UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clec-162	C07A9.1	4e-171	chrIII 9,724,149	C. elegans CLEC-162 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
2	acy-3	C44F1.5	n/a	chrIII 3,778,374	acy-3 encodes a predicted member of the adenylyl cyclase family with highest similarity to human adenylate cyclase type 5; expressed in the support cells of ciliated neurons, in the head and tail ganglia, in two pairs of neurons in the retrovesicular ganglia, and in the spermatheca.
3	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	wht-6	T26A5.1	n/a	chrIII 6,473,428	C. elegans WHT-6 protein; contains similarity to Pfam domains PF01061 (ABC-2 type transporter) , PF00005 (ABC transporter) contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR003593 (AAA+ ATPase, core), IPR013525 (ABC-2 type transporter)
5	T20D3.11	T20D3.11	n/a	chrIV 9,349,648	contains similarity to Anopheles gambiae str PEST AGAP009276-PA (Fragment).; TR:Q7PVH5
6	spe-4	ZK524.1	n/a	chrI 7,455,774	spe-4 encodes a transmembrane protein that is a divergent member of the presenilin family of proteins that have been implicated in early-onset Alzheimer's disease (OMIM:104300); spe-4 activity is required for proper formation and function of the fibrous body-membranous organelles that are asymmetrically localized to spermatids during spermatogeneis; spe-4 is also required for proper partitioning of tubulin as spermatids bud from the residual body; spe-4 localizes to the fibrous body-membranous organelles of developing spermatocytes and also to the spermatozoon cell body.
7	far-5	F15B9.3	n/a	chrV 12,996,198	far-5 encodes a member of a class of fatty acid-and retinol-binding proteins that are known to be secreted by parasitic nematodes and plants; far-5 binds lipid in fluorescence-based assays, however, the precise function of far-5 is not known.
8	W03G9.5	W03G9.5	n/a	chrI 4,969,127	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
9	K11H12.4	K11H12.4	n/a	chrIV 674,988	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
10	F11A5.4	F11A5.4	n/a	chrV 16,195,957	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR001019 (Guanine nucleotide binding protein (G-protein), alpha subunit), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)
11	D1065.3	D1065.3	n/a	chrV 4,060,947	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
12	F13H8.9	F13H8.9	n/a	chrII 6,280,371	contains similarity to Pfam domain PF00266 Aminotransferase class-V contains similarity to Interpro domains IPR016454 (Cysteine desulphurase, NifS), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
13	srh-44	B0334.7	n/a	chrII 11,516,530	C. elegans SRH-44 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	ins-24	ZC334.3	n/a	chrI 14,031,394	ins-24 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-24 is one of 38 insulin-like peptides in C. elegans, but as loss of INS-24 function via RNA-mediated interference does not result in any abnormalities, the precise role of INS-24 in C. elegans development is not yet clear.
15	sfxn-1.1	AH6.2	n/a	chrII 9,518,171	C. elegans SFXN-1.1 protein; contains similarity to Pfam domain PF03820 Tricarboxylate carrier contains similarity to Interpro domain IPR004686 (Tricarboxylate/iron carrier)
16	acy-1	F17C8.1	n/a	chrIII 4,726,505	The acy-1 gene encodes a protein with 40% identity to mammalian adenylyl cyclases, most closely related to the divergent mouse isoform type IX, that affects viability, muscle contraction, locomotion, and molting; it acts genetically downstream of gsa-1 and is expressed in excitable cells.
17	pqn-2	AC3.4	n/a	chrV 10,383,199	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
18	osm-6	R31.3	n/a	chrV 11,925,995	osm-6 encodes a novel protein that is orthologous to the IFT52 component of the intraflagellar transport particle; osm-6 activity is required cell autonomously for proper sensory cilium structure and thus for normal ciliated sensory neuron function; OSM-6 is a component of the intraflagellar transport particle subcomplex B, and OSM-6::GFP reporter fusions are expressed exclusively in ciliated sensory neurons.
19	H35B03.1	H35B03.1	n/a	chrIV 5,727,641
20	C33E10.5	C33E10.5	n/a	chrX 17,276,148	contains similarity to Interpro domain IPR000173 (Glyceraldehyde 3-phosphate dehydrogenase)
21	F28G4.5	F28G4.5	n/a	chrV 16,290,444	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
22	mrp-6	F20B6.3	n/a	chrX 4,182,153	C. elegans MRP-6 protein; contains similarity to Pfam domains PF00664 (ABC transporter transmembrane region) (2), PF00005 (ABC transporter) (2)contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR011527 (ABC transporter, transmembrane region, type 1), IPR001140 (ABC transporter, transmembrane region), IPR009147 (Cystic fibrosis transmembrane conductance regulator), IPR003593 (AAA+ ATPase, core)
23	ist-1	C54D1.3	n/a	chrX 7,135,879	ist-1 encodes a pleckstrin homology (PH) and phosphotyrosine binding (PTB) domain-containing insulin receptor substrate (IRS) homolog that negatively regulates lifespan and dauer development; IST-1 potentiates insulin-like signaling, although it is not absolutely required for such signaling under most conditions; in addition to acting through the AGE-1/PI3K branch of the insulin-like signaling pathway, IST-1 may also function in a parallel pathway to activate downstream protein-kinase Bs encoded by akt-1 and akt-2.
24	F21F3.3	F21F3.3	n/a	chrI 4,902,556	contains similarity to Pfam domain PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family contains similarity to Interpro domains IPR007269 (Isoprenylcysteine carboxyl methyltransferase), IPR001958 (Tetracycline resistance protein, TetA)
25	eat-2	Y48B6A.4	n/a	chrII 14,169,168	eat-2 encodes a ligand-gated ion channel subunit most closely related to the non-alpha-subunits of nicotinic acetylcholine receptors (nAChR); EAT-2 functions postsynaptically in pharyngeal muscle to regulate the rate of pharyngeal pumping; eat-2 is also required for normal life span and defecation; a functional EAT-2::GFP fusion protein localizes to two small dots near the junction of pharyngeal muscles pm4 and pm5, which is the site of the posterior-most MC motor neuron processes and the MC synapse; eat-2 genetically interacts with eat-18, which encodes a predicted novel transmembrane protein expressed in pharyngeal muscle and required for proper function of pharyngeal nicotonic receptors.
26	srd-70	F48F5.4	n/a	chrV 20,450,660	C. elegans SRD-70 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	C34F6.9	C34F6.9	n/a	chrX 11,220,316	contains similarity to Interpro domain IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
28	F22G12.5	F22G12.5	n/a	chrI 13,172,567	contains similarity to Interpro domain IPR001765 (Carbonic anhydrase)
29	F57A8.7	F57A8.7	n/a	chrV 10,076,747	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
30	pptr-1	W08G11.4	n/a	chrV 16,362,503	C. elegans PPTR-1 protein; contains similarity to Pfam domain PF01603 Protein phosphatase 2A regulatory B subunit (B56 family) contains similarity to Interpro domains IPR002554 (Protein phosphatase 2A, regulatory B subunit, B56), IPR016024 (Armadillo-type fold)
31	T02H6.5	T02H6.5	n/a	chrII 687,130	contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
32	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
33	acs-17	C46F4.2	n/a	chrX 5,939,959	C. elegans ACS-17 protein; contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
34	F11A10.4	F11A10.4	n/a	chrIV 12,101,240	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR013324 (RNA polymerase sigma factor, regions 3 and 4), IPR016024 (Armadillo-type fold)
35	F42G2.5	F42G2.5	n/a	chrII 2,417,192	contains similarity to Pfam domains PF00635 (MSP (Major sperm protein) domain) , PF00097 (Zinc finger, C3HC4 type (RING finger)) contains similarity to Interpro domains IPR008962 (PapD-like), IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000535 (Major sperm protein)
36	C06C6.6	C06C6.6	n/a	chrV 15,990,153	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
37	F16B12.7	F16B12.7	n/a	chrX 14,109,051	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
38	R01H2.4	R01H2.4	n/a	chrIII 7,062,521	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
39	Y56A3A.2	Y56A3A.2	n/a	chrIII 11,856,255	contains similarity to Pfam domain PF02163 Peptidase family M50 contains similarity to Interpro domains IPR008915 (Peptidase M50), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001193 (Peptidase M50, mammalian sterol-regulatory element binding protein)
40	gcy-18	ZK896.8	n/a	chrIV 12,863,005	gcy-18 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-18 functions redundantly with gcy-8 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, microarray experiments indicate that gcy-18 expression is induced in daf-16(RNAi); daf-2(RNAi) double mutants and repressed in daf-2(RNAi) mutants, suggesting that GCY-18 activity may contribute to a shortened lifespan; consistent with this, loss of gcy-18 activity via RNAi does result in lifespan extension; GCY-18 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
41	srxa-15	Y44A6B.2	n/a	chrV 20,638,710	C. elegans SRXA-15 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
42	sulp-8	ZK287.2	n/a	chrV 9,671,599	sulp-8 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-8 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a SULP-8::GFP fusion is expressed in the basolateral membrane of the excretory cell, intestine, and rectal gland cells.
43	srab-4	C33G8.5	n/a	chrV 7,004,969	C. elegans SRAB-4 protein ;
44	F22E5.13	F22E5.13	n/a	chrII 2,648,208
45	sur-6	F26E4.1	n/a	chrI 9,756,000	C. elegans SUR-6 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR000009 (Protein phosphatase 2A, regulatory subunit PR55), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
46	T10B9.9	T10B9.9	n/a	chrII 9,775,421	contains similarity to Avian adenovirus gal1 Orf2 protein.; TR:Q64786
47	T11F1.3	T11F1.3	n/a	chrII 2,955,703
48	frm-7	C51F7.1	n/a	chrV 12,304,705	C. elegans FRM-7 protein; contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR000299 (Band 4.1, N-terminal)
49	Y81G3A.4	Y81G3A.4	n/a	chrII 13,092,774	contains similarity to Guillardia theta 60S acidic ribosomal protein P0.; TR:Q98S65
50	fis-1	F41G3.4	n/a	chrII 6,755,453	C. elegans FIS-1 protein; contains similarity to Interpro domains IPR016543 (Tetratricopeptide repeat 11 Fission 1 protein), IPR011990 (Tetratricopeptide-like helical)