UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C12D12.3	C12D12.3	5.0000000000000004e-82	chrX 3,490,216
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	K11E4.3	K11E4.3	n/a	chrX 13,721,488	The K11E4.3 gene encodes one of five paraoxonase-like proteins; it is homologous to the human PARAOXONASE 1 gene (PON1, OMIM:168820), which in some allelic forms is associated with susceptibility to coronary artery disease.
4	srh-251	R08H2.4	n/a	chrV 15,379,118	C. elegans SRH-251 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	ceh-7	C34C6.8	n/a	chrII 8,703,530	ceh-7 encodes a homeodomain transcription factor; expressed in cells around the rectum of the male tail.
6	srh-300	Y94A7B.6	n/a	chrV 17,822,964	C. elegans SRH-300 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	C55C3.2	C55C3.2	n/a	chrIV 5,707,741
8	F22F7.3	F22F7.3	n/a	chrV 2,113,100	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
9	R03A10.1	R03A10.1	n/a	chrX 15,430,484	contains similarity to Saccharomyces cerevisiae Protein involved in transcription-coupled repair nucleotide exicision repair of UV-induced DNA lesions; homolog of human CSB protein; SGD:YJR035W
10	ace-4	Y48B6A.7	n/a	chrII 14,201,652	ace-4 encodes an divergent acetylcholinesterase homolog with biochemically undetectable activity.
11	hot-5	K07A12.6	n/a	chrI 8,685,157	hot-5 encodes a predicted membrane-associated protein that is a member of the Ly-6 superfamily of glycosylphosphatidylinositol (GPI)-linked signaling proteins and is homologous to ODR-2, a neuronally expressed protein required for olfaction; as loss of hot-5 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HOT-5 in C. elegans development and/or behavior is not yet known.
12	B0250.9	B0250.9	n/a	chrV 20,478,476	B0250.9 is orthologous to the human gene 7-DEHYDROCHOLESTEROL REDUCTASE (DHCR7; OMIM:602858), which when mutated leads to disease.
13	ceh-16	C13G5.1	n/a	chrIII 8,624,237	ceh-16 encodes a homeodomain protein orthologous to Drosophila and vertebrate Engrailed proteins involved in segment and appendage development; ceh-16 is an essential gene required for proper specification and differentiation of the lateral seam cells during embryonic development; in specifying seam cell fates, CEH-16 appears to act as a transcriptional regulator, repressing expression of the eff-1 gene required for cell fusion and inducing expression of seam cell-specific genes such as elt-5/GATA, nhr-73, and nhr-74; a rescuing CEH-16::GFP fusion protein is first expressed in the early embryo in cells of the AB lineage; in later embryonic stages CEH-16::GFP is seen in all lateral seam cell nuclei as well as in some anterior neurons; during postembryonic development, CEH-16::GFP is expressed in the DA1 and DD1 motorneurons.
14	mab-5	C08C3.3	n/a	chrIII 7,780,108	mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog.
15	gpa-10	C55H1.2	n/a	chrV 6,853,746	gpa-10 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASI, ASJ, ALN, CAN, LUA, and the spermatheca.
16	R07C3.14	R07C3.14	n/a	chrII 929,840
17	C24A11.5	C24A11.5	n/a	chrI 5,385,191
18	fbxb-53	F36H5.5	n/a	chrII 1,759,512	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
19	srx-85	F38B7.4	n/a	chrV 11,553,428	C. elegans SRX-85 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
20	nhr-44	T19A5.4	n/a	chrV 8,962,974	C. elegans NHR-44 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
21	F59C6.8	F59C6.8	n/a	chrI 10,511,155	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
22	srx-98	F19B10.8	n/a	chrII 3,670,182	C. elegans SRX-98 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
23	F58G1.7	F58G1.7	n/a	chrII 12,945,904	contains similarity to Interpro domain IPR008075 (Lipocalin-1 receptor)
24	C15H9.4	C15H9.4	n/a	chrX 6,103,253	contains similarity to Danio rerio Novel protein similar to human cerebral protein 11 (HUCEP11).; TR:Q1MTK0
25	F08B4.4	F08B4.4	n/a	chrIV 8,679,036
26	rab-28	Y11D7A.4	n/a	chrIV 9,243,090	rab-28 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; the precise biological role and expression pattern of rab-28 are not yet known.
27	F59D6.1	F59D6.1	n/a	chrV 3,051,786
28	B0207.2	B0207.2	n/a	chrI 5,955,959
29	M03B6.4	M03B6.4	n/a	chrX 13,859,911	contains similarity to Halobacterium sp Vng0659h.; TR:Q9HRK3
30	T01C8.4	T01C8.4	n/a	chrX 16,788,345	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR004838 (Aminotransferases, class-I, pyridoxal-phosphate-binding site), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
31	F45E6.3	F45E6.3	n/a	chrX 12,488,021	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
32	acr-12	R01E6.4	n/a	chrX 13,534,608	acr-12 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8-like group of C. elegans nAChR subunits; as an nAChR subunit, ACR-12 is predicted to mediate fast excitatory neurotransmission, however loss of acr-12 activity via mutation or RNAi results in no obvious defects; ACR-12 copurifies with UNC-29 and LEV-1, suggesting that ACR-12 can form receptors with these two non-alpha AChR subunits; an ACR-12::GFP fusion protein is expressed exclusively in ventral cord motor neurons, including the D neurons; in vivo, ACR-12 colocalizes with some, but not all, UNC-38-containing postsynaptic receptor clusters, suggesting that ACR-12 contributes to only a subset of these receptor clusters.
33	K02E10.6	K02E10.6	n/a	chrX 2,481,834	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
34	F16G10.6	F16G10.6	n/a	chrII 2,377,526	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
35	K09H11.6	K09H11.6	n/a	chrV 5,735,411
36	sas-6	Y45F10D.9	n/a	chrIV 13,787,798	sas-6 encodes a protein that contains a coiled-coil region and a novel PISA (present in SAS-6) motif which is conserved in similar proteins in at least eight other species that contain basal bodies or centrioles; SAS-6 activity, along with that of ZYG-1, SAS-4, SAS-5, and SPD-2, is essential for centriole duplication; SAS-6 functions in a dose-dependent manner and localizes to centriolar cylinders; SAS-6 co-localizes to centrioles with SAS-4 and SAS-5, and is mutually dependent upon SAS-5, with which it interacts physically, for centriolar localization; SAS-6 localization also requires the activity of the ZYG-1 kinase; in addition to the early embryo, SAS-6 is also detected in sperm.
37	srz-48	F20E11.1	n/a	chrV 17,459,315	C. elegans SRZ-48 protein ;
38	ZK816.1	ZK816.1	n/a	chrX 3,359,733
39	unc-3	Y16B4A.1	n/a	chrX 14,778,472	The unc-3 gene encodes a protein with homology to immunoglobulin (Ig) domain-containing transcription factors such as OLF-1 or SU(H).
40	F41H8.2	F41H8.2	n/a	chrV 827,588	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
41	Y44A6B.3	Y44A6B.3	n/a	chrV 20,633,182	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
42	B0563.7	B0563.7	n/a	chrX 9,153,274	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000261 (EPS15 homology (EH))
43	B0302.2	B0302.2	n/a	chrX 17,178,681
44	T21D12.7	T21D12.7	n/a	chrIV 290,077	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR013090 (Phospholipase A2, active site), IPR006150 (Cysteine-rich repeat)
45	srh-80	DC2.1	n/a	chrV 221,355	C. elegans SRH-80 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	T07D10.1	T07D10.1	n/a	chrI 12,604,999	contains similarity to Strongylocentrotus purpuratus Katanin p80 subunit.; TR:O61585
47	F47G4.6	F47G4.6	n/a	chrI 14,060,105	contains similarity to Pfam domain PF00505 HMG (high mobility group) box contains similarity to Interpro domains IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG)
48	W03A5.1	W03A5.1	n/a	chrIII 5,410,601	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR001452 (Src homology-3), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
49	C16D9.3	C16D9.3	n/a	chrV 8,239,232
50	C06B3.1	C06B3.1	n/a	chrV 13,903,319	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR008365 (Prostanoid receptor), IPR003002 (7TM chemoreceptor, subfamily 1)