UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C14B1.5	C14B1.5	0	chrIII 3,708,022	C14B1.5 encodes an ortholog of S. cerevisiae YIL103 and human DPH2L1/OVCA1 (OMIM:603527, deleted or downregulated in ovarian tumors); C14B1.5 is paralogous to S. cerevisiae DPH2/YKL191W, a protein component of diphtamide synthesis; C14B1.5 has no obvious function in mass RNAi assays.
2	M01B2.10	M01B2.10	n/a	chrV 15,261,657	contains similarity to Homo sapiens Phytanoyl-CoA 2-hydroxylase-interacting protein-like; ENSEMBL:ENSP00000362987
3	rpb-12	F23B2.13	n/a	chrIV 9,146,652	C. elegans RPB-12 protein; contains similarity to Pfam domain PF03604 DNA directed RNA polymerase, 7 kDa subunit contains similarity to Interpro domain IPR006591 (RNA polymerase Rbp10)
4	tbx-8	T07C4.2	n/a	chrIII 10,348,548	C. elegans TBX-8 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR000694 (Proline-rich region), IPR001699 (Transcription factor, T-box)
5	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
6	cdh-1	R10F2.1	n/a	chrIII 2,923,253	cdh-1 encodes a cadherin that is similar, in the extracellular domain, to the Drosophila cadherin Dachsous (Ds); although the precise role of cdh-1 in C. elegans development and/or behavior is not yet known, loss of cdh-1 activity via RNAi using the hypersensitive rrf-3 strain can result in locomotion and growth defects, as well as larval lethality.
7	Y37E11B.6	Y37E11B.6	n/a	chrIV 3,598,943	Y37E11B.6 encodes an ortholog of Rpp21 (Rpr2), a protein subunit of the endoribonuclease RNAse P, which cleaves tRNA precursors to produce their mature 5' end.
8	F27D9.3	F27D9.3	n/a	chrX 7,651,282
9	cah-1	F54D8.4	n/a	chrIII 5,084,208	cah-1 encodes a member of the carbonic anhydrase family.
10	srh-8	K09D9.8	n/a	chrV 4,006,527	C. elegans SRH-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR005394 (P2Y12 purinoceptor)
11	lir-3	F37H8.1	n/a	chrII 11,183,865	lir-3 encodes a LIN-26-like zinc-finger protein that shares a unique C2H2 motif together with LIR-1, LIR-2 and LIN-26; as loss of lir-3 activity via mutation or RNAi results in no obvious abnormalities, the precise role of lir-3 in C. elegans development and/or behavior is not yet known.
12	srh-41	Y54G11A.12	n/a	chrII 14,286,480	C. elegans SRH-41 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000264 (Serum albumin), IPR003002 (7TM chemoreceptor, subfamily 1)
13	srd-68	F09C6.7	n/a	chrV 16,901,990	C. elegans SRD-68 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	T08A9.5	T08A9.5	n/a	chrX 7,312,937
15	F29C12.6	F29C12.6	n/a	chrII 13,129,953	contains similarity to Helicobacter pylori Cytotoxicity associated immunodominant antigen (120 kDa protein)s(CAG pathogenicity island protein 26).; SW:CAGA_HELPY
16	srh-270	F37B4.5	n/a	chrV 2,860,866	C. elegans SRH-270 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	F31D5.1	F31D5.1	n/a	chrII 4,220,835	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR003976 (Potassium channel, two pore-domain, TREK), IPR016196 (MFS general substrate transporter)
18	R01H10.5	R01H10.5	n/a	chrIII 10,257,869	contains similarity to Homo sapiens Similar to TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa; ENSEMBL:ENSP00000218510
19	twk-3	M110.2	n/a	chrII 8,211,638	C. elegans TWK-3 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
20	C24A3.1	C24A3.1	n/a	chrX 9,003,584	contains similarity to Aedes aegypti Condensin, SMC5-subunit, putative (Fragment).; TR:Q16IF0
21	K02D7.5	K02D7.5	n/a	chrIV 309,359	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domain IPR004316 (MtN3 and saliva related transmembrane protein)
22	hlh-19	F57C12.3	n/a	chrX 556,516	C. elegans HLH-19 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
23	fbxb-79	R07H5.7	n/a	chrIV 11,189,235	C. elegans FBXB-79 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
24	C25G6.4	C25G6.4	n/a	chrX 1,248,831
25	C02B8.6	C02B8.6	n/a	chrX 8,134,694	contains similarity to Pfam domains PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF02825 (WWE domain) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR004170 (WWE), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
26	ceh-1	F16H11.4	n/a	chrX 4,653,768	ceh-1 encodes a protein that contains a homeobox domain.
27	lin-1	C37F5.1	n/a	chrIV 2,288,106	lin-1 encodes an Ets-domain-containing transcription factor that is a member of the ETS gene family that includes human ELK1, 3, and 4 (OMIM:600247); LIN-1 functions as a general effector of MAP kinase-mediated signaling; when MAP kinase is inactive, LIN-1 forms a complex with LIN-31/WH that inhibits vulval cell fate specification; upon MAP kinase activation (vulval induction), LIN-1 is phosphorylated, dissociates from LIN-31, and becomes inactive, thus allowing for vulval development.
28	C31E10.1	C31E10.1	n/a	chrX 13,985,013	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000238 (Ribosome-binding factor A)
29	nhr-116	F09C6.9	n/a	chrV 16,913,761	C. elegans NHR-116 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	C53C11.1	C53C11.1	n/a	chrX 17,340,978	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
31	K02D7.2	K02D7.2	n/a	chrIV 312,624	K02D7.2 encodes an ortholog of human SNAI2/SLUG (OMIM:602150, mutated in Waardenburg syndrome type IID) and Drosophila ESCARGOT; based on its orthology to SNAI2, K02D7.2 is predicted to be a transcriptional inhibitor.
32	F16B12.5	F16B12.5	n/a	chrX 14,100,488	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
33	str-74	C14H10.4	n/a	chrX 10,240,354	C. elegans STR-74 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	F22F7.6	F22F7.6	n/a	chrV 2,116,951	contains similarity to Homo sapiens N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; ENSEMBL:ENSP00000309096
35	C10E2.4	C10E2.4	n/a	chrX 16,750,349
36	C11D2.2	C11D2.2	n/a	chrIV 6,187,162	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001461 (Peptidase A1)
37	srg-45	C51F7.2	n/a	chrV 12,308,051	C. elegans SRG-45 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
38	tsp-15	F53B6.1	n/a	chrI 8,929,911	C. elegans TSP-15 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
39	nspc-14	F42F12.7	n/a	chrX 12,358,778	C. elegans NSPC-14 protein ;
40	mbr-1	T01C1.2	n/a	chrX 10,720,732	C. elegans MBR-1 protein; contains similarity to Pfam domain PF05225 helix-turn-helix, Psq domain contains similarity to Interpro domains IPR011526 (Helix-turn-helix, Psq-like), IPR007889 (Helix-turn-helix, Psq)
41	K09F5.4	K09F5.4	n/a	chrX 7,710,385
42	C33C12.9	C33C12.9	n/a	chrII 2,188,303	contains similarity to Pfam domain PF05175 Methyltransferase small domain contains similarity to Interpro domains IPR007848 (Methyltransferase small), IPR004557 (Putative methylase), IPR002296 (N6 adenine-specific DNA methyltransferase, N12 class), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
43	F53H4.3	F53H4.3	n/a	chrX 15,886,572	contains similarity to Mus musculus Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).; SW:ATX1_MOUSE
44	F11E6.7	F11E6.7	n/a	chrIV 17,459,510	contains similarity to Trichomonas vaginalis G3 Flocculin, putative.; TR:A2FIF9
45	nlp-13	E03D2.1	n/a	chrV 4,237,211	nlp-13 encodes a predicted neuropeptide of the MSFamide family; expressed primarily in neurons or in the endocrine/secretory cells, and expression includes pharyngeal neurons that modulate pharyngeal pumping of food.
46	Y47H9C.7	Y47H9C.7	n/a	chrI 11,892,653	Y47H9C.7 is orthologous to the human gene EUKARYOTIC TRANSLATION INITIATION FACTOR 2B, SUBUNIT 2 (BETA, 39KD) (EIF2B2; OMIM:606454), which when mutated leads to disease.
47	F29D10.2	F29D10.2	n/a	chrI 8,842,038	contains similarity to Interpro domains IPR000853 (Nematoda metallothionein, family 6), IPR000006 (Metallothionein, vertebrate), IPR002952 (Eggshell protein), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR001396 (Echinodermata metallothionein, family 4), IPR001008 (Mollusc metallothionein, family 2)
48	F30A10.9	F30A10.9	n/a	chrI 9,505,158	contains similarity to Pfam domain PF04900 Fcf1 contains similarity to Interpro domains IPR006984 (Protein of unknown function DUF652), IPR006596 (Nucleotide binding protein, PINc)
49	T07F12.3	T07F12.3	n/a	chrX 4,887,726	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
50	sre-37	F15A4.3	n/a	chrII 12,466,610	C. elegans SRE-37 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)