UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C05D11.13	C05D11.13	6e-126	chrIII 6,443,485	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C11D2.1	C11D2.1	n/a	chrIV 6,191,401
4	Y57G11C.20	Y57G11C.20	0.0006	chrIV 14,844,297	contains similarity to Interpro domain IPR000003 ()
5	Y20C6A.1	Y20C6A.1	n/a	chrV 17,374,108	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
6	nhr-18	F44C8.3	n/a	chrV 2,228,092	The nhr-18 gene encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain; the human homolog of nhr-18, CYP21, when mutated leads to congenital adrenal hyperplasia (OMIM:201910).
7	srw-33	T26H5.5	n/a	chrV 15,450,551	C. elegans SRW-33 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000276 (GPCR, rhodopsin-like)
8	F26D11.2	F26D11.2	n/a	chrV 7,960,124
9	C31B8.4	C31B8.4	n/a	chrV 2,897,526	contains similarity to Homo sapiens cDNA FLJ77065, highly similar to Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA; ENSEMBL:ENSP00000349305
10	srz-100	T25E12.11	n/a	chrV 16,732,494	C. elegans SRZ-100 protein ;
11	R06B9.1	R06B9.1	n/a	chrII 13,764,398	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
12	pax-3	F27E5.2	n/a	chrII 10,149,568	pax-3 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; PAX-3 is required for locomotion and vulval development; pax-3(RNAi) animals have consistent Pvl and Unc phenotypes (as well as less consistent Bmd, Rup, and Stp phenotypes).
13	B0554.1	B0554.1	n/a	chrV 438,570
14	spp-6	T08A9.10	n/a	chrX 7,317,449	spp-6 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-6 is predicted to function as a lipid-binding protein that may possess pore-forming, cytotoxic activity; as loss of SPP-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of SPP-6 in C. elegans development and/or behavior is not yet known.
15	C03G6.6	C03G6.6	n/a	chrV 7,358,148	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
16	zig-2	F42F12.2	n/a	chrX 12,340,922	zig-2 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-2::gfp reporter fusion is expressed in the PVT interneuron and weakly in 4-6 additional head neurons.
17	ocr-3	T10B10.7	n/a	chrX 15,171,101	ocr-3 encodes a predicted TRPV channel (transient receptor potential cation channel, subfamily V) containing six membrane-spanning regions, cytoplasmic ankyrin repeats, and a long, unconserved cytoplasmic tail that is related to the mammalian TRPV1 cation channel (OMIM:602076) activated by capsaicin and other noxious stimuli; although the precise role of OCR-3 in C. elegans development and/or behavior is not yet known, OCR-3 expression is detected solely in the rectal gland cells and occasionally the glial socket cells of the head, suggesting that OCR-3 may function in sensory signal transduction in these cell types.
18	try-2	C07G1.1	n/a	chrIV 8,213,133	try-2 encodes a homolog of human TRYP1 and ELA2; mutation of human TRYP1 or ELA2 leads, respectively, to hereditary pancreatitis (OMIM:276000) or cyclic haematopoiesis (OMIM:162800).
19	mef-2	W10D5.1	n/a	chrI 9,097,999	mef-2 encodes a transcription factor that is the sole C. elegans member of the MEF2 subgroup of MADS box transcription factors; loss of mef-2 activity does not result in a strong visible phenotype, although mef-2 mutant adults are slightly dumpy (Dpy); in vitro, MEF-2 is able to bind a consensus MEF2 DNA binding site and interact with the class II histone deacetylase encoded by C10E2.3 (hda-4/hda-7); mef-2 mRNA is detected at all stages of development and expression of mef-2 reporter gene fusions begins in neurons during late embryogenesis and continues in all tissues throughout postembryonic development; mef-2 mutations do not appear to interact with mutations in other myogenic factors such as hlh-1, hlh-8, pha-1, and unc-120.
20	T28F4.4	T28F4.4	n/a	chrI 7,488,371	contains similarity to Brugia malayi Putative uncharacterized protein BMBAC01P19.05a.; TR:Q8IHI4
21	C07D10.1	C07D10.1	n/a	chrII 7,399,714	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
22	F35E8.13	F35E8.13	n/a	chrV 15,925,673	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
23	col-85	T21B4.2	n/a	chrII 12,494,362	C. elegans COL-85 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat), IPR013286 (Annexin, type VII)
24	C15B12.2	C15B12.2	n/a	chrX 6,464,379
25	F36G9.7	F36G9.7	n/a	chrV 15,968,760	contains similarity to Methanosarcina mazei Hypothetical protein MM0083.; TR:Q8Q0Q3
26	acl-1	F59F4.4	n/a	chrX 15,850,758	acl-1 encodes a 1-acyl-sn-glycerol-3-phosphate acyltransferase; ACL-1 is predicted to be a membrane protein that plays a role in phospholipid biosynthesis, but as loss of acl-1 activity via large-scale RNAi experiments results in no obvious defects, the precise role of ACL-1 in C. elegans development and/or behavior is not yet known.
27	srw-120	K12D9.5	n/a	chrV 2,995,551	C. elegans SRW-120 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
28	clec-249	Y51A2A.7	n/a	chrV 18,304,784	C. elegans CLEC-249 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
29	srbc-20	C45H4.11	n/a	chrV 2,147,858	C. elegans SRBC-20 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
30	fbxb-48	F45C12.13	n/a	chrII 1,718,632	C. elegans FBXB-48 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
31	col-114	D2024.8	n/a	chrIV 7,246,056	C. elegans COL-114 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
32	tag-199	F45E4.4	n/a	chrIV 7,612,783	C. elegans TAG-199 protein ; contains similarity to Trypanosoma brucei Putative uncharacterized protein.; TR:Q4GZ45
33	clec-59	ZK666.5	n/a	chrII 10,478,656	C. elegans CLEC-59 protein; contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
34	C36C5.12	C36C5.12	n/a	chrV 3,158,933	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
35	srd-4	ZK863.5	n/a	chrV 12,185,574	C. elegans SRD-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
36	C54F6.4	C54F6.4	n/a	chrV 7,530,843	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domain IPR004316 (MtN3 and saliva related transmembrane protein)
37	srx-56	C03G6.2	n/a	chrV 7,374,979	C. elegans SRX-56 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
38	old-2	ZK938.5	n/a	chrII 9,848,462	old-2 encodes a transmembrane protein tyrosine kinase (also known as 'kin-28') that affects mean and maximum life span with multiple paralogs in C. elegans; the expression of old-2 was experimentally verified by RT-PCR.
39	ttr-37	F21E9.3	n/a	chrX 1,336,135	C. elegans TTR-37 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
40	F49H6.5	F49H6.5	n/a	chrV 17,024,380	The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
41	C32D5.1	C32D5.1	n/a	chrII 6,344,783
42	C43F9.4	C43F9.4	n/a	chrIV 10,588,322
43	DH11.2	DH11.2	n/a	chrII 8,013,966	contains similarity to Pfam domain PF00646 (F-box domain)
44	C06A5.6	C06A5.6	n/a	chrI 5,984,551
45	C32F10.4	C32F10.4	n/a	chrI 5,809,249
46	F26G1.3	F26G1.3	n/a	chrII 4,759,013	F26G1.3 encodes a protein containing a transthyretin-like domain; the product of F26G1.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
47	C42C1.2	C42C1.2	n/a	chrIV 12,266,886	contains similarity to Pfam domain PF00481 Protein phosphatase 2C contains similarity to Interpro domains IPR001932 (Protein phosphatase 2C-related), IPR000222 (), IPR014045 (Protein phosphatase 2C, N-terminal), IPR015655 (Protein phosphatase 2C)
48	ZC196.2	ZC196.2	n/a	chrV 8,740,693	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
49	glt-5	Y53C12A.2	n/a	chrII 9,707,756	glt-5 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
50	ptr-16	T21H3.2	n/a	chrV 1,172,902	ptr-16 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-16 is partially required for normal molting from L2 to L3 larval stages; however, PTR-16 and PTR-1 together are strongly required for both molting and viability, with double ptr-1/-16 RNAi animals showing pronounced molting defects and lethality; PTR-16 is also required for normal growth to full size and locomotion.