UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C16A11.3	C16A11.3	0	chrII 4,231,931	contains similarity to Pfam domains PF04435 (Domain of unknown function (DUF545)) , PF00069 (Protein kinase domain) , PF00628 (PHD-finger) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR006570 (SPK), IPR002290 (Serine/threonine protein kinase), IPR001965 (Zinc finger, PHD-type), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011011 (Zinc finger, FYVE/PHD-type)
2	rec-8	W02A2.6	n/a	chrIV 13,351,138	rec-8 encodes a meiosis-specific cohesin complex subunit orthologous to Saccharomyces cerevisiae and Schizosaccharomyces pombe Rec8p; REC-8 is essential for pairing of homologoues and sister chromatids during meiosis and thus for proper chromosome disjunction; in the germline, REC-8 associates with chromatin of transition zone nuclei, and co-localizes with SMC-1 along the longitudinal axes of synapsed chromosomes at pachytene and in a cruciform pattern at diakinesis; REC-8 localization to chromatin is dependent upon TIM-1, a HEAT/Armadillo repeat-containing protein related to Drosophila TIMELESS, and additionally, REC-8 and SCC-3 are mutually required for chromatin localization; REC-8 cleavage and degradation during meiosis I is dependent on the AIR-2 aurora-like kinase and during meiosis II on AIR-2 and the PLK-1 polo-like kinase.
3	C18E9.4	C18E9.4	n/a	chrII 8,964,490	C18E9.4 encodes the C. elegans ortholog of the NDUFB3/B12 subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I).
4	R11A8.1	R11A8.1	n/a	chrIV 10,356,114	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000299601
5	prg-1	D2030.6	n/a	chrI 7,586,932	C. elegans PRG-1 protein; contains similarity to Pfam domains PF02170 (PAZ domain) , PF02171 (Piwi domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
6	syp-1	F26D2.2	n/a	chrV 16,406,704	C. elegans SYP-1 protein ; contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_7, whole genome shotgun sequence.; TR:A0DYW0
7	bath-1	F59H6.9	n/a	chrII 2,028,219	C. elegans BATH-1 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
8	C47E8.4	C47E8.4	n/a	chrV 14,684,638	contains similarity to Pfam domain PF04921 XAP5 protein contains similarity to Interpro domains IPR007005 (XAP5 protein), IPR000533 (Tropomyosin)
9	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
10	xtr-2	F17A2.1	n/a	chrX 12,316,529	xtr-2 encodes a protein with similarity to TRA-2A and TRA-2B in a region known as the MX region, hypothesized to be a protein-protein interaction domain involved in negatively regulating tra-2 activity in the germ line.
11	T01G1.3	T01G1.3	n/a	chrIV 11,368,676	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR000694 (Proline-rich region), IPR002110 (Ankyrin), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
12	B0273.3	B0273.3	n/a	chrIV 5,485,115	contains similarity to Tetraodon nigroviridis Chromosome 18 SCAF15038, whole genome shotgun sequence. (Fragment).; TR:Q4RJG8
13	col-141	T15B7.5	n/a	chrV 6,830,181	C. elegans COL-141 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
14	col-103	F56B3.1	n/a	chrIV 763,047	C. elegans COL-103 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR000817 (Prion protein), IPR008160 (Collagen triple helix repeat), IPR013286 (Annexin, type VII)
15	F02D8.4	F02D8.4	n/a	chrV 14,986,177	contains similarity to Pfam domain PF00246 Zinc carboxypeptidase contains similarity to Interpro domains IPR000834 (Peptidase M14, carboxypeptidase A), IPR009020 (Proteinase inhibitor, propeptide)
16	C14C10.5	C14C10.5	n/a	chrV 12,603,773	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR016024 (Armadillo-type fold)
17	coq-8	C35D10.4	n/a	chrIII 4,865,152	coq-8 encodes a putative protein kinase orthologous to ABC1 (COQ8) from S. cerevisiae and UbiB from E. coli, and paralogous to C. elegans D2023.6 and its (uncharacterized) eukaryotic orthologs; COQ-8 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; alternative hypotheses for COQ-8's biochemical function are that it is a 2-polyprenylphenol 6-hydroxylase, or that it may activate proteins necessary for monooxygenase activity via phosphorylation; coq-8 is expressed in several tissues during larval development, but in later adult life its expression is restricted to neurons; coq-8 mutants have slowed pharyngeal pumping, and eventually arrest as paralysed larvae before dying; coq-8(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans; coq-8 mutants are not rescued by dietary coenzyme Q.
18	msh-2	H26D21.2	n/a	chrI 3,695,931	The msh-2 gene encodes a DNA mismatch repair protein homolog that is orthologous to human MSH2 (OMIM:120435); mutation of the human MSH2 gene leads to hereditary non-polyposis colon cancer (OMIM:120436).
19	C36A4.5	C36A4.5	n/a	chrIII 3,846,247	contains similarity to Interpro domains IPR003993 (Treacher Collins syndrome, treacle), IPR000694 (Proline-rich region), IPR005819 (Histone H5)
20	F52B5.3	F52B5.3	n/a	chrI 8,321,160	The F52B5.3 gene encodes a DEAH helicase orthologous to the Drosophila SpindleE protein.
21	C01H6.4	C01H6.4	n/a	chrI 7,211,559	contains similarity to Pfam domains PF00070 (Pyridine nucleotide-disulphide oxidoreductase) , PF00743 (Flavin-binding monooxygenase-like) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000759 (Adrenodoxin reductase), IPR000960 (Flavin-containing monooxygenase FMO), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
22	R07E5.13	R07E5.13	n/a	chrIII 4,414,076	This gene encodes a homolog of mammalian BRAIN PROTEIN 44-LIKE (BRP44L).
23	W07G4.4	W07G4.4	n/a	chrV 13,045,013	contains similarity to Pfam domain PF00883 Cytosol aminopeptidase family, catalytic domain contains similarity to Interpro domain IPR000819 (Peptidase M17, leucyl aminopeptidase, C-terminal)
24	C44E4.3	C44E4.3	n/a	chrI 4,639,174	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR004838 (Aminotransferases, class-I, pyridoxal-phosphate-binding site), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
25	ZK1193.2	ZK1193.2	n/a	chrX 411,499	contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR002049 (EGF-like, laminin), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans), IPR002035 (von Willebrand factor, type A)
26	W01A11.1	W01A11.1	n/a	chrV 6,500,809	contains similarity to Pfam domains PF06441 (Epoxide hydrolase N terminus) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR016292 (Epoxide hydrolase), IPR000073 (Alpha/beta hydrolase fold-1), IPR000639 (Epoxide hydrolase-like), IPR010497 (Epoxide hydrolase, N-terminal)
27	C35D10.5	C35D10.5	n/a	chrIII 4,862,879	contains similarity to Pfam domain PF03981 Ubiquinol-cytochrome C chaperone contains similarity to Interpro domain IPR007129 (Ubiquinol-cytochrome C chaperone)
28	C03B8.2	C03B8.2	n/a	chrIII 7,716,234
29	C28A5.1	C28A5.1	n/a	chrIII 4,431,952	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IJR3
30	dog-1	F33H2.1	n/a	chrI 15,020,116	dog-1 encodes a predicted DEAH helicase, orthologous to the human BRCA1-binding protein BACH1 (OMIM:605882, mutated in early-onset breast cancer); DOG-1 is required for maintenance of polyguanine tracts of germline and somatic DNA, and is proposed to resolve the secondary structure that can occur in guanine-rich DNA during lagging-strand DNA synthesis.
31	C18H2.2	C18H2.2	n/a	chrIII 7,679,866	contains similarity to Interpro domain IPR008962 (PapD-like)
32	B0495.2	B0495.2	0.0000000004	chrII 7,700,550	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core)
33	F29C4.6	F29C4.6	n/a	chrIV 120,551	contains similarity to Pfam domain PF01171 PP-loop family contains similarity to Interpro domains IPR011063 (PP-loop), IPR012089 (PP-loop ATPase, YdaO-related), IPR000541 (Protein of unknown function UPF0021), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold)
34	ugt-44	F01D4.2	n/a	chrIV 10,470,798	C. elegans UGT-44 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
35	ZC317.7	ZC317.7	n/a	chrV 5,469,825	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003980 (Histamine H3 receptor)
36	F07A11.5	F07A11.5	n/a	chrII 11,613,153	contains similarity to Pfam domain PF00294 pfkB family carbohydrate kinase contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR011877 (Ribokinase, bacterial), IPR002139 (Ribokinase)
37	F54D5.2	F54D5.2	n/a	chrII 11,573,977	contains similarity to Interpro domain IPR000194 (ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)
38	F08F8.2	F08F8.2	n/a	chrIII 7,360,724	contains similarity to Pfam domain PF00368 Hydroxymethylglutaryl-coenzyme A reductase contains similarity to Interpro domains IPR004554 (Hydroxymethylglutaryl-CoA reductase, class I, catalytic), IPR009029 (Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding), IPR002202 (Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)
39	rde-1	K08H10.7	n/a	chrV 9,989,751	rde-1 encodes a novel, conserved protein that is a member of the PIWI/STING/Argonaute/Zwille/eIF2c family of proteins; rde-1 activity is required for RNA-mediated interference (RNAi), likely at a point after small interfering RNAs (siRNAs) have been produced from dsRNA triggers; RDE-1 interacts with RDE-4 in vivo and its activity is also required for accumulation of dsRNA bound to RDE-4.
40	fzo-1	ZK1248.14	n/a	chrII 5,834,733	C. elegans FZO-1 protein; contains similarity to Pfam domain PF04799 fzo-like conserved region contains similarity to Interpro domains IPR006884 (Fzo-like conserved region), IPR001019 (Guanine nucleotide binding protein (G-protein), alpha subunit)
41	C29F4.2	C29F4.2	n/a	chrIV 11,228,390	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
42	vps-33.2	C56C10.1	n/a	chrII 6,602,269	C. elegans VPS-33.2 protein; contains similarity to Pfam domain PF00995 Sec1 family contains similarity to Interpro domain IPR001619 (Sec1-like protein)
43	F10F2.2	F10F2.2	n/a	chrIII 4,631,042	contains similarity to Pfam domains PF02769 (AIR synthase related protein, C-terminal domain) (2), PF00586 (AIR synthase related protein, N-terminal domain) contains similarity to Interpro domains IPR016188 (PurM, N-terminal-like), IPR001220 (Legume lectin, beta domain), IPR000728 (AIR synthase related protein), IPR010073 (Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria), IPR010918 (AIR synthase related protein, C-terminal), IPR002016 (Haem peroxidase, plant/fungal/bacterial)
44	T28A8.3	T28A8.3	0.000002	chrIII 13,507,200	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
45	F13D12.5	F13D12.5	n/a	chrII 11,727,540	contains similarity to Interpro domain IPR001814 (Filamentous bacteriophage Vg4 protein)
46	mut-14	C14C11.6	n/a	chrV 5,659,724	mut-14 mutants exhibit germline transposon activation, a deficient response to RNAi, resistance to co-suppression, and transgene desilencing.
47	dpf-5	R11E3.8	n/a	chrIV 4,804,689	dpf-5 encodes a putative acylamino-acid-releasing enzyme (AARE; EC 3.4.19.1), orthologous to human APEH, with no obvious function in mass RNAi assays.
48	C50F7.4	C50F7.4	n/a	chrIV 7,729,765	contains similarity to Pfam domains PF08442 (ATP-grasp domain) , PF00549 (CoA-ligase) contains similarity to Interpro domains IPR013650 (ATP-grasp fold, succinyl-CoA synthetase-type), IPR005811 (ATP-citrate lyase/succinyl-CoA ligase), IPR005809 (Succinyl-CoA synthetase, beta subunit), IPR013815 (ATP-grasp fold, subdomain 1), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR013816 (ATP-grasp fold, subdomain 2), IPR016102 (Succinyl-CoA synthetase-like)
49	F33H2.2	F33H2.2	n/a	chrI 15,025,433	contains similarity to Homo sapiens Protein FAM91A1; ENSEMBL:ENSP00000335082
50	C05D11.1	C05D11.1	n/a	chrIII 6,438,225	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)