UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ugt-63	C04F5.7	0	chrV 5,109,468	C. elegans UGT-63 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
2	lbp-7	T22G5.2	n/a	chrV 13,879,814	lbp-7 encodes a predicted intracellular fatty acid binding protein (iFABP) that is most similar to the vertebrate muscle and heart FABPs; by homology, LBP-7 is predicted to function as an intracellular transporter for small hydrophobic molecules such as lipids and steroid hormones; as loss of lbp-7 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of LBP-7 in C. elegans development and/or behavior is not yet known.
3	clec-56	F08H9.7	n/a	chrV 14,475,609	C. elegans CLEC-56 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
4	nhx-2	B0495.4	n/a	chrII 7,692,262	nhx-2 encodes a sodium/proton exchanger expressed in the apical membranes of intestinal cells; NHX-2 is required for normally high growth rates, and for propagation or maintenance of the germline, NHX-2 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of extracellular sodium for an intracellular proton.
5	ncx-7	C07A9.11	n/a	chrIII 9,717,988	ncx-7 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6 and NCX-8/-10; NCX-7 may function intracellularly; NCX-7 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-7 has no obvious function in mass RNAi assays.
6	clec-57	F08H9.6	n/a	chrV 14,470,810	C. elegans CLEC-57 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
7	aqp-11	ZK525.2	n/a	chrIII 13,673,891	aqp-11 encodes a putative aquaporin with no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-9 and AQP-10; AQP-11 is orthologous to Drosophila CG12251 and human AQP11 (OMIM:609914), AQP12A (OMIM:609789), and AQP12B.
8	dct-18	F58G1.4	n/a	chrII 12,932,607	C. elegans DCT-18 protein; contains similarity to Interpro domain IPR000886 (Endoplasmic reticulum, targeting sequence)
9	K06A4.5	K06A4.5	n/a	chrV 9,506,309	contains similarity to Pfam domain PF06052 3-hydroxyanthranilic acid dioxygenase contains similarity to Interpro domains IPR011051 (Cupin, RmlC-type), IPR016700 (3-hydroxyanthranilate 3, 4-dioxygenase, metazoan), IPR010329 (3-hydroxyanthranilic acid dioxygenase)
10	F36H1.5	F36H1.5	n/a	chrIV 11,030,632	contains similarity to Agrobacterium tumefaciens Hypothetical protein Atu4002.; TR:Q8U8T6
11	Y47H9C.1	Y47H9C.1	n/a	chrI 11,832,085	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
12	sur-5	K03A1.5	n/a	chrX 7,303,412	sur-5 encodes a protein with high similarity to H. sapiens Acetoacetyl-coenzyme A synthetase; sur-5 negatively regulates let-60 during vulval induction, based on genetic analysis, and genetically synergises with lin-45 with respect to larval death, uncoordinated movement and egg-laying defects; sur-5 is strongly expressed in most cells of C. elegans, including the VPCs and is localized primarily to the nucleus.
13	R08E5.3	R08E5.3	n/a	chrV 3,773,366	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) , PF02390 (Putative methyltransferase) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11), IPR003358 (Putative methyltransferase)
14	F32A5.3	F32A5.3	n/a	chrII 7,234,327	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
15	C26B9.5	C26B9.5	n/a	chrX 5,330,863	contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domain IPR008758 (Peptidase S28)
16	ugt-8	H23N18.3	6e-22	chrV 4,904,931	C. elegans UGT-8 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
17	F28A10.6	F28A10.6	n/a	chrII 847,752	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02771 (Acyl-CoA dehydrogenase, N-terminal domain) contains similarity to Interpro domains IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR006089 (Acyl-CoA dehydrogenase, conserved site), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal), IPR006092 (Acyl-CoA dehydrogenase, N-terminal)
18	cyp-35A1	C03G6.14	n/a	chrV 7,360,867	C. elegans CYP-35A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR001756 (ATPase, P-type copper-transporter)
19	gst-36	R07B1.4	n/a	chrX 9,862,249	C. elegans GST-36 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR003083 (S-crystallin), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
20	F49F1.5	F49F1.5	n/a	chrIV 4,119,922	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
21	R07H5.8	R07H5.8	n/a	chrIV 11,210,138	contains similarity to Pfam domain PF00294 pfkB family carbohydrate kinase contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR002139 (Ribokinase), IPR001805 (Adenosine kinase), IPR002173 (Carbohydrate/puine kinase, PfkB, conserved site)
22	C18E9.5	C18E9.5	n/a	chrII 8,970,895	contains similarity to Turkey herpesvirus LORF11.; TR:Q9IBS2
23	C29F7.3	C29F7.3	n/a	chrX 13,419,306	contains similarity to Pfam domain PF00406 Adenylate kinase contains similarity to Interpro domains IPR000764 (Uridine kinase), IPR000850 (Adenylate kinase), IPR006266 (UMP-CMP kinase), IPR011769 (Adenylate/cytidine kinase, N-terminal)
24	amt-4	C05E11.5	n/a	chrX 4,567,404	amt-4 encodes a member of the ammonium transporter protein family.
25	T25D3.2	T25D3.2	n/a	chrII 155,462	contains similarity to Mus musculus 39S ribosomal protein L28, mitochondrial precursor (L28mt) (MRP-L28).; SW:Q9D1B9
26	ZC416.6	ZC416.6	n/a	chrIV 3,611,139	n/a
27	K08D8.6	K08D8.6	n/a	chrIV 12,888,793	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003492 (Batten's disease protein Cln3), IPR003366 (CUB-like region)
28	F58B4.5	F58B4.5	n/a	chrV 10,933,422	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
29	dnj-11	F38A5.13	n/a	chrIV 6,587,011	This gene encodes a protein containing a DnaJ ('J') domain.
30	K10C2.1	K10C2.1	n/a	chrX 6,425,780	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001563 (Peptidase S10, serine carboxypeptidase)
31	C15C8.3	C15C8.3	n/a	chrV 12,743,084	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001461 (Peptidase A1)
32	alh-9	F01F1.6	n/a	chrIII 5,858,031	C. elegans ALH-9 protein; contains similarity to Pfam domain PF00171 Aldehyde dehydrogenase family contains similarity to Interpro domains IPR016163 (Aldehyde dehydrogenase, C-terminal), IPR016162 (Aldehyde dehydrogenase, N-terminal), IPR016161 (Aldehyde/histidinol dehydrogenase), IPR015590 (Aldehyde dehydrogenase), IPR016160 (Aldehyde dehydrogenase, conserved site)
33	cyp-35A4	C49G7.8	n/a	chrV 4,032,492	C. elegans CYP-35A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
34	F59B8.2	F59B8.2	n/a	chrIV 9,439,991	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004790 (Isocitrate dehydrogenase NADP-dependent, eukaryotic), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
35	dap-3	C14A4.2	n/a	chrII 10,581,748	dap-3 is an ortholog of mammalian death-associated protein 3 (DAP3), a mitochondrial ribosomal protein that promotes apoptosis.
36	folt-2	F37B4.7	n/a	chrV 2,874,024	folt-2 encodes a putative folate transporter; FOLT-2 is orthologous to human SLC19A1 (OMIM:600424), SLC19A2 (OMIM:603941, mutated in thiamine-responsive megaloblastic anemia syndrome), and SLC19A3 (OMIM:606152, mutated in biotin-responsive basal ganglia disease); heterologously expressed FOLT-2 does not significantly transport folate; FOLT-2 has no obvious function in mass RNAi assays, perhaps because of genetic redundancy with its paralogs FOLT-1 and FOLT-3.
37	F35E12.5	F35E12.5	n/a	chrV 13,737,761	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
38	daf-36	C12D8.5	n/a	chrV 10,224,591	daf-36 encodes a protein homologous to the catalytic subunit of Rieske-like oxygenases; DAF-36 functions in a hormone biosynthetic pathway producing a ligand for the DAF-12 nuclear receptor that regulates the developmental decision between reproductive growth and dauer formation; a daf-36::gfp reporter fusion is expressed in the intestine, the head mesodermal cell, two unidentified head neurons (not XXXR/L) and, in dauers, the lateral seam cells; DAF-36 localizes to the cytoplasm in the intestine and to a cytosolic meshwork in dauer seam cells.
39	gsto-1	C29E4.7	n/a	chrIII 7,946,235	gsto-1 encodes an experimentally verified thiol oxidoreductase and dehydroascorbate reductase, required for normal stress resistance; formally, GSTO-1 is an omega-class glutathione transferase (GST; EC 2.5.1.18), but it has little activity in vitro on classic GST substrates; GSTO-1 is expressed in postembryonic intestine; gsto-1(RNAi) induces hypersensitivity to heat-, arsenite-, juglone-, paraquat-, or cumene hydroperoxide-induced stresses, whereas overexpression of GSTO-1 enhances resistance to them; gsto-1 transcription is upregulated by stress; ELT-2 may directly activate gsto-1 transcription in developing gut via a 300-nucleotide sequence upstream of gsto-1's ATG start site.
40	T02G5.4	T02G5.4	n/a	chrII 7,083,184	contains similarity to Pfam domains PF02803 (Thiolase, C-terminal domain) , PF00108 (Thiolase, N-terminal domain) contains similarity to Interpro domains IPR016038 (Thiolase-like, subgroup), IPR002155 (Thiolase), IPR016039 (Thiolase-like)
41	F13H6.3	F13H6.3	n/a	chrV 6,364,531	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
42	F11C1.3	F11C1.3	n/a	chrX 12,983,754	contains similarity to Pfam domain PF01130 CD36 family contains similarity to Interpro domain IPR002159 (CD36 antigen)
43	T08B1.1	T08B1.1	n/a	chrV 1,984,861	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR000817 (Prion protein), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
44	C44B7.7	C44B7.7	n/a	chrII 6,879,653	contains similarity to Homo sapiens Uncharacterized protein C7orf24; ENSEMBL:ENSP00000275428
45	F01F1.9	F01F1.9	n/a	chrIII 5,862,653	contains similarity to Pfam domain PF02127 Aminopeptidase I zinc metalloprotease (M18) contains similarity to Interpro domain IPR001948 (Peptidase M18, aminopeptidase I)
46	K11D12.5	K11D12.5	n/a	chrV 5,030,085	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domains IPR001411 (Tetracycline resistance protein, TetB), IPR004316 (MtN3 and saliva related transmembrane protein)
47	eft-1	ZK328.2	n/a	chrIII 6,011,147	eft-1 encodes an elongation factor 2 (EF-2)-like protein; by homology, EFT-1 is predicted to function as a GTPase required for the elongation step of protein synthesis; loss of eft-1 activity via large-scale RNAi indicates that eft-1 is an essential gene required for embryonic development, reproduction, and the overall health of the animal; eft-1 mRNA is detectable at all stages of C. elegans development.
48	cyp-35C1	C06B3.3	n/a	chrV 13,897,551	C. elegans CYP-35C1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
49	W09D10.3	W09D10.3	n/a	chrIII 10,708,021	contains similarity to Pfam domain PF00542 Ribosomal protein L7/L12 C-terminal domain contains similarity to Interpro domains IPR013823 (Ribosomal protein L7/L12, C-terminal), IPR014719 (Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like), IPR008932 (Ribosomal protein L7/L12, oligomerisation)
50	D1025.2	D1025.2	n/a	chrX 14,514,552	contains similarity to Pfam domain PF01597 Glycine cleavage H-protein contains similarity to Interpro domains IPR017453 (Glycine cleavage H-protein, subgroup), IPR011053 (Single hybrid motif), IPR002930 (Glycine cleavage H-protein)