UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	str-262	C05E4.13	1e-178	chrV 752,054	C. elegans STR-262 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
2	F31E3.6	F31E3.6	n/a	chrIII 6,982,722
3	ZK673.4	ZK673.4	n/a	chrII 10,453,965	ZK673.4 encodes a protein with a THAP or THAP-like domain; other proteins with such domains include LIN-15A, LIN-15B, LIN-36, and HIM-17 (which all interact with LIN-35/Rb), as well as CDC-14B, CTB-1, GON-14, and ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1.
4	C15B12.2	C15B12.2	n/a	chrX 6,464,379
5	T14B4.8	T14B4.8	n/a	chrII 6,720,967
6	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
7	F32B4.8	F32B4.8	n/a	chrI 11,504,367	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN)
8	T25C8.1	T25C8.1	n/a	chrIII 13,611,268	contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000577 (Carbohydrate kinase, FGGY)
9	grl-23	E02A10.2	n/a	chrV 12,576,078	grl-23 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a glycine-rich low-complexity region, a Ground-like (Grl) domain, and an acid-rich low-complexity region; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
10	fbxa-215	Y45F10C.3	n/a	chrIV 13,666,087	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
11	W03F11.1	W03F11.1	n/a	chrI 2,220,892	W03F11.1 encodes a protein with three chitin-binding peritrophin-A domains; like CEJ-1 and CPG-2, W03F11.1 may participate in eggshell synthesis and early embryonic development; W03F11.1 is required for fertility in mass RNAi assays; W03F11.1's multiple peritrophin-A domains might enable mechanical cross-linking of chitin.
12	D1086.7	D1086.7	n/a	chrV 14,084,866	contains similarity to Synechocystis sp Hypothetical protein slr1028.; TR:P73139
13	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
14	btb-7	F45C12.12	n/a	chrII 1,713,745	C. elegans BTB-7 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
15	C11D2.1	C11D2.1	n/a	chrIV 6,191,401
16	srh-193	F47D2.9	n/a	chrV 4,289,288	C. elegans SRH-193 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	fbxb-48	F45C12.13	n/a	chrII 1,718,632	C. elegans FBXB-48 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
18	C05D11.8	C05D11.8	n/a	chrIII 6,424,823	contains similarity to Homo sapiens Isoform 2 of UPF0518 protein C11orf56; ENSEMBL:ENSP00000265978
19	ttr-2	K03H1.4	n/a	chrIII 9,928,259	K03H1.4 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of K03H1.4 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
20	B0304.4	B0304.4	n/a	chrII 4,522,834
21	mex-6	AH6.5	n/a	chrII 9,525,192	mex-6 encodes a CCCH zinc-finger protein highly similar to MEX-5 that functions with MEX-5 to affect embryonic viability, establish soma germline asymmetry in embryos and establish PIE-1, MEX-1, and POS-1 asymmetry in embryos, and also affects formation of intestinal cells; MEX-6 and MEX-5 may act downstream of the PAR proteins.
22	Y6E2A.4	Y6E2A.4	n/a	chrV 15,713,920	contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
23	F35E8.13	F35E8.13	n/a	chrV 15,925,673	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
24	C43F9.4	C43F9.4	n/a	chrIV 10,588,322
25	F32D8.3	F32D8.3	n/a	chrV 10,887,380	F32D8.3 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; F32D8.3 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; F32D8.3 has no obvious function in mass RNAi assays.
26	ceh-8	ZK265.4	n/a	chrI 8,248,368	ceh-8 encodes a paired-like homeodomain protein of the Q50 class orthologous to the Rx homeobox protein of humans (RAX; OMIM:601881) and Drosophila (CG10052-PA); CEH-8 and RX belong to one of at least 18 distinct families of paired-like homeodomain proteins, including 12 families in the Q50 class.
27	twk-2	T12C9.3	n/a	chrII 4,447,199	twk-2 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-2 in C. elegans development and/or behavior is not yet known, but TWK-2 may function redundantly with other TWK channels; TWK-2 is expressed in a subset of neurons.
28	srz-100	T25E12.11	n/a	chrV 16,732,494	C. elegans SRZ-100 protein ;
29	C05D11.13	C05D11.13	n/a	chrIII 6,443,485	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
30	F58H7.5	F58H7.5	n/a	chrIV 920,399
31	B0284.1	B0284.1	n/a	chrIII 4,377,822	contains similarity to Interpro domain IPR016027 (Nucleic acid-binding, OB-fold-like)
32	C07D10.1	C07D10.1	n/a	chrII 7,399,714	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
33	tag-199	F45E4.4	n/a	chrIV 7,612,783	C. elegans TAG-199 protein ; contains similarity to Trypanosoma brucei Putative uncharacterized protein.; TR:Q4GZ45
34	nhr-18	F44C8.3	n/a	chrV 2,228,092	The nhr-18 gene encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain; the human homolog of nhr-18, CYP21, when mutated leads to congenital adrenal hyperplasia (OMIM:201910).
35	K08E4.2	K08E4.2	n/a	chrIV 12,056,130	contains similarity to Pfam domain PF08718 Glycolipid transfer protein (GLTP) contains similarity to Interpro domain IPR014830 (Glycolipid transfer protein, GLTP)
36	spp-20	K04A8.8	n/a	chrV 6,557,433	C. elegans SPP-20 protein; contains similarity to Pfam domain PF05184 Saposin-like type B, region 1 contains similarity to Interpro domains IPR011001 (Saposin-like), IPR007856 (Saposin-like type B, 1), IPR008139 (Saposin B)
37	ttr-5	C40H1.5	n/a	chrIII 9,330,525	C40H1.5 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of C40H1.5 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
38	T26H5.8	T26H5.8	n/a	chrV 15,429,911	contains similarity to Pfam domains PF04789 (Protein of unknown function (DUF621)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR006874 (Protein of unknown function DUF621)
39	srx-56	C03G6.2	n/a	chrV 7,374,979	C. elegans SRX-56 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
40	ocr-3	T10B10.7	n/a	chrX 15,171,101	ocr-3 encodes a predicted TRPV channel (transient receptor potential cation channel, subfamily V) containing six membrane-spanning regions, cytoplasmic ankyrin repeats, and a long, unconserved cytoplasmic tail that is related to the mammalian TRPV1 cation channel (OMIM:602076) activated by capsaicin and other noxious stimuli; although the precise role of OCR-3 in C. elegans development and/or behavior is not yet known, OCR-3 expression is detected solely in the rectal gland cells and occasionally the glial socket cells of the head, suggesting that OCR-3 may function in sensory signal transduction in these cell types.
41	F57A10.4	F57A10.4	n/a	chrV 15,769,845	contains similarity to Oceanobacillus iheyensis Alkaliphily related protein.; TR:Q8EQ12
42	ugt-18	ZC443.5	n/a	chrV 12,821,489	C. elegans UGT-18 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
43	ref-1	T01E8.2	n/a	chrII 10,219,169	ref-1 encodes a protein with two basic helix-loop-helix (bHLH) domains that is distantly related to the hairy/Enhancer of split subfamily of bHLH transcription factors; REF-1 is required in hermaphrodites during early larval development for regulating the pattern of posterior Pn.p hypodermal cell fusions, primarily through regulation of MAB-5 homeodomain protein activity; REF-1 is also required for head morphogenesis and specification of the V6 lateral seam cell fate; in males, ref-1 is a target of MAB-3 transcriptional repression which in turn, promotes expression of LIN-32, a proneural bHLH transcription factor.
44	F53F4.4	F53F4.4	n/a	chrV 13,596,162	contains similarity to Candida albicans Chitinase 3 precursor (EC 3.2.1.14).; SW:CHI3_CANAL
45	C03G6.6	C03G6.6	n/a	chrV 7,358,148	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
46	F32D8.2	F32D8.2	n/a	chrV 10,884,916	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domain IPR004245 (Protein of unknown function DUF229)
47	F47B8.6	F47B8.6	n/a	chrV 14,329,569	contains similarity to Drosophila heteroneura Aminopeptidase N (Fragment).; TR:O61534
48	pqn-73	W01C9.3	n/a	chrII 8,543,297	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
49	col-37	ZK863.2	n/a	chrV 12,167,206	col-37 encodes a cuticle collagen.
50	F48G7.2	F48G7.2	n/a	chrV 637,034