UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ncx-9	C13D9.8	0	chrV 4,993,269	ncx-9 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6/-8 and NCX-10; NCX-9 may function intracellularly; NCX-9 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-9 has no obvious function in mass RNAi assays.
2	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
3	C13A2.6	C13A2.6	n/a	chrV 7,271,247	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
4	ttr-2	K03H1.4	n/a	chrIII 9,928,259	K03H1.4 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of K03H1.4 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
5	str-182	C12D8.12	n/a	chrV 10,232,595	C. elegans STR-182 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	T26H5.8	T26H5.8	n/a	chrV 15,429,911	contains similarity to Pfam domains PF04789 (Protein of unknown function (DUF621)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR006874 (Protein of unknown function DUF621)
7	C36C5.12	C36C5.12	n/a	chrV 3,158,933	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
8	T04A11.4	T04A11.4	n/a	chrIV 12,483,683	contains similarity to Pfam domain PF02567 Phenazine biosynthesis-like protein contains similarity to Interpro domain IPR003719 (Phenazine biosynthesis PhzC/PhzF protein)
9	ttr-32	R13A5.3	n/a	chrIII 7,566,923	R13A5.3 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; although the product of R13A5.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known, loss of R13A5.3 activity via RNAi has been reported to result in hyperactive locomotion.
10	C03G6.6	C03G6.6	n/a	chrV 7,358,148	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
11	col-114	D2024.8	n/a	chrIV 7,246,056	C. elegans COL-114 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
12	ZC196.2	ZC196.2	n/a	chrV 8,740,693	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
13	D1086.7	D1086.7	n/a	chrV 14,084,866	contains similarity to Synechocystis sp Hypothetical protein slr1028.; TR:P73139
14	F07C4.6	F07C4.6	n/a	chrV 7,627,266	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
15	col-37	ZK863.2	n/a	chrV 12,167,206	col-37 encodes a cuticle collagen.
16	C43F9.4	C43F9.4	n/a	chrIV 10,588,322
17	F48G7.2	F48G7.2	n/a	chrV 637,034
18	ttr-5	C40H1.5	n/a	chrIII 9,330,525	C40H1.5 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of C40H1.5 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
19	F26G1.3	F26G1.3	n/a	chrII 4,759,013	F26G1.3 encodes a protein containing a transthyretin-like domain; the product of F26G1.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
20	fbxa-162	C08E3.5	n/a	chrII 1,608,500	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
21	srbc-20	C45H4.11	n/a	chrV 2,147,858	C. elegans SRBC-20 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
22	rhy-1	W07A12.7	n/a	chrII 9,162,328	C. elegans RHY-1 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
23	F58H7.5	F58H7.5	n/a	chrIV 920,399
24	C32F10.4	C32F10.4	n/a	chrI 5,809,249
25	C13A2.3	C13A2.3	n/a	chrV 7,283,523	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
26	Y37D8A.19	Y37D8A.19	n/a	chrIII 12,930,534	contains similarity to Hordeum vulgare Nonspecific lipid-transfer protein 4.3 precursor (LTP 4.3).; SW:NL43_HORVU
27	C07D10.1	C07D10.1	n/a	chrII 7,399,714	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
28	grl-23	E02A10.2	n/a	chrV 12,576,078	grl-23 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a glycine-rich low-complexity region, a Ground-like (Grl) domain, and an acid-rich low-complexity region; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
29	C06E4.8	C06E4.8	n/a	chrIV 7,284,853	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
30	spp-6	T08A9.10	n/a	chrX 7,317,449	spp-6 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-6 is predicted to function as a lipid-binding protein that may possess pore-forming, cytotoxic activity; as loss of SPP-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of SPP-6 in C. elegans development and/or behavior is not yet known.
31	zig-2	F42F12.2	n/a	chrX 12,340,922	zig-2 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-2::gfp reporter fusion is expressed in the PVT interneuron and weakly in 4-6 additional head neurons.
32	srh-193	F47D2.9	n/a	chrV 4,289,288	C. elegans SRH-193 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	Y57G11C.20	Y57G11C.20	n/a	chrIV 14,844,297	contains similarity to Interpro domain IPR000003 ()
34	W01F3.2	W01F3.2	n/a	chrV 20,656,586	contains similarity to Interpro domain IPR000585 (Hemopexin)
35	W07B8.4	W07B8.4	n/a	chrV 1,131,011	contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
36	W02D7.8	W02D7.8	n/a	chrV 8,305,769
37	C08F11.3	C08F11.3	n/a	chrIV 13,620,866	contains similarity to Homo sapiens HOR5'Beta8; ENSEMBL:ENSP00000332473
38	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
39	F31E3.6	F31E3.6	n/a	chrIII 6,982,722
40	F17C11.4	F17C11.4	n/a	chrV 10,952,702	contains similarity to Mus musculus Desmoglein 2 precursor.; SW:DSG2_MOUSE
41	F43H9.4	F43H9.4	n/a	chrV 8,027,713	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
42	fbxa-69	F54B8.3	n/a	chrV 15,815,021	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
43	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
44	skr-5	F47H4.10	n/a	chrV 17,348,283	The skr-5 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-5(RNAi) animals are at least superficially normal.
45	Y106G6D.6	Y106G6D.6	n/a	chrI 10,120,080	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
46	C31B8.4	C31B8.4	n/a	chrV 2,897,526	contains similarity to Homo sapiens cDNA FLJ77065, highly similar to Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA; ENSEMBL:ENSP00000349305
47	F49H6.5	F49H6.5	n/a	chrV 17,024,380	The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
48	grl-3	K03B8.7	n/a	chrV 11,411,850	grl-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-3 is expressed in intestine, larval renal gland cells, and larval neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
49	W03F11.1	W03F11.1	n/a	chrI 2,220,892	W03F11.1 encodes a protein with three chitin-binding peritrophin-A domains; like CEJ-1 and CPG-2, W03F11.1 may participate in eggshell synthesis and early embryonic development; W03F11.1 is required for fertility in mass RNAi assays; W03F11.1's multiple peritrophin-A domains might enable mechanical cross-linking of chitin.
50	acl-1	F59F4.4	n/a	chrX 15,850,758	acl-1 encodes a 1-acyl-sn-glycerol-3-phosphate acyltransferase; ACL-1 is predicted to be a membrane protein that plays a role in phospholipid biosynthesis, but as loss of acl-1 activity via large-scale RNAi experiments results in no obvious defects, the precise role of ACL-1 in C. elegans development and/or behavior is not yet known.