UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C03D6.6	C03D6.6	5e-79	chrI 9,657,459	contains similarity to Saccharomyces cerevisiae Involved in cell cycle control and ion homeostasis; SGD:YKR072C
2	H02I12.1	H02I12.1	n/a	chrIV 11,375,266	H02I12.1 encodes a large (1319-residue) protein with 12 chitin-binding peritrophin-A domains; H02I12.1(RNAi) animals have an osmotically-sensitive embryonic lethal phenotype, perhaps because of defects in chitin and eggshell synthesis; like CEJ-1 and CPG-2, H02I12.1 may participate in eggshell synthesis and early embryonic development; H02I12.1's multiple peritrophin-A domains might enable mechanical cross-linking of chitin.
3	C16C8.4	C16C8.4	n/a	chrII 3,443,969	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
4	C37C3.9	C37C3.9	n/a	chrV 7,853,081	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
5	C16A11.6	C16A11.6	n/a	chrII 4,237,141
6	gln-6	C28D4.3	n/a	chrIV 9,740,184	C. elegans GLN-6 protein; contains similarity to Pfam domains PF03951 (Glutamine synthetase, beta-Grasp domain) , PF00120 (Glutamine synthetase, catalytic domain) contains similarity to Interpro domains IPR008147 (Glutamine synthetase, beta-Grasp), IPR014746 (Glutamine synthetase/guanido kinase, catalytic region), IPR008146 (Glutamine synthetase, catalytic region)
7	F58A4.2	F58A4.2	n/a	chrIII 9,600,293	contains similarity to Musca domestica Hexamerin (Fragment).; TR:Q9U6B2
8	vha-18	F52E1.10	n/a	chrV 8,412,615	vha-18 encodes an an ortholog of subunit H of the cytoplasmic (V1) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-18 and VHA-15 are co-orthologs; VHA-18 is a predicted cytosolic stator (stalk) component.
9	F29C4.6	F29C4.6	n/a	chrIV 120,551	contains similarity to Pfam domain PF01171 PP-loop family contains similarity to Interpro domains IPR011063 (PP-loop), IPR012089 (PP-loop ATPase, YdaO-related), IPR000541 (Protein of unknown function UPF0021), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold)
10	btb-7	F45C12.12	n/a	chrII 1,713,745	C. elegans BTB-7 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
11	ZC581.3	ZC581.3	n/a	chrI 6,653,325	contains similarity to Interpro domain IPR011046 (WD40 repeat-like)
12	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
13	C16C10.3	C16C10.3	n/a	chrIII 4,174,219	contains similarity to Pfam domains PF02170 (PAZ domain) , PF02171 (Piwi domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
14	F33E11.2	F33E11.2	n/a	chrV 298,304	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003980 (Histamine H3 receptor)
15	sdz-27	R07H5.4	n/a	chrIV 11,187,603	C. elegans SDZ-27 protein
16	F35C11.5	F35C11.5	n/a	chrII 8,254,199	contains similarity to Interpro domains IPR016090 (Phospholipase A2), IPR013090 (Phospholipase A2, active site)
17	B0244.9	B0244.9	n/a	chrIII 5,730,515	contains similarity to Interpro domains IPR005838 (Type III secretion system inner membrane P protein), IPR001865 (Ribosomal protein S2)
18	K03H4.2	K03H4.2	n/a	chrV 13,153,453	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:O96209
19	mex-6	AH6.5	n/a	chrII 9,525,192	mex-6 encodes a CCCH zinc-finger protein highly similar to MEX-5 that functions with MEX-5 to affect embryonic viability, establish soma germline asymmetry in embryos and establish PIE-1, MEX-1, and POS-1 asymmetry in embryos, and also affects formation of intestinal cells; MEX-6 and MEX-5 may act downstream of the PAR proteins.
20	mex-5	W02A2.7	n/a	chrIV 13,354,881	mex-5 encodes a novel protein that contains two CCCH zinc finger motifs; maternally provided MEX-5, which functions partly redundantly with the highly similar CCCH finger protein MEX-6, is essential for transducing polarity cues and establishing soma/germline asymmetry in the early embryo; in regulating soma/germline asymmetry, MEX-5 interacts with, and activates, the SOCS-box protein ZIF-1, which functions as part of an E3 ubiquitin ligase complex that degrades germ plasm proteins in somatic blastomeres; accordingly, ectopic expression of MEX-5 throughout the early embryo results in reduced expression of germline proteins in germline blastomeres; MEX-5 is a cytoplasmic protein expressed at uniform levels in oocytes and newly fertilized eggs; from the 1-cell to 4-cell stages of embryogenesis, MEX-5 expression is dynamic, with highest levels seen in the anterior AB blastomere and, for a time, its daughters, the anterior portion of the P1 blastomere, P1 centrosomes (both, then posterior only), and the EMS and C blastomeres; the asymmetric distribution of MEX-5 in early embryos depends upon wild-type activity of the PAR and OMA-1 proteins.
21	K07A1.13	K07A1.13	n/a	chrI 9,584,354	contains similarity to White spot syndrome virus Wsv319.; TR:Q8VAS3
22	syp-2	C24G6.1	n/a	chrV 5,537,191	C. elegans SYP-2 protein ;
23	srj-25	C05E4.10	n/a	chrV 735,347	C. elegans SRJ-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
24	pax-3	F27E5.2	n/a	chrII 10,149,568	pax-3 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; PAX-3 is required for locomotion and vulval development; pax-3(RNAi) animals have consistent Pvl and Unc phenotypes (as well as less consistent Bmd, Rup, and Stp phenotypes).
25	F31E3.6	F31E3.6	n/a	chrIII 6,982,722
26	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
27	D1086.7	D1086.7	n/a	chrV 14,084,866	contains similarity to Synechocystis sp Hypothetical protein slr1028.; TR:P73139
28	cpar-1	F54C8.2	n/a	chrIII 9,434,486	cpar-1 encodes one of two C. elegans proteins homologous to the inner kinetochore histone H3 variant CENP-A (the other is encoded by hcp-3); loss of cpar-1 and hcp-3 activity via RNAi results in mitotic chromosome segregation defects, but no significant defects in meiotic chromosome segregation; when expressed in the germline using the pie-1 promoter, a CPAR-1::GFP fusion protein localizes to meiotic chromosomes during late prophase/prometaphase of meiosis I, but is not seen on chromosomes during meiosis II.
29	str-182	C12D8.12	n/a	chrV 10,232,595	C. elegans STR-182 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
31	F47B8.6	F47B8.6	n/a	chrV 14,329,569	contains similarity to Drosophila heteroneura Aminopeptidase N (Fragment).; TR:O61534
32	rnp-8	R119.7	n/a	chrI 366,516	C. elegans RNP-8 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
33	K08F4.3	K08F4.3	n/a	chrIV 10,129,732	contains similarity to Pfam domain PF05753 Translocon-associated protein beta (TRAPB) contains similarity to Interpro domain IPR008856 (Translocon-associated beta)
34	C14B1.9	C14B1.9	n/a	chrIII 3,725,339	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000307805
35	F32D1.7	F32D1.7	n/a	chrV 4,375,562	contains similarity to Interpro domain IPR005405 (Potassium channel, voltage dependent, Kv3.4)
36	T09F5.10	T09F5.10	n/a	chrV 15,180,897	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
37	K07A1.1	K07A1.1	n/a	chrI 9,583,089	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IBJ6
38	srbc-29	C02A12.2	n/a	chrV 3,470,161	C. elegans SRBC-29 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
39	F57C2.3	F57C2.3	n/a	chrII 14,524,512	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000265391
40	F56C9.3	F56C9.3	n/a	chrIII 7,312,130	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)
41	C03G6.5	C03G6.5	n/a	chrV 7,365,571	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
42	mei-2	F57B10.12	n/a	chrI 6,565,308	mei-2 encodes a novel protein that contains a region similar to the p80-targeting subunit of katanin that is required for embryonic viability, alignment of chromosomes at the metaphase plate, and establishment of the oocyte meiotic spindle together with MEI-1; can interact with MEI-1 in HeLa cells and this complex can function to disassemble microtubules, expressed in the germ line, throughout the cytoplasm of most mature oocytes within the proximal gonad, and localization is mutually dependent upon MEI-1
43	W02B12.4	W02B12.4	n/a	chrII 11,457,473	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
44	C48B4.9	C48B4.9	n/a	chrIII 9,562,829	contains similarity to Arabidopsis thaliana Hypothetical protein (At1g32400/F5D14_22) (Tobamovirus multiplications2A).; TR:Q9C5W7
45	F43G9.4	F43G9.4	n/a	chrI 8,611,732	contains similarity to Brugia malayi Putative uncharacterized protein BMBAC01P19.03a.; TR:Q8IHI9
46	T25C8.1	T25C8.1	n/a	chrIII 13,611,268	contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000577 (Carbohydrate kinase, FGGY)
47	C38D4.4	C38D4.4	n/a	chrIII 4,794,206	contains similarity to Saccharomyces cerevisiae Delayed Anaerobic Gene; SGD:YJR151C
48	W02D9.5	W02D9.5	n/a	chrI 12,561,291	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
49	R09B3.2	R09B3.2	n/a	chrI 11,909,721	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
50	nos-2	ZK1127.1	n/a	chrII 7,066,218	nos-2 encodes one of three genes in C. elegans that contains a putative zinc-binding domain similar to the one found in Drosophila nanos; nos-2 affects incorporation of primordial germ cells into the somatic gonad, is required redundantly with nos-1 to prevent primordial germ cells from dividing in starved animals and to maintain germ cell viability during larval development in hermaphrodites and in males, and also functions together with nos-1 and nos-3 in the hermaphrodite switch from spermatogenesis to oogenesis; nos-2 is expressed in the primordial germ cells around the time of gastrulation from a maternal RNA associated with P granules, and it is expressed coordinately with nos-1in a dynamic fashion until the embryonic 200-cell stage.