UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	dhs-22	C15H11.4	7e-180	chrV 14,420,734	dhs-22 encodes a short-chain dehydrogenase predicted to be mitochondrial.
2	M02B7.2	M02B7.2	n/a	chrIV 3,804,264	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	C36B1.7	C36B1.7	n/a	chrI 8,736,564	contains similarity to Pfam domain PF00186 Dihydrofolate reductase contains similarity to Interpro domain IPR001796 (Dihydrofolate reductase region)
5	Y102A5C.4	Y102A5C.4	n/a	chrV 16,923,224	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)
6	R13A5.7	R13A5.7	n/a	chrIII 7,568,723
7	wdfy-2	D2013.2	n/a	chrII 9,320,794	wdfy-2 encodes a WD40- and FYVE-domain containing protein that is orthologous to mammalian WDFY2; WDFY-2 is one of twelve C. elegans FYVE-domain-containing proteins; wdfy-2 activity is essential for wild-type levels of endocytosis.
8	T09A5.9	T09A5.9	n/a	chrII 7,858,979	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal)
9	F46F11.8	F46F11.8	n/a	chrI 5,625,448
10	K07A12.2	K07A12.2	n/a	chrI 8,678,985	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
11	ZK1248.15	ZK1248.15	n/a	chrII 5,837,633	contains similarity to Pfam domain PF00397 WW domain contains similarity to Interpro domains IPR006596 (Nucleotide binding protein, PINc), IPR001202 (WW/Rsp5/WWP)
12	C53B7.7	C53B7.7	n/a	chrX 6,862,206	C53B7.7 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C53B7.7 has no clear orthologs in other organisms.
13	spd-3	H34C03.1	n/a	chrIV 6,763,933	C. elegans SPD-3 protein ;
14	dhs-1	C01G8.3	6e-23	chrI 5,280,165	C. elegans DHS-1 protein; contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
15	C01G10.7	C01G10.7	n/a	chrV 15,086,381	contains similarity to Pfam domain PF03328 HpcH/HpaI aldolase/citrate lyase family contains similarity to Interpro domains IPR011206 (Citrate lyase, beta subunit), IPR005000 (HpcH/HpaI aldolase), IPR015813 (Pyruvate/Phosphoenolpyruvate kinase, catalytic core)
16	K04G2.2	K04G2.2	n/a	chrI 8,031,912	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q17GK3
17	H14A12.3	H14A12.3	n/a	chrIII 7,464,450	H14A12.3 encodes an ortholog of S. cerevisiae RAV2; like RAV2, H14A12.3 may be required for the reassociation of vacuolar proton-translocating ATPase (V-ATPase) after temporary glucose starvation.
18	tbg-1	F58A4.8	n/a	chrIII 9,627,816	tbg-1 encodes gamma-tubulin; in C. elegans, tbg-1 activity is essential and is required for normal bipolar spindle assembly and function, as well as the fast phase of female pronuclear migration following fertilization; while tbg-1 is required for proper organization and function of kinetochore and interpolar microtubules, it does not appear to be absolutely required for microtubule nucleation and growth; TBG-1 localizes to centrosomes in both interphase and mitotic cells, exhibiting a dynamic behavior during mitosis that differs between anterior and posterior centrosomes.
19	C35D10.6	C35D10.6	n/a	chrIII 4,859,975	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
20	R11A8.2	R11A8.2	n/a	chrIV 10,359,115	contains similarity to Interpro domains IPR008991 (Translation protein SH3-like), IPR005824 (KOW), IPR000467 (D111/G-patch)
21	R144.5	R144.5	n/a	chrIII 5,000,320	contains similarity to Homo sapiens Isoform 1 of Smith-Magenis syndrome chromosomal region candidate gene 8 protein; ENSEMBL:ENSP00000379048
22	C16A11.5	C16A11.5	n/a	chrII 4,224,777	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
23	T02E1.2	T02E1.2	n/a	chrI 8,221,514	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IJZ2
24	F11A10.5	F11A10.5	n/a	chrIV 12,095,498	contains similarity to Pfam domain PF04184 ST7 protein contains similarity to Interpro domain IPR007311 (ST7)
25	ZK1067.3	ZK1067.3	n/a	chrII 9,224,144	contains similarity to Mus musculus Serine/threonine-protein kinase Nek9 (EC 2.7.1.37) (NimA-relatedsprotein kinase 9).; SW:NEK9_MOUSE
26	prpf-4	F22D6.5	n/a	chrI 7,092,922	C. elegans PRPF-4 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
27	bath-4	F52C6.8	n/a	chrII 1,917,377	C. elegans BATH-4 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
28	C25D7.8	C25D7.8	n/a	chrV 15,066,857	contains similarity to Interpro domains IPR003323 (Ovarian tumour, otubain), IPR016615 (Ubiquitin thioesterase Otubain)
29	T13F2.2	T13F2.2	n/a	chrIV 9,797,072	contains similarity to Pfam domain PF02229 Transcriptional Coactivator p15 (PC4) contains similarity to Interpro domains IPR003173 (Transcriptional coactivator p15), IPR009044 (ssDNA-binding transcriptional regulator)
30	F13G3.6	F13G3.6	n/a	chrI 7,304,082	contains similarity to Pfam domain PF00535 Glycosyl transferase family 2 contains similarity to Interpro domains IPR001173 (Glycosyl transferase, family 2), IPR016040 (NAD(P)-binding)
31	efn-3	F15A2.5	n/a	chrX 13,476,463	efn-3 encodes a potential GPI-modified ephrin that is, with EFN-2, is required for normal epidermal organization in the male tail; EFN-3, along with EFN-1 and EFN-2, activates the VAB-1 tyrosine kinase in vivo and binds it in vitro, and has a minor role in embryonic epiboly.
32	M01E11.2	M01E11.2	n/a	chrI 5,580,733	contains similarity to Pfam domain PF08216 Eukaryotic domain of unknown function (DUF1716) contains similarity to Interpro domains IPR013180 (Protein of unknown function DUF1716, eukaryotic), IPR011989 (Armadillo-like helical), IPR000225 (Armadillo), IPR016024 (Armadillo-type fold)
33	W04A4.6	W04A4.6	n/a	chrI 13,686,458	contains similarity to Oryza sativa P0005A05.15 protein.; TR:Q9FTN4
34	fbxa-22	T12B5.5	n/a	chrIII 939,140	C. elegans FBXA-22 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
35	R07E5.1	R07E5.1	n/a	chrIII 4,410,321	contains similarity to Pfam domains PF07713 (Protein of unknown function (DUF1604)) , PF01585 (G-patch domain) contains similarity to Interpro domains IPR011666 (Protein of unknown function DUF1604), IPR000467 (D111/G-patch), IPR005398 (Tubby, N-terminal)
36	tre-3	W05E10.4	n/a	chrV 11,712,817	tre-3 encodes one of four putative trehalases in C. elegans of unknown function, as RNAi analysis has not produced an obvious phenotype; expressed throughout development.
37	C34B2.5	C34B2.5	n/a	chrI 10,675,986	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013026 (Tetratricopeptide region)
38	M01G5.1	M01G5.1	n/a	chrIII 1,503,267	contains similarity to Homo sapiens hypothetical protein; VG:OTTHUMP00000024537
39	T01B7.6	T01B7.6	n/a	chrII 8,723,943	contains similarity to Interpro domain IPR000694 (Proline-rich region)
40	apc-2	K06H7.6	n/a	chrIII 8,082,080	apc-2 encodes an ortholog of subunit 2 of anaphase-promoting complex (APC, a cyclin-specific E3 RING ubiquitin ligase); APC-2 and S. cerevisiae's Apc2p have 32% identity in their cullin domains (considered crucial for function), but otherwise share no obvious similarity; inactivating apc-2 with RNAi causes embryos to arrest at the meiotic one-cell stage, implying that APC-2 is required for the metaphase-to-anaphase transition of meiosis I; this RNAi phenotype of apc-2 is shared by apc-1, apc-4, apc-11, cdc-16, cdc-23, and cdc-27; by analogy with other APC subunits with hypomorphic alleles, APC-2 is likely to be required for asymmetrical segregation of cell fate determinants in two-cell embryos.
41	bath-3	F59H6.10	n/a	chrII 2,029,895	C. elegans BATH-3 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
42	T07F10.3	T07F10.3	n/a	chrV 12,869,009	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
43	ZK1058.3	ZK1058.3	n/a	chrIII 3,919,762	ZK1058.3 is orthologous to the human gene UNNAMED PROTEIN PRODUCT (GALT; OMIM:606999), which when mutated leads to disease.
44	ZK829.7	ZK829.7	n/a	chrIV 11,960,692	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
45	R05D3.1	R05D3.1	n/a	chrIII 8,384,526	contains similarity to Pfam domains PF00521 (DNA gyrase/topoisomerase IV, subunit A) , PF02518 (Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase) , PF00204 (DNA gyrase B) contains similarity to Interpro domains IPR002205 (DNA topoisomerase, type IIA, subunit A or C-terminal), IPR013506 (DNA topoisomerase, type IIA, subunit B, region 2), IPR001241 (DNA topoisomerase, type IIA, subunit B or N-terminal), IPR011558 (DNA topoisomerase, type IIA, subunit B, conserved region), IPR013758 (DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta), IPR013757 (DNA topoisomerase, type IIA, subunit A, alpha-helical), IPR003594 (ATP-binding region, ATPase-like), IPR013759 (DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta), IPR001154 (DNA topoisomerase II, eukaryotic-type), IPR014721 (Ribosomal protein S5 domain 2-type fold), IPR013760 (DNA topoisomerase, type IIA, central)
46	trm-1	ZC376.5	n/a	chrV 14,184,351	C. elegans TRM-1 protein; contains similarity to Pfam domain PF02005 N2,N2-dimethylguanosine tRNA methyltransferase contains similarity to Interpro domain IPR002905 (N2,N2-dimethylguanosine tRNA methyltransferase)
47	Y116A8C.8	Y116A8C.8	n/a	chrIV 16,932,518	contains similarity to Interpro domain IPR001283 (Allergen V5/Tpx-1 related)
48	F09E5.12	F09E5.12	n/a	chrII 5,368,494	contains similarity to Pfam domain PF05001 RNA polymerase Rpb1 C-terminal repeat
49	dhs-21	R11D1.11	0.000006	chrV 12,732,679	dhs-21 encodes a member of the short-chain dehydrogenases/reductases family (SDR) expressed in the intestine, hypodermis, uterus, and spermatheca.
50	rrt-2	C29H12.1	n/a	chrII 6,126,706	C. elegans RRT-2 protein; contains similarity to Pfam domains PF05746 (DALR anticodon binding domain) , PF00750 (tRNA synthetases class I (R)) contains similarity to Interpro domains IPR015945 (Arginyl-tRNA synthetase, class Ic, core), IPR008909 (DALR anticodon binding), IPR001412 (Aminoacyl-tRNA synthetase, class I, conserved site), IPR009080 (Aminoacyl-tRNA synthetase, class 1a, anticodon-binding), IPR001278 (Arginyl-tRNA synthetase, class Ic), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold)