UCSC C. elegans Gene Sorter

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

UCSC C. elegans Gene Sorter

genome assembly search

sort by display output

#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clc-1	C09F12.1	2e-107	chrX 11,048,302	clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes; clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva; in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	W09D12.1	W09D12.1	n/a	chrV 14,919,682	contains similarity to Pfam domain PF00413 Matrixin contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR006026 (Peptidase, metallopeptidases), IPR001818 (Peptidase M10A and M12B, matrixin and adamalysin), IPR002477 (Peptidoglycan binding-like), IPR016293 (Peptidase M10A, matrix metallopeotidase)
4	F47D12.3	F47D12.3	n/a	chrIII 6,298,853	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
5	C42D4.1	C42D4.1	n/a	chrIV 7,189,738	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domains IPR002395 (HMW kininogen), IPR003677 (Protein of unknown function DUF148)
6	hgo-1	W06D4.1	n/a	chrI 9,052,445	hgo-1 encodes a putative homogentisate 1,2-dioxygenase, orthologous to human HGD (OMIM:607474, mutated in alkaptonuria), that is required for normal resistance to hypertonic stress; HGO-1 is expressed in larval and adult hypodermis and intestine, and in larval pharynx; HGO-1 is required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
7	C50F7.3	C50F7.3	n/a	chrIV 7,733,257	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
8	F37C4.8	F37C4.8	n/a	chrIV 3,880,246
9	pah-1	K08F8.4	n/a	chrII 8,763,866	pah-1 encodes a biochemically active phenylalanine-4-hydroxylase orthologous to human PAH (OMIM:261600, mutated in phenylketonuria); recombinant PAH-1 has hydroxylase activity on phenylalanine and tryptophan substrates in vitro; pah-1 is expressed in seam cells, tail hypodermal cells, and ventral hypodermis, with stronger posterior than anterior expression; PAH-1 might help provide tyrosine for cross-linking in the cuticle, and is partially required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
10	C07E3.3	C07E3.3	n/a	chrII 10,355,550	contains similarity to Ambrosia artemisiifolia Pollen allergen Amb a 1.2 precursor (Antigen E) (Antigen Amb a I).; SW:MP12_AMBAR
11	H32K16.1	H32K16.1	n/a	chrI 9,151,388	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domain IPR013057 (Amino acid transporter, transmembrane)
12	srr-9	T05B11.2	n/a	chrV 7,738,784	C. elegans SRR-9 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
13	des-2	T26H10.1	n/a	chrV 11,417,794	des-2 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating the fast action of acetylcholine at neuromuscular junctions and in the nervous system; DES-2 is coexpressed with and genetically interacts with DEG-3, which which it probably forms heteromultimers, and DES-2 falls into the 'DEG-3' class of nAChR subunits, probably unique to nematodes, which includes DEG-3, ACR-5, ACR-17, ACR-18 ACR-20, and ACR-23.
14	sru-23	F36G9.6	n/a	chrV 15,971,479	C. elegans SRU-23 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR003839 (Protein of unknown function DUF215), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
15	T10B5.7	T10B5.7	n/a	chrV 1,847,108	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domain IPR002921 (Lipase, class 3)
16	C05C12.4	C05C12.4	n/a	chrIV 11,247,231	contains similarity to Interpro domains IPR002049 (EGF-like, laminin), IPR013032 (EGF-like region, conserved site)
17	srz-1	F14F8.3	n/a	chrV 16,676,674	srz-1 encodes a predicted seven-pass G protein-coupled receptor; as loss of srz-1 activity via large-scale RNAi screens results in no obvious abnormalities, the precise role of SRZ-1 in C. elegans development and/or behavior is not yet known.
18	K10G4.3	K10G4.3	n/a	chrV 17,264,477	contains similarity to Thermotoga maritima Probable DNA double-strand break repair rad50 ATPase.; SW:RA50_THEMA
19	W07A12.4	W07A12.4	n/a	chrII 9,150,253	contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF07707 (BTB And C-terminal Kelch) contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR011705 (BTB/Kelch-associated), IPR013089 (Kelch related)
20	T18D3.8	T18D3.8	n/a	chrX 12,437,812
21	tag-209	R06F6.11	n/a	chrII 10,787,542	C. elegans TAG-209 protein ;
22	F59A6.3	F59A6.3	n/a	chrII 5,009,745	contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
23	prx-2	ZK809.7	n/a	chrIV 11,645,165	prx-2 is orthologous to the human gene PEROXISOMAL MEMBRANE PROTEIN 3 (PXMP3; OMIM:170993), which when mutated leads to Zellweger syndrome 3 or infantile Refsum disease.
24	K02F3.9	K02F3.9	n/a	chrIII 840,905
25	skr-20	R12H7.5	n/a	chrX 13,223,155	The skr-20 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-20(RNAi) animals are at least superficially normal.
26	col-64	F52F12.2	n/a	chrI 9,894,637	C. elegans COL-64 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
27	F47D12.6	F47D12.6	n/a	chrIII 6,286,908
28	F22E5.7	F22E5.7	n/a	chrII 2,642,443
29	srw-72	F20E11.6	n/a	chrV 17,467,788	C. elegans SRW-72 protein ;
30	srz-20	F56D6.5	n/a	chrIV 3,916,211	C. elegans SRZ-20 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR001411 (Tetracycline resistance protein, TetB), IPR000576 (Proton/sugar symporter, LacY)
31	C34B2.3	C34B2.3	n/a	chrI 10,673,805	contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase)
32	K11G9.5	K11G9.5	n/a	chrV 6,687,134	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
33	Y37D8A.6	Y37D8A.6	n/a	chrIII 12,857,304	contains similarity to Interpro domains IPR006629 (LPS-induced tumor necrosis factor alpha factor), IPR013032 (EGF-like region, conserved site)
34	T12B3.3	T12B3.3	n/a	chrIV 7,375,883	contains similarity to Pfam domain PF03009 Glycerophosphoryl diester phosphodiesterase family contains similarity to Interpro domain IPR004129 (Glycerophosphoryl diester phosphodiesterase)
35	C24A11.6	C24A11.6	n/a	chrI 5,396,389
36	C14B1.3	C14B1.3	n/a	chrIII 3,704,316	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
37	inft-2	F15B9.4	n/a	chrV 13,004,645	C. elegans INFT-2 protein; contains similarity to Pfam domain PF02181 Formin Homology 2 Domain contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region), IPR003104 (Actin-binding FH2 and DRF autoregulatory), IPR000976 (Wilm's tumour protein)
38	Y69H2.11	Y69H2.11	n/a	chrV 18,644,329	contains similarity to Pfam domains PF00008 (EGF-like domain) (6), PF00858 (Amiloride-sensitive sodium channel) contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR001873 (Na+ channel, amiloride-sensitive)
39	ZC443.4	ZC443.4	n/a	chrV 12,818,211	contains similarity to Homo sapiens Isoform 4 of AT-rich interactive domain-containing protein 4B; ENSEMBL:ENSP00000375729
40	lec-4	C44F1.3	n/a	chrIII 3,772,356	lec-4 encodes a predicted galectin that exhibits sugar binding properties in vitro.
41	ttr-24	Y51A2D.9	n/a	chrV 18,555,981	C. elegans TTR-24 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
42	C17B7.2	C17B7.2	n/a	chrV 3,349,796	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
43	srr-3	F36D3.3	n/a	chrV 16,507,773	C. elegans SRR-3 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
44	Y66H1A.5	Y66H1A.5	n/a	chrIV 428,660
45	C33H5.13	C33H5.13	n/a	chrIV 7,791,950	contains similarity to Xenopus tropicalis UPF0467 protein C5orf32 homolog.; SW:Q28H62
46	snb-2	F23H12.1	n/a	chrV 12,345,050	C. elegans SNB-2 protein; contains similarity to Pfam domain PF00957 Synaptobrevin contains similarity to Interpro domains IPR016444 (Synaptobrevin, metazoa/fungi), IPR001388 (Synaptobrevin)
47	F22B3.8	F22B3.8	n/a	chrIV 11,423,572	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
48	bath-26	T07H3.6	n/a	chrII 1,600,097	C. elegans BATH-26 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
49	W03B1.9	W03B1.9	n/a	chrIV 4,354,761	contains similarity to Interpro domain IPR000694 (Proline-rich region)
50	C36C5.14	C36C5.14	n/a	chrV 3,165,115	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)