UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cal-1	C13C12.1	3e-123	chrV 12,515,481	cal-1 encodes one of five predicted C. elegans calcium-binding calmodulin homologs (the others being CAL-2, CAL-3, CAL-4, and CMD-1); as loss of cal-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CAL-1 in C. elegans development and/or behavior is not yet known.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	K09H11.6	K09H11.6	n/a	chrV 5,735,411
4	C17B7.2	C17B7.2	n/a	chrV 3,349,796	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
5	nhr-19	E02H1.7	n/a	chrII 9,601,747	C. elegans NHR-19 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
6	M03E7.1	M03E7.1	n/a	chrV 5,624,123	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
7	C15B12.4	C15B12.4	n/a	chrX 6,472,014	contains similarity to Interpro domain IPR000158 (Cell division protein FtsZ, N-terminal)
8	pqn-48	K07D4.8	n/a	chrII 4,040,965	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
9	rcn-1	F54E7.7	n/a	chrIII 5,683,173	rcn-1 encodes a calcipressin, which binds and inhibits calcineurin; RCN-1's orthologs include yeast Rcn1p and human DSCR1 (OMIM:602917; overexpressed in Down syndrome and Alzheimer disease); rcn-1 is expressed in hypodermal seam cells, various neurons, vulval epithelial and muscle cells, marginal pharyngeal cells, and in the male tail; rcn-1 transcription is regulated by TAX-6, and RCN-1 binds TAX-6 protein if free Ca[2+] is present; RCN-1 overexpression, like calcineurin deficiency, causes defects in body size, cuticle thickness, fertility, growth rate, and serotonin-resistance in egg-laying.
10	ttr-24	Y51A2D.9	n/a	chrV 18,555,981	C. elegans TTR-24 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
11	F37C4.8	F37C4.8	n/a	chrIV 3,880,246
12	C55H1.1	C55H1.1	n/a	chrV 6,851,202	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
13	F25E5.4	F25E5.4	n/a	chrV 7,450,232	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
14	R07A4.4	R07A4.4	n/a	chrX 10,753,200	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR008266 (Tyrosine protein kinase, active site)
15	F21D12.5	F21D12.5	n/a	chrII 7,329,535	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
16	R07C12.3	R07C12.3	n/a	chrIV 4,145,897
17	T08G5.2	T08G5.2	n/a	chrV 14,025,155	contains similarity to Homo sapiens Galactoside 2-alpha-L-fucosyltransferase 1; ENSEMBL:ENSP00000312021
18	H32K16.1	H32K16.1	n/a	chrI 9,151,388	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domain IPR013057 (Amino acid transporter, transmembrane)
19	B0507.2	B0507.2	n/a	chrV 8,775,382	contains similarity to Interpro domain IPR004328 (BRO1)
20	T22B2.1	T22B2.1	n/a	chrX 3,927,779	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
21	twk-9	ZK1251.8	n/a	chrIV 9,695,064	C. elegans TWK-9 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
22	ins-4	ZK75.1	n/a	chrII 5,996,546	ins-4 encodes an insulin-like peptide.
23	F19B10.3	F19B10.3	n/a	chrII 3,664,939
24	hgo-1	W06D4.1	n/a	chrI 9,052,445	hgo-1 encodes a putative homogentisate 1,2-dioxygenase, orthologous to human HGD (OMIM:607474, mutated in alkaptonuria), that is required for normal resistance to hypertonic stress; HGO-1 is expressed in larval and adult hypodermis and intestine, and in larval pharynx; HGO-1 is required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
25	C49C8.2	C49C8.2	n/a	chrIV 8,651,405
26	unc-46	C04F5.3	n/a	chrV 5,098,120	unc-46 encodes a novel protein with a single predicted transmembrane domain; UNC-46 and UNC-47, a novel transmembrane vesicular GABA transporter, are required in GABAergic neurons for all GABA neurotransmission, specifically for loading of GABA into synaptic vesicles, where UNC-46 is localized; UNC-46 localization requires UNC-47, which when overexpressed can rescue unc-46 mutant animals.
27	F49C12.6	F49C12.6	n/a	chrIV 9,308,209	contains similarity to Pfam domains PF06800 (Sugar transport protein) , PF07857 (CEO family (DUF1632)) contains similarity to Interpro domains IPR012435 (Protein of unknown function DUF1632), IPR010651 (Sugar transport), IPR005384 (Duffy antigen/chemokine receptor)
28	Y37D8A.6	Y37D8A.6	n/a	chrIII 12,857,304	contains similarity to Interpro domains IPR006629 (LPS-induced tumor necrosis factor alpha factor), IPR013032 (EGF-like region, conserved site)
29	F54B8.4	F54B8.4	n/a	chrV 15,816,808	The F54B8.4 gene encodes a homolog of Death Associated Protein 1 (DAP-1) protein that may be involved in apoptosis.
30	F41E7.7	F41E7.7	n/a	chrX 10,311,728	contains similarity to Drosophila grimshawi Chorion protein S18.; SW:CH18_DROGR
31	T23B3.1	T23B3.1	n/a	chrI 6,718,630
32	F40G9.8	F40G9.8	n/a	chrIII 164,235
33	T27F2.4	T27F2.4	n/a	chrV 11,650,405	contains similarity to Interpro domain IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
34	ZC204.1	ZC204.1	n/a	chrII 1,666,906	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
35	Y6G8.2	Y6G8.2	n/a	chrV 17,596,508	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
36	R13H4.5	R13H4.5	n/a	chrV 11,861,454	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
37	C30B5.7	C30B5.7	n/a	chrII 6,225,999	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR003944 (Protease-activated receptor 4)
38	fbxa-195	R09B5.1	n/a	chrV 1,435,696	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
39	F02C12.2	F02C12.2	n/a	chrX 13,398,638	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
40	snb-2	F23H12.1	n/a	chrV 12,345,050	C. elegans SNB-2 protein; contains similarity to Pfam domain PF00957 Synaptobrevin contains similarity to Interpro domains IPR016444 (Synaptobrevin, metazoa/fungi), IPR001388 (Synaptobrevin)
41	K12H6.10	K12H6.10	n/a	chrII 2,822,965
42	C24D10.8	C24D10.8	n/a	chrIV 5,165,608	n/a
43	C50A2.3	C50A2.3	n/a	chrIV 1,148,209
44	B0524.5	B0524.5	n/a	chrIII 1,892,549	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
45	acr-15	F25G6.4	n/a	chrV 8,554,009	A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
46	W02D9.10	W02D9.10	n/a	chrI 12,551,930
47	R102.3	R102.3	n/a	chrIV 10,691,049	contains similarity to Broad bean wilt virus 2 210kDa protein.; TR:Q9E933
48	F23F1.7	F23F1.7	n/a	chrII 39,046	contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)
49	pah-1	K08F8.4	n/a	chrII 8,763,866	pah-1 encodes a biochemically active phenylalanine-4-hydroxylase orthologous to human PAH (OMIM:261600, mutated in phenylketonuria); recombinant PAH-1 has hydroxylase activity on phenylalanine and tryptophan substrates in vitro; pah-1 is expressed in seam cells, tail hypodermal cells, and ventral hypodermis, with stronger posterior than anterior expression; PAH-1 might help provide tyrosine for cross-linking in the cuticle, and is partially required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
50	srv-10	F53F1.9	n/a	chrV 13,424,568	C. elegans SRV-10 protein; contains similarity to Interpro domain IPR001411 (Tetracycline resistance protein, TetB)