UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C11E4.7	C11E4.7	0	chrX 9,617,962
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C06A5.1	C06A5.1	n/a	chrI 6,017,022	contains similarity to Drosophila melanogaster Flybase gene name is CG3173-PA;; FLYBASE:CG3173
4	T01B11.1	T01B11.1	n/a	chrIV 8,448,108	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
5	F43H9.3	F43H9.3	n/a	chrV 8,024,072	contains similarity to Homo sapiens PAP associated domain containing 4; ENSEMBL:ENSP00000296783
6	H28G03.4	H28G03.4	n/a	chrX 5,223,420	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
7	fem-2	T19C3.8	n/a	chrIII 633,323	A CB5161 ortholog of fem-2, Cbn-fem-2, has been isolated from the sibling Caenorhabditis species CB5161.
8	T12A2.6	T12A2.6	n/a	chrIII 6,243,060
9	sri-63	F39E9.3	n/a	chrII 3,288,198	C. elegans SRI-63 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003544 (Cytochrome c-type biogenesis protein CcmB)
10	srxa-10	R10E11.7	n/a	chrIII 9,795,820	C. elegans SRXA-10 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
11	srw-118	C44C3.5	n/a	chrV 2,979,418	C. elegans SRW-118 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
12	inx-7	K02B2.4	n/a	chrIV 5,945,314	C. elegans INX-7 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
13	odr-7	T18D3.2	n/a	chrX 12,460,277	odr-7 encodes an olfactory-specific member of the nuclear receptor superfamily that affects chemotaxis to some volatile odorants and the cell fate of the AWA olfactory neurons; ODR-7 is expressed in the AWA neurons; in specifying the identity of the AWA neurons, ODR-7 appears to lie upstream of odr-10, which encodes a seven transmembrane domain olfactory receptor that is required for the response to diacetyl, an odorant detected by the AWA neurons.
14	mes-2	R06A4.7	n/a	chrII 14,386,115	mes-2 encodes a SET domain-containing protein that is orthologous to the Drosophila Polycomb group protein Enhancer of zeste [E(Z)]; as a member of a Polycomb-like chromatin repressive complex with MES-3 and MES-6, MES-2 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; in addition, MES-2 activity is required for normal levels and localization of MES-3 in >24-cell-stage embryos; MES-2 expression is detected in the primordial germ cells and germline nuclei throughout development, in all nuclei in early embryos, and in somatic nuclei, including those of the male tail, in L2 and L3 larvae; in the nucleus, MES-2 appears to localize to chromatin.
15	thoc-2	C16A3.8	n/a	chrIII 6,370,914	C. elegans THOC-2 protein ; contains similarity to Homo sapiens THO complex 2 isoform 1; ENSEMBL:ENSP00000347959
16	F25B4.4	F25B4.4	n/a	chrV 5,685,274
17	rheb-1	F54C8.5	n/a	chrIII 9,455,024	rheb-1 encodes a GTPase orthologous to the mammalian Rheb and Rheb1 GTPases; loss of rheb-1 activity via RNAi indicates that RHEB-1 is involved in the mitochondrial unfolded protein response and that its function is required for normal growth rates, body size, osmoregulation, reproduction, and locomotion.
18	dyrb-1	T24H10.6	n/a	chrII 9,106,748	dyrb-1 encodes a small (95-residue) putative cytoplasmic dynein light chain 2A that inhibits DHC-1 in vivo, and is also required for mitotic spindle positioning, embryonic viability and fertility; DYRB-1 is orthologous to Drosophila ROADBLOCK (and six Drosophila paralogs), Chlamydomonas LC7, human DYNLRB1 (OMIM:607167), and human DYNLRB2 (OMIM:607168); dyrb-1(RNAi) and dyrb-1(tm2645) both suppress the lethality of conditional dhc-1 mutations, and dyrb-1(RNAi) suppresses dhc-1(or195) spindle length and cytokinesis defects as well, indicating that DYRB-1 negatively regulates dynein; in oocytes and early embryos, DYRB-1 is associated with nuclear envelopes and centrosomes, and with meiotic and mitotic spindle poles; like DHC-1 itself, DYRB-1 is strongly mislocalized to centrosomes in dhc-1(or195) animals shifted to nonpermissive temperature.
19	srj-4	C27A7.7	n/a	chrV 12,163,847	C. elegans SRJ-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	pes-7	F09C3.1	n/a	chrI 14,267,298	pes-7 encodes an IQGAP ortholog; IQGAP proteins bind actin and CLIP-170, effect activities of the Rho family GTPases Rac1 and Cdc42, and function in cytokinesis; PES-7 is required for completing meiosis and mitosis, and for germline formation and maintenance; IQGAP's alpha-actinin domain is related distantly to alpha-actinin domains in calponin, transgelin (SM22 alpha), and the proto-oncogene Vav; a pes-7 reporter is first expressed in the ventral nerve cord of the elongating embryo and in later stages of development is also expressed in all major ganglia, the vulva, and in the spermathecal valves; in the ventral nerve cord, pes-7 expression is detected in nuclei as well as in cell bodies and neural processes.
21	C04C3.4	C04C3.4	n/a	chrIV 3,394,502
22	F43D2.3	F43D2.3	n/a	chrV 14,632,476	contains similarity to Homo sapiens Orphan nuclear receptor NR1D1; ENSEMBL:ENSP00000246672
23	ZC196.4	ZC196.4	n/a	chrV 8,734,518	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domains IPR007883 (Protein of unknown function DUF713), IPR000565 (DNA topoisomerase, type IIA, subunit B)
24	coh-3	F08H9.1	n/a	chrV 14,458,664	coh-3 encodes a member of the Rad21/Rec8-like family of cohesion proteins that is expressed in the germline; an effect on embryonic viability has been reported based on some RNAi screens, but has not been demonstrated in others.
25	srbc-67	T24A6.10	n/a	chrV 3,539,627	C. elegans SRBC-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
26	F52C12.3	F52C12.3	n/a	chrIV 1,950,714
27	C07A4.1	C07A4.1	n/a	chrX 10,169,900	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
28	F17B5.2	F17B5.2	n/a	chrI 13,192,171	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
29	F59H6.3	F59H6.3	n/a	chrII 2,018,441
30	str-165	F55B12.6	n/a	chrV 13,832,194	C. elegans STR-165 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001358 (Neuropeptide Y2 receptor)
31	H25P19.1	H25P19.1	n/a	chrV 688,859
32	B0564.7	B0564.7	n/a	chrIV 13,102,647	contains similarity to Aedes aegypti Cell cycle progression.; TR:Q16U20
33	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
34	C10C6.6	C10C6.6	n/a	chrIV 11,476,280	contains similarity to Pfam domains PF00122 (E1-E2 ATPase) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR008250 (E1-E2 ATPase-associated region), IPR006069 (ATPase, P-type cation exchange, alpha subunit), IPR006544 (P-type ATPase of unknown pump specificity (type V)), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
35	bag-1	F57B10.11	n/a	chrI 6,564,081	A homolog of the human BAG-family of co-chaperone proteins, negatively regulates Hsp70 and affects cell stress and cell growth.
36	T07D10.3	T07D10.3	n/a	chrI 12,627,858	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
37	F52B11.2	F52B11.2	n/a	chrIV 14,084,140	F52B11.2 is orthologous to the human gene PHOSPHOMANNOMUTASE 2 (PMS2; OMIM:601785), which when mutated leads to congenital disorder of glycosylation, type Ia.
38	srd-2	R05H5.1	n/a	chrII 10,186,817	C. elegans SRD-2 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
39	Y54E2A.12	Y54E2A.12	n/a	chrII 14,799,590	contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
40	Y48A5A.1	Y48A5A.1	n/a	chrIV 1,967,552	contains similarity to Pfam domain PF04925 SHQ1 protein contains similarity to Interpro domain IPR007009 (SHQ1 protein)
41	srh-244	C03G6.9	n/a	chrV 7,344,629	C. elegans SRH-244 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	fbxa-203	W05F2.5	n/a	chrI 3,372,801	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
43	T07D1.5	T07D1.5	n/a	chrX 2,419,146
44	duo-3	Y106G6H.12	n/a	chrI 10,467,681	C. elegans DUO-3 protein; contains similarity to Pfam domains PF00443 (Ubiquitin carboxyl-terminal hydrolase) , PF02338 (OTU-like cysteine protease) contains similarity to Interpro domains IPR003323 (Ovarian tumour, otubain), IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
45	F08F8.4	F08F8.4	n/a	chrIII 7,358,292	contains similarity to Interpro domain IPR001126 (UMUC-like DNA-repair protein)
46	srh-51	C10G11.3	n/a	chrI 6,301,375	C. elegans SRH-51 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	W01G7.4	W01G7.4	n/a	chrII 14,061,584	contains similarity to Danio rerio Protein SLC7A6OS (Solute carrier family 7 member 6 opposite strandstranscript homolog).; SW:Q5U3I2
48	grl-28	T24A6.15	n/a	chrV 3,551,603	grl-28 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
49	T21H3.5	T21H3.5	n/a	chrV 1,159,760
50	C32E8.5	C32E8.5	n/a	chrI 3,782,660	contains similarity to Pfam domain PF00498 FHA domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR000253 (Forkhead-associated)