UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C14C6.5	C14C6.5	3e-95	chrV 537,024	contains similarity to Pfam domains PF04942 (CC domain) , PF01549 (ShK domain-like) (2)contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR003582 (Metridin-like ShK toxin)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C15C8.3	C15C8.3	n/a	chrV 12,743,084	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001461 (Peptidase A1)
4	Y40D12A.2	Y40D12A.2	n/a	chrIII 6,613,768	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
5	gfi-1	F57F4.3	n/a	chrV 6,396,213	gfi-1 encodes a protein that contains 21 ET modules; interacts with unc-68 in yeast two-hybrid assays.
6	F13H6.3	F13H6.3	n/a	chrV 6,364,531	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
7	act-5	T25C8.2	n/a	chrIII 13,605,190	an ortholog of human cytoplasmic actin; and is expressed only in microvillous intestinal cells and excretory cell.
8	ugt-8	H23N18.3	n/a	chrV 4,904,931	C. elegans UGT-8 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
9	Y47H9C.1	Y47H9C.1	n/a	chrI 11,832,085	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
10	T25C12.3	T25C12.3	n/a	chrX 11,495,472	contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR011162 (MHC classes I and II-like antigen recognition), IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR006582 (Region of unknown fuction MD, Caenorhabditis elegans), IPR002035 (von Willebrand factor, type A)
11	T25B6.2	T25B6.2	n/a	chrX 9,036,480	T25B6.2 encodes two isoforms of a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T25B6.2 is orthologous to Ac-mep-1, a gut luminal neprilysin which is specifically expressed in the adult life stage of Ancylostoma caninum hookworms, and whose protein product is localized to the microvilli of the gastrointestinal tract, suggesting a role in digestion.
12	K07C5.4	K07C5.4	n/a	chrV 10,351,696	contains similarity to Pfam domains PF01798 (Putative snoRNA binding domain) , PF08060 (NOSIC (NUC001) domain) , PF08156 (NOP5NT (NUC127) domain) contains similarity to Interpro domains IPR012974 (NOP5, N-terminal), IPR005819 (Histone H5), IPR002687 (Pre-mRNA processing ribonucleoprotein, binding region), IPR012976 (NOSIC)
13	F54F11.2	F54F11.2	n/a	chrII 13,512,057	F54F11.2 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F54F11.2 has no clear orthologs in other organisms.
14	F59A2.3	F59A2.3	n/a	chrIII 3,397,005	contains similarity to Pfam domain PF02330 Mitochondrial glycoprotein contains similarity to Interpro domain IPR003428 (Mitochondrial glycoprotein)
15	R07H5.8	R07H5.8	n/a	chrIV 11,210,138	contains similarity to Pfam domain PF00294 pfkB family carbohydrate kinase contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR002139 (Ribokinase), IPR001805 (Adenosine kinase), IPR002173 (Carbohydrate/puine kinase, PfkB, conserved site)
16	F55G11.2	F55G11.2	n/a	chrIV 12,968,338	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
17	T16G1.6	T16G1.6	n/a	chrV 12,936,341	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
18	spl-1	Y66H1B.4	n/a	chrIV 381,542	C. elegans SPL-1 protein; contains similarity to Pfam domains PF00282 (Pyridoxal-dependent decarboxylase conserved domain) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR002129 (Pyridoxal phosphate-dependent decarboxylase), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
19	C44E4.4	C44E4.4	n/a	chrI 4,634,862	contains similarity to Pfam domains PF05383 (La domain) , PF08777 (RNA binding motif) , PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) contains similarity to Interpro domains IPR002344 (Lupus La protein), IPR014886 (RNA binding motif), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR011991 (Winged helix repressor DNA-binding), IPR006630 (RNA-binding protein Lupus La), IPR000504 (RNA recognition motif, RNP-1)
20	VC5.1	VC5.1	n/a	chrV 7,102,942
21	apy-1	F08C6.6	n/a	chrX 7,568,879	C. elegans APY-1 protein; contains similarity to Pfam domain PF06079 Apyrase contains similarity to Interpro domain IPR009283 (Apyrase)
22	mup-2	T22E5.5	n/a	chrX 6,409,410	mup-2 encodes the muscle contractile protein troponin T ( TnT ) homologous to vertebrate and invertebrate TnT and contains an invertebrate- specific COOH -terminal tail; mup-2 affects embryonic body wall muscle cell contraction, sarcomere organization, cell positioning, regulated muscle contraction in larval and adult body wall muscle, epidermal morphogenesis, and is required for proper function of the hermaphrodite nonstriated oviduct myoepithelial sheath, proper growth, and fertility.
23	gst-5	R03D7.6	n/a	chrII 10,950,899	gst-5 encodes a putative glutathione-S-transferase that inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51.
24	F28A10.6	F28A10.6	n/a	chrII 847,752	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02771 (Acyl-CoA dehydrogenase, N-terminal domain) contains similarity to Interpro domains IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR006089 (Acyl-CoA dehydrogenase, conserved site), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal), IPR006092 (Acyl-CoA dehydrogenase, N-terminal)
25	ZK1025.2	ZK1025.2	n/a	chrI 11,450,904	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
26	F35E12.5	F35E12.5	n/a	chrV 13,737,761	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
27	C26B9.5	C26B9.5	n/a	chrX 5,330,863	contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domain IPR008758 (Peptidase S28)
28	F35D11.4	F35D11.4	n/a	chrII 4,603,738	contains similarity to Pfam domain PF01928 CYTH domain contains similarity to Interpro domains IPR008172 (Adenylate cyclase), IPR008173 (Adenylyl cyclase CyaB)
29	F57F4.4	F57F4.4	n/a	chrV 6,405,140	contains similarity to Pfam domain PF01684 ET module contains similarity to Interpro domains IPR002603 (Protein of unknown function ET), IPR016054 (Ly-6 antigen / uPA receptor -like)
30	clec-52	B0218.8	n/a	chrIV 8,167,950	C. elegans CLEC-52 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR003990 (Pancreatitis-associated protein), IPR001304 (C-type lectin), IPR002352 (Eosinophil major basic protein)
31	eif-3.D	R08D7.3	n/a	chrIII 8,970,522	eif-3.D encodes the C. elegans ortholog of the translation initiation factor 3 subunit d (eIF3d/Moe1); by homology, EIF-3.D is predicted to function as part of the eIF3 translation initiation complex but also as part of a Ras-mediated pathway that regulates mitotic spindle formation; in C. elegans, large-scale RNAi screens indicate that eif-3.D is required for embryonic and germline development, locomotion, and normal rates of post-embryonic growth; in the early embryo, eif-3.D is specifically required for the fidelity of meiotic divisions and normal pseudocleavage; eif-3.D function is likely conserved, as expression of eif-3.D in Schizosaccharomyces pombe can rescue the mitotic spindle and growth defects associated with moe1 mutant cells; to date, eif-3.D expression has been reported in anterior neurons and the pharynx, beginning at late stages of embryogenesis.
32	C18H9.6	C18H9.6	n/a	chrII 6,701,053
33	C16C10.11	C16C10.11	n/a	chrIII 4,152,344	contains similarity to Pfam domain PF06747 CHCH domain contains similarity to Interpro domains IPR010625 (CHCH), IPR000104 (Antifreeze protein, type I), IPR000694 (Proline-rich region)
34	ZC416.6	ZC416.6	n/a	chrIV 3,611,139	n/a
35	Y76A2B.3	Y76A2B.3	n/a	chrIII 13,541,717	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
36	Y49A3A.1	Y49A3A.1	n/a	chrV 14,349,107	Y49A3A.1 encodes a homolog of choline/ethanolaminephosphotransferase choline phosphotransferase 1; Y49A3A.1 shares an operon with vha-13, and thus might be a previously undescribed V-ATPase component or ancillary protein.
37	F58B4.5	F58B4.5	n/a	chrV 10,933,422	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
38	tba-4	F44F4.11	n/a	chrII 10,919,367	tba-4 encodes a member of the alpha tubulin family that also includes tba-1, tba-2, and tba-3, and affects embryonic viability.
39	F01F1.9	F01F1.9	n/a	chrIII 5,862,653	contains similarity to Pfam domain PF02127 Aminopeptidase I zinc metalloprotease (M18) contains similarity to Interpro domain IPR001948 (Peptidase M18, aminopeptidase I)
40	amt-4	C05E11.5	n/a	chrX 4,567,404	amt-4 encodes a member of the ammonium transporter protein family.
41	ugt-13	H23N18.1	n/a	chrV 4,910,117	C. elegans UGT-13 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
42	lec-10	W01A11.4	n/a	chrV 6,488,658	lec-10 encodes a galectin, a soluble galactose-binding lectin; recombinant lec-10 can bind to sugar in an in vitro assay.
43	gst-36	R07B1.4	n/a	chrX 9,862,249	C. elegans GST-36 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR003083 (S-crystallin), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
44	nol-5	W01B11.3	n/a	chrI 3,268,107	C. elegans NOL-5 protein; contains similarity to Pfam domains PF01798 (Putative snoRNA binding domain) , PF08060 (NOSIC (NUC001) domain) , PF08156 (NOP5NT (NUC127) domain) contains similarity to Interpro domains IPR012974 (NOP5, N-terminal), IPR005819 (Histone H5), IPR002687 (Pre-mRNA processing ribonucleoprotein, binding region), IPR012976 (NOSIC)
45	F12A10.7	F12A10.7	n/a	chrII 5,497,776	contains similarity to Interpro domain IPR000817 (Prion protein)
46	dod-19	ZK6.10	n/a	chrV 413,272	C. elegans DOD-19 protein; contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
47	ugt-46	B0310.5	n/a	chrX 528,055	C. elegans UGT-46 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
48	col-149	B0024.1	n/a	chrV 10,292,253	C. elegans COL-149 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
49	K10C2.1	K10C2.1	n/a	chrX 6,425,780	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001563 (Peptidase S10, serine carboxypeptidase)
50	gas-1	K09A9.5	n/a	chrX 15,588,527	The gas-1 gene encodes a 49 kDa subunit of mitochondrial complex I that is required for oxidative phosphorylation, resistance to volatile anesthetics, fecundity, and normal lifespan; gas-1 is expressed in the nematode neuromuscular system; its subcellular distribution appears to be mitochondrial; drug effects on mutants versus wild-type indicate that gas-1 functions at least partially through presynaptic effects; gas-1 mutants have strongly reduced Complex I-dependent metabolism in mitochondria, while Complex II-dependent metabolism is conversely increased in mutants; gas-1 mitochondria look structurally normal.