UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C04E12.12	C04E12.12	2e-164	chrV 3,390,139	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	W04C9.2	W04C9.2	n/a	chrI 489,263
4	rer-1	F46C5.8	n/a	chrII 8,811,744	C. elegans RER-1 protein; contains similarity to Pfam domain PF03248 Rer1 family contains similarity to Interpro domain IPR004932 (Retrieval of early ER protein Rer1)
5	F42A10.5	F42A10.5	n/a	chrIII 6,172,231	contains similarity to Interpro domain IPR003072 (Orphan nuclear receptor, NOR1 type)
6	glt-3	K08F4.4	n/a	chrIV 10,131,794	glt-3 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
7	elt-2	C33D3.1	n/a	chrX 10,482,266	elt-2 encodes a GATA-type transcription factor most similar to the vertebrate GATA4-6 transcription factors required for cardiac and endoderm development (OMIM:601656, 600576); in C. elegans, ELT-2 is required redundantly with ELT-7 for initiating and maintaining terminal differentiation of the intestine; ELT-2 is expressed solely in the intestine, beginning embryonically at the 2E-cell stage and continuing in all intestinal cells throughout the life of the animal; in the regulatory hierarchy controlling endoderm development, ELT-2 lies downstream of the maternal regulators SKN-1 and POP-1 and the embryonic GATA factors MED-1/-2, and END-1/-3; in turn, ELT-2, along with ELT-7, likely regulates transcription of a number of intestine-specific terminal differentiation genes such as ges-1, ifb-2, pha-4, and the stress-induced mtl-2; ELT-2 also positively autoregulates, presumably to ensure maintenance of intestinal differentiation
8	K04C1.4	K04C1.4	n/a	chrX 14,246,093	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
9	Y43F8C.4	Y43F8C.4	n/a	chrV 19,627,836	contains similarity to Homo sapiens 90 kDa protein; VG:OTTHUMP00000182483
10	B0554.2	B0554.2	n/a	chrV 435,748	contains similarity to Pfam domain PF02795 Domain of unknown function (DUF225) contains similarity to Interpro domain IPR004024 (Protein of unknown function DUF225)
11	F31A3.3	F31A3.3	n/a	chrX 17,533,568
12	ipp-5	C09B8.1	n/a	chrX 6,032,949	ipp-5 encodes a type I inositol 5-phosphatase homolog; ipp-5 acts downstream of let-23 to negatively regulate IP3 signaling and is involved in spermathecal contractions during ovulation; an ipp-5::gfp transcriptional reporter is expressed in the adult distal spermatheca and weakly in the proximal sheath.
13	gpr-2	C38C10.4	n/a	chrIII 9,392,118	gpr-2 encodes a protein containing a GPR (G Protein Regulator)/GoLoco motif characteristic of guanine nucleotide exchange factors specific for G-alpha GTPases; GPR-2 appears to function redundantly during early embryogenesis and germ-line development to regulate chromosome and spindle movements during cell division; GPR-2 likely acts as a positive regulator of G protein signaling and specifically, may regulate GOA-1 signaling in the embryo; GPR-2 forms a protein complex with the nearly identical GPR-1 and with LIN-5, a coiled-coil protein that is required for proper localization of GPR-2 to the cell cortex and spindle asters of the early embryo; in addition, proper GPR-2/GPR-1/LIN-5 localization between the P2 and EMS blastomeres at the four-cell stage, which may contribute to spindle positioning in EMS, requires the MES-1/SRC-1 tyrosine kinase signaling pathway; GPR-2 is believed to act downstream of, or in parallel to, PAR-3, a PDZ domain-containing protein, in mitotic spindle positioning in the early embryo.
14	F13D2.1	F13D2.1	n/a	chrX 11,169,479	contains similarity to Interpro domain IPR008930 (Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)
15	K08D10.10	K08D10.10	n/a	chrIV 4,155,758
16	gop-1	C34E10.3	n/a	chrIII 5,256,655	C. elegans GOP-1 protein; contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
17	nlt-1	ZK892.2	n/a	chrII 10,000,661	nlt-1 encodes a member of the SCP-2 sterol transfer family.
18	E01G6.1	E01G6.1	n/a	chrX 12,263,633	contains similarity to Pfam domains PF00027 (Cyclic nucleotide-binding domain) (2), PF01734 (Patatin-like phospholipase) contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin), IPR000595 (Cyclic nucleotide-binding), IPR001423 (Lysophospholipase patatin, conserved site), IPR014710 (RmlC-like jelly roll fold)
19	T20D4.6	T20D4.6	3e-98	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
20	cyp-35D1	F14H3.10	n/a	chrV 16,070,230	C. elegans CYP-35D1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR005837 (Flagellar transport protein FliP)
21	nspc-13	F42F12.6	n/a	chrX 12,357,636	C. elegans NSPC-13 protein ;
22	H34C03.2	H34C03.2	n/a	chrIV 6,759,933	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR006615 (Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)
23	dhp-2	C47E12.8	n/a	chrIV 9,979,451	The dhp-2 gene encodes an ortholog of the human gene DIHYDROPYRIMIDINASE (DPYS), which when mutated leads to dihydropyrimidinuria (OMIM:222748).
24	F13B6.2	F13B6.2	n/a	chrIV 7,459,793
25	ZK673.1	ZK673.1	n/a	chrII 10,444,162	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR003582 (Metridin-like ShK toxin)
26	twk-26	C33D12.3	n/a	chrX 3,052,381	C. elegans TWK-26 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
27	F16H6.10	F16H6.10	n/a	chrV 18,223,587	contains similarity to Haemophilus influenzae Putative protease HI0419 (EC 3.4.-.-).; SW:YEGQ_HAEIN
28	sulp-3	F41D9.5	n/a	chrX 8,405,893	sulp-3 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-3 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-3::GFP transcriptional fusion is expressed exclusively in the pharyngeal muscles.
29	str-48	C34D4.8	n/a	chrIV 7,123,053	C. elegans STR-48 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	ZK328.6	ZK328.6	n/a	chrIII 6,029,645	contains similarity to Pfam domains PF02818 (PPAK motif) , PF00646 (F-box domain) contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
31	F32B4.6	F32B4.6	n/a	chrI 11,516,108	contains similarity to Pfam domains PF07819 (PGAP1-like protein) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR012908 (PGAP1-like)
32	C05E11.7	C05E11.7	n/a	chrX 4,583,603
33	ZK593.1	ZK593.1	n/a	chrIV 10,911,466	contains similarity to Pfam domains PF02887 (Pyruvate kinase, alpha/beta domain) , PF00224 (Pyruvate kinase, barrel domain) contains similarity to Interpro domains IPR015806 (Pyruvate kinase, beta-barrel), IPR015794 (Pyruvate kinase, alpha/beta), IPR015795 (Pyruvate kinase, C-terminal-like), IPR015813 (Pyruvate/Phosphoenolpyruvate kinase, catalytic core), IPR001697 (Pyruvate kinase), IPR015793 (Pyruvate kinase, barrel)
34	F53F1.3	F53F1.3	n/a	chrV 13,409,019	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
35	clk-2	C07H6.6	n/a	chrIII 7,516,797	The clk-2 gene encodes an ortholog of the S. cerevisiae telomere length-regulating protein Tel2p that has been shown to bind a number of DNA structures in vitro, including single-, double- and four-stranded DNA; in C. elegans, CLK-2 activity is required for the DNA damage and S phase replication checkpoints, for embryonic development, and for normal biological rhythms and life span; a functional CLK-2::GFP fusion protein is detected exclusively in the cytoplasm of somatic tissues.
36	math-35	R52.3	n/a	chrII 2,105,696	C. elegans MATH-35 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
37	C46G7.2	C46G7.2	n/a	chrIV 6,016,483	contains similarity to Anisakis simplex 29kDa protein from Anisakis simplex.; TR:Q9U5Z9
38	K02G10.5	K02G10.5	n/a	chrX 4,689,524	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF03137 (Organic Anion Transporter Polypeptide (OATP) family) contains similarity to Interpro domains IPR004156 (Organic anion transporter polypeptide OATP), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
39	tag-51	K02F3.1	n/a	chrIII 855,363	C. elegans TAG-51 protein ;
40	R08D7.7	R08D7.7	n/a	chrIII 8,993,437	contains similarity to Pfam domains PF02782 (FGGY family of carbohydrate kinases, C-terminal domain) , PF00370 (FGGY family of carbohydrate kinases, N-terminal domain) contains similarity to Interpro domain IPR000577 (Carbohydrate kinase, FGGY)
41	sgcb-1	K01A2.1	n/a	chrII 327,229	K01A2.1 is orthologous to the human gene SARCOGLYCAN, BETA (43KD DYSTROPHIN-ASSOCIATED GLYCOPROTEIN) (SGCB; OMIM:600900), which when mutated leads to disease.
42	rab-11.1	F53G12.1	n/a	chrI 109,369	rab-11.1 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; RAB-11.1 activity is required for completion of the final stages of cytokinesis during early embryogenesis and for efficient uptake of yolk proteins during oocyte development; RAB-11.1 is also required for normal peripheral localization of nuclei in the synctial germ cell in the ovary.
43	D1014.7	D1014.7	n/a	chrV 8,119,293	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
44	Y54G11A.4	Y54G11A.4	n/a	chrII 14,294,300	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR000023 (Phosphofructokinase)
45	F13D12.8	F13D12.8	n/a	chrII 11,731,826	contains similarity to White spot syndrome virus WSSV473 (Major virion protein VP19).; TR:Q8QTB2
46	F19C7.2	F19C7.2	n/a	chrIV 4,601,343	contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domain IPR008758 (Peptidase S28)
47	fbxa-31	ZC47.5	n/a	chrIII 1,270,493	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
48	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
49	ZK488.6	ZK488.6	n/a	chrV 591,473	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
50	F38A1.8	F38A1.8	n/a	chrIV 1,236,362	contains similarity to Pfam domains PF00448 (SRP54-type protein, GTPase domain) , PF02881 (SRP54-type protein, helical bundle domain) , PF04086 (Signal recognition particle, alpha subunit, N-terminal) contains similarity to Interpro domains IPR007222 (Signal recognition particle receptor, alpha subunit, N-terminal), IPR000897 (Signal recognition particle, SRP54 subunit, GTPase), IPR011012 (Longin-like), IPR013822 (Signal recognition particle, SRP54 subunit, helical bundle), IPR003593 (AAA+ ATPase, core)