UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C08G5.6	C08G5.6	3e-98	chrII 771,341
2	Y116A8C.5	Y116A8C.5	n/a	chrIV 16,925,748	Y116A8C.5 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; Y116A8C.5 has no clear orthologs in other organisms.
3	B0228.9	B0228.9	n/a	chrII 7,762,795
4	F42G2.6	F42G2.6	n/a	chrII 2,428,176	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000533 (Tropomyosin), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
5	T09F5.2	T09F5.2	n/a	chrV 15,151,275	contains similarity to Saccharomyces cerevisiae cell wall mannoprotein; SGD:YOR009W
6	Y54G9A.1	Y54G9A.1	n/a	chrII 13,700,041	contains similarity to Carabus linnei NADH dehydrogenase subunit 5 (Fragment).; TR:O79584
7	C08E3.13	C08E3.13	n/a	chrII 1,632,158	C08E3.13 encodes a novel protein; expression studies indicate that C08E3.13 expression is positively regulated by signaling through the DBL-1/TGF-beta signaling pathway; in situ hybridization experiments reveal that C08E3.13 transcripts are expressed in the intestine and the vulva.
8	C03B1.1	C03B1.1	n/a	chrX 6,374,577
9	F23B2.10	F23B2.10	n/a	chrIV 9,153,550	contains similarity to Interpro domain IPR001841 (Zinc finger, RING-type)
10	T15D6.9	T15D6.9	n/a	chrI 12,392,786	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
11	srg-39	T19C4.2	n/a	chrV 11,151,861	C. elegans SRG-39 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
12	C35C5.2	C35C5.2	n/a	chrX 11,539,654	contains similarity to Pfam domains PF04389 (Peptidase family M28) , PF02225 (PA domain) , PF04253 (Transferrin receptor-like dimerisation domain) contains similarity to Interpro domains IPR007365 (Transferrin receptor-like, dimerisation), IPR007484 (Peptidase M28), IPR003137 (Protease-associated PA)
13	str-204	F10D2.1	n/a	chrV 7,160,334	C. elegans STR-204 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	F41E7.6	F41E7.6	n/a	chrX 10,308,733	contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domain IPR000542 (Acyltransferase ChoActase/COT/CPT)
15	srab-25	ZK697.7	n/a	chrV 1,740,043	C. elegans SRAB-25 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
16	T07A5.1	T07A5.1	n/a	chrIII 10,304,668	contains similarity to Pfam domain PF06828 Fukutin-related contains similarity to Interpro domain IPR009644 (Fukutin-related)
17	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
18	B0496.1	B0496.1	n/a	chrIV 7,446,888	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
19	srw-10	ZC482.6	n/a	chrIII 12,755,860	C. elegans SRW-10 protein ;
20	srx-19	T05A12.1	n/a	chrIV 6,874,033	C. elegans SRX-19 protein ;
21	xnp-1	B0041.7	n/a	chrI 4,668,742	xnp-1 encodes an ATP-dependent DNA helicase of the SNF2 family that is orthologous to human XNP/ATR-X, which is associated with a number of X-linked mental retardation syndromes; in C. elegans, xnp-1 activity is required at high temperatures for embryogenesis, somatic gonad development, fertility, and vulval morphogenesis; in addition, animals doubly mutant for xnp-1 and lin-35/Rb, hpl-2/HP1, or nucleosome remodelling and histone deacetylase (NuRD) complex members such as lin-53 and let-418, display larval arrest with growth cessation but continued cell proliferation; xnp-1 is also required, with lin-35/Rb and hpl-2/HP1, for proper regulation of transgene expression; xnp-1 mRNA, detectable in embryos and the germline by in situ hybridization, is expressed at highest levels in embryos with decreasing levels seen in successive larval stages; xnp-1 transcriptional reporter fusions exhibit strong expression beginning at mid-embryogenesis but fading by embryonic morphogenesis; at hatching, expression is observed in all dividing cells including the P lineage, and at later larval stages expression is observed in the vulval precursor cells.
22	srh-109	T19C9.4	n/a	chrV 17,219,817	C. elegans SRH-109 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	Y45G12C.11	Y45G12C.11	n/a	chrV 2,551,494	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
24	uvt-3	C42D8.3	n/a	chrX 5,090,152	C. elegans UVT-3 protein; contains similarity to Pfam domain PF03630 Fumble contains similarity to Interpro domains IPR002791 (Protein of unknown function DUF89), IPR015844 (Pantothenate kinase, acetyl-CoA regulated, two-domain type), IPR011602 (Fumble)
25	F44A2.2	F44A2.2	n/a	chrV 9,319,570	contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF07885 (Ion channel) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003971 (Potassium channel, voltage dependent, Kv9), IPR003968 (Potassium channel, voltage dependent, Kv), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR003091 (Voltage-dependent potassium channel), IPR013099 (Ion transport 2), IPR003974 (Potassium channel, voltage dependent, Kv3)
26	sri-45	K07E8.9	n/a	chrII 660,949	C. elegans SRI-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	Y59C2A.1	Y59C2A.1	n/a	chrII 2,210,488	contains similarity to Pfam domain PF00246 Zinc carboxypeptidase contains similarity to Interpro domains IPR000834 (Peptidase M14, carboxypeptidase A), IPR009020 (Proteinase inhibitor, propeptide), IPR000276 (GPCR, rhodopsin-like)
28	Y38H6C.17	Y38H6C.17	n/a	chrV 20,537,681	Y38H6C.17 encodes a putative amino acid transporter that inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51; Y38H6C.17 has 11 predicted transmembrane alpha-helices; Y38H6C.17 has multiple C. elegans paralogs and non-nematode orthologs, including budding yeast AVT3 and AVT4 and human SLC36A1 (OMIM:606561).
29	C08F1.8	C08F1.8	n/a	chrII 1,806,228
30	F11A5.7	F11A5.7	n/a	chrV 16,205,976	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
31	ZK1037.1	ZK1037.1	n/a	chrV 15,311,784	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
32	pha-2	M6.3	n/a	chrX 635,373	pha-2 encodes a homeodomain protein that is orthologous to vertebrate Hex proteins required for the development of B lymphocytes and organs derived from foregut endoderm; in C. elegans, pha-2 is essential for proper development and morphogenesis of the pm5 pharyngeal muscles cells during late stages of embryogenesis; in regulating pm5 fate specification, PHA-2 appears to act downstream of the organ identity factor PHA-4, and upstream of ceh-22, whose expression it may negatively regulate in pm5; a rescuing PHA-2::GFP reporter is expressed in pharyngeal cells, intestinal-rectal cells, and postembryonic head neurons.
33	C17B7.8	C17B7.8	n/a	chrV 3,322,428	C17B7.8 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C17B7.8 has no clear orthologs in other organisms.
34	R08F11.7	R08F11.7	n/a	chrV 3,791,935	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal)
35	srh-296	Y94A7B.4	n/a	chrV 17,811,540	C. elegans SRH-296 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	T05A6.5	T05A6.5	n/a	chrII 7,824,034	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
37	ncr-2	F09G8.4	n/a	chrIII 8,261,990	ncr-2 encodes a homolog of human NPC1, which when mutated leads to Niemann-Pick disease, type C (OMIM:257220).
38	K03E5.1	K03E5.1	n/a	chrI 3,431,349	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domains IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR000859 (CUB)
39	C36C5.15	C36C5.15	n/a	chrV 3,168,358	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
40	srbc-24	C45H4.10	n/a	chrV 2,152,386	C. elegans SRBC-24 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
41	T24H10.4	T24H10.4	n/a	chrII 9,110,325	contains similarity to Pfam domain PF05705 Eukaryotic protein of unknown function (DUF829) contains similarity to Interpro domain IPR008547 (Protein of unknown function DUF829, eukaryotic)
42	M162.6	M162.6	n/a	chrV 19,782,521	contains similarity to Interpro domain IPR016187 (C-type lectin fold)
43	C04B4.6	C04B4.6	n/a	chrX 12,275,348	contains similarity to Corynebacterium efficiens Putative alanyl-tRNA synthetase.; TR:Q8FT23
44	C03D6.1	C03D6.1	n/a	chrI 9,669,662	contains similarity to Canine parvovirus Coat protein VP1 [Contains: Coat protein VP2].; SW:COAT_PAVC7
45	ceh-30	C33D12.7	n/a	chrX 3,064,554	ceh-30 encodes a homeodomain protein most similar to Drosophila and mammalian BarH1 (OMIM:605211) which function in neuronal cell fate determination; the precise biological role of CEH-30 in C. elegans development and/or behavior is not yet known.
46	F19B10.5	F19B10.5	n/a	chrII 3,656,709
47	sre-5	B0212.2	n/a	chrIV 3,566,503	C. elegans SRE-5 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
48	C03A7.13	C03A7.13	n/a	chrV 5,191,814	contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
49	elks-1	F42A6.9	n/a	chrIV 3,346,268	elks-1 encodes the C. elegans homolog of the vertebrate ELKS (glutamine, leucine, lysine, and serine-rich) proteins; although loss of elks-1 activity results in no obvious developmental or behavioral abnormalities, the ELKS-1 C-terminus interacts with the PDZ domain of UNC-10/RIM in vitro, and in vivo each protein appears to play a nonessential role in localizing the other to the presynaptic active zone; in addition to the active zone, ELKS-1 also localizes to the pharyngeal basal lamina.
50	srw-113	ZK1037.9	n/a	chrV 15,333,837	C. elegans SRW-113 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)