UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srab-1	C04F5.4	0	chrV 5,101,092	C. elegans SRAB-1 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	abf-3	F54B8.5	n/a	chrV 15,817,602	abf-3 encodes a homolog of the antibacterial factor ASABF from Ascaris suum; ABF-3 may play a role in innate immunity, though at present the only evidence for its having an antimicrobial humoral function is its sequence similarity.
4	srh-23	C02E7.5	n/a	chrV 4,921,905	C. elegans SRH-23 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	T20D4.17	T20D4.17	n/a	chrV 3,395,750	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
6	daf-11	B0240.3	n/a	chrV 11,721,848	The daf-11 gene encodes a guanylate cyclase that affects dauer formation, chemotaxis, and axon formation; it is genetically upstream of daf-12 with respect to dauer larvae formation and is expressed in a subset of amphid neurons.
7	F09F3.5	F09F3.5	n/a	chrV 13,851,828	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal)
8	B0554.5	B0554.5	n/a	chrV 425,501	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR016196 (MFS general substrate transporter)
9	tni-4	W03F8.1	n/a	chrIV 5,205,854	tni-4 encodes one of the four elegans troponin I proteins; tni-4 is required for the normal development of the pharynx during embryonic development; TNI-4 interacts only with the pharyngeal troponin C; tni-4 is expressed exclusively in the pharyngeal muscles.
10	D1022.5	D1022.5	n/a	chrII 7,458,058
11	exc-9	F20D12.5	n/a	chrIV 7,940,302	exc-9 encodes a LIM domain-containing protein; exc-9 activity is required for proper development and morphogenesis of the excretory cell canal.
12	srx-34	T01C4.4	n/a	chrV 7,119,646	C. elegans SRX-34 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
13	R09D1.5	R09D1.5	n/a	chrII 9,448,892	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
14	glb-8	C26C6.7	n/a	chrI 7,510,602	glb-8 encodes a globin with no obvious function in mass RNAi assays; glb-8 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-8 expression is downregulated in a daf-2(e1370) mutant background under normoxic conditions; glb-8 expression is lower in L3 larvae than in young adults or dauers.
15	srb-15	C48B6.5	0.0005	chrI 6,899,186	C. elegans SRB-15 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
16	C39B10.5	C39B10.5	n/a	chrX 10,447,468	contains similarity to Saccharomyces cerevisiae bZIP protein; transcription factor; SGD:YIR018W
17	sra-6	AH6.10	n/a	chrII 9,549,075	sra-6 encodes a seven-transmembrane chemosensory receptor; an sra-6::GFP fusion reporter is expressed in the ASH (strongly) and ASI (weakly) amphid sensory neurons, the PVQ interneurons, and in the SPD and SPV male spicule neurons; sra-6 expression in the ASH neurons is positively regulated by KIN-29, a serine/threonine kinase, acting through the HDA-4 class II histone deacetylase and the MEF-2 MADS domain transcription factor; in addition, maintenance of sra-6::gfp expression in the ASH and ASI requires activity of the DAF-7/TGF-beta signaling pathway.
18	T21E12.3	T21E12.3	n/a	chrI 4,403,989	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
19	srh-137	Y70C5C.4	n/a	chrV 16,716,048	C. elegans SRH-137 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	str-46	C31B8.6	n/a	chrV 2,899,200	C. elegans STR-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	T16D1.1	T16D1.1	n/a	chrII 5,241,424
22	col-78	W07A12.5	n/a	chrII 9,153,340	C. elegans COL-78 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
23	F08G12.3	F08G12.3	n/a	chrX 11,301,106	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I5Q0
24	srh-129	F14F9.7	n/a	chrV 5,143,034	C. elegans SRH-129 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1), IPR001036 (Acriflavin resistance protein), IPR010916 (TonB box, conserved site)
25	Y102A5C.27	Y102A5C.27	n/a	chrV 16,988,446	contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
26	ZK892.6	ZK892.6	n/a	chrII 9,979,541	contains similarity to Vibrio parahaemolyticus Hypothetical protein.; TR:Q87PB2
27	clec-231	C29F3.4	n/a	chrV 15,350,031	C. elegans CLEC-231 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	F55G7.3	F55G7.3	n/a	chrX 11,941,116	contains similarity to Saccharomyces cerevisiae appears to control expression of spliceosome components PRP4 and PRP3; SGD:YDR464W
29	F56H6.9	F56H6.9	n/a	chrI 12,305,199	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
30	srh-219	C06B8.6	n/a	chrV 15,496,906	C. elegans SRH-219 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	dsl-4	F16B12.2	n/a	chrX 14,091,441	dsl-4 encodes a putative secreted protein with a single DSL domain and three EGF domains in series, somewhat like Delta/LAG-2; unlike the nematode-specific family of Delta/LAG-2-like proteins (including DSL-1, -2, -3, -5, -6, and -7), DSL-4 is evolutionarily divergent, with perhaps a distant affinity to APX-1, ARG-1, and LAG-2.
32	srv-7	T22B7.5	n/a	chrX 5,643,888	C. elegans SRV-7 protein; contains similarity to Interpro domain IPR000832 (GPCR, family 2, secretin-like)
33	nhr-4	F32B6.1	n/a	chrIV 9,880,614	nhr-4 is predicted to encode a nuclear hormone receptor (NHR); expression may peak during the late larval stages, based on mRNA expression analysis.
34	C48C5.1	C48C5.1	n/a	chrX 8,982,602	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002286 (P2 purinoceptor), IPR005390 (Neuromedin U receptor), IPR000276 (GPCR, rhodopsin-like)
35	tsg-101	C09G12.9	n/a	chrIV 3,512,510	C09G12.9 encodes the C. elegans ortholog of S. cerevisiae vacuolar protein sorting protein Vps23p and human TUMOR SUSCEPTIBILITY GENE 101 (TSG101; OMIM:601387), mutations in which are associated with several types of cancer and with varying responses to HIV infection; the product of C09G12.9 is predicted to be a component of C. elegans ESCRT-1 (Endosomal Sorting Complex Required for Transport), and RNAi experiments indicate that its activity is essential for embryonic and larval development.
36	ZK112.6	ZK112.6	n/a	chrIII 7,740,126	contains similarity to Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-sactivating enzyme).; SW:Q72LY9
37	W04D2.5	W04D2.5	n/a	chrV 12,493,975	contains similarity to Pfam domain PF00411 Ribosomal protein S11 contains similarity to Interpro domain IPR001971 (Ribosomal protein S11)
38	sos-1	T28F12.3	n/a	chrV 4,533,472	The sos-1 gene, also known as let-341, encodes an ortholog of Son of sevenless, a guanine nucleotide exchange factor that affects viability, sex myoblast migration, vulval induction, and oogenesis; it acts genetically downstream of let-23 and upstream of let-60 with respect to vulval development.
39	srd-42	R04D3.7	n/a	chrX 13,302,450	C. elegans SRD-42 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	dhs-27	C04F6.5	n/a	chrX 3,415,914	dhs-27 encodes a short-chain dehydrogenase predicted to be mitochondrial.
41	sre-31	F57G9.1	n/a	chrII 12,407,787	C. elegans SRE-31 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR), IPR000293 (Channel forming colicin, C-terminal cytotoxic)
42	K10H10.9	K10H10.9	n/a	chrII 14,514,333	contains similarity to Vibrio vulnificus Conserved hypothetical protein.; TR:Q8D6Y7
43	ZK643.7	ZK643.7	n/a	chrIII 8,925,977
44	F35E8.9	F35E8.9	n/a	chrV 15,916,920	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
45	srh-208	C43D7.6	n/a	chrV 19,317,895	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
46	ZK896.9	ZK896.9	n/a	chrIV 12,857,434	ZK896.9 encodes a putative transporter of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosamine (UDP-GalNAc), orthologous to human SLC35A3 (OMIM:605632) and paralogous to C03H5.2 and SRF-3; ZK896.9 has no obvious function in RNAi assays, but this could reflect genetic redundancy with its paralogs.
47	cyp-34A3	C41G6.1	n/a	chrV 15,229,059	C. elegans CYP-34A3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
48	C55B6.4	C55B6.4	n/a	chrX 7,187,869
49	acr-5	K03F8.2	n/a	chrIII 6,512,172	acr-5 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors that is expressed in the nervous system.
50	C12D12.4	C12D12.4	n/a	chrX 3,486,561