UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	snx-1	C05D9.1	0	chrX 1,130,709	C. elegans SNX-1 protein; contains similarity to Pfam domains PF09325 (Vps5 C terminal like) , PF00787 (PX domain) contains similarity to Interpro domains IPR001683 (Phox-like), IPR013822 (Signal recognition particle, SRP54 subunit, helical bundle), IPR015404 (Vps5 C terminal like)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F08B12.1	F08B12.1	n/a	chrX 11,388,875	F08B12.1 is orthologous to the human gene AC133-2 ANTIGEN (PROML1; OMIM:604365), which when mutated leads to disease.
4	ZK470.6	ZK470.6	n/a	chrX 4,176,765
5	rer-1	F46C5.8	n/a	chrII 8,811,744	C. elegans RER-1 protein; contains similarity to Pfam domain PF03248 Rer1 family contains similarity to Interpro domain IPR004932 (Retrieval of early ER protein Rer1)
6	rab-11.1	F53G12.1	n/a	chrI 109,369	rab-11.1 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; RAB-11.1 activity is required for completion of the final stages of cytokinesis during early embryogenesis and for efficient uptake of yolk proteins during oocyte development; RAB-11.1 is also required for normal peripheral localization of nuclei in the synctial germ cell in the ovary.
7	R08D7.7	R08D7.7	n/a	chrIII 8,993,437	contains similarity to Pfam domains PF02782 (FGGY family of carbohydrate kinases, C-terminal domain) , PF00370 (FGGY family of carbohydrate kinases, N-terminal domain) contains similarity to Interpro domain IPR000577 (Carbohydrate kinase, FGGY)
8	gpr-2	C38C10.4	n/a	chrIII 9,392,118	gpr-2 encodes a protein containing a GPR (G Protein Regulator)/GoLoco motif characteristic of guanine nucleotide exchange factors specific for G-alpha GTPases; GPR-2 appears to function redundantly during early embryogenesis and germ-line development to regulate chromosome and spindle movements during cell division; GPR-2 likely acts as a positive regulator of G protein signaling and specifically, may regulate GOA-1 signaling in the embryo; GPR-2 forms a protein complex with the nearly identical GPR-1 and with LIN-5, a coiled-coil protein that is required for proper localization of GPR-2 to the cell cortex and spindle asters of the early embryo; in addition, proper GPR-2/GPR-1/LIN-5 localization between the P2 and EMS blastomeres at the four-cell stage, which may contribute to spindle positioning in EMS, requires the MES-1/SRC-1 tyrosine kinase signaling pathway; GPR-2 is believed to act downstream of, or in parallel to, PAR-3, a PDZ domain-containing protein, in mitotic spindle positioning in the early embryo.
9	K04C1.4	K04C1.4	n/a	chrX 14,246,093	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
10	T16G1.2	T16G1.2	n/a	chrV 12,931,137	contains similarity to Interpro domain IPR000694 (Proline-rich region)
11	C16C8.2	C16C8.2	n/a	chrII 3,433,889	contains similarity to Pfam domains PF01549 (ShK domain-like) (2), PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal), IPR003582 (Metridin-like ShK toxin)
12	ZC504.3	ZC504.3	n/a	chrX 10,418,158	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
13	sgcb-1	K01A2.1	n/a	chrII 327,229	K01A2.1 is orthologous to the human gene SARCOGLYCAN, BETA (43KD DYSTROPHIN-ASSOCIATED GLYCOPROTEIN) (SGCB; OMIM:600900), which when mutated leads to disease.
14	F16G10.7	F16G10.7	n/a	chrII 2,379,927	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
15	inx-15	R12E2.9	n/a	chrI 4,160,065	C. elegans INX-15 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
16	F13D2.1	F13D2.1	n/a	chrX 11,169,479	contains similarity to Interpro domain IPR008930 (Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)
17	F25B4.5	F25B4.5	n/a	chrV 5,680,736	contains similarity to Interpro domain IPR003107 (RNA-processing protein, HAT helix)
18	C34C12.6	C34C12.6	n/a	chrIII 3,483,701	contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
19	F11E6.8	F11E6.8	n/a	chrIV 17,447,304	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
20	fce-1	C04F12.10	n/a	chrI 9,711,884	fce-1 encodes an ortholog of 'farnesylated-proteins converting enzyme 1' (FACE-1), and thus probably enables post-translational processing of proteins (such as LET-60/RAS) carrying a C-terminal CaaX motif; FCE-1 protein probably accounts for the EDTA-sensitive, tosylphenylalanylchloromethane-insensitive component of CaaX-proteolytic activity in membrane extracts from C. elegans, and FCE-1 can cleave a farnesylated peptide in vitro; the S. cerevisiae homolog of FCE-1 (Ste24p) cleaves the precursor of yeast a-factor mating pheromone after its farnesylated cysteine residue, and transgenic FCE-1 rescues a mating defect of mutant yeast lacking both the Ste24p and the Rce1p CaaX-proteases.
21	sulp-3	F41D9.5	n/a	chrX 8,405,893	sulp-3 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-3 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-3::GFP transcriptional fusion is expressed exclusively in the pharyngeal muscles.
22	F42A10.5	F42A10.5	n/a	chrIII 6,172,231	contains similarity to Interpro domain IPR003072 (Orphan nuclear receptor, NOR1 type)
23	dpy-1	M01E10.2	n/a	chrIII 2,041,006	dpy-1 encodes a collagen that affects body length and alae formation; site of action localized to the hyp7 syncytium, based on mosaic analysis.
24	C13C12.2	C13C12.2	n/a	chrV 12,524,627	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
25	F55C5.8	F55C5.8	n/a	chrV 12,290,267	contains similarity to Drosophila melanogaster Flybase gene name is Srp68-PA;; FLYBASE:CG5064
26	Y11D7A.8	Y11D7A.8	n/a	chrIV 9,252,608	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
27	fli-1	B0523.5	n/a	chrIII 8,679,606	fli-1 encodes a homolog of Drosophila flightless-I; can interact with human Ha-Ras and human actin in vitro; mRNA levels are highest in embryos.
28	E01G6.1	E01G6.1	n/a	chrX 12,263,633	contains similarity to Pfam domains PF00027 (Cyclic nucleotide-binding domain) (2), PF01734 (Patatin-like phospholipase) contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin), IPR000595 (Cyclic nucleotide-binding), IPR001423 (Lysophospholipase patatin, conserved site), IPR014710 (RmlC-like jelly roll fold)
29	ptr-6	C54A12.1	n/a	chrII 5,244,628	ptr-6 encodes an ortholog of Drosophila and human PTCHD3, which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTR-6 is weakly required for normal molting from L4 to adult stages; however, PTR-6 in conjunction with PTR-1 and PTR-10 is strongly required for both molting and viability, with triple ptr-1/-6/-10 RNAi animals showing pronounced molting defects and lethality; PTR-6 is also required for normal growth to full size and locomotion.
30	F59F4.3	F59F4.3	n/a	chrX 15,844,928	contains similarity to Interpro domain IPR002038 (Osteopontin)
31	C04E12.12	C04E12.12	n/a	chrV 3,390,139	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
32	tap-1	C44H4.5	n/a	chrX 14,590,650	C. elegans TAP-1 protein; contains similarity to Pfam domain PF00481 Protein phosphatase 2C contains similarity to Interpro domains IPR001932 (Protein phosphatase 2C-related), IPR014045 (Protein phosphatase 2C, N-terminal), IPR015655 (Protein phosphatase 2C)
33	F38A1.8	F38A1.8	n/a	chrIV 1,236,362	contains similarity to Pfam domains PF00448 (SRP54-type protein, GTPase domain) , PF02881 (SRP54-type protein, helical bundle domain) , PF04086 (Signal recognition particle, alpha subunit, N-terminal) contains similarity to Interpro domains IPR007222 (Signal recognition particle receptor, alpha subunit, N-terminal), IPR000897 (Signal recognition particle, SRP54 subunit, GTPase), IPR011012 (Longin-like), IPR013822 (Signal recognition particle, SRP54 subunit, helical bundle), IPR003593 (AAA+ ATPase, core)
34	mab-10	R166.1	n/a	chrII 10,532,058	C. elegans MAB-10 protein; contains similarity to Pfam domains PF04905 (NAB conserved region 2 (NCD2)) , PF04904 (NAB conserved region 1 (NCD1)) contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR006988 (Nab, N-terminal), IPR006989 (Nab, central region)
35	K02B12.3	K02B12.3	n/a	chrI 8,510,282	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
36	BE10.2	BE10.2	n/a	chrIII 12,795,671	contains similarity to Homo sapiens Transmembrane protein 195; ENSEMBL:ENSP00000341662
37	F53G2.3	F53G2.3	n/a	chrII 2,480,856
38	lst-2	R160.7	n/a	chrX 4,380,673	C. elegans LST-2 protein; contains similarity to Pfam domain PF01363 FYVE zinc finger contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
39	F46C5.9	F46C5.9	n/a	chrII 8,809,612	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
40	inx-4	F26D11.10	n/a	chrV 7,963,664	C. elegans INX-4 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
41	C05E11.7	C05E11.7	n/a	chrX 4,583,603
42	H13N06.2	H13N06.2	n/a	chrX 15,489,935	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)
43	ubh-1	F46E10.8	n/a	chrV 6,510,664	ubh-1 encodes a putative ubiquitin C-terminal hydrolase orthologous to human UCHL1 (OMIM:191342, mutated in Parkinson disease).
44	C34C12.8	C34C12.8	n/a	chrIII 3,460,983	contains similarity to Pfam domain PF01025 GrpE contains similarity to Interpro domains IPR009012 (GrpE nucleotide exchange factor, head), IPR013805 (GrpE nucleotide exchange factor, coiled-coil), IPR000740 (GrpE nucleotide exchange factor)
45	F35D2.1	F35D2.1	n/a	chrII 7,577,252
46	ctg-2	T13H5.2	n/a	chrII 8,515,897	C. elegans CTG-2 protein; contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001071 (Cellular retinaldehyde binding/alpha-tocopherol transport), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
47	F30H5.3	F30H5.3	n/a	chrIII 508,704	contains similarity to Pfam domains PF01683 (EB module) (3), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (5)contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR008197 (Whey acidic protein, 4-disulphide core), IPR006150 (Cysteine-rich repeat), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR006149 (Nematode-specific EB region)
48	ugt-53	T03D3.1	n/a	chrV 2,850,684	C. elegans UGT-53 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domains IPR002416 (Bacterial general secretion pathway protein H), IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
49	T18D3.3	T18D3.3	n/a	chrX 12,465,679	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domains IPR002524 (Cation efflux protein), IPR000425 (Major intrinsic protein)
50	nsy-1	F59A6.1	n/a	chrII 5,026,357	nsy-1 encodes a MAP kinase kinase kinase homolog that affects chemotaxis, egg laying, and pathogen response; NSY-1 activity is activated by the calmodulin kinase UNC-43, and is required for lateral signalling that leads to asymmetric olfactory neuron fates; interacts with SEK-1, and is expressed in the intestine, hypodermis, rectal gland cells, and neurons.