UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ccdc-55	C16C10.6	9.999999999999999e-169	chrIII 4,167,827	C. elegans CCDC-55 protein ; contains similarity to Mus musculus Coiled-coil domain-containing protein 55.; SW:Q5NCR9
2	K08D9.5	K08D9.5	n/a	chrV 3,225,335	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
3	C24H10.4	C24H10.4	n/a	chrX 5,058,527
4	Y49A10A.1	Y49A10A.1	n/a	chrX 10,359,445	contains similarity to Pfam domain PF06565 Repeat of unknown function (DUF1126) contains similarity to Interpro domains IPR010554 (Protein of unknown function DUF1126), IPR006602 (Region of unknown function DM10)
5	sqv-3	R10E11.4	n/a	chrIII 9,779,478	sqv-3 encodes a beta(1,4)-galactosyltransferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos, vulval morphogenesis, and chondroitin synthesis; SQV-3 is orthologous to human human galactosyltransferase I (B4GALT7; OMIM:604327, mutated in the progeroid form of Ehlers-Danlos syndrome); sqv-3 transgenically rescues hamster cells lacking galactosyl transferase I; the common requirement for SQV-3 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
6	Y57G7A.8	Y57G7A.8	n/a	chrII 1,291,464
7	R11H6.4	R11H6.4	n/a	chrV 14,610,325	contains similarity to Homo sapiens Steerin3 protein; ENSEMBL:ENSP00000228327
8	str-227	C07G3.3	n/a	chrV 3,518,993	C. elegans STR-227 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	F27B3.5	F27B3.5	n/a	chrIII 6,560,937	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
10	T19H5.1	T19H5.1	n/a	chrII 9,473,432	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
11	C01G5.5	C01G5.5	n/a	chrIV 6,525,508	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
12	C09G9.7	C09G9.7	n/a	chrIV 8,878,734	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
13	W05H7.2	W05H7.2	n/a	chrX 1,435,503
14	F53F8.5	F53F8.5	n/a	chrV 20,697,686	contains similarity to Pfam domain PF00536 SAM domain (Sterile alpha motif) contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR013761 (Sterile alpha motif-type), IPR001660 (Sterile alpha motif SAM)
15	F46F11.8	F46F11.8	n/a	chrI 5,625,448
16	F36G9.3	F36G9.3	n/a	chrV 15,958,350	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF05978 (Eukaryotic protein of unknown function (DUF895)) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
17	C36F7.2	C36F7.2	n/a	chrI 9,551,413	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
18	F14D2.8	F14D2.8	n/a	chrII 3,348,717	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
19	F14H12.7	F14H12.7	n/a	chrX 4,362,080
20	mom-4	F52F12.3	n/a	chrI 9,898,245	mom-4 encodes a MAP kinase kinase kinase-related protein orthologous to Drosophila Tak1 and the vertebrate MAPKKK7 proteins; during embryonic development, mom-4 activity is required for positive regulation of the Wnt pathway signaling that governs anterior/posterior (A/P) polarity: MOM-4 stimulates the WRM-1/LIT-1-dependent phosphorylation of POP-1, a TCF/LEF-related transcription factor, leading to its downregulation in posterior daughters of A/P cell divisions.
21	T05H10.1	T05H10.1	n/a	chrII 8,044,949	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR011051 (Cupin, RmlC-type)
22	F33G12.2	F33G12.2	n/a	chrII 5,030,810	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
23	F56H6.4	F56H6.4	n/a	chrI 12,291,320	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
24	fbxa-56	T12B5.7	n/a	chrIII 937,668	C. elegans FBXA-56 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
25	ulp-5	K02F2.4	n/a	chrI 6,813,375	C. elegans ULP-5 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
26	fkh-6	B0286.5	n/a	chrII 4,381,579	fkh-6 encodes one of 15 C. elegans forkhead transcription factors; fkh-6 is required for several aspects of male gonadogenesis including asymmetric cell division, cell migration and sex determination and appears to act downstream of tra-1; FKH-6 is specifically expressed in the gonad.
27	F48E8.2	F48E8.2	n/a	chrIII 5,466,142	contains similarity to Mus musculus E2F-associated phosphoprotein (EAPP).; SW:Q5BU09
28	srh-215	T20B3.3	n/a	chrV 16,831,260	C. elegans SRH-215 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001356 (Homeobox)
29	F52C6.3	F52C6.3	n/a	chrII 1,925,233	contains similarity to Interpro domain IPR000626 (Ubiquitin)
30	nex-3	C28A5.3	n/a	chrIII 4,443,071	nex-3 encodes an annexin, a member of a family of calcium-dependent phospholipid binding proteins; by homology, NEX-3 could function in a number of processes, such as membrane fusion, cytoskeletal interactions, and intracellular signaling; however, as loss of nex-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of NEX-3 in C. elegans development and/or behavior is not yet known.
31	C10B5.3	C10B5.3	n/a	chrV 8,584,165
32	C42C1.8	C42C1.8	n/a	chrIV 12,292,136	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
33	F54D10.4	F54D10.4	n/a	chrII 3,806,515
34	rab-21	T01B7.3	n/a	chrII 8,714,514	rab-21 encodes a Rab GTPase most closely related to the Drosophila and vertebrate Rab21 GTPases and Saccharomyces cerevisiae VPS21; by homology, RAB-21 is predicted to be involved in membrane trafficking/vesicle transport; loss of rab-21 activity via RNAi results in 7-8% embryonic lethality.
35	F26H9.4	F26H9.4	n/a	chrI 9,306,326	contains similarity to Pfam domain PF01467 Cytidylyltransferase contains similarity to Interpro domains IPR005248 (Probable nicotinate-nucleotide adenylyltransferase), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004820 (Cytidylyltransferase)
36	C53D6.6	C53D6.6	n/a	chrIV 9,030,151	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
37	W09C5.1	W09C5.1	n/a	chrI 13,627,524	contains similarity to Pfam domain PF01201 Ribosomal protein S8e contains similarity to Interpro domain IPR001047 (Ribosomal protein S8e)
38	F55B11.3	F55B11.3	n/a	chrIV 14,425,099	contains similarity to Lactococcus lactis Unknown protein.; TR:Q9CF31
39	sqv-7	C52E12.3	n/a	chrII 7,011,690	The sqv-7 gene encodes a nucleotide-sugar transporter of the Golgi membrane, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-7 promotes glycosaminoglycan biosynthesis by translocating UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-galactose into the lumen of the Golgi apparatus; SQV-7 is biochemically active when transgenically expressed in yeast or mammalian Golgi membranes; the common requirement for SQV-7 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
40	math-7	C16C4.12	n/a	chrII 1,885,961	C. elegans MATH-7 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
41	M116.1	M116.1	n/a	chrIV 8,411,585
42	hop-1	C18E3.8	n/a	chrI 4,209,468	hop-1 encodes one of three C. elegans presenilins (the other two presenilins are encoded by sel-12 and spe-4); originally identified on the basis of its sequence similarity to SEL-12 and the human PS1 and PS2 presenilins, HOP-1 has been shown to function redundantly with SEL-12 in embryonic, larval, and germline development and thus, to likely function by regulating LIN-12/GLP-1 signaling; in addition, hop-1 can functionally substitute for sel-12 by rescuing the egg-laying and vulval development defects of sel-12 mutants; hop-1 transcription appears to be regulated, at least in part, by the C. elegans spr genes, some of which encode orthologs of the mammalian CoREST repressor complex.
43	W06B4.1	W06B4.1	n/a	chrII 4,472,468
44	ztf-9	ZK287.6	n/a	chrV 9,691,558	C. elegans ZTF-9 protein; contains similarity to Interpro domain IPR015880 (Zinc finger, C2H2-like)
45	F53F10.3	F53F10.3	n/a	chrI 3,827,677	contains similarity to Pfam domain PF03650 Uncharacterised protein family (UPF0041) contains similarity to Interpro domain IPR005336 (Protein of unknown function UPF0041)
46	ZK1248.13	ZK1248.13	n/a	chrII 5,830,927
47	T15D6.10	T15D6.10	n/a	chrI 12,395,188	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
48	sra-9	AH6.14	n/a	chrII 9,533,057	C. elegans SRA-9 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
49	F25H9.7	F25H9.7	n/a	chrV 13,468,733	contains similarity to Pfam domain PF05882 ACN9 family contains similarity to Interpro domain IPR008381 (ACN9)
50	str-5	T23D5.12	n/a	chrV 15,753,810	C. elegans STR-5 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)