UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nhr-257	C17A2.1	0	chrII 3,853,795	C. elegans NHR-257 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
2	mes-2	R06A4.7	n/a	chrII 14,386,115	mes-2 encodes a SET domain-containing protein that is orthologous to the Drosophila Polycomb group protein Enhancer of zeste [E(Z)]; as a member of a Polycomb-like chromatin repressive complex with MES-3 and MES-6, MES-2 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; in addition, MES-2 activity is required for normal levels and localization of MES-3 in >24-cell-stage embryos; MES-2 expression is detected in the primordial germ cells and germline nuclei throughout development, in all nuclei in early embryos, and in somatic nuclei, including those of the male tail, in L2 and L3 larvae; in the nucleus, MES-2 appears to localize to chromatin.
3	Y39F10A.2	Y39F10A.2	n/a	chrII 780,543	contains similarity to Pfam domain PF06079 Apyrase contains similarity to Interpro domain IPR009283 (Apyrase)
4	str-108	F10A3.13	n/a	chrV 16,166,795	C. elegans STR-108 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	F13H8.3	F13H8.3	n/a	chrII 6,264,731	contains similarity to Pfam domain PF01156 Inosine-uridine preferring nucleoside hydrolase contains similarity to Interpro domain IPR001910 (Inosine/uridine-preferring nucleoside hydrolase)
6	ilys-2	C45G7.2	n/a	chrIV 2,468,243	C. elegans ILYS-2 protein; contains similarity to Pfam domain PF05497 Destabilase contains similarity to Interpro domain IPR008597 (Destabilase)
7	W07G4.1	W07G4.1	n/a	chrV 13,033,814	contains similarity to Interpro domain IPR009050 ()
8	grl-21	ZC168.5	n/a	chrIV 10,737,774	grl-21 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-21 is expressed in arcade cells and hypodermis; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
9	ZK945.4	ZK945.4	n/a	chrII 10,104,330	contains similarity to Pfam domains PF00621 (RhoGEF domain) , PF00169 (PH domain) contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR015721 (Rho GTP exchange factor)
10	C44E4.5	C44E4.5	n/a	chrI 4,607,929	contains similarity to Pfam domain PF04969 CS domain contains similarity to Interpro domains IPR008978 (HSP20-like chaperone), IPR017447 (CS), IPR007052 (CS domain)
11	T27E9.6	T27E9.6	n/a	chrIII 13,475,636	contains similarity to Bradyrhizobium japonicum Bsl1006 protein.; TR:Q89VN9
12	secs-1	D1054.13	n/a	chrV 10,803,314	C. elegans SECS-1 protein; contains similarity to Pfam domain PF05889 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) contains similarity to Interpro domains IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR008829 (Soluble liver antigen/liver pancreas antigen)
13	F09G8.5	F09G8.5	n/a	chrIII 8,256,200	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal), IPR010916 (TonB box, conserved site)
14	srw-8	F59D6.5	n/a	chrV 3,033,490	C. elegans SRW-8 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
15	F26E4.5	F26E4.5	n/a	chrI 9,769,984	F26E4.5 encodes an SH2 domain-containing tyrosine kinase related to the vertebrate FER non-receptor protein tyrosine kinase; loss of F26E4.5 activity in an RNAi-hypersensitive strain results in axon guidance defects indicating that F26E4.5 likely plays a role in regulation of axon navigation.
16	W03H9.2	W03H9.2	n/a	chrII 14,144,403	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000046554
17	F28C10.1	F28C10.1	n/a	chrX 543,683
18	cyn-16	Y17G7B.9	n/a	chrII 12,032,664	cyn-16 encodes a highly diverged member of the cyclophilin family; CYN-16 exhibits low levels of peptidyl-prolyl cis/trans isomerase activity in vitro that is insensitive to the presence of cyclosporin A; a cyn-16::gfp fusion protein is expressed in the intestine during larval and adult stages of development, with particularly strong expression seen in the anterior and posterior ends; in dauer larvae, the cyn-16::gfp reporter is expressed in cell bodies and processes of ventral cord neurons and is no longer visible in the intestine.
19	K03B4.1	K03B4.1	n/a	chrV 4,690,455
20	kin-4	C10C6.1	n/a	chrIV 11,441,819	C. elegans KIN-4 protein; contains similarity to Pfam domains PF08926 (Domain of unknown function (DUF1908)) , PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR015022 (Region of unknown function DUF1908), IPR000719 (Protein kinase, core), IPR001478 (PDZ/DHR/GLGF), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
21	ulp-4	C41C4.6	n/a	chrII 8,132,271	C. elegans ULP-4 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
22	scrm-3	C04E12.7	n/a	chrV 3,356,584	scrm-3 encodes a putative phospholipid scramblase homologous to human PLSCR1-5, and paralogous to other C. elegans SCRMs (e.g., SCRM-1); SCRM-3 is expressed in neurons, anal depressor muscle, and occasionally in body wall muscle cells; however, in apoptotic germline cells, SCRM-3 is fully dispensable for normally rapid engulfment and largely dispensable for phosphatidylserine exposure; SCRM-3 does not bind WAH-1 in vitro, and scrm-3(tm631) mutants have no obvious phenotype.
23	C41A3.1	C41A3.1	n/a	chrX 5,427,831	contains similarity to Pfam domains PF02801 (Beta-ketoacyl synthase, C-terminal domain) (5), PF01370 (NAD dependent epimerase/dehydratase family) , PF08659 (KR domain) (2), PF00501 (AMP-binding enzyme) , PF00668 (Condensation domain) , PF00106 (short chain dehydrogenase) , PF00109 (Beta-ketoacyl synthase, N-terminal domain) (5), PF00550 (Phosphopantetheine attachment site) (8), PF00698 (Acyl transferase domain) (2)contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR006163 (Phosphopantetheine-binding), IPR001242 (Condensation domain), IPR016038 (Thiolase-like, subgroup), IPR013968 (Polyketide synthase, KR), IPR000794 (Beta-ketoacyl synthase), IPR001509 (NAD-dependent epimerase/dehydratase), IPR014031 (Beta-ketoacyl synthase, C-terminal), IPR014043 (Acyl transferase), IPR014030 (Beta-ketoacyl synthase, N-terminal), IPR008262 (Lipase, active site), IPR006162 (Phosphopantetheine attachment site), IPR000873 (AMP-dependent synthetase and ligase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016039 (Thiolase-like), IPR016040 (NAD(P)-binding), IPR009081 (Acyl carrier protein-like), IPR001227 (Acyl transferase region)
24	F52E10.3	F52E10.3	n/a	chrX 16,283,853	contains similarity to Salmonella typhimurium Secretion system apparatus protein ssaM.; SW:SSAM_SALTY
25	Y48A5A.1	Y48A5A.1	n/a	chrIV 1,967,552	contains similarity to Pfam domain PF04925 SHQ1 protein contains similarity to Interpro domain IPR007009 (SHQ1 protein)
26	W09D6.5	W09D6.5	n/a	chrIII 11,089,923	contains similarity to Saccharomyces cerevisiae cell wall integrity and stress response component 1; SGD:YOR008C
27	sre-9	C17E7.3	n/a	chrV 3,896,569	C. elegans SRE-9 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
28	btb-5	W05G11.5	n/a	chrIII 60,257	C. elegans BTB-5 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
29	osm-11	F11C7.5	n/a	chrX 17,420,817	C. elegans OSM-11 protein ;
30	pdhk-2	ZK370.5	n/a	chrIII 8,739,634	C. elegans PDHK-2 protein; contains similarity to Pfam domain PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase contains similarity to Interpro domains IPR005467 (Signal transduction histidine kinase, core), IPR004358 (Signal transduction histidine kinase-related protein, C-terminal), IPR003594 (ATP-binding region, ATPase-like)
31	F25B4.7	F25B4.7	n/a	chrV 5,686,614	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
32	cka-1	C28D4.2	n/a	chrIV 9,734,654	cka-1 encodes an isoform of choline kinase whose activity has been verified in vitro, and that has a strong preference for choline over ethanolamine; CKA-1 and CKA-2 comprise a related group ('A') of choline kinases.
33	nhr-135	VC5.5	0.00000000005	chrV 7,092,716	C. elegans NHR-135 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
34	str-166	T08B6.6	n/a	chrIV 4,885,569	C. elegans STR-166 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	clec-265	M02F4.7	n/a	chrX 3,032,455	C. elegans CLEC-265 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
36	F47E1.1	F47E1.1	n/a	chrX 9,075,645
37	T21H3.5	T21H3.5	n/a	chrV 1,159,760
38	C40H5.2	C40H5.2	n/a	chrX 11,754,976	contains similarity to Bifidobacterium longum Possible magnesium and cobalt transport protein.; TR:Q8G4E0
39	ZK697.8	ZK697.8	n/a	chrV 1,748,793	contains similarity to Pfam domain PF00576 HIUase/Transthyretin family contains similarity to Interpro domain IPR000895 (Transthyretin)
40	C05A9.3	C05A9.3	n/a	chrX 10,830,625	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
41	srh-116	Y61B8A.1	n/a	chrV 17,253,997	C. elegans SRH-116 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	M02A10.1	M02A10.1	n/a	chrX 707,178
43	M04B2.2	M04B2.2	n/a	chrIV 11,529,284	contains similarity to Pfam domains PF01170 (Putative RNA methylase family UPF0020) , PF02926 (THUMP domain) contains similarity to Interpro domains IPR004114 (THUMP), IPR001091 (Site-specific DNA-methyltransferase (cytosine-N4-specific)), IPR000241 (Putative RNA methylase)
44	str-185	R08C7.7	n/a	chrIV 4,428,740	C. elegans STR-185 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	lips-17	R07G3.2	n/a	chrII 7,609,466	C. elegans LIPS-17 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domains IPR002918 (Lipase, class 2), IPR008262 (Lipase, active site)
46	C15B12.6	C15B12.6	n/a	chrX 6,498,835
47	srw-121	K12D9.3	n/a	chrV 2,990,948	C. elegans SRW-121 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
48	srw-73	T03E6.6	n/a	chrV 16,587,756	C. elegans SRW-73 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
49	srw-83	ZK262.6	n/a	chrV 18,428,523	C. elegans SRW-83 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
50	str-170	T08B6.7	n/a	chrIV 4,878,848	C. elegans STR-170 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)