UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	taf-3	C11G6.1	0	chrX 16,334,113	taf-3 encodes the C. elegans ortholog of mammalian TAF3(TAFII140), a component of the RNA polymerase II TFIID transcription complex; TAF-3 contains a histone fold-like domain in its N-terminus and by homology, is predicted to function in transcriptional regulation; however, as loss of taf-3 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of taf-3 in C. elegans development and/or behavior is not yet known.
2	sri-70	Y61B8B.1	n/a	chrV 17,303,714	C. elegans SRI-70 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000883 (Cytochrome c oxidase, subunit I)
3	W03G1.4	W03G1.4	n/a	chrIV 509,467	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
4	skr-16	C42D4.6	n/a	chrIV 7,169,011	The skr-16 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-16(RNAi) animals are at least superficially normal.
5	C53D6.6	C53D6.6	n/a	chrIV 9,030,151	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
6	glb-20	R01E6.6	n/a	chrX 13,554,276	glb-20 encodes a globin; glb-20 transcription is higher in L3 and dauers than in young adults; glb-20 has no obvious function in mass RNAi assays.
7	B0304.2	B0304.2	n/a	chrII 4,524,073
8	F39G3.6	F39G3.6	n/a	chrV 4,712,695	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
9	sqv-8	ZK1307.5	n/a	chrII 9,648,550	The sqv-8 gene encodes a glucuronyl transferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-8 is homologous to three distinct glucuronyl transferases (GlcAT-I, GlcAT-P and GlcAT-D) that play a role in the synthesis of different glycoconjugates; the common requirement for SQV-8 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
10	W03F9.1	W03F9.1	n/a	chrV 125,395	contains similarity to Pfam domain PF03367 ZPR1 zinc-finger domain contains similarity to Interpro domain IPR004457 (Zinc finger, ZPR1-type)
11	F07G6.3	F07G6.3	n/a	chrX 1,723,986
12	W01A11.2	W01A11.2	n/a	chrV 6,497,783	contains similarity to Pfam domain PF03982 Diacylglycerol acyltransferase contains similarity to Interpro domain IPR007130 (Diacylglycerol acyltransferase)
13	Y51B9A.8	Y51B9A.8	n/a	chrII 9,399,270	contains similarity to Pfam domains PF04942 (CC domain) (2), PF01549 (ShK domain-like) contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR003582 (Metridin-like ShK toxin)
14	ZK1307.9	ZK1307.9	n/a	chrII 9,650,113	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
15	C08A9.8	C08A9.8	n/a	chrX 17,103,774	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
16	fbxb-21	ZC204.8	n/a	chrII 1,648,389	fbxb-21 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-21 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
17	K08F9.1	K08F9.1	n/a	chrV 15,138,399	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
18	F59B10.2	F59B10.2	n/a	chrII 10,508,511	contains similarity to Interpro domains IPR003993 (Treacher Collins syndrome, treacle), IPR005819 (Histone H5)
19	srab-20	T20D4.1	n/a	chrV 3,429,701	C. elegans SRAB-20 protein; contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
20	B0564.4	B0564.4	n/a	chrIV 13,112,036	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
21	str-116	F07B10.2	n/a	chrV 11,267,629	C. elegans STR-116 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	acbp-5	T12D8.3	n/a	chrIII 13,640,695	C. elegans ACBP-5 protein; contains similarity to Pfam domains PF00023 (Ankyrin repeat) (2), PF00887 (Acyl CoA binding protein) contains similarity to Interpro domains IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR002110 (Ankyrin), IPR000582 (Acyl-CoA-binding protein, ACBP)
23	scl-19	ZK384.1	n/a	chrV 18,732,354	C. elegans SCL-19 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
24	F01F1.14	F01F1.14	n/a	chrIII 5,882,603
25	T09E11.10	T09E11.10	n/a	chrI 12,346,532	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
26	sri-77	D2062.9	n/a	chrII 2,604,314	C. elegans SRI-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	K08D9.1	K08D9.1	n/a	chrV 3,236,735
28	R03D7.2	R03D7.2	n/a	chrII 10,933,886	contains similarity to Rhodopirellula baltica DNA-binding protein SMUBP-2.; TR:Q7UWP1
29	C56C10.10	C56C10.10	n/a	chrII 6,593,325	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) , PF00515 (Tetratricopeptide repeat) contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
30	K01A2.6	K01A2.6	n/a	chrII 300,268
31	Y38H8A.5	Y38H8A.5	n/a	chrIV 13,467,731	The Y38H8A.5 gene encodes a homolog of the human gene ZNF195 (or p57KIP2), which when mutated leads to Beckwith-Wiedemann syndrome (OMIM:130650).
32	T10H10.2	T10H10.2	n/a	chrX 2,296,444	contains similarity to Pfam domains PF04777 (Erv1 / Alr family) , PF00085 (Thioredoxin) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR006863 (Erv1/Alr), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related)
33	ZK686.1	ZK686.1	n/a	chrIII 7,773,406	contains similarity to Interpro domain IPR004038 (Ribosomal protein L7Ae/L30e/S12e/Gadd45)
34	mom-4	F52F12.3	n/a	chrI 9,898,245	mom-4 encodes a MAP kinase kinase kinase-related protein orthologous to Drosophila Tak1 and the vertebrate MAPKKK7 proteins; during embryonic development, mom-4 activity is required for positive regulation of the Wnt pathway signaling that governs anterior/posterior (A/P) polarity: MOM-4 stimulates the WRM-1/LIT-1-dependent phosphorylation of POP-1, a TCF/LEF-related transcription factor, leading to its downregulation in posterior daughters of A/P cell divisions.
35	F25H9.7	F25H9.7	n/a	chrV 13,468,733	contains similarity to Pfam domain PF05882 ACN9 family contains similarity to Interpro domain IPR008381 (ACN9)
36	F35H10.5	F35H10.5	n/a	chrIV 8,300,920
37	ZK1248.13	ZK1248.13	n/a	chrII 5,830,927
38	C10G11.6	C10G11.6	n/a	chrI 6,291,932
39	C33A12.12	C33A12.12	n/a	chrIV 9,483,553	contains similarity to Interpro domains IPR000225 (Armadillo), IPR016024 (Armadillo-type fold)
40	F35E8.9	F35E8.9	n/a	chrV 15,916,920	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
41	F38E1.11	F38E1.11	n/a	chrV 8,379,393
42	sqv-7	C52E12.3	n/a	chrII 7,011,690	The sqv-7 gene encodes a nucleotide-sugar transporter of the Golgi membrane, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-7 promotes glycosaminoglycan biosynthesis by translocating UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-galactose into the lumen of the Golgi apparatus; SQV-7 is biochemically active when transgenically expressed in yeast or mammalian Golgi membranes; the common requirement for SQV-7 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
43	T15D6.8	T15D6.8	n/a	chrI 12,390,358	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
44	F46B3.15	F46B3.15	n/a	chrV 20,628,725	contains similarity to Interpro domain IPR003645 (Follistatin-like, N-terminal)
45	arx-2	K07C5.1	n/a	chrV 10,336,882	arx-2 encodes the C. elegans ortholog of the Arp2 subunit of the actin-related protein (Arp)2/3 complex.
46	srt-45	M162.3	n/a	chrV 19,780,434	C. elegans SRT-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	srd-25	F07C4.4	n/a	chrV 7,632,583	C. elegans SRD-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	W06B4.1	W06B4.1	n/a	chrII 4,472,468
49	flh-2	C26E6.2	n/a	chrIII 4,953,580	C. elegans FLH-2 protein; contains similarity to Pfam domain PF04500 FLYWCH zinc finger domain contains similarity to Interpro domain IPR007588 (Zinc finger, FLYWCH-type)
50	F53H2.1	F53H2.1	n/a	chrV 20,385,929	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR007883 (Protein of unknown function DUF713)