UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C04B4.2	C04B4.2	0	chrX 12,284,223	contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
2	F54D10.7	F54D10.7	n/a	chrII 3,820,711	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
3	fbxa-170	C36C9.3	n/a	chrX 1,677,298	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
4	C50E3.13	C50E3.13	n/a	chrV 7,623,254
5	C16A3.2	C16A3.2	n/a	chrIII 6,390,183	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
6	F41C6.3	F41C6.3	n/a	chrX 6,870,780
7	fut-3	F59E12.13	n/a	chrII 5,658,783	C. elegans FUT-3 protein; contains similarity to Pfam domain PF00852 Glycosyltransferase family 10 (fucosyltransferase) contains similarity to Interpro domain IPR001503 (Glycosyl transferase, family 10)
8	E02H4.6	E02H4.6	n/a	chrX 14,251,350	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
9	C27C12.3	C27C12.3	n/a	chrX 14,864,682	C27C12.3 encodes a novel protein that is conserved in C. elegans; three other genes related to C27C12.3 are present in tandem on the X chromosome; in situ hybridization studies indicate that C27C12.3 mRNA is expressed in the proximal germline.
10	F43G6.10	F43G6.10	n/a	chrII 11,809,738	contains similarity to Interpro domain IPR000694 (Proline-rich region)
11	F52B5.2	F52B5.2	n/a	chrI 8,317,068	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
12	F31F6.3	F31F6.3	n/a	chrX 14,872,269	F31F6.3 encodes a novel protein that is conserved in C. elegans; three other genes related to F31F6.3 are present in tandem on the X chromosome.
13	meg-1	K02B9.1	n/a	chrX 13,928,257	meg-1 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-1 activity via mutation and RNAi indicates that MEG-1 is required for germline development and normal levels of fertility; specifically, MEG-1 is required maternally for normal germ cell proliferation and/or survival and for fully normal P granule segregation to the germ cell lineage; in regulating germline development, meg-1 likely functions redundantly with meg-2 and mes-1; meg-1 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; meg-1 mRNA is expressed in the proximal germline; MEG-1 localizes to P granules from the 4-to-8-cell through 100-cell stage of embryogenesis; MEG-1 localization to P granules partially requires MES-1 and, in turn, MES-1 localization to P granules is partly dependent on MEG-1.
14	W06D11.5	W06D11.5	n/a	chrX 12,300,631	contains similarity to Homo sapiens Hypothetical protein KIAA1801; ENSEMBL:ENSP00000256007
15	B0393.3	B0393.3	n/a	chrIII 4,758,450	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR006553 (Leucine-rich repeat, cysteine-containing subtype)
16	F32D1.6	F32D1.6	n/a	chrV 4,374,245
17	tag-319	C30B5.1	n/a	chrII 6,200,135	C. elegans TAG-319 protein ;
18	C18A3.1	C18A3.1	n/a	chrII 5,720,938	contains similarity to Pfam domain PF05063 MT-A70 contains similarity to Interpro domains IPR007757 (MT-A70), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
19	fem-3	C01F6.4	n/a	chrIV 9,106,267	fem-3 encodes a novel protein that promotes male development in all tissues.
20	nos-1	R03D7.7	n/a	chrII 10,952,444	nos-1 encodes an putative RNA-binding protein that contains a zinc-binding motif homologous to that of Drosophila Nanos, a posterior-group protein required for embryonic patterning and primordial germ cell development; in C. elegans, NOS-1 is required redundantly with NOS-2, a second Nanos homolog, for maintenance of germ cell viability during postembryonic development and for preventing primordial germ cells from dividing in the absence of food; nos-1 mRNA is expressed dynamically in the embryo, with early expression seen throughout the embryo and later expression restricted solely to germline blastomeres; nos-1 mRNA becomes undetectable after the 200-cell stage, but reappears later at the 550-cell stage; NOS-1 protein is not detectable in germline blastomeres until the 550-cell stage, suggesting that NOS-1 might actually function zygotically in germline specification.
21	C31H1.8	C31H1.8	n/a	chrIV 5,812,882	contains similarity to Homo sapiens Protocadherin 15; ENSEMBL:ENSP00000378832
22	ZC477.5	ZC477.5	n/a	chrIV 7,102,332
23	F40F11.3	F40F11.3	n/a	chrIV 11,592,569	contains similarity to Saccharomyces cerevisiae involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi; SGD:YDL058W
24	R02F2.4	R02F2.4	n/a	chrIII 5,485,028	R02F2.4 encodes a protein with six chitin-binding peritrophin-A domains; R02F2.4 transcripts are enriched during oogenesis; like CEJ-1 and CPG-2, R02F2.4 might participate in eggshell synthesis and early embryonic development, and R02F2.4's multiple peritrophin-A domains might enable mechanical cross-linking of chitin; however, R02F2.4 has no obvious function in mass RNAi assays; while R02F2.4 is more closely similar to CPG-2 than CEJ-1, it may be less strongly expressed (since it has substantially fewer ESTs) and thus be less important in development.
25	meg-2	K02B9.2	n/a	chrX 13,924,518	meg-2 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-2 activity by itself results in no obvious abnormalities, but loss of meg-2 activity in meg-1 mutant animals indicates that meg-1 and meg-2 likely have redundant functions in germline development; meg-2 may also function redundantly with mes-1; meg-2 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; a GFP::MEG-2 fusion protein localizes exclusively to P granules in the embryonic germ cell lineage.
26	C27D9.1	C27D9.1	n/a	chrII 4,754,512	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
27	nhr-263	F10G2.9	n/a	chrV 7,341,043	C. elegans NHR-263 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
28	F31B9.3	F31B9.3	n/a	chrX 15,924,034	contains similarity to Homo sapiens Similar to polymerase (RNA) III; ENSEMBL:ENSP00000334758
29	Y57G11B.5	Y57G11B.5	n/a	chrIV 14,575,666
30	T09B4.1	T09B4.1	n/a	chrI 6,186,762	contains similarity to Pfam domain PF04188 Mannosyltransferase (PIG-V)) contains similarity to Interpro domain IPR007315 (Mannosyltransferase, PIG-V)
31	R53.6	R53.6	n/a	chrII 9,969,060	contains similarity to Pfam domain PF03651 Partner of SLD five, PSF1 contains similarity to Interpro domain IPR005339 (GINS complex, Psf1 component)
32	C36C9.1	C36C9.1	n/a	chrX 1,684,665	contains similarity to Dictyostelium discoideum Similar to Homo sapiens (Human). Dentin sialophosphoprotein [Contains:sDentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentinssialoprotein (DSP)].; TR:Q869X8
33	F54D10.5	F54D10.5	n/a	chrII 3,807,652
34	try-1	ZK546.15	n/a	chrII 4,948,807	C. elegans TRY-1 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine), IPR008256 (Peptidase S1B, glutamyl endopeptidase I)
35	bath-41	F37A4.9	n/a	chrIII 6,721,274	The F37A4.9 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
36	K08H2.3	K08H2.3	n/a	chrX 13,237,815	contains similarity to Rattus norvegicus Inositol 1,4,5-trisphosphate 3-kinase C.; TR:Q80ZG2
37	C25A11.1	C25A11.1	n/a	chrX 9,120,170
38	F28C6.2	F28C6.2	n/a	chrII 8,595,158	F28C6.2 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.1, which lies adjacent to F28C6.1 on chromosome II; loss of F28C6.2 activity via large-scale RNAi results in some embryonic lethality and low levels of larval arrest, body morphology defects, and uncoordinated locomotion.
39	C29G2.1	C29G2.1	n/a	chrV 2,591,466
40	mxl-1	T19B10.11	n/a	chrV 11,245,345	mxl-1 encodes a basic helix-loop-helix protein similar to the vertebrate MAX transcriptional regulators; in vitro, MXL-1 can heterodimerize, and bind an E-box DNA sequence, with MDL-1, a C. elegans MAD-like bHLH protein; mxl-1::gfp reporter fusions are expressed in the posterior intestine and in head and tail neurons.
41	rgs-10	F45B8.2	n/a	chrX 14,963,378	C. elegans RGS-10 protein; contains similarity to Pfam domain PF00615 Regulator of G protein signaling domain contains similarity to Interpro domains IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
42	sru-48	T03G11.2	n/a	chrX 5,180,802	C. elegans SRU-48 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
43	C02B10.2	C02B10.2	n/a	chrIV 5,090,651	contains similarity to Homo sapiens SNARE-associated protein Snapin; ENSEMBL:ENSP00000357674
44	kca-1	C10H11.10	n/a	chrI 4,760,571	C. elegans KCA-1 protein ;
45	C49C8.3	C49C8.3	n/a	chrIV 8,644,987
46	C17F4.5	C17F4.5	n/a	chrII 3,247,215	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
47	E02H9.7	E02H9.7	n/a	chrIII 2,445,442	contains similarity to Homo sapiens Uncharacterized protein MUC17 (Fragment); ENSEMBL:ENSP00000368750
48	F54F7.6	F54F7.6	n/a	chrX 11,866,107	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
49	F11C1.2	F11C1.2	n/a	chrX 12,986,446	contains similarity to Lactococcus lactis Rgg protein, putative.; TR:O87251
50	rmd-1	T05G5.7	n/a	chrIII 9,759,548	C. elegans RMD-1 protein; contains similarity to Interpro domain IPR011990 (Tetratricopeptide-like helical)