UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	col-35	C15A11.1	6e-45	chrI 7,386,359	col-35 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens; the amino- and carboxyl-terminal cysteine-rich regions of COL-35 are most closely related to those of COL-8, COL-19, and COL-39.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	col-102	C18H7.3	0.00005	chrIV 605,160	col-102 encodes a cuticle collagen.
4	grl-19	R02D3.6	n/a	chrIV 252,252	grl-19 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-19 is expressed in intestine; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
5	F56H9.2	F56H9.2	n/a	chrV 12,637,872	contains similarity to Plasmodium falciparum Transport protein, putative.; TR:Q8IHR3
6	grl-17	C56A3.1	n/a	chrV 13,562,991	grl-17 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-17 is expressed in pharynx, rectal epithelium, amphid socket cells, larval arcade cells, and larval hypodermis; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
7	col-116	F17E9.1	n/a	chrIV 8,357,297	C. elegans COL-116 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
8	F07C4.6	F07C4.6	n/a	chrV 7,627,266	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
9	F57F4.2	F57F4.2	n/a	chrV 6,388,125	contains similarity to Felis silvestris catus RPGR (Fragment).; TR:Q56PC0
10	T20D4.11	T20D4.11	n/a	chrV 3,399,039	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
11	F47B8.8	F47B8.8	n/a	chrV 14,332,167	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domain IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal)
12	clec-60	ZK666.6	n/a	chrII 10,480,905	clec-60 encodes a C-type lectin protein with no obvious non-nematode orthologs required for normal resistance to infection with Microbacterium nematophilum; clec-60 transcription is induced 6.6-fold by infection with M. nematophilum, making it one of the most strongly infection-responsive genes (second only to tts-1), while not being induced by other pathogens; CLEC-60 is expressed throughout the larval intestine, continuing adult expression primarily in the posterior intestinal cells int8 and int9; CLEC-60 contains an N-terminal von Willebrand factor type A domain and a C-terminal C-type lectin domain; CLEC-60 has no obvious function in mass RNAi assays, and is dispensable for viability.
13	hsp-12.3	F38E11.1	n/a	chrIV 9,445,065	hsp-12.3 encodes a small heat-shock protein that forms heterotetramers with HSP-12.2 and has no chaperone-like activity; structurally, HSP-12.3 is mostly a beta-sheet; at least one HSP-12 (which may or may not be HSP-12.2) is ubiquitously expressed in L1 larvae, and later expressed in adult spermatids (and perhaps spermatocytes), and some adult vulval cells; hsp-12.3 is upregulated in daf-2 mutants, suggesting that hsp-12.3's expression may contribute to prolonged lifespan in dauer larvae.
14	T01C3.4	T01C3.4	n/a	chrV 14,994,531	contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
15	F40G12.5	F40G12.5	n/a	chrV 14,269,931	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
16	B0507.8	B0507.8	n/a	chrV 8,761,695	contains similarity to Schizosaccharomyces pombe Nucleoporin nup211 (Nuclear pore protein nup211).; SW:O74424
17	F43H9.4	F43H9.4	n/a	chrV 8,027,713	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
18	nlp-39	C54C8.9	n/a	chrI 12,461,774	C. elegans NLP-39 protein ;
19	nlp-32	F30H5.2	n/a	chrIII 486,349	C. elegans NLP-32 protein; contains similarity to Interpro domain IPR002952 (Eggshell protein)
20	C06G3.3	C06G3.3	n/a	chrIV 7,036,272
21	F11F1.6	F11F1.6	n/a	chrIII 13,403,684	contains similarity to Escherichia coli Shiga toxin 1 B subunit.; TR:Q8L167
22	scl-2	F49E11.10	n/a	chrIV 13,058,350	C. elegans SCL-2 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
23	F22B7.9	F22B7.9	n/a	chrIII 8,653,148
24	clec-97	ZK39.6	n/a	chrI 11,153,502	C. elegans CLEC-97 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
25	col-158	D2023.7	n/a	chrV 11,830,378	C. elegans COL-158 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
26	nlp-28	B0213.3	n/a	chrV 3,988,091	C. elegans NLP-28 protein ; contains similarity to Ixodes scapularis Putative secreted salivary gland peptide.; TR:Q5Q982
27	clec-98	ZK39.7	n/a	chrI 11,154,783	C. elegans CLEC-98 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	col-84	K12D12.3	n/a	chrII 11,869,021	C. elegans COL-84 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
29	F09F7.6	F09F7.6	n/a	chrIII 5,551,674
30	C30F12.3	C30F12.3	n/a	chrI 6,971,092
31	scl-11	F49E11.6	n/a	chrIV 13,051,732	C. elegans SCL-11 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
32	nlp-29	B0213.4	n/a	chrV 3,984,616	nlp-29 encodes a neuropeptide-like protein; nlp-29 appears to play a role in innate immunity, as its expression is strongly induced following bacterial and fungal infection; nlp-29 is expressed in the hypodermis and in the intestine; nlp-29 expression is regulated by TIR-1, an ortholog of SARM, a Toll-interleukin 1 receptor (TIR) domain protein, and by the RAB-1 GTPase and the product of R53.4, a mitochondrial ATP synthase subunit f homolog.
33	C35C5.9	C35C5.9	n/a	chrX 11,536,770	contains similarity to Haemophilus influenzae Monofunctional biosynthetic peptidoglycan transglycosylases(EC 2.4.2.-) (Monofunctional TGase).; SW:MTGA_HAEIN
34	C13A2.3	C13A2.3	n/a	chrV 7,283,523	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
35	C45B2.3	C45B2.3	n/a	chrX 6,083,106
36	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
37	ins-23	M04D8.3	n/a	chrIII 10,028,305	ins-23 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-23 is one of 38 insulin-like peptides in C. elegans, and is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral nerve cord neurons; as loss of INS-23 function via RNA-mediated interference does not results in any abnormalities, the precise role of INS-23 in C. elegans development is not yet clear.
38	C50F4.8	C50F4.8	n/a	chrV 9,518,171
39	nlp-20	F45E4.8	n/a	chrIV 7,642,623	nlp-20 encodes a predicted neuropeptide of the FAFA family; expressed in pharyngeal neurons.
40	col-2	W01B6.7	n/a	chrIV 10,084,918	col-2 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies); expression peaks during the molt that separates the L2 larval and dauer stages as the dauer cuticle is being formed, and mRNA is expressed at low levels in post-dauer L4 larvae and in adult animals.
41	F17C11.4	F17C11.4	n/a	chrV 10,952,702	contains similarity to Mus musculus Desmoglein 2 precursor.; SW:DSG2_MOUSE
42	nlp-12	M01D7.5	n/a	chrI 1,843,618	nlp-12 encodes two predicted neuropeptide-like proteins; nlp-12 is part of a LQFamide neuropeptide family that has members in at least one other nematode species; nlp-12 is expressed in one tail neuron; as loss of nlp-12 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-12-encoded peptides in development and/or behavior is not yet known.
43	C13A2.4	C13A2.4	n/a	chrV 7,279,942	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
44	F49H6.5	F49H6.5	n/a	chrV 17,024,380	The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
45	C32F10.4	C32F10.4	n/a	chrI 5,809,249
46	cpr-2	F36D3.9	n/a	chrV 16,533,516	C. elegans CPR-2 protein; contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
47	W01F3.2	W01F3.2	n/a	chrV 20,656,586	contains similarity to Interpro domain IPR000585 (Hemopexin)
48	cex-1	F56D1.6	n/a	chrII 5,448,034	C. elegans CEX-1 protein; contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
49	col-45	F53G12.7	n/a	chrI 116,588	col-45 encodes a cuticle collagen.
50	col-183	F02D10.1	n/a	chrX 13,467,159	C. elegans COL-183 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)