UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxa-160	C08E3.12	5e-141	chrII 1,624,293	C. elegans FBXA-160 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
2	F15E6.5	F15E6.5	n/a	chrIV 4,289,807	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
3	ZK669.2	ZK669.2	n/a	chrII 7,937,580	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
4	ZK512.2	ZK512.2	n/a	chrIII 9,143,217	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
5	F11A1.2	F11A1.2	n/a	chrX 10,658,016
6	osm-12	Y75B8A.12	n/a	chrIII 12,196,633	C. elegans OSM-12 protein; contains similarity to Interpro domain IPR016575 (Bardet-Biedl syndrome 7 protein)
7	F34D6.2	F34D6.2	n/a	chrII 2,683,818	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000047 (Helix-turn-helix motif, lambda-like repressor), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
8	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
9	mel-26	ZK858.4	n/a	chrI 9,134,137	mel-26 encodes a MATH and BTB/POZ domain-containing protein that functions as a novel substrate-specific adaptor of the CUL-3-containing E3 ubiquitin ligase; MEL-26 is required maternally for formation of mitotic spindles in the early embryo, and as a component of a ubiquitin ligase complex, for degradation of the microtubule-severing protein MEI-1 at the meiosis to mitosis transition; MEL-26 is also required maternally for embryonic morphogenesis; since MEL-26 contains a meprin-associated Traf homology (MATH) domain, it might be involved in apoptosis.
10	Y51H1A.7	Y51H1A.7	n/a	chrII 13,897,024	contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000783 (RNA polymerase, subunit H/Rpb5 C-terminal)
11	C17B7.7	C17B7.7	n/a	chrV 3,326,895	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
12	R05A10.5	R05A10.5	n/a	chrIV 14,169,839	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
13	srt-7	C50H11.4	n/a	chrV 3,082,398	C. elegans SRT-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000408 (Regulator of chromosome condensation, RCC1)
14	F13B9.6	F13B9.6	n/a	chrX 8,266,671	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
15	C01G5.7	C01G5.7	n/a	chrIV 6,518,588
16	srz-74	K03D3.1	n/a	chrIV 16,330,219	C. elegans SRZ-74 protein ;
17	puf-4	M4.2	n/a	chrIV 3,207,566	C. elegans PUF-4 protein; contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
18	F08C6.5	F08C6.5	n/a	chrX 7,560,915	contains similarity to Interpro domain IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site)
19	R119.5	R119.5	n/a	chrI 391,462	contains similarity to Pfam domain PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) contains similarity to Interpro domain IPR000682 (Protein-L-isoaspartate(D-aspartate) O-methyltransferase)
20	F43B10.1	F43B10.1	n/a	chrX 16,662,035
21	clec-121	Y25C1A.4	n/a	chrII 3,103,522	C. elegans CLEC-121 protein; contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
22	F11D11.4	F11D11.4	n/a	chrV 18,762,417	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
23	gcy-27	C06A12.4	n/a	chrIV 17,436,419	C. elegans GCY-27 protein; contains similarity to Pfam domains PF00211 (Adenylate and Guanylate cyclase catalytic domain) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001054 (Adenylyl cyclase class-3/4/guanylyl cyclase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
24	W03G9.7	W03G9.7	n/a	chrI 4,988,180	contains similarity to Methanocaldococcus jannaschii Chromosome partition protein smc homolog.; SW:Q59037
25	srx-44	T10C6.4	n/a	chrV 16,021,667	C. elegans SRX-44 protein ; contains similarity to Rattus norvegicus Blue-sensitive opsin (BOP) (Blue cone photoreceptor pigment) (Shortswavelength-sensitive cone opsin) (S opsin).; SW:Q63652
26	srj-9	T20C4.1	n/a	chrV 3,432,956	C. elegans SRJ-9 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	ncx-6	C07A9.4	n/a	chrIII 9,712,021	ncx-6 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-7/-10; NCX-6 may function intracellularly; NCX-6 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-6 has no obvious function in mass RNAi assays.
28	H03G16.1	H03G16.1	n/a	chrX 15,054,187	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
29	EEED8.4	EEED8.4	n/a	chrII 5,410,795	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
30	B0432.1	B0432.1	n/a	chrII 298,462
31	F26D2.14	F26D2.14	n/a	chrV 16,436,268	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
32	clec-34	T25E12.8	n/a	chrV 16,736,555	C. elegans CLEC-34 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	Y48E1B.7	Y48E1B.7	n/a	chrII 13,580,236	Y48E1B.7 encodes a C2H2-type zinc-finger protein required for embryonic development and fertility; Y48E1B.7 transcript levels are diminished by ERI-1, RDE-3, and RRF-2, perhaps through endogenous RNAi; Y48E1B.7 is paralogous to MCD-1, but has no obvious non-nematode orthologs; Y48E1B.7 contains a single central zinc-finger and a C-terminal low-complexity region, but no other recognizable protein domains.
34	srw-26	T05G11.3	n/a	chrV 15,931,865	C. elegans SRW-26 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
35	K10B4.4	K10B4.4	n/a	chrII 124,170	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002286 (P2 purinoceptor), IPR005390 (Neuromedin U receptor), IPR000276 (GPCR, rhodopsin-like)
36	knl-1	C02F5.1	n/a	chrIII 8,252,399	knl-1 encodes a novel acidic protein with a coiled-coil region at its C-terminus; KNL-1 is an essential kinetochore component that is required for proper spindle elongation and chromosome separation, and in the kinetochore assembly pathway, plays a key role in linking the initiation of kinetochore formation with the construction of a functional microtubule-binding interface; in the assembly pathway, KNL-1 functions downstream of the DNA-proximal kinetochore components CeCENP-A/HCP-3 and CeCENP-B/HCP-4 and upstream of the outer kinetochore components HIM-10/Nuf2p, NDC-80/HEC1, CeBUB-1, HCP-1, and CeCLASP2/CLS-2; in expression studies in the one-cell embryo, KNL-1 localizes to kinetochores throughout mitosis.
37	srbc-17	C45H4.3	n/a	chrV 2,178,415	C. elegans SRBC-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
38	EEED8.6	EEED8.6	n/a	chrII 5,385,733	EEED8.6 encodes an ATP/ADP-activated metallocarboxypeptidase, orthologous to mammalian AGBL4 proteins, that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; recombinant EEED8.6 is active in vitro on several different C-terminal amino acids of synthetic peptide substrates (with carboxypeptidase A- and B-like, but not O-like specificity); unlike most carboxypeptidases, but like tubulin carboxypeptidase, EEED8.6 is inhibited by high salt or by Z-Glu-Tyr dipeptide; EEED8.6 and its mammalian AGBL4 orthologs, along with other proteins such as mammalian AGBL5, comprise a M14D2 peptidase subfamily; by homolog-based structural modelling, EEED8.6 is predicted to have an unusually open active site.
39	K09E2.2	K09E2.2	n/a	chrX 8,677,297
40	T19C3.6	T19C3.6	n/a	chrIII 629,578
41	W05H5.1	W05H5.1	n/a	chrII 12,443,814	contains similarity to Ovis aries Lysophosphatidic acid receptor Edg-2 (LPA receptor 1) (LPA-1).; SW:EDG2_SHEEP
42	C53B7.6	C53B7.6	n/a	chrX 6,868,654
43	ZK1055.5	ZK1055.5	n/a	chrV 6,582,618	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
44	str-198	ZK285.1	n/a	chrV 16,048,450	C. elegans STR-198 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	K04H8.2	K04H8.2	n/a	chrI 14,254,220	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
46	F19G12.3	F19G12.3	n/a	chrX 1,425,941	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
47	cdc-25.2	F16B4.8	n/a	chrV 1,581,313	cdc-25.2 encodes a putative homolog of Cdc25 phosphatase protein family that affects germline proliferation.
48	T10E9.8	T10E9.8	n/a	chrI 6,540,502
49	ace-2	Y44E3A.2	n/a	chrI 3,304,491	An acetylcholineesterase involved in the termination of cholinergic nerve transmission; it is predominantly expressed in motoneurons.
50	glb-10	C29F5.7	n/a	chrII 6,308,800	glb-10 encodes a globin; glb-10 is expressed in pharynx, intestine, vulval muscle, and many neurons, with at least some subcellular localization to synapses; however, glb-10 has no obvious function in mass RNAi assays.