UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C06E1.1	C06E1.1	9e-92	chrIII 8,606,076	contains similarity to Pfam domain PF03134 TB2/DP1, HVA22 family contains similarity to Interpro domain IPR004345 (TB2/DP1 and HVA22 related protein)
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	F38A5.7	F38A5.7	n/a	chrIV 6,602,016
4	sdz-19	F45E6.6	n/a	chrX 12,502,884	C. elegans SDZ-19 protein ;
5	sdz-16	F31E9.4	n/a	chrV 17,327,178	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
6	sdz-3	C29F5.2	n/a	chrII 6,300,414	C. elegans SDZ-3 protein ;
7	fbxb-52	K05F6.6	n/a	chrII 1,548,512	C. elegans FBXB-52 protein; contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF07735 (F-box associated) contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR012885 (F-box associated type 2), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
8	W04H10.2	W04H10.2	n/a	chrII 606,109
9	W10D9.1	W10D9.1	n/a	chrII 454,887
10	F35F10.12	F35F10.12	n/a	chrV 3,314,352	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000694 (Proline-rich region), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
11	M28.4	M28.4	n/a	chrII 10,645,246	contains similarity to Homo sapiens Kinesin-like protein 2; ENSEMBL:ENSP00000324020
12	nhr-127	T13F3.3	n/a	chrV 16,263,066	nhr-127 encodes a member of the nuclear hormone receptor family; expressed in hypodermal seam cells from the embryonic 1.5-fold stage until the L1 larval stage.
13	fut-6	T05A7.5	n/a	chrII 4,654,556	C. elegans FUT-6 protein; contains similarity to Pfam domain PF00852 Glycosyltransferase family 10 (fucosyltransferase) contains similarity to Interpro domain IPR001503 (Glycosyl transferase, family 10)
14	clec-141	EEED8.11	n/a	chrII 5,406,695	C. elegans CLEC-141 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
15	F53B3.5	F53B3.5	n/a	chrX 2,876,207	F53B3.5 encodes a claudin homolog that may regulate ion channels; F53B3.5 is distantly similar to mammalian voltage-dependent calcium channel gamma subunits that are known or suspected to prevent epilepsy in vivo (e.g., stargazin; MGI:1316660); F53B3.5 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
16	fbxb-24	Y56A3A.15	n/a	chrIII 11,909,309	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
17	K05C4.9	K05C4.9	n/a	chrI 14,728,785	contains similarity to Pfam domain PF00560 Leucine Rich Repeat
18	fbxb-71	F40F4.1	n/a	chrX 3,263,537	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
19	str-13	C24B9.8	n/a	chrV 2,726,550	C. elegans STR-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	C07A9.9	C07A9.9	n/a	chrIII 9,665,312	contains similarity to Guillardia theta RNA polymerase sigma factor.; TR:Q8S9D0
21	srj-20	Y45G12C.15	n/a	chrV 2,572,367	C. elegans SRJ-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	ceh-43	C28A5.4	n/a	chrIII 4,448,260	A homeobox protein of the Distal-less (Dll) class that is required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability; it is predominantly expressed in the head hypdodermis, neuronal support cells and CAN neurons.
23	C54E10.6	C54E10.6	n/a	chrV 18,808,334	contains similarity to Saccharomyces cerevisiae Spindle Pole Component of molecular weight 24kDa; SGD:YMR117C
24	F28H1.1	F28H1.1	n/a	chrI 3,996,331
25	R02F2.2	R02F2.2	n/a	chrIII 5,493,250	contains similarity to Pfam domain PF00621 RhoGEF domain contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR011046 (WD40 repeat-like), IPR001331 (Guanine-nucleotide dissociation stimulator, CDC24, conserved site)
26	F08G12.5	F08G12.5	n/a	chrX 11,309,490	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
27	F42A10.6	F42A10.6	n/a	chrIII 6,176,450
28	sdz-18	F45C12.11	n/a	chrII 1,705,740	C. elegans SDZ-18 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
29	F57A8.1	F57A8.1	n/a	chrV 10,045,776	contains similarity to Interpro domain IPR009058 ()
30	F59H6.5	F59H6.5	n/a	chrII 2,005,814	contains similarity to Pfam domain PF05970 Eukaryotic protein of unknown function (DUF889) contains similarity to Interpro domains IPR010285 (Protein of unknown function DUF889, eukaryote), IPR003593 (AAA+ ATPase, core), IPR006034 (Asparaginase/glutaminase)
31	T11A5.1	T11A5.1	n/a	chrV 9,859,109	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR008162 (Inorganic pyrophosphatase)
32	EEED8.2	EEED8.2	n/a	chrII 5,417,509	contains similarity to Interpro domains IPR012674 (Calycin), IPR011038 (Calycin-like), IPR000463 (Cytosolic fatty-acid binding)
33	unc-75	C17D12.2	n/a	chrI 11,596,943	unc-75 encodes an RNA-binding protein with two N-terminal RNA recognition motifs (RRMs), a glutamine/asparagine-rich linker domain, and a third C-terminal RRM; UNC-75 is orthologous to mammalian CELF/BrunoL proteins that control pre-mRNA splicing; unc-75 is expressed in all neurons and in neurosecretory gland cells, and is required for normal modulation of GABA- and acetylcholine-mediated neurotransmission; UNC-75 protein is found with other RRM proteins in dynamic nuclear speckles, consistent with a role in alternative mRNA splicing; unc-75 mutations can be rescued in vivo by a human unc-75 transgene, but not by exc-7 or W02D3.11, indicating that UNC-75 acts on evolutionarily conserved but highly specific pre-mRNA substrates; both UNC-75 and EXC-7 are required in parallel for normal cholinergic neurotransmission.
34	ifta-2	T28F3.6	n/a	chrIV 17,301,376	ifta-2 encodes a ciliary protein, orthologous to human RABL5, that is required for normally short life span and dauer formation; IFTA-2 is expressed in amphid, labial, and phasmid ciliated sensory neurons; intracellularly, IFTA-2 resides in the bases and axonemes of cilia, colocalizing with DAF-2 and AGE-1; IFTA-2 may be either a cargo or a cargo-docking component of intraflagellar transport (IFT) by the IFT-B complex; ciliary basal localization of IFTA-2 is abolished by a T42N mutation predicted to lock ITFA-2 into an inactive, GDP-bound conformation; ifta-2(tm1724) mutants have abnormally long lifespans and constitutive dauer formation, perhaps because IFTA-2 regulates DAF-2 signalling from ciliated sensory neurons; IFTA-2 is not required for cilium assembly or IFT, nor is it required for chemosensation or osmosensation; the ciliary localization of IFTA-2 is conserved in RABL5; via an X-box in its promoter, ifta-2 is a candidate for direct regulation by DAF-19.
35	srh-79	C04F2.1	n/a	chrV 7,498,378	C. elegans SRH-79 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
36	Y43F8B.10	Y43F8B.10	n/a	chrV 19,475,668
37	rab-14	K09A9.2	n/a	chrX 15,605,871	rab-14 encodes a member of the Rab GTPase family.
38	C05E11.3	C05E11.3	n/a	chrX 4,580,554	contains similarity to Mus musculus Lysosomal-associated transmembrane protein 4A (Golgi 4-transmembranesspanning transporter) (Mouse transporter protein) (MTP).; SW:Q60961
39	R04B3.1	R04B3.1	n/a	chrX 2,468,815	contains similarity to Interpro domain IPR000998 (MAM)
40	F33E2.6	F33E2.6	n/a	chrI 12,589,287	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
41	F55E10.2	F55E10.2	n/a	chrX 8,340,780
42	clc-2	C01C10.1	n/a	chrX 7,432,451	clc-2 encodes a claudin homolog, closely similar to CLC-1, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-2 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the hypodermis to dyes; clc-2 is expressed in hypodermal seam cells, with two diffuse lines of CLC-2 protein.
43	F07C3.2	F07C3.2	n/a	chrV 9,226,731
44	fbxa-129	F59A1.8	n/a	chrV 17,656,084	C. elegans FBXA-129 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
45	ZC155.2	ZC155.2	n/a	chrIII 5,219,635	contains similarity to Interpro domains IPR000164 (Histone H3), IPR009072 (Histone-fold)
46	F16B12.4	F16B12.4	n/a	chrX 14,097,334	contains similarity to Dictyostelium discoideum Myosin II heavy chain, non muscle.; SW:MYS2_DICDI
47	tkr-1	C38C10.1	n/a	chrIII 9,386,535	tkr-1 encodes a G protein-coupled receptor that is the C. elegans tachykinin-like neuropeptide receptor homolog; by homology, TKR-1 is predicted to function in modulation of excitatory neurotransmission; as loss of tkr-1 activity via RNAi results in moderate reduction of fat content, TKR-1 may play a specific role in regulating lipid metabolism; a tkr-1 reporter gene fusion is reportedly expressed in the socket cells of the deirid and post-deirid sensilla from the L2 larval stage through adulthood.
48	sdz-23	F58G4.4	n/a	chrV 8,100,032	sdz-23 encodes a putatively secreted protein with a single EGF domain, with some similarity to LAG-2; sdz-23 begins to be expressed in the E blastomere of 8-cell embryos, and continues to be expressed solely in the E lineage througout embryogenesis; sdz-23 requires SKN-1 and WRM-1 for E lineage expression, and is a putative MED-1/2 target gene; sdz-23 is both activated by POP-1 (with SYS-1 as coactivator, in the E lineage) and repressed by POP-1 (in the MS lineage), while the dependence of sdz-23 on WRM-1 for E lineage expression is alleviated by loss of POP-1, indicating that WRM-1 switches POP-1 from repression to activation in the E lineage; sdz-23 requires SYS-1 for normal embryonic expression; SDZ-23 has no obvious function in mass RNAi assays.
49	srt-26	C24B9.2	n/a	chrV 2,716,136	C. elegans SRT-26 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
50	T26E3.8	T26E3.8	n/a	chrI 12,658,593	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)