UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C05C12.4	C05C12.4	2e-153	chrIV 11,247,231	contains similarity to Interpro domains IPR002049 (EGF-like, laminin), IPR013032 (EGF-like region, conserved site)
2	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
3	hmit-1.2	Y51A2D.5	n/a	chrV 18,526,923	hmit-1.2 encodes one of three C. elegans proton (H+)-dependent myo-inositol transporters; loss of hmit-1.2 activity via large-scale RNAi result in no obvious abnormalities but by homology, HMIT-1.2 is predicted to function as a plasma membrane protein required for the regulated uptake of myo-inositol and thus potentially for regulation of cell signaling and intracellular osmolarity.
4	F25E5.5	F25E5.5	n/a	chrV 7,448,059	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
5	opt-3	F56F4.5	n/a	chrI 6,135,613	C. elegans OPT-3 protein; contains similarity to Pfam domain PF00854 POT family contains similarity to Interpro domains IPR000109 (TGF-beta receptor, type I/II extracellular region), IPR000817 (Prion protein), IPR004768 (Oligopeptide transporter, peptide:H+ symporter), IPR016196 (MFS general substrate transporter)
6	Y49E10.16	Y49E10.16	n/a	chrIII 12,432,047	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)
7	inft-2	F15B9.4	n/a	chrV 13,004,645	C. elegans INFT-2 protein; contains similarity to Pfam domain PF02181 Formin Homology 2 Domain contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region), IPR003104 (Actin-binding FH2 and DRF autoregulatory), IPR000976 (Wilm's tumour protein)
8	F38A1.9	F38A1.9	n/a	chrIV 1,244,866
9	srr-9	T05B11.2	n/a	chrV 7,738,784	C. elegans SRR-9 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
10	F58H7.8	F58H7.8	n/a	chrIV 908,458
11	lec-4	C44F1.3	n/a	chrIII 3,772,356	lec-4 encodes a predicted galectin that exhibits sugar binding properties in vitro.
12	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
13	F42G2.4	F42G2.4	n/a	chrII 2,411,193	n/a
14	F59A7.2	F59A7.2	n/a	chrV 2,016,188
15	prx-2	ZK809.7	n/a	chrIV 11,645,165	prx-2 is orthologous to the human gene PEROXISOMAL MEMBRANE PROTEIN 3 (PXMP3; OMIM:170993), which when mutated leads to Zellweger syndrome 3 or infantile Refsum disease.
16	ttr-46	T07C12.7	n/a	chrV 9,951,666	C. elegans TTR-46 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
17	pah-1	K08F8.4	n/a	chrII 8,763,866	pah-1 encodes a biochemically active phenylalanine-4-hydroxylase orthologous to human PAH (OMIM:261600, mutated in phenylketonuria); recombinant PAH-1 has hydroxylase activity on phenylalanine and tryptophan substrates in vitro; pah-1 is expressed in seam cells, tail hypodermal cells, and ventral hypodermis, with stronger posterior than anterior expression; PAH-1 might help provide tyrosine for cross-linking in the cuticle, and is partially required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
18	F40A3.2	F40A3.2	n/a	chrV 7,880,134	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site)
19	wrt-8	C29F3.2	n/a	chrV 15,343,304	wrt-8 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a Wart domain, an short region of low-complexity sequence, and a Hint/Hog domain; WRT-8 is strongly expressed in hypodermal syncytia hyp6-hyp10 throughout life, and in in 12 subventral P cells and their descendants from 3-fold embryo to L2 larva stages; the Hint/Hog domain is predicted to cut WRT-8 into two halves and then covalently link cholesterol to the C-terminus of the Wart domain; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-8 has no obvious function in RNAi assays.
20	twk-35	F31D4.7	n/a	chrV 20,859,750	C. elegans TWK-35 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
21	F15E11.4	F15E11.4	n/a	chrV 2,340,462	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
22	C04E12.6	C04E12.6	n/a	chrV 3,355,089	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
23	K09C4.4	K09C4.4	n/a	chrX 3,290,202	contains similarity to Pfam domain PF00083 Sugar (and other) transporter contains similarity to Interpro domains IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
24	F56G4.1	F56G4.1	n/a	chrI 11,343,556	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
25	F47D12.3	F47D12.3	n/a	chrIII 6,298,853	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
26	srx-54	Y102A5C.22	n/a	chrV 16,975,937	C. elegans SRX-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
27	T18D3.8	T18D3.8	n/a	chrX 12,437,812
28	T12B3.3	T12B3.3	n/a	chrIV 7,375,883	contains similarity to Pfam domain PF03009 Glycerophosphoryl diester phosphodiesterase family contains similarity to Interpro domain IPR004129 (Glycerophosphoryl diester phosphodiesterase)
29	F56H11.6	F56H11.6	n/a	chrIV 9,528,961	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
30	K04F10.1	K04F10.1	n/a	chrI 6,365,571	The K04F10.1 gene encodes a homolog of SCA1, which when mutated leads to spinocerebellar ataxia 1 (OMIM:164400).
31	Y40B1B.5	Y40B1B.5	n/a	chrI 13,436,717	contains similarity to Homo sapiens Retinoblastoma binding protein 6 isoform 1; ENSEMBL:ENSP00000317872
32	C50F7.9	C50F7.9	n/a	chrIV 7,731,347
33	Y37D8A.6	Y37D8A.6	n/a	chrIII 12,857,304	contains similarity to Interpro domains IPR006629 (LPS-induced tumor necrosis factor alpha factor), IPR013032 (EGF-like region, conserved site)
34	upp-1	ZK783.2	n/a	chrIII 7,642,087	C. elegans UPP-1 protein; contains similarity to Pfam domain PF01048 Phosphorylase family contains similarity to Interpro domains IPR010059 (Uridine phosphorylase, eukaryotic), IPR000845 (Nucleoside phosphorylase)
35	H32K16.1	H32K16.1	n/a	chrI 9,151,388	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domain IPR013057 (Amino acid transporter, transmembrane)
36	F59F4.1	F59F4.1	n/a	chrX 15,836,220	contains similarity to Pfam domains PF01756 (Acyl-CoA oxidase) , PF02770 (Acyl-CoA dehydrogenase, middle domain) contains similarity to Interpro domains IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR012258 (Acyl-CoA oxidase), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR002655 (Acyl-CoA oxidase, C-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal)
37	dhs-30	T25G12.7	n/a	chrX 17,233,193	dhs-30 encodes a member of the short-chain dehydrogenases/reductases family (SDR) homologous to HSD, which when mutated leads to cortisol 11-beta ketoreductase deficiency (OMIM:218030).
38	K11G9.5	K11G9.5	n/a	chrV 6,687,134	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
39	his-37	C50F4.7	n/a	chrV 9,547,316	his-37 encodes an H4 histone.
40	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
41	F02C9.2	F02C9.2	n/a	chrV 3,135,542	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domains IPR005049 (Protein of unknown function DUF288), IPR002972 (Prostaglandin D synthase)
42	mxl-3	F46G10.6	n/a	chrX 13,350,149	C. elegans MXL-3 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding), IPR002418 (Transcription regulator Myc)
43	tyr-4	C34G6.2	n/a	chrI 5,900,210	C. elegans TYR-4 protein; contains similarity to Pfam domains PF00264 (Common central domain of tyrosinase) , PF01549 (ShK domain-like) (4)contains similarity to Interpro domains IPR000817 (Prion protein), IPR008922 (Di-copper centre-containing), IPR002227 (Tyrosinase), IPR003582 (Metridin-like ShK toxin)
44	cyp-33E1	C49C8.4	n/a	chrIV 8,646,858	C. elegans CYP-33E1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
45	F16B4.3	F16B4.3	n/a	chrV 1,597,417	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
46	F25F8.1	F25F8.1	n/a	chrI 4,890,200	contains similarity to Interpro domain IPR011042 (Six-bladed beta-propeller, TolB-like)
47	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
48	srp-5	C03G6.18	n/a	chrV 7,382,647	srp-5 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily; by homology, SRP-5 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases; however, as loss of srp-5 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-5 in C. elegans development and/or behavior is not yet known.
49	C09B7.2	C09B7.2	n/a	chrX 2,669,882
50	F25C8.4	F25C8.4	n/a	chrV 20,901,062	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)