UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C16C2.4	C16C2.4	6e-145	chrI 9,714,017	contains similarity to Pfam domain PF03909 BSD domain contains similarity to Interpro domain IPR005607 (BSD)
2	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	F37D6.3	F37D6.3	n/a	chrI 10,487,009	contains similarity to Interpro domain IPR002004 (Polyadenylate-binding protein/Hyperplastic disc protein)
4	lsd-1	T08D10.2	n/a	chrX 11,950,295	T08D10.2 encodes an ortholog of the human histone demethylase LSD1 (KIAA0601), and a paralog of C. elegans SPR-5; similar histone demethylase homologs are found in human, mouse, Drosophila, fission yeast, and Arabidopsis; T08D10.2 is predicted to demethylate histone H3 lysine 4 residues and act as a transcriptional corepressor.
5	gst-44	F13A7.10	n/a	chrV 16,391,643	gst-44 encodes a putative omega-class glutathione transferase (GST; EC 2.5.1.18) which, like its paralog GSTO-1, might have thiol oxidoreductase and dehydroascorbate reductase activity; GST-44 is expressed in excretory cell cytoplasm; other GST-44 paralogs include C02D5.3 and K10F12.4; GST-44 has no obvious function in mass RNAi assays.
6	C09D4.2	C09D4.2	n/a	chrI 5,492,333
7	dnj-24	W03A5.7	n/a	chrIII 5,417,808	This gene encodes a protein containing a DnaJ ('J') domain.
8	B0261.7	B0261.7	n/a	chrI 5,270,246
9	F36F12.4	F36F12.4	n/a	chrV 2,089,002	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
10	C45G9.2	C45G9.2	n/a	chrIII 5,069,704	contains similarity to Pfam domain PF01207 Dihydrouridine synthase (Dus) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR003733 (Thiamine monophosphate synthase), IPR001269 (Dihydrouridine synthase, DuS)
11	F40E3.3	F40E3.3	n/a	chrI 2,638,982
12	C27D8.4	C27D8.4	n/a	chrIV 12,705,410	contains similarity to Interpro domains IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
13	T15D6.10	T15D6.10	n/a	chrI 12,395,188	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
14	hpr-17	F32A11.2	n/a	chrII 13,155,162	C. elegans HPR-17 protein; contains similarity to Pfam domain PF03215 Rad17 cell cycle checkpoint protein contains similarity to Interpro domains IPR004582 (Checkpoint protein Rad24), IPR003593 (AAA+ ATPase, core)
15	F43G6.2	F43G6.2	n/a	chrII 11,782,680
16	sra-9	AH6.14	n/a	chrII 9,533,057	C. elegans SRA-9 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
17	srw-127	C33G8.1	n/a	chrV 7,013,646	C. elegans SRW-127 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
18	Y39E4B.7	Y39E4B.7	n/a	chrIII 13,113,204	contains similarity to Pfam domain PF01529 (DHHC zinc finger domain)
19	srh-104	F21H7.7	n/a	chrV 16,243,471	C. elegans SRH-104 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	Y39A1A.2	Y39A1A.2	n/a	chrIII 10,602,626	contains similarity to Oryza sativa Hypothetical protein.; TR:Q9LH25
21	VF39H2L.1	VF39H2L.1	n/a	chrI 8,645,323	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR010989 (t-SNARE), IPR000727 (Target SNARE coiled-coil region)
22	F48E8.6	F48E8.6	n/a	chrIII 5,444,858	contains similarity to Pfam domain PF00773 RNB domain contains similarity to Interpro domain IPR001900 (Ribonuclease II and R)
23	Y54G9A.5	Y54G9A.5	n/a	chrII 13,723,894
24	srh-222	F47C12.10	n/a	chrIV 3,980,509	C. elegans SRH-222 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	T12E12.3	T12E12.3	n/a	chrIV 5,543,170
26	M01E5.1	M01E5.1	n/a	chrI 13,275,251	contains similarity to Ichthyophthirius multifiliis Immobilization antigen isoform.; TR:Q9BMH3
27	F36D4.1	F36D4.1	n/a	chrV 9,418,520
28	T05B4.8	T05B4.8	n/a	chrV 4,115,949	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
29	fcd-2	Y41E3.9	n/a	chrIV 15,031,338	fcd-2 encodes an ortholog of the human gene FANCD2 (mutated in Fanconi anemia, OMIM:227646) that is strongly required for resistance to DNA interstrand crosslinking (ICL) agents, but not to ionizing radiation (IR); fcd-2 mutants are viable and dispensable for resistance to IR, meiotic recombination, and S-phase checkpoint activation, but are hypersensitive to ICL agents; like its human ortholog, FCD-2 is monoubiquitylated and recruited to chromosomal foci after ICL but not IR; transgenic expresssion of the FANCD2 gene in mutant FA-D2 cells rescues their abnormal sensitivity to mitomycin C, an agent that cross-links strands of DNA.
30	prx-14	R07H5.1	n/a	chrIV 11,183,588	C. elegans PRX-14 protein; contains similarity to Pfam domain PF04695 Peroxisomal membrane anchor protein (Pex14p) conserved region contains similarity to Interpro domain IPR006785 (Peroxisome membrane anchor protein Pex14p, N-terminal)
31	F46C5.4	F46C5.4	n/a	chrII 8,837,535
32	R10H10.6	R10H10.6	n/a	chrIV 10,409,131	contains similarity to Pfam domain PF01687 Riboflavin kinase contains similarity to Interpro domain IPR015865 (Riboflavin kinase)
33	C08A9.9	C08A9.9	n/a	chrX 17,107,104	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
34	djr-1.1	B0432.2	n/a	chrII 291,212	djr-1.1 encodes an ortholog of DJ-1 (OMIM:602533, mutated in early-onset Parkinson disease); DJR-1.1 is required for resistance to rotenone, a mitochondrial complex I inhibitors that mimics Parkinson disease (PD); djr-1.1(RNAi) animals are partly rescued from PD-like sensitivity by D-beta-hydroxybutyrate or tauroursodeoxycholic acid, and fully rescued by both; by orthology with DJ-1, DJR-1.1 may promote stability of the transcription factors SKN-1 or SKNR-1 (homologs of mammalian NFE2L2).
35	str-134	C05E4.6	n/a	chrV 744,563	C. elegans STR-134 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	C14F11.2	C14F11.2	n/a	chrX 6,211,298	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (6), PF00307 (Calponin homology (CH) domain) contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding), IPR003590 (Leucine-rich repeat, ribonuclease inhibitor subtype)
37	srgp-1	F12F6.5	n/a	chrIV 11,574,575	C. elegans SRGP-1 protein; contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00611 (Fes/CIP4 homology domain) contains similarity to Interpro domains IPR001060 (Cdc15/Fes/CIP4), IPR008936 (Rho GTPase activation protein), IPR000198 (RhoGAP)
38	str-6	T23D5.10	n/a	chrV 15,749,587	C. elegans STR-6 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
39	ceh-5	C16C2.1	n/a	chrI 9,727,604	ceh-5 encodes a homeodomain protein, similar to the human VENTRAL ANTERIOR HOMEO BOX 2 gene (VAX2; OMIM:604295); CEH-5 is dispensable for viability and gross morphology.
40	T26A5.6	T26A5.6	n/a	chrIII 6,449,449	contains similarity to Interpro domain IPR001194 (DENN)
41	T20G5.9	T20G5.9	n/a	chrIII 10,210,308	contains similarity to Pfam domain PF09282 Mago binding contains similarity to Interpro domain IPR015362 (Exon junction complex, Pym)
42	T27F6.4	T27F6.4	n/a	chrI 12,485,310	contains similarity to Saccharomyces cerevisiae Mid-Two Like 1; SGD:YGR023W
43	C27F2.5	C27F2.5	n/a	chrIII 4,961,124	C27F2.5 encodes the C. elegans ortholog of the conserved vacuolar protein sorting protein EAP30/SNF8/VPS22; by homology, the product of C27F2.5 is predicted to be a component of an ESCRT-II complex (Endosomal Sorting Complex Required for Transport) that functions in endosomal transport.
44	ced-6	F56D2.7	n/a	chrIII 5,596,872	ced-6 encodes an Src homology (SH) 3 and phosphotyrosine-binding (PTB) domain-containing adaptor protein, orthologous to human CED-6/GULP, that is required for cell corpse engulfment during apoptosis; CED-6 is bound by the phosphotyrosine binding motif in the cytoplasmic tail of the transmembrane protein CED-1, and and within phagocytic cells this interaction may be part of a signal transduction pathway that promotes apoptotic cell engulfment.
45	srj-26	ZK262.10	n/a	chrV 18,422,252	C. elegans SRJ-26 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	hlh-8	C02B8.4	n/a	chrX 8,118,315	The hlh-8 gene encodes a helix-loop-helix protein required for normal muscle development, and hence for normal defecation and egg-laying.
47	sdz-15	F23F12.4	n/a	chrIII 6,499,273	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
48	Y40B1A.2	Y40B1A.2	n/a	chrI 13,348,157	contains similarity to Pfam domain PF00397 WW domain contains similarity to Interpro domains IPR002349 (WW), IPR001202 (WW/Rsp5/WWP)
49	R17.3	R17.3	n/a	chrIII 10,836,977	R17.3 encodes an ortholog of human retinal pigment epithelium (RPE)-spondin (RPESP).
50	C01H6.9	C01H6.9	n/a	chrI 7,231,276	C01H6.9 encodes a homolog of haploid germ cell-specific nuclear protein kinase (haspin) that specifically binds GOA-1 in yeast two-hybrid assays; C01H6.9 is expressed in PHB sensory neurons and PVT interneurons in the tail, several unidentified neurons in the head (with projections to the nose and nerve ring), and intestinal cells, with mainly nuclear localization; C01H6.9 has no obvious function or phenotype in RNAi assays, either alone or with inactivation of a close paralog (F22H10.5).