UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cyp-35C1	C06B3.3	0	chrV 13,897,551	C. elegans CYP-35C1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	eft-1	ZK328.2	n/a	chrIII 6,011,147	eft-1 encodes an elongation factor 2 (EF-2)-like protein; by homology, EFT-1 is predicted to function as a GTPase required for the elongation step of protein synthesis; loss of eft-1 activity via large-scale RNAi indicates that eft-1 is an essential gene required for embryonic development, reproduction, and the overall health of the animal; eft-1 mRNA is detectable at all stages of C. elegans development.
4	F59B8.2	F59B8.2	n/a	chrIV 9,439,991	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004790 (Isocitrate dehydrogenase NADP-dependent, eukaryotic), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
5	E04A4.5	E04A4.5	n/a	chrIV 4,744,928	contains similarity to Pfam domain PF02466 Tim17/Tim22/Tim23 family contains similarity to Interpro domains IPR005678 (Mitochondrial import inner membrane translocase, subunit Tim17), IPR003397 (Mitochondrial import inner membrane translocase, subunit Tim17/22)
6	F11C1.3	F11C1.3	n/a	chrX 12,983,754	contains similarity to Pfam domain PF01130 CD36 family contains similarity to Interpro domain IPR002159 (CD36 antigen)
7	dap-3	C14A4.2	n/a	chrII 10,581,748	dap-3 is an ortholog of mammalian death-associated protein 3 (DAP3), a mitochondrial ribosomal protein that promotes apoptosis.
8	pfd-3	T06G6.9	n/a	chrI 12,729,010	pfd-3 encodes a putative prefoldin, orthologous to human VBP1 (OMIM:300133), that is required for normal alpha-tubulin synthesis, microtubule growth, mitotic spindle formation and positioning, early embryonic cell division, and embryonic and larval viability; PFD-3 is expressed cytoplasmically in most, if not all, tissues.
9	ZK1127.5	ZK1127.5	n/a	chrII 7,051,269	contains similarity to Pfam domains PF01137 (RNA 3'-terminal phosphate cyclase) , PF05189 (RNA 3'-terminal phosphate cyclase (RTC), insert domain) contains similarity to Interpro domains IPR016443 (RNA 3'-terminal phosphate cyclase-like, eukaryotic), IPR013796 (RNA 3'-terminal phosphate cyclase, insert region), IPR000228 (RNA 3'-terminal phosphate cyclase), IPR013792 (RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)
10	dnj-11	F38A5.13	n/a	chrIV 6,587,011	This gene encodes a protein containing a DnaJ ('J') domain.
11	prp-21	W07E6.4	n/a	chrII 487,633	C. elegans PRP-21 protein; contains similarity to Pfam domains PF00240 (Ubiquitin family) , PF01805 (Surp module) (2)contains similarity to Interpro domains IPR000061 (SWAP/Surp), IPR000626 (Ubiquitin)
12	C18E9.5	C18E9.5	n/a	chrII 8,970,895	contains similarity to Turkey herpesvirus LORF11.; TR:Q9IBS2
13	F59A3.3	F59A3.3	n/a	chrI 5,506,231	contains similarity to Pfam domain PF00467 KOW motif contains similarity to Interpro domains IPR005825 (Ribosomal protein L24/L26, conserved site), IPR008991 (Translation protein SH3-like), IPR005824 (KOW), IPR003256 (Ribosomal protein L24)
14	T23B12.2	T23B12.2	n/a	chrV 8,468,082	contains similarity to Pfam domain PF00573 Ribosomal protein L4/L1 family contains similarity to Interpro domains IPR013005 (Ribosomal protein L4/L1e, bacterial-type), IPR002136 (Ribosomal protein L4/L1e)
15	nud-1	F53A2.4	n/a	chrIII 13,341,947	nud-1 encodes the C. elegans ortholog of the Aspergillus nidulans nudC, which mediates nuclear migration along Aspergillus hyphae.
16	F53E10.6	F53E10.6	n/a	chrV 2,602,650	contains similarity to Pfam domain PF07890 Rrp15p contains similarity to Interpro domain IPR012459 (Protein of unknown function DUF1665)
17	spt-5	K08E4.1	n/a	chrIV 12,053,606	C. elegans SPT-5 protein; contains similarity to Pfam domains PF03439 (Supt5 repeat) (2), PF00467 (KOW motif) contains similarity to Interpro domains IPR005100 (Supt5 repeat), IPR008991 (Translation protein SH3-like), IPR003257 (Transcription antitermination protein, NusG, archaea), IPR005824 (KOW), IPR017071 (Transcription elongation factor Spt5), IPR006645 (Transcription antitermination protein, NusG, N-terminal)
18	xpo-3	C49H3.10	n/a	chrIV 7,920,396	imb-6 encodes an importin-beta-like protein orthologous to vertebrate Exportin-t, a specific mediator of tRNA export from the nucleus; IMB-6 is predicted to function by binding tRNAs directly in the presence of the RAN-1 GTPase and facilitating their nucleocytoplasmic transport; in C. elegans, loss of imb-6 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities.
19	math-18	C40A11.1	n/a	chrII 2,154,617	C. elegans MATH-18 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
20	T25D3.2	T25D3.2	n/a	chrII 155,462	contains similarity to Mus musculus 39S ribosomal protein L28, mitochondrial precursor (L28mt) (MRP-L28).; SW:Q9D1B9
21	C18D11.3	C18D11.3	n/a	chrIII 11,823,825	contains similarity to Homo sapiens Transcription factor MLL UPN95022; TR:Q86YN8
22	F55A3.7	F55A3.7	n/a	chrI 10,786,484	contains similarity to Pfam domain PF08644 FACT complex subunit (SPT16/CDC68) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR013953 (FACT complex subunit Spt16p/Cdc68p)
23	tag-210	W08E3.3	n/a	chrI 13,342,122	C. elegans TAG-210 protein; contains similarity to Pfam domains PF01926 (GTPase of unknown function) , PF06071 (Protein of unknown function (DUF933)) contains similarity to Interpro domains IPR012675 (Beta-grasp fold, ferredoxin-type), IPR013029 (Protein of unknown function DUF933), IPR004396 (Conserved hypothetical protein CHP00092), IPR002917 (GTP-binding protein, HSR1-related), IPR012676 (TGS-like), IPR006073 (GTP1/OBG)
24	pfd-1	C08F8.1	n/a	chrIV 11,150,492	pfd-1 encodes a putative prefoldin subunit 1, orthologous to human PFDN1 (OMIM:604897), that is required for normal microtubule nucleation and growth, embryonic viability, distal tip cell (DTC) migration, and locomotion; PFD-1 is expressed cytoplasmically in most, if not all, tissues; pfd-1(RNAi) animals have sterile progeny and are uncoordinated, and pfd-1(RNAi) embryos show a reduced microtubule growth rate; pfd-1(gk526) or escaper pfd-1(RNAi) hermaphrodites exhibit detective DTC migration.
25	R74.7	R74.7	n/a	chrIII 4,205,094	contains similarity to Pfam domain PF01728 FtsJ-like methyltransferase contains similarity to Interpro domains IPR015507 (Ribosomal RNA methyltransferase J), IPR002877 (Ribosomal RNA methyltransferase RrmJ/FtsJ)
26	gex-3	F28D1.10	n/a	chrIV 12,406,527	The gex-3 gene encodes a homolog of NAP1/NCKAP1, a mammalian protein ligand of the small GTPase Rac1, and of Drosophila HEM2/NAP1/KETTE; gex-3 is required for tissue morphogenesis and cell migrations; in gex-3 mutants, cells differentiate properly but fail to become organized.
27	npp-15	C29E4.4	n/a	chrIII 7,930,950	C. elegans NPP-15 protein; contains similarity to Pfam domains PF08801 (Nup133 N terminal like) , PF04044 (Nup133 nucleoporin) contains similarity to Interpro domains IPR014908 (Nup133, N-terminal), IPR015943 (WD40/YVTN repeat-like), IPR007187 (Nucleoporin, Nup133-like, C-terminal)
28	stdh-3	C06B3.5	n/a	chrV 13,905,299	stdh-3 encodes a putative steroid dehydrogenase orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767, STDH-1/-2, and STDH-4; STDH-3 has no obvious function in mass RNAi assays.
29	arl-1	F54C9.10	n/a	chrII 8,582,264	arl-1 encodes a member of the GTP-binding ADP-ribosylation factor family.
30	E02H1.6	E02H1.6	n/a	chrII 9,597,035	E02H1.6 encodes an ortholog of human TAF9 (OMIM:600822; also known as AK6, adrenal gland protein AD-004 like protein, ADLP) and of S. cerevisiae Fap7p; like its human ortholog, E02H1.6 is nuclear, and is predicted to likewise be a TATA box binding protein (TBP)-associated factor mediating activation of RNA polymerase II; E02H1.6 prefers ATP and dATP as phosphate donors; E02H1.6's biochemical activity is unusual, since it also prefers AMP and dAMP as substrates, and tolerates CMP, TMP and shikimate acid as substrates as well; since yeast Fap7p promotes pre-rRNA cleavage, E02H1.6 may be multifunctional; in RNAi assays, E02H1.6 is required for normally fast growth; E02H1.6 is coexpressed with pme-2 in an operon, and thus, like PME-2, may function in DNA repair.
31	H19N07.1	H19N07.1	n/a	chrV 11,111,736	contains similarity to Pfam domains PF03143 (Elongation factor Tu C-terminal domain) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) contains similarity to Interpro domains IPR000795 (Protein synthesis factor, GTP-binding), IPR004160 (Translation elongation factor EFTu/EF1A, C-terminal), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR009001 (Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)
32	mel-46	T06A10.1	n/a	chrIV 16,859,204	C. elegans MEL-46 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
33	F01G4.3	F01G4.3	n/a	chrIV 11,138,937	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF08148 (DSHCT (NUC185) domain) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR016438 (RNA helicase, ATP-dependent, SK12/DOB1), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR012961 (DSH, C-terminal), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
34	cyp-13A11	F14F7.2	1e-16	chrIII 13,022,359	C. elegans CYP-13A11 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
35	ubh-4	C08B11.7	n/a	chrII 8,038,864	C. elegans UBH-4 protein; contains similarity to Pfam domain PF01088 Ubiquitin carboxyl-terminal hydrolase, family 1 contains similarity to Interpro domains IPR001578 (Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1), IPR017390 (Ubiquitinyl hydrolase, UCH37 type)
36	M88.2	M88.2	n/a	chrIII 4,541,915	contains similarity to Aedes aegypti Mitochondrial ribosomal protein, S34, putative.; TR:Q17JQ1
37	ruvb-1	C27H6.2	n/a	chrV 9,979,753	C. elegans RUVB-1 protein; contains similarity to Pfam domain PF06068 TIP49 C-terminus contains similarity to Interpro domains IPR010339 (TIP49, C-terminal), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal)
38	C01G10.10	C01G10.10	n/a	chrV 15,081,298	contains similarity to Pfam domain PF00814 Glycoprotease family contains similarity to Interpro domains IPR009180 (Peptidase M22, O-sialoglycoprotein endopeptidase), IPR000905 (Peptidase M22, glycoprotease)
39	pat-3	ZK1058.2	n/a	chrIII 3,911,515	C. elegans PAT-3 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) , PF00362 (Integrin, beta chain) , PF07965 (Integrin beta tail domain) , PF07974 (EGF-like domain) (2), PF08725 (Integrin beta cytoplasmic domain) contains similarity to Interpro domains IPR002369 (Integrin beta subunit, N-terminal), IPR012896 (Integrin beta subunit, tail), IPR001169 (Integrin beta subunit, C-terminal), IPR006209 (EGF-like), IPR002049 (EGF-like, laminin), IPR015812 (Integrin beta subunit), IPR014836 (Integrin beta subunit, cytoplasmic), IPR003659 (Plexin/semaphorin/integrin), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR012012 (Integrin beta subunit, subgroup), IPR002035 (von Willebrand factor, type A)
40	ZK1236.1	ZK1236.1	n/a	chrIII 8,430,360	contains similarity to Pfam domains PF06421 (GTP-binding protein LepA C-terminus) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) , PF00679 (Elongation factor G C-terminus) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR000795 (Protein synthesis factor, GTP-binding), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR006297 (GTP-binding protein LepA), IPR000640 (Translation elongation factor EFG/EF2, C-terminal), IPR013842 (GTP-binding protein LepA, C-terminal), IPR009022 (Elongation factor G, III and V)
41	F25G6.8	F25G6.8	n/a	chrV 8,564,846	contains similarity to Pfam domain PF02290 Signal recognition particle 14kD protein contains similarity to Interpro domains IPR009018 (Signal recognition particle, SRP9/SRP14 subunit), IPR003210 (Signal recognition particle, SRP14 subunit)
42	scpl-4	T21C9.12	n/a	chrV 10,600,600	scpl-4 encodes an ortholog of budding yeast TIM50 and human TIMM50 (OMIM:607381); by orthology, SCPL-4 is expected to be part of the mitochondrial inner membrane protein translocase; SCPL-4 is required for embryonic development and fertility in mass RNAi assays; SCPL-4 is distantly similar to FCP-1 and SCPL-1, -2, and -3.
43	ZK795.3	ZK795.3	n/a	chrIV 12,559,996	contains similarity to Pfam domain PF04427 Brix domain contains similarity to Interpro domain IPR007109 (Brix)
44	K08F11.5	K08F11.5	n/a	chrIV 4,714,405	contains similarity to Pfam domains PF08356 (EF hand associated) , PF08355 (EF hand associated) , PF00071 (Ras family) , PF00036 (EF hand) (2), PF08477 (Miro-like protein) (2)contains similarity to Interpro domains IPR013566 (EF hand associated, type-1), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily), IPR013567 (EF hand associated, type-2)
45	K11B4.1	K11B4.1	n/a	chrI 14,796,015	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
46	ent-1	ZK809.4	n/a	chrIV 11,654,417	ent-1 encodes a predicted equilibrative nucleoside transporter 1 that affects growth.
47	F53F1.2	F53F1.2	n/a	chrV 13,407,532	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
48	tin-13	DY3.1	n/a	chrI 8,759,490	C. elegans TIN-13 protein; contains similarity to Pfam domain PF02953 Tim10/DDP family zinc finger contains similarity to Interpro domain IPR004217 (Zinc finger, Tim10/DDP-type)
49	nol-10	F32E10.1	n/a	chrIV 7,582,143	C. elegans NOL-10 protein; contains similarity to Pfam domain PF08159 NUC153 domain contains similarity to Interpro domains IPR012580 (NUC153), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
50	T01E8.6	T01E8.6	n/a	chrII 10,241,373	contains similarity to Pfam domain PF00253 Ribosomal protein S14p/S29e contains similarity to Interpro domain IPR001209 (Ribosomal protein S14)