UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C15B12.3	C15B12.3	2e-51	chrX 6,467,380
2	C50E3.8	C50E3.8	n/a	chrV 7,598,180
3	F11G11.4	F11G11.4	n/a	chrII 4,861,326
4	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
5	rgs-1	C05B5.7	n/a	chrIII 10,015,270	rgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons.
6	C18D1.2	C18D1.2	n/a	chrII 10,057,912	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
7	srf-3	M02B1.1	n/a	chrIV 12,852,213	C. elegans SRF-3 protein; contains similarity to Pfam domains PF08449 (UAA transporter family) , PF04142 (Nucleotide-sugar transporter) contains similarity to Interpro domains IPR004689 (UDP-galactose transporter), IPR013657 (UAA transporter), IPR007271 (Nucleotide-sugar transporter)
8	aqp-6	C32C4.2	n/a	chrV 10,651,251	apq-6 encodes an aquaporin whose expression in Xenopus oocytes increases water permeability five- to seven-fold; aqp-6 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-5; AQP-6 is expressed in the cilia and cell bodies of IL1 sensory neurons; AQP-6 is orthologous to human AQP8 (OMIM:603750).
9	F45E6.3	F45E6.3	n/a	chrX 12,488,021	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
10	C17G1.5	C17G1.5	n/a	chrX 9,943,135	contains similarity to Hepatitis C virus Non-structural protein 5b (Genome polyprotein) (Fragment).; TR:Q8V1C2
11	flp-32	R03A10.2	n/a	chrX 15,434,497	C. elegans FLP-32 protein ;
12	sre-44	W07G1.2	n/a	chrII 13,950,633	C. elegans SRE-44 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
13	F45F2.6	F45F2.6	n/a	chrV 8,527,305	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
14	F56F11.5	F56F11.5	n/a	chrIII 2,853,197
15	lgc-37	ZC482.5	n/a	chrIII 12,789,021	ZC482.5 is orthologous to the human gene GAMMA-AMINOBUTYRIC ACID A RECEPTOR GAMMA 2 (GABRG2; OMIM:137164), which when mutated leads to disease.
16	M05B5.6	M05B5.6	n/a	chrI 7,184,379	contains similarity to Homo sapiens Transient receptor potential cation channel subfamily A member 1; ENSEMBL:ENSP00000262209
17	nhr-167	C49F5.4	n/a	chrX 11,981,020	C. elegans NHR-167 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
18	ttx-3	C40H5.5	n/a	chrX 11,766,841	ttx-3 encodes a LIM homeodomain protein required for functions of the interneuron AIY, including thermosensory behavior and olfactory learning.
19	clec-10	C03H5.1	n/a	chrII 403,400	C. elegans CLEC-10 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
20	npr-3	C10C6.2	n/a	chrIV 11,461,555	C10C6.2 encodes a G-protein-coupled receptor for the FMRFamide-related peptides (FaRPs) encoded by flp-15; C10C6.2 is primarily coupled to Gi/Go proteins, since C10C6.2 signalling is blocked by pertussis toxin; because of its link to Gi/Go proteins, C10C6.2 is expected to be inhibitory
21	adt-1	C02B4.1	n/a	chrX 12,683,974	The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis.
22	Y38H6C.9	Y38H6C.9	n/a	chrV 20,516,299	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
23	F31F4.11	F31F4.11	n/a	chrV 663,441	contains similarity to Pfam domains PF00788 (Ras association (RalGDS/AF-6) domain) , PF02204 (Vacuolar sorting protein 9 (VPS9) domain) contains similarity to Interpro domains IPR013995 (Vacuolar sorting protein 9, subgroup), IPR003123 (Vacuolar sorting protein 9), IPR000159 (Ras-association)
24	W03A5.1	W03A5.1	n/a	chrIII 5,410,601	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR001452 (Src homology-3), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
25	C03C10.7	C03C10.7	n/a	chrIII 4,096,446	contains similarity to Saccharomyces cerevisiae Profilin synthetic lethal protein, has region of coiled-coil structure; subunit of the Exocyst complex--the Exocyst complex contains the gene products encoded by SEC3, SEC5, SEC6, SEC8, SEC10, SEC15 and EXO70 and is required for exocytosis; SGD:YER008C
26	ZK896.1	ZK896.1	n/a	chrIV 12,874,056	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
27	E02H4.4	E02H4.4	n/a	chrX 14,259,690	contains similarity to Arabidopsis thaliana Uncharacterized protein At1g15830.1.; TR:Q3EDB7
28	che-12	B0024.8	n/a	chrV 10,303,399	che-12 encodes a conserved protein that contains at least seven predicted HEAT repeats; CHE-12 activity is required continuously in sensory neurons for formation of distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis to a subset of attractants, including sodium chloride; a che-12::gfp promoter fusion is expressed in the two phasmid neurons and the subset of amphid neurons that contain relatively simple cilia; a CHE-12::GFP protein localizes to cilia in a manner suggesting that it requires intraflagellar transport for proper localization, but is unlikely to be a core IFT particle component; che-12 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor.
29	odr-3	C34D1.3	n/a	chrV 13,248,189	odr-3 encodes a G protein alpha subunit; odr-3 activity is required for normal chemotaxis, odorant avoidance, and nociceptive function as well as cilium morphogenesis in chemosensory neurons; an ODR-3::GFP is expressed in five pairs of sensory neurons AWA, AWB, AWC, ASH, and ADF; the AWC neurons consistently express GFP most strongly, while the AWB neurons express at lower levels and the AWA, ASH, and ADF neurons express only weakly; in AWC neurons, ODR-3::GFP localizes to cilia which have a characteristic wing-shaped morphology.
30	srx-136	F09F3.12	n/a	chrV 13,858,174	C. elegans SRX-136 protein ;
31	F41H8.2	F41H8.2	n/a	chrV 827,588	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
32	F30B5.7	F30B5.7	n/a	chrIV 4,230,520	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
33	moe-3	F32A11.6	n/a	chrII 13,163,070	moe-3 encodes a CCCH tandem zinc finger (TZF) protein; while loss of moe-3 activity via RNAi alone results in no obvious abnormalities, animals triply mutant for moe-3, oma-1, and oma-2 demonstrate oocyte maturation defects, indicating that these genes likely function redundantly during germline development; in situ hybridization experiments indicate that moe-3 mRNA expression is relatively weak and restricted to the distal region of the gonad; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of MOE-3 is predicted to function as an RNA-binding protein.
34	Y12A6A.2	Y12A6A.2	n/a	chrX 13,619,323	contains similarity to Phaseolus lunatus Double-headed bowman-birk inhibitor (Fragment).; TR:Q941H3
35	C03H5.7	C03H5.7	n/a	chrII 381,414	contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR001958 (Tetracycline resistance protein, TetA)
36	F23B2.7	F23B2.7	n/a	chrIV 9,151,248	contains similarity to Homo sapiens similar to Cylicin I (Multiple-band polypeptide I); ENSEMBL:ENSP00000331556
37	F31A9.1	F31A9.1	n/a	chrX 1,797,616
38	F55D12.1	F55D12.1	n/a	chrI 7,884,957	contains similarity to Brachydanio rerio Hypothetical protein.; TR:Q803L4
39	cyp-34A8	B0213.14	n/a	chrV 3,966,310	C. elegans CYP-34A8 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR002397 (Cytochrome P450, B-class), IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
40	F16G10.13	F16G10.13	n/a	chrII 2,395,441	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
41	mab-5	C08C3.3	n/a	chrIII 7,780,108	mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog.
42	C24A11.5	C24A11.5	n/a	chrI 5,385,191
43	str-150	T03E6.4	n/a	chrV 16,584,195	C. elegans STR-150 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	T07D10.1	T07D10.1	n/a	chrI 12,604,999	contains similarity to Strongylocentrotus purpuratus Katanin p80 subunit.; TR:O61585
45	C17H1.6	C17H1.6	n/a	chrI 13,131,624	contains similarity to Danio rerio Arginine and glutamate-rich protein 1-B.; SW:Q6P5L7
46	F15G9.2	F15G9.2	n/a	chrX 9,713,365	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IAW6
47	str-252	C06B3.9	n/a	chrV 13,917,252	C. elegans STR-252 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR008365 (Prostanoid receptor), IPR003002 (7TM chemoreceptor, subfamily 1)
48	T20D4.5	T20D4.5	n/a	chrV 3,414,578	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
49	srh-258	T06E6.7	n/a	chrV 15,405,935	C. elegans SRH-258 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
50	F35E2.1	F35E2.1	n/a	chrI 11,739,734	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR010601 (Protein of unknown function DUF1182)