UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C10H11.8	C10H11.8	0	chrI 4,736,771	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
4	C50B8.1	C50B8.1	n/a	chrV 13,566,397	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
5	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
6	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
7	hke-4.1	T28F3.3	n/a	chrIV 17,286,682	C. elegans HKE-4.1 protein; contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
8	F35G12.5	F35G12.5	n/a	chrIII 4,585,670	contains similarity to Wigglesworthia glossinidia brevipalpis RpoD protein.; TR:Q8D286
9	F44D12.7	F44D12.7	n/a	chrIV 10,035,774	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
10	prom-1	F26H9.1	n/a	chrI 9,288,599	prom-1 encodes an F-box protein orthologous to to human FBXO47 (OMIM:609498, deleted in renal cell carcinoma) and paralogous to F54D5.9, that is required during meiotic prophase I for homologous chromosome pairing and rapid meiotic progression; prom-1 mutants exhibit increased germline apoptosis, reduced and variable bivalent formation in meiotic prophase, reduced meiotic recombination, delayed meiotic entry, delayed and asynchronous nuclear reorganization in meiotic prophase, high embryonic lethality (averaging ~90%, but varying from 46-99% even in a null prom-1[ok1140] mutant strain), decreased brood sizes, and an abnormally high frequency of male progeny (22%, probably due to nonsegregating X chromsomes); the apoptotic phenotype of prom-1 is suppressed by spo-11(ok79), and prom-1 mutants show accumulated RAD-51 protein in meiotic nuclei, indicating that prom-1 meiotic defects arises from a failure to resolve meiotic double-stranded DNA breaks.
11	C16C8.14	C16C8.14	n/a	chrII 3,450,118	C16C8.14 encodes a Caenorhabditis-specific protein, with a central predicted coiled-coil and a C-terminal ubiqutin-like domain; C16C8.14 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51; C16C8.14 is paralogous to C16C8.4, C16C8.11, C16C8.12, C16C8.13, C16C8.15, C16C8.16, and F54D10.7.
12	msp-152	ZK546.6	n/a	chrII 4,933,207	msp-152 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
13	R148.4	R148.4	n/a	chrIII 3,172,188
14	cyp-35B3	K07C6.2	n/a	chrV 3,946,183	C. elegans CYP-35B3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
15	srp-5	C03G6.18	n/a	chrV 7,382,647	srp-5 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily; by homology, SRP-5 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases; however, as loss of srp-5 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-5 in C. elegans development and/or behavior is not yet known.
16	F07H5.10	F07H5.10	n/a	chrII 8,807,812	contains similarity to Arabidopsis thaliana Myosin heavy chain-like protein.; TR:Q9FJ35
17	C24F3.2	C24F3.2	n/a	chrIV 10,223,062	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016278 (Tyrosine protein phosphatase, dual specificity, 12), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
18	C45B2.1	C45B2.1	n/a	chrX 6,086,305
19	B0252.1	B0252.1	n/a	chrII 6,921,631	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR008266 (Tyrosine protein kinase, active site)
20	ZC410.3	ZC410.3	n/a	chrIV 9,077,529	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
21	F15D3.6	F15D3.6	n/a	chrI 11,574,794	contains similarity to Pfam domain PF04707 PRELI-like family contains similarity to Interpro domain IPR006797 (MSF1)
22	nnt-1	C15H9.1	n/a	chrX 6,124,888	nnt-1 encodes a proton-pumping nicotinamide nucleotide transhydrogenase predicted to be mitochondrial.
23	R02D3.8	R02D3.8	n/a	chrIV 256,589	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
24	T12B3.3	T12B3.3	n/a	chrIV 7,375,883	contains similarity to Pfam domain PF03009 Glycerophosphoryl diester phosphodiesterase family contains similarity to Interpro domain IPR004129 (Glycerophosphoryl diester phosphodiesterase)
25	cyp-37B1	F28G4.1	n/a	chrV 16,279,374	C. elegans CYP-37B1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
26	R12E2.2	R12E2.2	n/a	chrI 4,180,486	contains similarity to Pfam domain PF07738 Sad1 / UNC-like C-terminal contains similarity to Interpro domains IPR012919 (Sad1/UNC-like, C-terminal), IPR008979 (Galactose-binding like)
27	ego-1	F26A3.3	n/a	chrI 7,653,372	The ego-1 gene encodes a homolog of RNA-directed RNA polymerase that is essential for germ-line development.
28	C55B7.11	C55B7.11	n/a	chrI 6,512,726
29	zim-2	T07G12.10	n/a	chrIV 10,556,907	zim-2 encodes a protein with two C-terminal noncanonical C2H2 zinc-fingers whose paralogs include HIM-8, ZIM-1, ZIM-3, and C02F5.12; ZIM-2 is specifically required for homolog pairing, synapsis, and segregation of chromosome V during meiosis; zim-2(tm574) oocytes ending prophase have ~5 bivalents and ~2 univalents, the latter of which are consistently chromosome V; zim-2 oocytes fail to begin chromosome V pairing at the start of meiosis; ZIM-2 associates with the right end of chromosome V, which may indicate an association with its pairing center; while the C-terminal region of ZIM-2 most closely resembles those of its orthologs in other Caenorhabditis species, its N-terminal region instead most closely resembles those of its paralogs in C. elegans, indicating coevolving, species-specific functions; ZIM-2 foci, like HIM-8 foci, associate with the nuclear envelope during meiotic prophase; zim-2 mutants also have some defective segregation of the X chromosome (yielding a Him phenotype), but this may be an indirect effect of autosomal asynapsis.
30	F54D5.9	F54D5.9	n/a	chrII 11,543,652	F54D5.9 encodes an F-box protein orthologous to to human FBXO47 (OMIM:609498, deleted in renal cell carcinoma) and paralogous to PROM-1, that suppresses excess embryonic cell division; F54D5.9(RNAi) animals show hyperproliferating embryonic tissues, while having no obvious meiotic defects.
31	puf-12	ZK945.3	n/a	chrII 10,101,606	C. elegans PUF-12 protein; contains similarity to Pfam domain PF08144 CPL (NUC119) domain contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR012959 (CPL), IPR016024 (Armadillo-type fold)
32	Y49E10.4	Y49E10.4	n/a	chrIII 12,379,686	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR005788 (Disulphide isomerase), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related)
33	ZC317.7	ZC317.7	n/a	chrV 5,469,825	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003980 (Histamine H3 receptor)
34	F55G1.5	F55G1.5	n/a	chrIV 7,475,614	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
35	C50C3.1	C50C3.1	n/a	chrIII 8,192,662	contains similarity to Pfam domain PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) contains similarity to Interpro domain IPR000571 (Zinc finger, CCCH-type)
36	F49E8.2	F49E8.2	n/a	chrIV 7,549,959	contains similarity to Interpro domains IPR011767 (Glutaredoxin active site), IPR007087 (Zinc finger, C2H2-type)
37	B0238.9	B0238.9	n/a	chrV 5,276,818	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q16RM2
38	F55A11.7	F55A11.7	n/a	chrV 11,785,988	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
39	K02B2.3	K02B2.3	n/a	chrIV 5,938,425	contains similarity to Pfam domain PF04678 Protein of unknown function, DUF607 contains similarity to Interpro domain IPR006769 (Protein of unknown function DUF607)
40	F52H3.4	F52H3.4	n/a	chrII 10,041,733	contains similarity to Schizosaccharomyces pombe Protein gar2.; SW:P41891
41	K11H3.3	K11H3.3	n/a	chrIII 9,852,736	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
42	dct-12	Y57A10C.7	n/a	chrII 12,431,464	C. elegans DCT-12 protein ;
43	glh-2	C55B7.1	n/a	chrI 6,515,665	glh-2 encodes a putative DEAD-box RNA helicase that contains six CCHC zinc fingers and is homologous to Drosophila VASA, a germ-line-specific, ATP-dependent, RNA helicase; at non-permissive temperatures, GLH-2 plays a role in germ-line development and fertility, specifically in regulating the normal extent of germ-line proliferation, oogenesis, and the production of functional sperm; GLH-2 activity may also be required for the wild-type morphology of P granules and for localization of several protein components, but not accumulation of P granule mRNA components; GLH-2 interacts in vitro with itself and with KGB-1, a JNK-like MAP kinase; GLH-2 is a constitutive P granule component and thus, with the exception of mature sperm, is expressed in germ cells at all stages of development; GLH-2 is cytoplasmic in oocytes and the early embryo, while perinuclear in all later developmental stages as well as in the distal and medial regions of the hermaphrodite gonad; GLH-2 is expressed at barely detectable levels in males.
44	F56A3.1	F56A3.1	n/a	chrI 5,192,666
45	ZK418.8	ZK418.8	n/a	chrIII 7,084,302	contains similarity to Pfam domain PF00013 KH domain contains similarity to Interpro domains IPR009019 (K Homology, prokaryotic type), IPR004087 (K Homology), IPR004088 (K Homology, type 1)
46	lsl-1	F52F12.4	n/a	chrI 9,902,069	C. elegans LSL-1 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
47	srp-6	C03G6.19	n/a	chrV 7,385,156	srp-6 encodes a functional serpin (serine protease inhibitor)
48	F13E9.1	F13E9.1	n/a	chrIV 10,868,951	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (4), PF00787 (PX domain) contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR001683 (Phox-like), IPR003591 (Leucine-rich repeat, typical subtype)
49	mig-32	F11A10.3	n/a	chrIV 12,090,700	C. elegans MIG-32 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
50	bath-2	F52C6.11	n/a	chrII 1,922,182	C. elegans BATH-2 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)