UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	lips-2	C04B4.3	0	chrX 12,286,461	C. elegans LIPS-2 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
2	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
3	T02H6.4	T02H6.4	n/a	chrII 690,572	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
4	T22B2.7	T22B2.7	n/a	chrX 3,909,459
5	C08G5.2	C08G5.2	n/a	chrII 740,228
6	F47B3.4	F47B3.4	n/a	chrI 3,961,620	contains similarity to Pfam domain PF03057 Protein of unknown function contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR003267 (Small proline-rich), IPR004296 (Protein of unknown function DUF236), IPR000694 (Proline-rich region), IPR001399 (VP6 blue-tongue virus inner capsid protein), IPR000079 (High mobility group protein HMG14 and HMG17)
7	W06F12.3	W06F12.3	n/a	chrIII 13,735,661	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
8	F23B12.1	F23B12.1	n/a	chrV 14,429,754	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
9	W01B11.1	W01B11.1	n/a	chrI 3,300,049	contains similarity to Interpro domain IPR000694 (Proline-rich region)
10	K02A11.2	K02A11.2	n/a	chrI 9,745,095	contains similarity to Saccharomyces cerevisiae Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis; SGD:YGR159C
11	grl-2	T16G1.8	n/a	chrV 12,945,836	grl-2 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-2 is expressed in neurons, amphid socket cells, and other cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
12	nas-5	T23H4.3	n/a	chrI 9,887,167	nas-5 encodes an astacin-like metalloprotease; loss of nas-5 activity in an RNAi hypersensitive strain results in axon guidance defects, including a failure of DD/VD motoneuron commissures to reach the dorsal cord, defasciculation of the dorsal nerve cord, and midline crossing defects in the ventral nerve cord.
13	try-7	ZC581.6	n/a	chrI 6,642,054	C. elegans TRY-7 protein; contains similarity to Pfam domains PF00089 (Trypsin) , PF03761 (Domain of unknown function (DUF316)) contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
14	W01D2.3	W01D2.3	n/a	chrII 14,802,515	contains similarity to Haemophilus influenzae Electron transport complex protein rnfD.; SW:RNFD_HAEIN
15	H04M03.11	H04M03.11	n/a	chrIV 5,883,356
16	C08E8.3	C08E8.3	n/a	chrV 18,351,418	contains similarity to Clostridium perfringens Probable Ser-type protease.; TR:Q8XHC4
17	F09E8.1	F09E8.1	n/a	chrIV 13,141,838	contains similarity to Pfam domain PF01666 DX module contains similarity to Interpro domains IPR011052 (Proteinase and amylase inhibitor), IPR002593 (Protein of unknown function DX)
18	ZK353.3	ZK353.3	n/a	chrIII 8,396,275
19	spe-9	C17D12.6	n/a	chrI 11,584,385	spe-9 encodes an EGF repeat-containing protein with a short intracellular domain; SPE-9 is required autonomously in sperm for fertilization, and by homology, likely mediates an adhesive or signaling event necessary for proper oocyte fertilization; spe-9 mRNA is detected solely in animals that are engaged in spermatogenesis; in spermatids, SPE-9 is found at or near the cell surface; following sperm activation, SPE-9 is found primarily on the pseudopod.
20	C25A8.5	C25A8.5	n/a	chrIV 7,000,530	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
21	srv-12	T04B2.4	n/a	chrIV 10,052,440	C. elegans SRV-12 protein ;
22	scrm-8	K08D10.7	n/a	chrIV 4,165,432	scrm-8 encodes a putative phospholipid scramblase required for normally short lifespan; SCRM-8 is homologous to human PLSCR1-5, and paralogous to other C. elegans SCRMs (e.g., SCRM-1).
23	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
24	C48E7.8	C48E7.8	n/a	chrI 6,267,364	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
25	ttr-6	T28B4.3	n/a	chrX 6,596,773	C. elegans TTR-6 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
26	clec-135	C16A11.8	n/a	chrII 4,257,930	C. elegans CLEC-135 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
27	C10G11.10	C10G11.10	n/a	chrI 6,305,695
28	H32C10.3	H32C10.3	n/a	chrIV 5,918,692	contains similarity to Pfam domains PF00023 (Ankyrin repeat) (5), PF01529 (DHHC zinc finger domain) contains similarity to Interpro domains IPR001594 (Zinc finger, DHHC-type), IPR002110 (Ankyrin)
29	srg-46	F32H5.5	n/a	chrV 13,364,203	C. elegans SRG-46 protein ;
30	T10E9.6	T10E9.6	n/a	chrI 6,529,637	contains similarity to Pfam domain PF03134 TB2/DP1, HVA22 family contains similarity to Interpro domain IPR004345 (TB2/DP1 and HVA22 related protein)
31	F23C8.1	F23C8.1	n/a	chrI 2,447,555
32	trf-1	F45G2.6	n/a	chrIII 13,431,808	The trf-1 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
33	F23C8.8	F23C8.8	n/a	chrI 2,431,177	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
34	H32C10.1	H32C10.1	n/a	chrIV 5,935,928	contains similarity to Interpro domains IPR006353 (HAD-superfamily hydrolase, subfamily IIA, CECR5), IPR006357 (HAD-superfamily hydrolase, subfamily IIA)
35	str-86	F59E11.14	n/a	chrV 8,983,013	C. elegans STR-86 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	M28.9	M28.9	n/a	chrII 10,641,581	contains similarity to Homo sapiens hypothetical protein; VG:OTTHUMP00000024599
37	K01D12.15	K01D12.15	n/a	chrV 12,386,487	contains similarity to Interpro domains IPR001859 (Ribosomal protein P2), IPR000976 (Wilm's tumour protein)
38	Y7A5A.8	Y7A5A.8	n/a	chrX 15,823,201	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IL30
39	tag-191	C53A5.4	n/a	chrV 14,535,355	C. elegans TAG-191 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
40	ncl-1	ZK112.2	n/a	chrIII 7,734,657	ncl-1 encodes a cytoplasmic B-box zinc finger protein that negatively regulates rRNA and 5S RNA transcription, nucleolus size, and body size; NCL-1 is orthologous to Drosophila BRAIN TUMOR (BRAT), and ncl-1 mutants can be rescued by brat transgenes; NCL-1 is required for the normally small size of neuronal, muscle, and hypodermal nucleoli, and is already active in 4-cell embryos; NCL-1 may be a repressor of RNA polymerase I and III transcription and an inhibitor of cell growth, based on mutant analysis; ncl-1 animals have much larger neuronal nucleoli than normal, somewhat larger muscle and hypodermal nucleoli, but essentially normal intestinal and germline nucleoli (the last of which are large even in wild-type animals); conversely, intestinal and germline cells have the lowest amounts of NCL-1 protein; ncl-1 animals are 9% larger, have 22% more protein and twice as much rRNA, and transcribe rRNA twice as much as wild-type worms; ncl-1 functions cell autonomously, and ncl-1 mutations suppress the tumorous germline phenotype of pro-1(na48) mutants.
41	tba-6	F32H2.9	n/a	chrI 8,996,289	C. elegans TBA-6 protein; contains similarity to Pfam domains PF00091 (Tubulin/FtsZ family, GTPase domain) , PF03953 (Tubulin/FtsZ family, C-terminal domain) contains similarity to Interpro domains IPR002454 (Gamma tubulin), IPR002452 (Alpha tubulin), IPR002453 (Beta tubulin), IPR000217 (Tubulin), IPR003008 (Tubulin/FtsZ, GTPase), IPR004057 (Epsilon tubulin), IPR002967 (Delta tubulin), IPR000158 (Cell division protein FtsZ, N-terminal), IPR008280 (Tubulin/FtsZ, C-terminal)
42	C24D10.1	C24D10.1	n/a	chrIV 5,167,373	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
43	C17C3.11	C17C3.11	n/a	chrII 5,538,392	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
44	D2062.6	D2062.6	n/a	chrII 2,619,582	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
45	C15H11.1	C15H11.1	n/a	chrV 14,394,129	contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
46	K05F1.5	K05F1.5	n/a	chrII 5,791,755	contains similarity to Pfam domain PF01551 Peptidase family M23 contains similarity to Interpro domains IPR016047 (Peptidase M23), IPR008663 (Leukocyte cell-derived chemotaxin 2), IPR011055 (Duplicated hybrid motif)
47	F07E5.4	F07E5.4	n/a	chrII 2,050,852
48	T19D7.5	T19D7.5	n/a	chrX 665,501
49	scrm-6	F46A8.10	n/a	chrI 11,254,608	scrm-6 encodes a putative phospholipid scramblase homologous to human PLSCR1-5, and paralogous to other C. elegans SCRMs (e.g., SCRM-1); scrm-6(RNAi) animals have no obvious phenotype.
50	Y48E1C.3	Y48E1C.3	n/a	chrII 13,439,410	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)