UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	mog-4	C04H5.6	0	chrII 14,556,957	The mog-4 gene encodes a DEAH helicase orthologous to the Drosophila CG10689 and the S. cerevisiae PRP2 proteins.
2	ceh-20	F31E3.1	n/a	chrIII 6,980,772	ceh-20 encodes the C. elegans ortholog of the homeodomain co-factor Extradenticle (Exd/Pbx); together with ceh-40 and unc-62, ceh-20 activity is required for embryonic viability; ceh-20 is also required as a cofactor for LIN-39- and MAB-5- dependent postembryonic mesoderm patterning; in addition, ceh-20 is required for regulating post-embryonic migrations of the Q neuroblast descendants and for regulating vulval development; a CEH-20::GFP fusion protein is expressed in embryos and postembryonically in many cell types including the Q, P, and V cells and their descendants; CEH-20 localizes to the nucleus.
3	F22B3.5	F22B3.5	n/a	chrIV 11,416,056	contains similarity to Interpro domains IPR001304 (C-type lectin), IPR006583 (CW)
4	F25B4.2	F25B4.2	n/a	chrV 5,710,856	contains similarity to Pfam domain PF04710 Pellino contains similarity to Interpro domain IPR006800 (Pellino)
5	F29D11.2	F29D11.2	n/a	chrI 7,637,136	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
6	tag-50	M176.1	n/a	chrII 9,413,277	tag-50 encodes a predicted member of the arrestin family.
7	ceh-40	F17A2.5	n/a	chrX 12,319,393	ceh-40 encodes one of two C. elegans homeodomain proteins homologous to Extradenticle (Exd/Pbx); ceh-40 genetically interacts with ceh-20 and unc-62 during embryonic development: while loss of ceh-40 activity alone results in no significant embryonic lethality, loss of ceh-40 and ceh-20, or ceh-40, ceh-20, and unc-62, results in incompletely penetrant embryonic lethality.
8	F41G3.2	F41G3.2	n/a	chrII 6,759,863
9	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
10	C43H6.7	C43H6.7	n/a	chrX 2,400,426	contains similarity to Pfam domain PF01529 DHHC zinc finger domain contains similarity to Interpro domains IPR001594 (Zinc finger, DHHC-type), IPR016201 (Plexin-like fold)
11	F53G2.8	F53G2.8	n/a	chrII 2,483,639
12	W07E6.3	W07E6.3	n/a	chrII 496,617	contains similarity to Interpro domain IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase)
13	T22F7.1	T22F7.1	n/a	chrIII 544,286	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR006655 (Molybdopterin oxidoreductase, prokaryotic, conserved site), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
14	T03G6.3	T03G6.3	n/a	chrX 2,613,474	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017850 (Alkaline-phosphatase-like, core domain)
15	R74.6	R74.6	n/a	chrIII 4,203,243	contains similarity to Pfam domains PF03465 (eRF1 domain 3) , PF03464 (eRF1 domain 2) , PF03463 (eRF1 domain 1) contains similarity to Interpro domains IPR004405 (Probable translation factor pelota), IPR005140 (eRF1 domain 1), IPR005141 (eRF1 domain 2), IPR005142 (eRF1 domain 3)
16	C29G2.3	C29G2.3	n/a	chrV 2,581,907
17	C27F2.7	C27F2.7	n/a	chrIII 4,982,522	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
18	C40A11.3	C40A11.3	n/a	chrII 2,142,086	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
19	bath-39	F25H9.4	n/a	chrV 13,460,604	C. elegans BATH-39 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
20	srt-15	C50H11.10	n/a	chrV 3,060,908	C. elegans SRT-15 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
21	C17H11.2	C17H11.2	n/a	chrX 8,171,341
22	dnj-23	T24H10.3	n/a	chrII 9,107,885	This gene encodes a protein containing a DnaJ ('J') domain.
23	arx-3	Y79H2A.6	n/a	chrIII 12,055,279	arx-3 encodes the C. elegans ortholog of the p41Arc subunit of the actin-related protein (Arp)2/3 complex.
24	F52H2.4	F52H2.4	n/a	chrX 2,546,392	contains similarity to Pfam domain PF00474 Sodium:solute symporter family contains similarity to Interpro domains IPR010979 (Ribosomal protein S13-like, H2TH), IPR001734 (Na+/solute symporter)
25	hsp-6	C37H5.8	n/a	chrV 4,825,414	hsp-6 encodes a mitochondrial-specific chaperone that is a member of the DnaK/Hsp70 superfamily of molecular chaperones; hsp-6 is believed to be involved in the mitochondrial unfolded protein response, as hsp-6 expression, normally broadly detected from the L1 larval through adult stages of development, is greatly increased in response to treatments that disrupt mitochondrial protein handling; loss of hsp-6 activity via RNAi results in severe growth defects with arrest at embryonic and early larval stages of development.
26	tsp-3	Y39E4B.4	n/a	chrIII 13,213,403	C. elegans TSP-3 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domain IPR000301 (CD9/CD37/CD63 antigen)
27	T23E1.2	T23E1.2	n/a	chrIV 3,144,252
28	F13H6.5	F13H6.5	n/a	chrV 6,373,505	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
29	F33D11.5	F33D11.5	n/a	chrI 5,836,021	contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
30	T07F12.1	T07F12.1	n/a	chrX 4,895,096	T07F12.1 encodes a member of the histidine phosphatase superfamily orthologous to Bombyx mori ecdysteroid phosphate phosphatase (EPP), human STS1 (OMIM:609201) and human UBASH3A (OMIM:605736); in cell culture, recombinant T07F12.1 is a cytosolic enzyme with steroid phosphatase activity on ecdysone 22-phosphate (E22P), 3-epiecdysone 22-phosphate, 3-epiecdysone 2-phosphate substrates, and prednisolone 21-phosphate substrates, with E22P being preferred; T07F12.1 has no activity against 3-epiecdysone 3(alpha)-phosphate or 1-dehydrotestosterone sodium sulphate; unlike its Bombyx or mammalian orthologs, T07F12.1 lacks non-catalytic SH3 and UBA domains; T07F12.1 is paralogous to C. elegans C52E4.7, F09C12.8, F53B6.7, and F55A11.11.
31	T21B4.3	T21B4.3	n/a	chrII 12,495,897	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
32	aco-1	ZK455.1	n/a	chrX 11,341,447	aco-1 encodes an aconitase that is homologous to mammalian iron regulatory protein-1 (IRP1); aco-1 activity is required for normal brood sizes and, under iron stress conditions, for normal lifespan and L4-to-adult growth rates; ACO-1 physically interacts with GEX-3; like IRP1, ACO-1 has aconitase activity and is post-translationally regulated by iron, but, unlike IRP1, it lacks RNA-binding activity; ACO-1 is predicted to be mitochondrial, and its mRNA levels appear to decrease in response to iron treatment.
33	T07D1.5	T07D1.5	n/a	chrX 2,419,146
34	T07F12.2	T07F12.2	n/a	chrX 4,891,246	contains similarity to Pfam domain PF02225 PA domain contains similarity to Interpro domain IPR003137 (Protease-associated PA)
35	clec-93	ZK39.4	n/a	chrI 11,143,094	C. elegans CLEC-93 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
36	fbxb-100	Y63D3A.2	n/a	chrI 14,093,529	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
37	ZK757.2	ZK757.2	n/a	chrIII 9,875,718	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
38	F09E10.5	F09E10.5	n/a	chrX 1,492,033
39	srt-63	T28A11.15	n/a	chrV 3,255,375	C. elegans SRT-63 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
40	F02C12.3	F02C12.3	n/a	chrX 13,397,291
41	C05E7.4	C05E7.4	n/a	chrX 12,966,891	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
42	sprr-2	F42D1.3	n/a	chrX 14,802,137	C. elegans SPRR-2 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
43	W03C9.5	W03C9.5	n/a	chrII 11,967,205	contains similarity to Arabidopsis thaliana F25C20.11 protein.; TR:Q9SAA3
44	F31D4.2	F31D4.2	n/a	chrV 20,838,947	contains similarity to Pfam domain PF01937 Protein of unknown function DUF89 contains similarity to Interpro domains IPR000408 (Regulator of chromosome condensation, RCC1), IPR002791 (Protein of unknown function DUF89)
45	F53A2.1	F53A2.1	n/a	chrIII 13,321,932	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR009497 (Protein of unknown function DUF1114), IPR009010 (Aspartate decarboxylase-like fold)
46	lgc-40	T24D8.1	n/a	chrX 2,362,451	C. elegans LGC-40 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
47	B0412.3	B0412.3	n/a	chrIII 802,243	contains similarity to Pfam domain PF07919 Protein of unknown function (DUF1683) contains similarity to Interpro domain IPR012880 (Protein of unknown function DUF1683, C-terminal)
48	vha-1	R10E11.8	n/a	chrIII 9,781,407	vha-1 encodes an ortholog of subunit c of the membrane-bound (V0) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-1 is a predicted V-ATPase transmembrane rotor component; VHA-1 and VHA-2/3 comprise a closely related family of subunit c co-orthologs, predicted to carry protons from the cytosol to a-subunits (VHA-5, VHA-6, VHA-7, or UNC-32) for transmembrane export; VHA-1, like VHA-12 and VHA-17, antagonizes EFF-1-mediated cell fusion in hypodermal cells; VHA-1 is required for ovulation and embryogenesis, since vha-1(RNAi) animals are sterile with polyploid, unmatured oocytes and dead progeny; VHA-1 is required for alae formation, like the V0 subunits VHA-4 and VHA-5, but not like the V1 subunits VHA-8 or VHA-13; vha-1 shares an operon with vha-2 and R10E11.6; both vha-1 and vha-2 are expressed in the excretory cell, the rectum, and a pair of cells near the anus.
49	C41H7.4	C41H7.4	n/a	chrII 3,004,748	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
50	gck-4	C04A11.3	n/a	chrX 13,679,590	C. elegans GCK-4 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)