UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cht-1	C04F6.3	0	chrX 3,398,895	cht-1 encodes a chitinase orthologous to human chitinase-1 (OMIM:600031, mutations are associated with chitotriosidase deficiency); CHT-1 is predicted to function as an extracellular O-glycosyl hydrolase that hydrolyzes the glycosidic bond between two or more carbohydrates; in C. elegans, CHT-1 may play a role in embryogenesis, and may also be required for cuticle degradation during molting and degradation of chitin-containing pathogens as part of a host defense mechanism.
2	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
3	K10B3.5	K10B3.5	n/a	chrX 3,104,756	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
4	Y69H2.7	Y69H2.7	n/a	chrV 18,693,003	contains similarity to Saccharomyces cerevisiae appears to control expression of spliceosome components PRP4 and PRP3; SGD:YDR464W
5	uvt-7	ZK563.1	n/a	chrX 3,395,198	uvt-7 encodes a transmembrane permease of the major facilitator superfamily (MFS) that by homology, is predicted to transport metabolites across cellular membranes in response to chemiosmotic gradients; uvt-7 was first identified in molecular analyses of gene products linked to the vitellogenin (vit) loci on the X chromosome; as loss of uvt-7 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of uvt-7 in C. elegans development and/or behavior is not yet known; uvt-7 mRNA is detected in embryos and adults, suggesting that uvt-7 may be a maternally expressed gene.
6	F34H10.3	F34H10.3	n/a	chrX 9,634,393	contains similarity to Anabaena sp Hypothetical protein Asr1307.; TR:Q8YXA8
7	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	sra-18	F28C12.2	n/a	chrI 12,692,935	C. elegans SRA-18 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
9	F29G6.2	F29G6.2	n/a	chrX 11,510,328	contains similarity to Homo sapiens cDNA FLJ43363 fis, clone NT2RP7017474; ENSEMBL:ENSP00000374260
10	K04G2.4	K04G2.4	n/a	chrI 8,036,493	contains similarity to Tetrahymena thermophila Histone H1.; SW:H1_TETTH
11	fbxb-11	F45C12.5	n/a	chrII 1,725,771	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
12	C11H1.3	C11H1.3	n/a	chrX 14,309,889	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
13	srx-17	F55B12.8	n/a	chrV 13,841,443	C. elegans SRX-17 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
14	E01G4.5	E01G4.5	n/a	chrII 13,473,085	contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000215 (Protease inhibitor I4, serpin)
15	C02E7.10	C02E7.10	n/a	chrV 4,931,908
16	R03C1.1	R03C1.1	n/a	chrII 14,908,902	contains similarity to Homo sapiens Mucin-5AC precursor (Fragment); ENSEMBL:ENSP00000351148
17	col-105	F58F6.2	n/a	chrIV 1,358,519	C. elegans COL-105 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
18	F47D12.5	F47D12.5	n/a	chrIII 6,283,998	contains similarity to Homo sapiens Isoform 1 of Protein zyg-11 homolog B; ENSEMBL:ENSP00000294353
19	F10C2.3	F10C2.3	n/a	chrV 12,022,395	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
20	fbxb-20	ZC204.9	n/a	chrII 1,649,687	fbxb-20 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-20 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
21	fbxa-154	B0391.6	n/a	chrV 15,603,958	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
22	T15B7.15	T15B7.15	n/a	chrV 6,837,660	contains similarity to Interpro domain IPR000533 (Tropomyosin)
23	srh-28	ZC404.5	n/a	chrV 6,774,975	C. elegans SRH-28 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	fbxb-49	K05F6.1	n/a	chrII 1,570,989	C. elegans FBXB-49 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
25	R03D7.8	R03D7.8	n/a	chrII 10,955,158	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
26	W05F2.7	W05F2.7	n/a	chrI 3,357,913	contains similarity to Interpro domain IPR000694 (Proline-rich region)
27	B0496.4	B0496.4	n/a	chrIV 7,428,290	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
28	C14H10.1	C14H10.1	n/a	chrX 10,235,306	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
29	T07F8.2	T07F8.2	n/a	chrII 7,145,876	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
30	R05D11.5	R05D11.5	n/a	chrI 8,592,502	contains similarity to Pfam domain PF05620 Protein of unknown function (DUF788) contains similarity to Interpro domain IPR008506 (Protein of unknown function DUF788)
31	C14A11.2	C14A11.2	n/a	chrX 2,803,965
32	cin-4	ZK1127.7	n/a	chrII 7,039,709	C. elegans CIN-4 protein
33	nmr-2	T01C3.10	n/a	chrV 15,009,000	C. elegans NMR-2 protein ;
34	cul-1	D2045.6	n/a	chrIII 10,473,304	cul-1 encodes a cullin, orthologous to Cdc53/Cul1 in S. cerevisiae and CUL-1 in humans (OMIM:603134), that is required both maternally and zygotically for developmentally programmed transitions from the G1 phase of the cell cycle to the GO phase or the apoptotic pathway, and that is probably also required for normally slow G1-to-S phase progression; CUL-1 physically interacts with eight Skp1-related proteins (SKR-1, -2, -3, -4, -7, -8, -9, and -10).
35	C07E3.6	C07E3.6	n/a	chrII 10,368,675	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
36	F39E9.7	F39E9.7	n/a	chrII 3,306,570	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
37	F56C3.5	F56C3.5	n/a	chrX 1,363,402
38	fbxb-2	T26H2.3	n/a	chrV 19,236,658	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
39	tag-246	ZK1128.5	n/a	chrIII 10,121,745	ZK1128.5/tag-246 encodes an ortholog of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D (SMARCD) proteins; ZK1128.5/TAG-246 is required for full levels of LIN-3/EGF signalling during vulval development, though this effect is only visible in genetically sensitized backgrounds.
40	ZK1067.2	ZK1067.2	n/a	chrII 9,218,954	contains similarity to Pfam domain PF01422 NF-X1 type zinc finger contains similarity to Interpro domains IPR000967 (Zinc finger, NF-X1-type), IPR000694 (Proline-rich region), IPR001555 (Phosphoribosylglycinamide formyltransferase, active site), IPR000169 (Peptidase, cysteine peptidase active site)
41	sdz-30	T04D3.2	n/a	chrI 13,307,433	C. elegans SDZ-30 protein; contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
42	F58D2.1	F58D2.1	n/a	chrIV 13,184,996	contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR016024 (Armadillo-type fold)
43	srw-95	H06H21.2	n/a	chrIV 4,813,069	C. elegans SRW-95 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
44	C06E2.2	C06E2.2	n/a	chrX 8,879,967
45	cyp-14A4	R04D3.1	n/a	chrX 13,283,058	C. elegans CYP-14A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
46	fzy-1	ZK177.6	n/a	chrII 5,502,742	fzy-1 encodes an ortholog of S. cerevisiae Cdc20p that is required for the metaphase-to-anaphase transition, the deposition of extra meiotic chromosomes to polar bodies, and postembryonic vulval development; on the basis of orthology, FZY-1 is predicted to regulate anaphase-promoting complex (APC); FZY-1 protein is found in early embryonic cells at prometaphase and metaphase of mitosis and meiosis I, being localized to condensed chromosomes in prometaphase, and chromosomes on the metaphase plate during metaphase; FZY-1 binds IFY-1 and MDF-2 in yeast two-hybrid experiments; the missense fzy-1(h1983) mutation suppresses the lethal phenotype of mdf-1; fzy-1(RNAi) animals have vulval defects reflecting those seen in homozygotes for mat-3(ku233), whereas mat-3(ku233) is partly suppressed by RNAi of the fzy-1 paralog fzr-1.
47	K02D10.5	K02D10.5	n/a	chrIII 8,777,270	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domain IPR000727 (Target SNARE coiled-coil region)
48	R186.1	R186.1	n/a	chrV 12,962,447	contains similarity to Pfam domain PF05742 Protein of unknown function (DUF833) contains similarity to Interpro domain IPR008551 (Protein of unknown function DUF833)
49	F11C1.1	F11C1.1	n/a	chrX 12,988,210	contains similarity to Pfam domain PF06747 CHCH domain contains similarity to Interpro domain IPR010625 (CHCH)
50	ZK632.7	ZK632.7	n/a	chrIII 9,821,105	contains similarity to Interpro domain IPR011009 (Protein kinase-like)