UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C15A11.4	C15A11.4	0	chrI 7,399,849	contains similarity to Interpro domains IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site), IPR001411 (Tetracycline resistance protein, TetB)
2	T25D1.2	T25D1.2	n/a	chrX 16,516,558	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domains IPR009667 (Protein of unknown function DUF1258), IPR011332 (Ribosomal protein, zinc-binding)
3	srg-69	F09E5.4	n/a	chrII 5,356,499	C. elegans SRG-69 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
4	B0563.8	B0563.8	n/a	chrX 9,174,023
5	T28A11.20	T28A11.20	n/a	chrV 3,272,236	T28A11.20 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T28A11.20 has no clear orthologs in other organisms.
6	fbxb-68	F09C3.3	n/a	chrI 14,286,378	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
7	cids-1	C02F5.4	n/a	chrIII 8,245,008	C. elegans CIDS-1 protein; contains similarity to Pfam domain PF04818 Protein of unknown function, DUF618 contains similarity to Interpro domains IPR006569 (Regulation of nuclear pre-mRNA protein), IPR006903 (Protein of unknown function DUF618), IPR008942 (ENTH/VHS)
8	npp-12	T23H2.1	n/a	chrI 6,450,639	npp-12 encodes Gp210, an evolutionarily conserved membrane protein of the nuclear pore complex (NPC); NPP-12 is required for embryonic viability and normal nuclear membrane structures.
9	F40G12.4	F40G12.4	n/a	chrV 14,268,178	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
10	sre-6	F28H7.9	n/a	chrV 10,761,699	C. elegans SRE-6 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
11	C46F4.1	C46F4.1	n/a	chrX 5,933,527	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
12	D1044.4	D1044.4	n/a	chrIII 5,521,831
13	C13A2.9	C13A2.9	n/a	chrV 7,263,287	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
14	W06A11.2	W06A11.2	n/a	chrII 4,060,321
15	F36F12.8	F36F12.8	n/a	chrV 2,091,148	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
16	srb-1	C27D6.10	n/a	chrII 5,170,361	C. elegans SRB-1 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
17	clec-127	W10G11.5	n/a	chrII 3,568,702	C. elegans CLEC-127 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
18	srt-61	T27C10.1	n/a	chrI 10,905,441	C. elegans SRT-61 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
19	srw-55	T05G11.6	n/a	chrV 15,939,538	C. elegans SRW-55 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
20	T14E8.2	T14E8.2	n/a	chrX 6,542,867	contains similarity to Interpro domain IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
21	ZC404.10	ZC404.10	n/a	chrV 6,801,320	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
22	T27A10.5	T27A10.5	n/a	chrX 3,573,294
23	T23H2.4	T23H2.4	n/a	chrI 6,455,456
24	srw-132	T05B4.5	n/a	chrV 4,107,240	C. elegans SRW-132 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
25	lam-3	T22A3.8	n/a	chrI 10,614,936	lam-3 is orthologous to human LAMININ ALPHA-2 (LAMA2; OMIM:156225), which when mutated leads to merosin-deficient congenital muscular dystrophy.
26	str-18	T23D5.6	n/a	chrV 15,741,213	C. elegans STR-18 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	F26D2.15	F26D2.15	n/a	chrV 16,438,363	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
28	srbc-11	C18B10.1	n/a	chrV 7,494,565	C. elegans SRBC-11 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
29	srw-48	F26D2.9	n/a	chrV 16,421,858	C. elegans SRW-48 protein ; contains similarity to Homo sapiens Uncharacterized protein MPHOSPH1; ENSEMBL:ENSP00000377830
30	age-1	B0334.8	n/a	chrII 11,523,196	age-1 encodes the C. elegans ortholog of the phosphoinositide 3-kinase (PI3K) p110 catalytic subunit; AGE-1, supplied maternally and embryonically, is a central component of the C. elegans insulin-like signaling pathway, lying downstream of the DAF-2/insulin receptor and upstream of both the PDK-1 and AKT-1/AKT-2 kinases and the DAF-16 forkhead type transcription factor, whose negative regulation is the key output of the insulin signaling pathway; in accordance with its role in insulin signaling, AGE-1 activity is required for regulation of metabolism, life span, dauer formation, stress resistance, salt chemotaxis learning, fertility, and embryonic development; although the age-1 expression pattern has not yet been reported, ectopic expression studies indicate that pan-neuronal age-1 expression is sufficient to rescue life-span defects, while neuronal, intestinal, or muscle expression can partially rescue dauer formation, and neuronal or muscle expression can rescue metabolic defects.
31	C47C12.2	C47C12.2	n/a	chrX 7,754,107
32	W03G1.8	W03G1.8	n/a	chrIV 527,981
33	F10A3.7	F10A3.7	n/a	chrV 16,156,140	contains similarity to Pfam domain PF01461 (7TM chemoreceptor)
34	srb-8	F37C12.15	n/a	chrIII 7,172,652	C. elegans SRB-8 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
35	twk-32	F53C11.6	n/a	chrV 13,798,574	C. elegans TWK-32 protein; contains similarity to Pfam domains PF00041 (Fibronectin type III domain) (2), PF07885 (Ion channel) (2)contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR009147 (Cystic fibrosis transmembrane conductance regulator), IPR013099 (Ion transport 2)
36	srsx-11	C13D9.4	n/a	chrV 4,978,533	C. elegans SRSX-11 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
37	F41H8.1	F41H8.1	n/a	chrV 834,574	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
38	K04F1.10	K04F1.10	n/a	chrV 1,663,542	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000494 (EGF receptor, L domain)
39	srb-3	C27D6.8	n/a	chrII 5,166,058	C. elegans SRB-3 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
40	tax-2	F36F2.5	n/a	chrI 9,023,241	tax-2 is orthologous to the human gene ROD PHOTORECEPTOR CNG-CHANNEL BETA SUBUNIT (CNGB1; OMIM:600724), which when mutated leads to disease.
41	H05L14.2	H05L14.2	n/a	chrI 7,987,359	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR000694 (Proline-rich region), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
42	T19H5.2	T19H5.2	n/a	chrII 9,475,595	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001176 (1-aminocyclopropane-1-carboxylate synthase), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
43	R13.2	R13.2	n/a	chrIV 10,826,996	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
44	mnm-2	C10A4.8	n/a	chrX 7,423,795	C. elegans MNM-2 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
45	T24E12.3	T24E12.3	n/a	chrII 3,776,733
46	mes-1	F54F7.5	n/a	chrX 11,859,856	The mes-1 gene encodes a receptor tyrosine kinase-like protein that is required for unequal cell divisions in the early embryonic germline; during embryonic cell divisions, mes-1 is involved in positioning of the early mitotic spindle and of associated P granules.
47	T19D12.7	T19D12.7	n/a	chrII 6,648,354	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
48	C49F5.3	C49F5.3	n/a	chrX 11,983,268	contains similarity to Phytophthora infestans SECY-independent transporter protein.; TR:Q9T238
49	srg-22	Y25C1A.10	n/a	chrII 3,092,472	C. elegans SRG-22 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
50	nhr-219	T19A5.5	n/a	chrV 8,966,534	C. elegans NHR-219 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) (2)contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)