UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C17F4.5	C17F4.5	0	chrII 3,247,215	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
2	C29A12.1	C29A12.1	n/a	chrV 10,812,876	contains similarity to Mesocricetus auratus Synaptonemal complex protein 1 (SCP-1 protein) (Meiotic chromosomessynaptic protein) (Fragment).; SW:SCP1_MESAU
3	C08F8.3	C08F8.3	n/a	chrIV 11,155,803	contains similarity to Gallus gallus Dosal neuron-tube nuclear protein.; TR:Q8QHJ7
4	C17H11.4	C17H11.4	n/a	chrX 8,181,277	contains similarity to Drosophila melanogaster Flybase gene name is ari-1-PC;; FLYBASE:CG5659
5	F11C1.2	F11C1.2	n/a	chrX 12,986,446	contains similarity to Lactococcus lactis Rgg protein, putative.; TR:O87251
6	W04A8.6	W04A8.6	n/a	chrI 13,856,302	contains similarity to Interpro domain IPR011598 (Helix-loop-helix DNA-binding)
7	fsn-1	C26E6.5	n/a	chrIII 4,938,358	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins
8	T24C4.5	T24C4.5	n/a	chrIII 878,584	contains similarity to Pfam domain PF01896 Eukaryotic and archaeal DNA primase small subunit contains similarity to Interpro domains IPR014052 (DNA primase, small subunit, eukaryotic and archaeal), IPR002755 (DNA primase, small subunit)
9	nos-1	R03D7.7	n/a	chrII 10,952,444	nos-1 encodes an putative RNA-binding protein that contains a zinc-binding motif homologous to that of Drosophila Nanos, a posterior-group protein required for embryonic patterning and primordial germ cell development; in C. elegans, NOS-1 is required redundantly with NOS-2, a second Nanos homolog, for maintenance of germ cell viability during postembryonic development and for preventing primordial germ cells from dividing in the absence of food; nos-1 mRNA is expressed dynamically in the embryo, with early expression seen throughout the embryo and later expression restricted solely to germline blastomeres; nos-1 mRNA becomes undetectable after the 200-cell stage, but reappears later at the 550-cell stage; NOS-1 protein is not detectable in germline blastomeres until the 550-cell stage, suggesting that NOS-1 might actually function zygotically in germline specification.
10	C50B6.3	C50B6.3	n/a	chrV 13,314,685	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
11	try-1	ZK546.15	n/a	chrII 4,948,807	C. elegans TRY-1 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine), IPR008256 (Peptidase S1B, glutamyl endopeptidase I)
12	pie-1	Y49E10.14	n/a	chrIII 12,427,870	pie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6.
13	F43D2.1	F43D2.1	n/a	chrV 14,613,051	contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR015429 (Transcription regulator cyclin)
14	C27C12.3	C27C12.3	n/a	chrX 14,864,682	C27C12.3 encodes a novel protein that is conserved in C. elegans; three other genes related to C27C12.3 are present in tandem on the X chromosome; in situ hybridization studies indicate that C27C12.3 mRNA is expressed in the proximal germline.
15	tag-146	C27A12.3	n/a	chrI 6,039,839	C. elegans TAG-146 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
16	F01F1.11	F01F1.11	n/a	chrIII 5,870,989
17	pch-2	F10B5.5	n/a	chrII 8,159,065	pch-2 encodes a putative AAA+-type ATPase orthologous to budding yeast PCH2 and human TRIP13 (OMIM:604507); PCH-2 is required for the apoptosis of pachytene cells induced by unsynapsed chromosomal pairing centers, but is dispensable for meiotic apoptosis induced by DNA damage; PCH-2-mediated apoptosis is inhibited by SYP-1 and SYP-2, while it requires HIM-8 (and probably HIM-8's paralogs, ZIM-1/-3 and C02F5.12); however, PCH-2-mediated apoptosis does not require SPO-11; pch-2 transcripts are enriched during oogenesis; the excess germline apoptosis of syp-1(me17) mutants is partially suppressed by pch-2(tm1458), and fully suppressed by pch-2(tm1458);spo-11(ok79).
18	F22E5.9	F22E5.9	n/a	chrII 2,638,698
19	T03F6.3	T03F6.3	n/a	chrIII 13,390,012	contains similarity to Pfam domain PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase contains similarity to Interpro domains IPR006148 (Glucosamine/galactosamine-6-phosphate isomerase), IPR004547 (Glucosamine-6-phosphate isomerase)
20	C10A4.4	C10A4.4	n/a	chrX 7,402,753
21	R11H6.5	R11H6.5	n/a	chrV 14,611,457	contains similarity to Pfam domain PF07528 DZF contains similarity to Interpro domains IPR006561 (DZF), IPR006116 (2-5-oligoadenylate synthetase, ubiquitin-like region)
22	W03C9.2	W03C9.2	n/a	chrII 11,963,758	contains similarity to Schizosaccharomyces pombe Transcription elongation factor S-II (TFIIS).; SW:TFS2_SCHPO
23	pri-1	F58A4.4	n/a	chrIII 9,613,184	pri-1 encodes a homolog of the DNA polymerase alpha-primase subunit D that is required in embryos for the normal timing of embryonic cell divisions, much as DIV-1 is.
24	ZC477.5	ZC477.5	n/a	chrIV 7,102,332
25	F26H11.4	F26H11.4	n/a	chrII 14,410,374	contains similarity to Saccharomyces cerevisiae Mitochondrial ATPase (similar to E. coli FtsH protein) that resides in the innner mitochondrial membrane; SGD:YMR089C
26	C52B11.4	C52B11.4	n/a	chrX 1,285,532
27	ftr-1	Y113G7B.4	n/a	chrV 20,192,960	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
28	F16H11.3	F16H11.3	n/a	chrX 4,648,333	contains similarity to Pfam domain PF01733 Nucleoside transporter contains similarity to Interpro domains IPR002259 (Delayed-early response protein/equilibrative nucleoside transporter), IPR016196 (MFS general substrate transporter)
29	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
30	T04D3.1	T04D3.1	n/a	chrI 13,303,528	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
31	F29G9.7	F29G9.7	n/a	chrV 6,036,359	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
32	fem-3	C01F6.4	n/a	chrIV 9,106,267	fem-3 encodes a novel protein that promotes male development in all tissues.
33	tag-319	C30B5.1	n/a	chrII 6,200,135	C. elegans TAG-319 protein ;
34	T05B11.4	T05B11.4	n/a	chrV 7,753,022	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
35	F17C11.10	F17C11.10	n/a	chrV 10,963,667	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR009071 (High mobility group box, HMG), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
36	C50E3.13	C50E3.13	n/a	chrV 7,623,254
37	B0511.7	B0511.7	n/a	chrI 10,632,437	contains similarity to Pfam domain PF00498 FHA domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR000253 (Forkhead-associated)
38	T28A8.4	T28A8.4	n/a	chrIII 13,504,444	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
39	W01A8.5	W01A8.5	n/a	chrI 7,070,051	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
40	fbxa-108	F59A1.7	n/a	chrV 17,657,524	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
41	C25A1.1	C25A1.1	n/a	chrI 10,162,948	contains similarity to Danio rerio Novel protein (Zgc:65774).; TR:Q1LX81
42	R10D12.12	R10D12.12	n/a	chrV 13,961,624	contains similarity to Pfam domain PF04101 Glycosyltransferase family 28 C-terminal domain contains similarity to Interpro domain IPR007235 (Glycosyl transferase, family 28, C-terminal)
43	C02B10.2	C02B10.2	n/a	chrIV 5,090,651	contains similarity to Homo sapiens SNARE-associated protein Snapin; ENSEMBL:ENSP00000357674
44	T20D3.8	T20D3.8	n/a	chrIV 9,342,540	contains similarity to Pfam domain PF06432 Phosphatidylinositol N-acetylglucosaminyltransferase contains similarity to Interpro domain IPR009450 (Phosphatidylinositol N-acetylglucosaminyltransferase)
45	C16C8.13	C16C8.13	n/a	chrII 3,451,870	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
46	glp-1	F02A9.6	n/a	chrIII 9,095,873	glp-1 encodes an N-glycosylated transmembrane protein that, along with LIN-12, comprises one of two C. elegans members of the LIN-12/Notch family of receptors; from the N- to the C-terminus, GLP-1 is characterized by ten extracellular EGF-like repeats, three LIN-12/Notch repeats, a CC-linker, a transmembrane domain, a RAM domain, six intracellular ankyrin repeats, and a PEST sequence; in C. elegans, GLP-1 activity is required for cell fate specification in germline and somatic tissues; in the germline, GLP-1, acting as a receptor for the DSL family ligand LAG-2, is essential for mitotic proliferation of germ cells and maintenance of germline stem cells; in somatic tissues, maternally provided GLP-1, acting as a receptor for the DSL family ligand APX-1, is required for inductive interactions that specify the fates of certain embryonic blastomeres; GLP-1 is also required for some later embryonic cell fate decisions, and in these decisions its activity is functionally redundant with that of LIN-12; GLP-1 expression is regulated temporally and spatially via translational control, as GLP-1 mRNA, present ubiquitously in the germline and embryo, yields detectable protein solely in lateral, interior, and endomembranes of distal, mitotic germ cells, and then predominantly in the AB blastomere and its descendants in the early embryo; proper spatial translation of glp-1 mRNA in the embryo is dependent upon genes such as the par genes, that are required for normal anterior-posterior asymmetry in the early embryo; signaling through GLP-1 controls the activity of the downstream Notch pathway components LAG-3 and LAG-1, the latter being predicted to function as part of a transcriptional feedback mechanism that positively regulates GLP-1 expression; signaling through the DNA-binding protein LAG-1 is believed to involve a direct interaction between LAG-1 and the GLP-1 RAM and ankyrin domains
47	bath-41	F37A4.9	n/a	chrIII 6,721,274	The F37A4.9 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
48	F59A6.5	F59A6.5	n/a	chrII 5,001,644	contains similarity to Pfam domains PF00169 (PH domain) , PF00780 (CNH domain) , PF00130 (Phorbol esters/diacylglycerol binding domain (C1 domain)) contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR000533 (Tropomyosin), IPR001180 (Citron-like), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
49	F41G3.6	F41G3.6	n/a	chrII 6,743,499
50	let-99	K08E7.3	n/a	chrIV 12,569,200	let-99 encodes a protein with a DEP domain (Domain found in Dishevelled, Egl-10, and Pleckstrin); LET-99 has no obvious homologs in non-nematodes, but has a truncated paralog (LRG-1) in C. elegans; LET-99 is required for the mitotic spindle to be properly oriented with respect to the axis of cellular polarity, both during anterior migration and rotation of the nuclear-centrosome complex and during anaphase; let-99 mutants exhibit hyperactive nuclear movement and abnormal anaphase spindle pole behavior; LET-99 is mislocalized in par-2 and par-3 mutants; like other proteins containing DEP domains, LET-99 may act as part of a G protein signalling pathway (e.g., the one controlling spindle position).