UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C06A12.3	C06A12.3	7e-134	chrIV 17,428,622	contains similarity to Pfam domain PF05303 Protein of unknown function (DUF727) contains similarity to Interpro domain IPR007967 (Protein of unknown function DUF727)
2	fbxa-60	T12B5.10	n/a	chrIII 945,562	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
3	F38A1.9	F38A1.9	n/a	chrIV 1,244,866
4	R07B7.5	R07B7.5	n/a	chrV 12,069,626	contains similarity to Pfam domain PF01494 FAD binding domain contains similarity to Interpro domains IPR003042 (Aromatic-ring hydroxylase), IPR002938 (Monooxygenase, FAD-binding)
5	C29F7.7	C29F7.7	n/a	chrX 13,442,218	contains similarity to Peromyscus maniculatus Alcohol dehydrogenase 2 (EC 1.1.1.1).; SW:ADH2_PERMA
6	F19C7.6	F19C7.6	n/a	chrIV 4,595,282
7	ugt-19	K08B4.3	n/a	chrIV 6,078,341	C. elegans UGT-19 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
8	sri-42	T10D4.9	n/a	chrII 3,141,931	C. elegans SRI-42 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	acl-3	ZK809.2	n/a	chrIV 11,651,359	acl-3 encodes a phosphate acyltransferase that is orthologous to human tafazzin (TAZ; OMIM:300394, mutated in Barth syndrome); by homology, ACL-3 is predicted to be a mitochondrial protein that plays a role in phospholipid metabolism, although loss of acl-3 activity via large-scale RNAi screens results in no obvious defects.
10	K08C7.7	K08C7.7	n/a	chrIV 10,665,006	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
11	F14D7.7	F14D7.7	n/a	chrV 14,306,660	contains similarity to Chlorobium tepidum Peptidyl-prolyl cis-trans isomerase, PpiC-type.; TR:Q8KFW7
12	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
13	Y12A6A.1	Y12A6A.1	n/a	chrX 13,620,760
14	srw-88	T06G6.7	n/a	chrI 12,721,084	C. elegans SRW-88 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
15	C12D12.5	C12D12.5	n/a	chrX 3,505,953	contains similarity to Pfam domain PF00505 HMG (high mobility group) box contains similarity to Interpro domains IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG)
16	unc-31	ZK897.1	n/a	chrIV 12,780,334	unc-31 encodes a pleckstrin homology (PH) domain-containing protein that is the C. elegans ortholog of human CADPS/CAPS (calcium-dependent activator protein for secretion OMIM:604667); UNC-31 functions in post-docking calcium-regulated dense-core vesicle fusion that is required for egg laying, locomotion, pharyngeal pumping, and recovery from the dauer larval stage; in addition, UNC-31 functions in the insulin receptor signaling pathway that regulates adult life span where it may control Ca[2+]-regulated secretion of an insulin-like ligand; UNC-31 is not required for synaptic vesicle exocytosis; unc-31::gfp transcriptional reporters are expressed in most, if not all, neurons, vulval muscles, vulval cells, the spermatheca, and secretory cells such as the uterine UV1 cells; UNC-31::GFP translational fusions localize to neuronal cell bodies, axonal projections and to sites of synaptic contact, consistent with other dense-core vesicle proteins.
17	cka-1	C28D4.2	n/a	chrIV 9,734,654	cka-1 encodes an isoform of choline kinase whose activity has been verified in vitro, and that has a strong preference for choline over ethanolamine; CKA-1 and CKA-2 comprise a related group ('A') of choline kinases.
18	srh-181	ZK228.6	n/a	chrV 18,475,360	C. elegans SRH-181 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	R105.1	R105.1	n/a	chrIV 4,635,811	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
20	B0244.7	B0244.7	n/a	chrIII 5,732,127	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
21	C44C8.2	C44C8.2	n/a	chrIV 900,230
22	C30H6.7	C30H6.7	n/a	chrIV 17,381,384	contains similarity to Pfam domains PF00198 (2-oxoacid dehydrogenases acyltransferase (catalytic domain)) , PF02817 (e3 binding domain) contains similarity to Interpro domains IPR004167 (E3 binding), IPR001078 (Catalytic domain of components of various dehydrogenase complexes)
23	clec-144	T27D12.3	n/a	chrII 11,831,976	C. elegans CLEC-144 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
24	M02F4.2	M02F4.2	n/a	chrX 3,033,806
25	his-65	H02I12.7	n/a	chrIV 11,401,254	his-65 encodes an H2A histone.
26	ZK829.7	ZK829.7	n/a	chrIV 11,960,692	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
27	K07A12.1	K07A12.1	n/a	chrI 8,668,182	contains similarity to Pfam domain PF04910 Protein of unknown function, DUF654 contains similarity to Interpro domains IPR006994 (Basic helix-loop-helix, Nulp1-type), IPR000294 (Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)
28	Y106G6H.8	Y106G6H.8	n/a	chrI 10,452,513	contains similarity to Pfam domain PF04241 Protein of unknown function (DUF423) contains similarity to Interpro domain IPR006696 (Protein of unknown function DUF423)
29	F45E4.11	F45E4.11	n/a	chrIV 7,652,864	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
30	C53D6.7	C53D6.7	n/a	chrIV 9,035,988	contains similarity to Pfam domain PF00337 Galactoside-binding lectin contains similarity to Interpro domains IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
31	wts-1	T20F10.1	n/a	chrI 10,294,898	C. elegans WTS-1 protein; contains similarity to Pfam domains PF00069 (Protein kinase domain) , PF00433 (Protein kinase C terminal domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000694 (Proline-rich region), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
32	F22H10.6	F22H10.6	n/a	chrX 16,690,126
33	nspb-5	F38A5.9	n/a	chrIV 6,599,329	C. elegans NSPB-5 protein; contains similarity to Pfam domain PF07312 Protein of unknown function (DUF1459) contains similarity to Interpro domain IPR009924 (Protein of unknown function DUF1459)
34	W03H9.2	W03H9.2	n/a	chrII 14,144,403	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000046554
35	C49C3.10	C49C3.10	n/a	chrIV 17,337,847	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000215 (Protease inhibitor I4, serpin), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
36	C49A9.2	C49A9.2	n/a	chrIV 6,226,732	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
37	R10E8.2	R10E8.2	n/a	chrV 18,254,063	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
38	C32E8.9	C32E8.9	n/a	chrI 3,796,306	contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
39	kin-4	C10C6.1	n/a	chrIV 11,441,819	C. elegans KIN-4 protein; contains similarity to Pfam domains PF08926 (Domain of unknown function (DUF1908)) , PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR015022 (Region of unknown function DUF1908), IPR000719 (Protein kinase, core), IPR001478 (PDZ/DHR/GLGF), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
40	K08E4.4	K08E4.4	n/a	chrIV 12,066,699	contains similarity to Entamoeba histolytica Pyruvate,phosphate dikinase (EC 2.7.9.1) (Pyruvate,orthophosphatesdikinase).; SW:PODK_ENTHI
41	F20D12.2	F20D12.2	n/a	chrIV 7,951,094	contains similarity to Pfam domain PF03399 SAC3/GANP/Nin1/mts3/eIF-3 p25 family contains similarity to Interpro domain IPR005062 (SAC3/GANP/Nin1/mts3/eIF-3 p25)
42	C10A4.7	C10A4.7	n/a	chrX 7,414,514
43	gcy-8	C49H3.1	n/a	chrIV 7,930,918	gcy-8 encodes a receptor-type guanylyl cyclase that, along with gcy-18 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-8 functions redundantly with gcy-18 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; GCY-8 is expressed exclusively in the AFD thermosensory neurons where it localizes to sensory endings; GCY-8 expression in the AFD neurons requires activity of the TAX-2/4 cyclic nucleotide gated channel and the CMK-1 Ca2+/calmodulin-dependent protein kinase I, while maintenance of GCY-8 expression requires the OTD/OTX homeodomain protein TTX-1.
44	T25G12.3	T25G12.3	n/a	chrX 17,234,022
45	F46C5.7	F46C5.7	n/a	chrII 8,839,705	contains similarity to Homo sapiens Splice isoform 1 of Q8WXQ8 Carboxypeptidase A5 precursor; ENSEMBL:ENSP00000289573
46	gtl-1	C05C12.3	n/a	chrIV 11,254,145	gtl-1 encodes a TRPM subfamily member of the TRP channel family that affects the periodicity of the defecation cycle in combination with gon-2; expression includes the intestine.
47	srw-58	H24D24.2	n/a	chrV 15,947,853	C. elegans SRW-58 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)
48	ZK550.2	ZK550.2	n/a	chrIV 17,247,626	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
49	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
50	T28F3.9	T28F3.9	n/a	chrIV 17,310,065	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)