UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	math-9	C16C4.14	1e-153	chrII 1,890,347	C. elegans MATH-9 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
2	srv-9	F53F1.8	n/a	chrV 13,422,059	C. elegans SRV-9 protein ;
3	R05D7.1	R05D7.1	n/a	chrI 12,162,955	contains similarity to Kluyveromyces lodderae Truncated cytochrome oxidase subunit 2 (Fragment).; TR:Q7YG01
4	T10G3.4	T10G3.4	n/a	chrV 13,483,233	contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
5	F29A7.5	F29A7.5	n/a	chrII 2,747,560
6	K09C4.6	K09C4.6	n/a	chrX 3,275,175
7	D1005.6	D1005.6	n/a	chrX 1,463,763
8	F47G4.8	F47G4.8	n/a	chrI 14,053,124
9	hap-1	ZC395.7	n/a	chrIII 5,264,428	C. elegans HAP-1 protein; contains similarity to Pfam domain PF01725 Ham1 family contains similarity to Interpro domain IPR002637 (Ham1-like protein)
10	Y49F6C.8	Y49F6C.8	n/a	chrII 3,369,682
11	brc-2	T07E3.5	n/a	chrIII 6,901,783	brc-2 encodes a BRC domain-containing protein that is homologous to human BRCA2 which when mutated leads to early-onset breast cancer 2 or hereditary male breast cancer (OMIM:600185); in C. elegans, BRC-2 activity is essential for RAD-51-mediated repair of meiotic and radiation-induced double-strand breaks (DSBs); BRC-2 physically interacts with RAD-51 and single-stranded DNA and is required for proper localization of RAD-51 to sites of DNA damage and stabilization of RAD-51-DNA filaments; BRC-2 can also promote RAD-51-independent DSB repair via single-strand annealing (SSA) when the homologous recombination (HR) and nonhomologous end joining pathways (NHEJ) are compromised; in nonirradiated animals, BRC-2 is seen at diffuse, low levels in germline nuclei, but upon radiation treatment BRC-2 localizes to discrete foci that coincide with presumptive sites of DNA damage.
12	C14E2.2	C14E2.2	n/a	chrX 1,808,144	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
13	F25H2.3	F25H2.3	n/a	chrI 10,548,642	contains similarity to Interpro domain IPR002110 (Ankyrin)
14	F59B2.13	F59B2.13	n/a	chrIII 9,025,413	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
15	fbxa-112	Y102A5C.13	n/a	chrV 16,947,523	C. elegans FBXA-112 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
16	F55E10.5	F55E10.5	n/a	chrX 8,335,538
17	T11F9.13	T11F9.13	n/a	chrV 11,482,664	contains similarity to Thermotoga maritima ATP-dependent CLP protease, ATPase subunit.; TR:Q9WY41
18	ces-1	F43G9.11	n/a	chrI 8,634,989	ces-1 encodes a C2H2-type zinc finger transcription factor that is a member of the Snail family of proteins that includes Drosophila Scratch, Snail, and Slug, and human SNAIL and SLUG; although the normal function of CES-1 is not fully understood, gain-of-function mutations indicate that CES-1 can function as a transcriptional repressor that blocks programmed cell death in specific neurons by inhibiting expression of the cell-death activator EGL-1; in regulating EGL-1 expression, CES-1 appears to antagonize the transcriptional activity of the bHLH proteins, HLH-2 and HLH-3; despite its cell-type specific role in apoptosis, CES-1 expression is reportedly detected in many embryonic nuclei from the 100-cell stage of embryogenesis through the beginning of morphogenesis, with some CES-1 expression remaining at later embryonic stages; genetic studies indicate that CES-1 is negatively regulated by the bZIP transcription factor CES-2, which can bind CES-1 upstream sequences in vitro and thus may directly regulate CES-1 transcription in vivo
19	B0391.3	B0391.3	n/a	chrV 15,616,248	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000802 (Arsenical pump membrane protein)
20	F58F6.3	F58F6.3	n/a	chrIV 1,375,965
21	D1053.4	D1053.4	n/a	chrX 11,722,796	contains similarity to Naja kaouthia Cytotoxin 5 (Cytotoxin II).; SW:CX5_NAJKA
22	srj-55	Y45G12A.1	n/a	chrV 2,857,011	C. elegans SRJ-55 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	srj-40	F38H12.2	n/a	chrV 4,102,865	C. elegans SRJ-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	athp-1	C44B9.4	n/a	chrIII 10,887,899	C. elegans ATHP-1 protein; contains similarity to Pfam domains PF02178 (AT hook motif) (2), PF00628 (PHD-finger) contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000294 (Vitamin K-dependent carboxylation/gamma-carboxyglutamic region), IPR000253 (Forkhead-associated), IPR011011 (Zinc finger, FYVE/PHD-type)
25	K09F5.4	K09F5.4	n/a	chrX 7,710,385
26	C27D6.1	C27D6.1	n/a	chrII 5,174,657	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
27	T05B4.13	T05B4.13	n/a	chrV 4,126,750	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
28	nspc-14	F42F12.7	n/a	chrX 12,358,778	C. elegans NSPC-14 protein ;
29	twk-34	K06B4.12	n/a	chrV 15,707,216	C. elegans TWK-34 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
30	C28G1.4	C28G1.4	n/a	chrX 8,851,319	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
31	M01E5.2	M01E5.2	n/a	chrI 13,278,606	contains similarity to Pfam domains PF01018 (GTP1/OBG) , PF01926 (GTPase of unknown function) contains similarity to Interpro domains IPR014100 (GTP-binding protein Obg/CgtA), IPR005225 (Small GTP-binding protein), IPR006169 (GTP1/OBG subdomain), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG)
32	clec-168	F38A1.7	n/a	chrIV 1,258,213	C. elegans CLEC-168 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	T26C12.2	T26C12.2	n/a	chrIV 3,264,607	contains similarity to Interpro domain IPR001991 (Sodium:dicarboxylate symporter)
34	hlh-8	C02B8.4	n/a	chrX 8,118,315	The hlh-8 gene encodes a helix-loop-helix protein required for normal muscle development, and hence for normal defecation and egg-laying.
35	R53.2	R53.2	n/a	chrII 9,964,971	contains similarity to Pfam domain PF02223 Thymidylate kinase contains similarity to Interpro domain IPR000062 (Thymidylate kinase)
36	C18G1.7	C18G1.7	n/a	chrV 4,746,815	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR008166 (Protein of unknown function DUF23)
37	C46F2.1	C46F2.1	n/a	chrX 8,078,758
38	ccb-2	W10C8.1	n/a	chrI 2,848,257	C. elegans CCB-2 protein; contains similarity to Pfam domains PF00774 (Dihydropyridine sensitive L-type calcium channel (Beta subunit)) (2), PF00018 (SH3 domain) contains similarity to Interpro domains IPR000584 (Voltage-dependent calcium channel, L-type, beta subunit), IPR001452 (Src homology-3)
39	C30H6.9	C30H6.9	n/a	chrIV 17,379,717	contains similarity to Bacillus anthracis Hypothetical protein.; TR:Q81PV8
40	aqp-7	M02F4.8	n/a	chrX 3,026,113	aqp-7 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases either water or glycerol permeability five- to seven-fold; AQP-7 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its several paralogs; AQP-7 is expressed in muscle punctae (perhaps focal adhesions).
41	fip-5	F41E7.4	n/a	chrX 10,302,828	C. elegans FIP-5 protein; contains similarity to Interpro domain IPR000480 (Glutelin)
42	srg-59	C24B9.7	n/a	chrV 2,724,113	C. elegans SRG-59 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
43	str-185	R08C7.7	n/a	chrIV 4,428,740	C. elegans STR-185 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	srj-26	ZK262.10	n/a	chrV 18,422,252	C. elegans SRJ-26 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	sru-4	C33A12.10	n/a	chrIV 9,498,965	C. elegans SRU-4 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
46	F48C5.1	F48C5.1	n/a	chrX 11,445,448	contains similarity to Pfam domain PF00047 Immunoglobulin domain contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000742 (EGF-like, type 3), IPR007110 (Immunoglobulin-like), IPR013032 (EGF-like region, conserved site), IPR013151 (Immunoglobulin)
47	ZK546.5	ZK546.5	n/a	chrII 4,936,745	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
48	Y45F10D.4	Y45F10D.4	n/a	chrIV 13,784,287	Y45F10D.4 encodes a putative iron-sulfur cluster assembly enzyme that is required for embryonic and larval viability, and that is orthologous to human NIFUN and budding yeast ISU1 and ISU2; Y45F10D.4 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults; by orthology with yeast ISU1, Y45F10D.4 is predicted to bind FRH-1.
49	srt-65	C03A7.10	n/a	chrV 5,171,907	C. elegans SRT-65 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
50	sre-49	C50E10.9	n/a	chrII 12,319,870	C. elegans SRE-49 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)