UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C05D11.5	C05D11.5	2e-153	chrIII 6,410,742	contains similarity to Pfam domain PF01261 Xylose isomerase-like TIM barrel contains similarity to Interpro domains IPR013279 (Apoptosis regulator, Bcl-X), IPR012307 (Xylose isomerase-type TIM barrel), IPR013022 (Xylose isomerase-like, TIM barrel)
2	T23D8.3	T23D8.3	n/a	chrI 9,974,837	T23D8.3 encodes an ortholog of yeast and human LTV1 that inhibits DHC-1 in vivo; in mass RNAi assays, T23D8.3 is required for embryonic and larval development, normally large brood sizes, and normally fast growth.
3	nhr-36	F07C3.10	n/a	chrV 9,258,968	C. elegans NHR-36 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF01461 (7TM chemoreceptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR003002 (7TM chemoreceptor, subfamily 1), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	F35C11.6	F35C11.6	n/a	chrII 8,258,607	contains similarity to Homo sapiens Oxysterol binding protein-related protein 11; ENSEMBL:ENSP00000296220
5	T26F2.2	T26F2.2	n/a	chrV 13,982,237	contains similarity to Homo sapiens Isoform 1 of Protein Dom3Z; ENSEMBL:ENSP00000337759
6	C34F6.7	C34F6.7	n/a	chrX 11,212,716	contains similarity to Drosophila melanogaster Flybase gene name is CG14646-PA;; FLYBASE:CG14646
7	F56F10.2	F56F10.2	n/a	chrX 861,193	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
8	T08B6.2	T08B6.2	n/a	chrIV 4,895,590
9	srsx-32	F20A1.3	n/a	chrV 7,018,087	C. elegans SRSX-32 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
10	sra-1	AH6.4	n/a	chrII 9,520,857	sra-1 encodes a predicted seven transmembrane receptor; expressed in the male SPD and SPV neurons.
11	str-224	K10C9.8	n/a	chrV 1,057,769	C. elegans STR-224 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	dgk-5	K06A1.6	n/a	chrII 6,462,041	dgk-5 encodes a putative diacylglycerol kinase, orthologous to Drosophila RDGA, and to human DGKI (OMIM:604072) and DGKZ (OMIM:601441); DGK-5 has no obvious function in mass RNAi assays.
13	orai-1	C09F5.2	n/a	chrIII 653,677	C. elegans ORAI-1 protein; contains similarity to Pfam domain PF07856 Protein of unknown function (DUF1650) contains similarity to Interpro domain IPR012446 (Protein of unknown function DUF1650)
14	C15C8.1	C15C8.1	n/a	chrV 12,735,091	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003073 (Orphan nuclear receptor, NURR type)
15	M03F8.4	M03F8.4	n/a	chrV 5,932,159	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
16	K04H4.5	K04H4.5	n/a	chrIII 9,360,700	contains similarity to Yaba monkey tumor virus Yb-L1L protein.; TR:Q9QBC3
17	T04C10.3	T04C10.3	n/a	chrX 14,813,291	contains similarity to Rattus norvegicus Myosin heavy chain, nonmuscle type A (Cellular myosin heavy chain,stype A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).; SW:MYH9_RAT
18	pph-1	C05A2.1	n/a	chrV 10,703,698	C. elegans PPH-1 protein; contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
19	F59B10.6	F59B10.6	n/a	chrII 10,523,795	contains similarity to Prochlorococcus marinus Possible paralytic/GBP/PSP peptide precursor.; TR:Q7TUU1
20	F45E1.2	F45E1.2	n/a	chrX 8,003,850
21	C28F5.4	C28F5.4	n/a	chrII 7,521,547	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
22	T02E1.8	T02E1.8	n/a	chrI 8,236,518
23	twk-35	F31D4.7	n/a	chrV 20,859,750	C. elegans TWK-35 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
24	clk-1	ZC395.2	n/a	chrIII 5,278,572	clk-1 encodes the C. elegans ortholog of COQ7/CAT5, a highly conserved demethoxyubiquinone (DMQ) hydroxylase that is necessary for the biosynthesis of ubiquinone (coenzyme Q, Q9) from 5-demethoxyubiquinone (DMQ9); in C. elegans, CLK-1 activity is required for normal physiological rates of growth, development, behavior, and aging, as well as for normal brood sizes.
25	srh-174	F40D4.1	n/a	chrV 17,179,348	C. elegans SRH-174 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	Y48A6C.1	Y48A6C.1	n/a	chrIII 11,104,510	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
27	K06A9.3	K06A9.3	n/a	chrX 1,534,681	contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site)
28	scd-2	T10H9.2	n/a	chrV 6,636,446	C. elegans SCD-2 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR002919 (Protease inhibitor I8, cysteine-rich trypsin inhibitor-like), IPR000998 (MAM), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
29	fbxa-115	Y113G7B.3	n/a	chrV 20,186,739	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
30	irk-3	K04G11.5	n/a	chrX 14,356,108	C. elegans IRK-3 protein; contains similarity to Pfam domain PF01007 Inward rectifier potassium channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR014756 (Immunoglobulin E-set), IPR013518 (Potassium channel, inwardly rectifying, Kir, cytoplasmic), IPR001838 (Potassium channel, inwardly rectifying, Kir-like)
31	C39B10.4	C39B10.4	n/a	chrX 10,445,432	contains similarity to Brachydanio rerio Similar to synaptonemal complex protein 1 (Fragment).; TR:Q7ZVL0
32	C11G10.1	C11G10.1	n/a	chrX 15,157,907
33	F28E10.2	F28E10.2	n/a	chrIV 4,563,722	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF07974 (EGF-like domain) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular)
34	fip-4	F41E6.10	n/a	chrV 8,611,069	C. elegans FIP-4 protein
35	F07C6.3	F07C6.3	n/a	chrIV 12,789,701	contains similarity to Coxiella burnetii Hypothetical protein.; TR:Q83D43
36	ceeh-2	K07C5.5	n/a	chrV 10,357,064	ceeh-2 encodes a soluble epoxide hydrolase (sEH) orthologous to human ABHD7 and ABHD9; recombinant CEEH-2 is biochemically active in vitro on epoxyeicosatrienoic acids and leukotoxins (EpOMEs); conversely, CEEH-2 is inhibited by urea-based antagonists of mammalian sEH that elevate EpOME levels when fed to C. elegans; perhaps because of genetic redundancy with its paralog CEEH-1, CEEH-2 has no obvious function in mass RNAi assays.
37	ser-5	F16D3.7	n/a	chrI 8,385,819	F16D3.7 encodes a homolog of mammalian alpha-adrenergic receptors that is expressed in vulval and bodywall muscle cells, intestine, and head neurons; heterologously expressed F16D3.7 has no effect on adenylate cyclase signalling; F16D3.7 has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating.
38	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
39	wrt-8	C29F3.2	n/a	chrV 15,343,304	wrt-8 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a Wart domain, an short region of low-complexity sequence, and a Hint/Hog domain; WRT-8 is strongly expressed in hypodermal syncytia hyp6-hyp10 throughout life, and in in 12 subventral P cells and their descendants from 3-fold embryo to L2 larva stages; the Hint/Hog domain is predicted to cut WRT-8 into two halves and then covalently link cholesterol to the C-terminus of the Wart domain; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-8 has no obvious function in RNAi assays.
40	K11E4.1	K11E4.1	n/a	chrX 13,715,160	contains similarity to Pfam domain PF01764 (Lipase (class 3))
41	R04A9.3	R04A9.3	n/a	chrX 378,980
42	F35D11.1	F35D11.1	n/a	chrII 4,627,370
43	C14A6.3	C14A6.3	n/a	chrV 18,147,539	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
44	nhr-197	K06B4.7	n/a	chrV 15,688,881	C. elegans NHR-197 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
45	K08B4.5	K08B4.5	n/a	chrIV 6,087,860	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR011009 (Protein kinase-like), IPR001019 (Guanine nucleotide binding protein (G-protein), alpha subunit)
46	sma-3	R13F6.9	n/a	chrIII 6,862,404	sma-3 encodes a Smad protein; during development, SMA-3 functions as part of a DBL-1/SMA-6 TGF-beta-related signaling pathway that controls body size and male tail sensory ray and spicule formation; sma-3 is widely expressed at all developmental stages, beginning during embryogenesis, continuing through all larval stages, and seen very strongly in adult hermaphrodites and males; a SMA-3::GFP is detected in the pharynx, intestine, and hypodermis and localizes to the nucleus; sma-3 expression in the hypodermis is necessary and sufficient for normal body size; SMA-3 can physically interact with the LIN-31 forkhead transcription factor.
47	C38C3.6	C38C3.6	n/a	chrV 1,485,347	contains similarity to Interpro domain IPR000694 (Proline-rich region)
48	F23F1.3	F23F1.3	n/a	chrII 32,686
49	shw-3	R186.5	n/a	chrV 12,974,845	C. elegans SHW-3 protein; contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF07885 (Ion channel) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003973 (Potassium channel, voltage dependent, Kv2), IPR003970 (Potassium channel, voltage dependent, Kv8), IPR003971 (Potassium channel, voltage dependent, Kv9), IPR003968 (Potassium channel, voltage dependent, Kv), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR003969 (Potassium channel, voltage dependent, Kv6), IPR003091 (Voltage-dependent potassium channel), IPR013099 (Ion transport 2), IPR003974 (Potassium channel, voltage dependent, Kv3)
50	F25H2.2	F25H2.2	n/a	chrI 10,544,713	contains similarity to Pfam domains PF00595 (PDZ domain (Also known as DHR or GLGF)) , PF00787 (PX domain) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR001683 (Phox-like), IPR001478 (PDZ/DHR/GLGF)