A3.7	F59A3.7	n/a	chrI 5,517,931
14	C06G4.4	C06G4.4	n/a	chrIII 7,977,442
15	rmd-5	T23B3.3	n/a	chrI 6,711,598	C. elegans RMD-5 protein ; contains similarity to Xenopus laevis Protein FAM82C.; SW:Q5EAU9
16	C17G10.3	C17G10.3	n/a	chrII 5,583,865
17	F18A12.6	F18A12.6	n/a	chrII 3,401,335	F18A12.6 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.6 has no clear orthologs in other organisms.
18	F35E8.6	F35E8.6	n/a	chrV 15,912,576	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR003582 (Metridin-like ShK toxin)
19	R155.3	R155.3	n/a	chrIII 1,973,361	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
20	sru-35	C33D9.4	n/a	chrIV 8,789,328	C. elegans SRU-35 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
21	B0207.1	B0207.1	n/a	chrI 5,966,138	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR000387 (Protein-tyrosine phosphatase), IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000005 (Helix-turn-helix, AraC type), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
22	twk-1	F21C3.1	n/a	chrI 7,270,700	C. elegans TWK-1 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
23	lgc-51	F12B6.3	n/a	chrI 2,244,756	C. elegans LGC-51 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002289 (Gamma-aminobutyric-acid A receptor, beta subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
24	Y51A2D.1	Y51A2D.1	n/a	chrV 18,510,717	contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
25	F26H9.8	F26H9.8	n/a	chrI 9,322,465	contains similarity to Pfam domains PF01501 (Glycosyl transferase family 8) , PF06427 (UDP-glucose:Glycoprotein Glucosyltransferase) contains similarity to Interpro domains IPR000886 (Endoplasmic reticulum, targeting sequence), IPR009448 (UDP-glucose:Glycoprotein Glucosyltransferase), IPR002495 (Glycosyl transferase, family 8)
26	F59A6.3	F59A6.3	n/a	chrII 5,009,745	contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
27	T03F6.4	T03F6.4	n/a	chrIII 13,387,131	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
28	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
29	Y43F8C.9	Y43F8C.9	n/a	chrV 19,646,679	contains similarity to Dictyostelium discoideum Myb-like protein.; SW:P34127
30	F56F3.3	F56F3.3	n/a	chrIII 4,458,938	contains similarity to Drosophila dasycnemia Wingless (Fragment).; TR:O46305
31	dsl-5	F58B3.8	n/a	chrIV 11,620,190	dsl-5 encodes a putative secreted protein with single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-5 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
32	srz-1	F14F8.3	n/a	chrV 16,676,674	srz-1 encodes a predicted seven-pass G protein-coupled receptor; as loss of srz-1 activity via large-scale RNAi screens results in no obvious abnormalities, the precise role of SRZ-1 in C. elegans development and/or behavior is not yet known.
33	srbc-12	K09C6.4	n/a	chrV 850,574	C. elegans SRBC-12 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR003492 (Batten's disease protein Cln3)
34	C28F5.1	C28F5.1	n/a	chrII 7,506,343
35	F59B2.5	F59B2.5	n/a	chrIII 9,001,107	contains similarity to Pfam domain PF01399 PCI domain contains similarity to Interpro domains IPR013143 (PCI/PINT associated module), IPR011991 (Winged helix repressor DNA-binding), IPR000717 (Proteasome component region PCI)
36	C45G9.8	C45G9.8	n/a	chrIII 5,052,953
37	grd-8	C37C3.4	n/a	chrV 7,843,402	grd-8 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-8 is expressed in larval intestine and neurons; the grd-8 gene is directly bound by DAF-12 and requires DAF-12 for full transcription; GRD-8's Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-8 is weakly required for normal molting; GRD-8 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
38	ZK666.2	ZK666.2	n/a	chrII 10,471,714	contains similarity to Homo sapiens ASH1; ENSEMBL:ENSP00000265206
39	F14E5.3	F14E5.3	n/a	chrII 8,436,197	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
40	W04A4.2	W04A4.2	n/a	chrI 13,683,368	contains similarity to Homo sapiens Hypothetical protein FLJ90033; TR:Q8N2R3
41	F28H1.5	F28H1.5	n/a	chrI 3,979,010
42	Y116A8C.19	Y116A8C.19	n/a	chrIV 17,039,245	Y116A8C.19 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y116A8C.19 is predicted to function as an RNA-binding protein.
43	ZK1086.3	ZK1086.3	n/a	chrX 13,791,278	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
44	F40G9.5	F40G9.5	n/a	chrIII 184,128
45	T21E3.2	T21E3.2	n/a	chrI 3,931,189	contains similarity to Homo sapiens 55 kDa protein; ENSEMBL:ENSP00000273725
46	T28D6.3	T28D6.3	n/a	chrIII 11,367,475	contains similarity to Arabidopsis thaliana Hypothetical protein LCR14 precursor.; TR:P82729
47	srv-12	T04B2.4	n/a	chrIV 10,052,440	C. elegans SRV-12 protein ;
48	rnh-1.1	ZK1290.6	n/a	chrII 7,526,915	C. elegans RNH-1.1 protein; contains similarity to Pfam domain PF00075 RNase H contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold), IPR002156 (Ribonuclease H)
49	F46F5.10	F46F5.10	n/a	chrII 824,543	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
50	K02D10.2	K02D10.2	n/a	chrIII 8,770,897