UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	jud-4	C02D4.1	1e-150	chrX 15,285,194	jud-4 encodes an unfamiliar protein, putatively secreted, that is required both for normal sensitivity to ethanol and for survival after freezing and thawing; JUD-4 is expressed in hypodermis and vulval muscles; JUD-4 is orthologous to Brugia malayi Bm1_40315, but lacks obvious orthologies to non-nematode proteins; JUD-4's C-terminal domain has possible similarity to F40E10.5, and to proteins such as human HOMER1; jud-4(ys18) mutants show delayed sensitivity to ethanol levels that rapidly paralyze normal worms, but do not survive freezing and rethawing as does wild-type; JUD-4 has no obvious function in mass RNAi assays.
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	col-152	F32G8.5	n/a	chrV 10,561,507	C. elegans COL-152 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
4	T06A1.5	T06A1.5	n/a	chrV 1,929,299	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
5	F26G1.5	F26G1.5	n/a	chrII 4,770,962	contains similarity to Pfam domain PF01682 DB module contains similarity to Interpro domain IPR002602 (Protein of unknown function DB)
6	cpin-1	F38E11.3	n/a	chrIV 9,452,280	cpin-1 is orthologous to a mammalian protein variously identified as guanine aminohydrolase (or guanine deaminase, or guanase), cypin, or p51-nedasin.
7	T06E4.8	T06E4.8	n/a	chrV 9,622,529	contains similarity to Interpro domain IPR000694 (Proline-rich region)
8	F20G2.2	F20G2.2	n/a	chrV 13,755,695	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
9	his-33	F17E9.13	n/a	chrIV 8,335,508	his-33 encodes an H2A histone; by homology, HIS-33 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-33 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
10	K08H10.6	K08H10.6	n/a	chrV 9,994,779	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
11	T06D8.10	T06D8.10	n/a	chrII 11,244,135	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal), IPR001007 (von Willebrand factor, type C)
12	drr-1	F45H10.4	n/a	chrII 13,495,384	C. elegans DRR-1 protein; contains similarity to Interpro domain IPR008253 (Marvel)
13	rap-3	C08F8.7	n/a	chrIV 11,177,654	C. elegans RAP-3 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily)
14	C29F7.1	C29F7.1	n/a	chrX 13,413,508	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
15	nas-7	C07D10.4	n/a	chrII 7,401,654	nas-7 encodes an astacin-like metalloprotease; a NAS-7::GFP reporter fusion is first expressed in embryos just prior to hatching and, in adult animals, is seen in anterior cells adjacent to the pharyngeal metacarpus and terminal bulb.
16	C42D4.3	C42D4.3	n/a	chrIV 7,179,810	contains similarity to Pfam domain PF01682 DB module contains similarity to Interpro domain IPR002602 (Protein of unknown function DB)
17	lact-8	Y42A5A.2	n/a	chrV 11,092,342	lact-8 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.
18	H41C03.3	H41C03.3	n/a	chrII 5,848,949	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
19	Y70C5A.2	Y70C5A.2	n/a	chrV 16,622,275	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	his-39	F45F2.2	n/a	chrV 8,536,492	his-39 encodes an H2B histone; by homology, HIS-39 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; loss of his-39 function via RNA-mediated interference (RNAi) does not result in any abnormalities; his-39 is a replication-dependent histone locus that resides in the HIS2 cluster on chromosome V.
21	W06A7.2	W06A7.2	n/a	chrV 14,822,585	contains similarity to Salmonella typhi;Salmonella typhimurium Hypothetical protein (Putative inner membrane protein).; TR:Q8XEW6
22	tomm-7	ZK652.2	n/a	chrIII 7,859,778	C. elegans TOMM-7 protein; contains similarity to Pfam domain PF08038 TOM7 family contains similarity to Interpro domain IPR012621 (Mitochondrial import translocase, subunit Tom7)
23	F07C6.2	F07C6.2	n/a	chrIV 12,791,374	contains similarity to Amblyomma hebraeum 9.8 kDa basic protein.; TR:Q9GPM1
24	C27A2.5	C27A2.5	n/a	chrII 5,069,164	contains similarity to Interpro domains IPR000006 (Metallothionein, vertebrate), IPR002952 (Eggshell protein), IPR006081 (Alpha defensin), IPR001396 (Echinodermata metallothionein, family 4), IPR001008 (Mollusc metallothionein, family 2)
25	K01D12.8	K01D12.8	n/a	chrV 12,402,922	contains similarity to Xenopus tropicalis Splicing factor, arginine/serine-rich 1.; SW:Q6DII2
26	srx-29	K06B4.9	n/a	chrV 15,697,466	C. elegans SRX-29 protein ;
27	B0205.8	B0205.8	n/a	chrI 10,729,585	contains similarity to Homo sapiens hypothetical protein LOC25940; ENSEMBL:ENSP00000238823
28	R07E4.3	R07E4.3	n/a	chrX 5,953,576	contains similarity to Pfam domain PF02939 UcrQ family contains similarity to Interpro domain IPR004205 (UcrQ)
29	M195.2	M195.2	n/a	chrII 8,362,076	contains similarity to Pfam domain PF02363 Cysteine rich repeat
30	F49E12.10	F49E12.10	n/a	chrII 8,391,583	contains similarity to Pfam domain PF01598 contains similarity to Interpro domain IPR006088 (Sterol desaturase)
31	F13B12.2	F13B12.2	n/a	chrIV 10,427,657	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001991 (Sodium:dicarboxylate symporter), IPR001411 (Tetracycline resistance protein, TetB), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
32	T08B2.8	T08B2.8	n/a	chrI 6,211,579	contains similarity to Interpro domain IPR012678 (Ribosomal protein L23/L15e, core)
33	T28C12.6	T28C12.6	n/a	chrV 6,335,928	contains similarity to Pfam domain PF00095 WAP-type (Whey Acidic Protein) 'four-disulfide core' contains similarity to Interpro domain IPR008197 (Whey acidic protein, 4-disulphide core)
34	Y37A1B.5	Y37A1B.5	n/a	chrIV 14,053,897	contains similarity to Pfam domain PF05694 56kDa selenium binding protein (SBP56) contains similarity to Interpro domains IPR008826 (Selenium-binding protein), IPR015943 (WD40/YVTN repeat-like)
35	F11A10.2	F11A10.2	n/a	chrIV 12,084,859	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR000690 (Zinc finger, C2H2-type matrin)
36	F47G9.3	F47G9.3	n/a	chrV 11,315,117	contains similarity to Pfam domains PF00100 (Zona pellucida-like domain) , PF00024 (PAN domain) (2)contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR001507 (Endoglin/CD105 antigen)
37	F55G1.15	F55G1.15	n/a	chrIV 7,499,036
38	gst-7	F11G11.2	n/a	chrII 4,882,703	gst-7 encodes a predicted glutathione S-transferase.
39	T06E6.1	T06E6.1	n/a	chrV 15,394,012	contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
40	R04E5.2	R04E5.2	n/a	chrX 8,814,421	R04E5.2 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2, C52D10.12, M02F4.3, and R13G10.4; by orthology with MAM3, R04E5.2 may participate in metal homoeostasis; R04E5.2, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; R04E5.2 has no obvious function in RNAi assays.
41	F40D4.13	F40D4.13	n/a	chrV 17,156,612	contains similarity to Homo sapiens Splice isoform 1 of P45378 Troponin T, fast skeletal muscle isoforms; SW:P45378
42	C01A2.3	C01A2.3	n/a	chrI 13,389,622	contains similarity to Pfam domain PF02096 60Kd inner membrane protein contains similarity to Interpro domain IPR001708 (60 kDa inner membrane insertion protein)
43	gst-14	F37B1.3	n/a	chrII 13,615,382	C. elegans GST-14 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
44	D1054.1	D1054.1	n/a	chrV 10,769,166	contains similarity to Pfam domain PF01734 Patatin-like phospholipase contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin)
45	R07E5.4	R07E5.4	n/a	chrIII 4,395,532	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
46	amx-3	F25C8.2	n/a	chrV 20,896,026	C. elegans AMX-3 protein; contains similarity to Pfam domain PF01593 Flavin containing amine oxidoreductase contains similarity to Interpro domains IPR000759 (Adrenodoxin reductase), IPR001613 (Flavin-containing amine oxidase), IPR002937 (Amine oxidase), IPR016040 (NAD(P)-binding)
47	his-7	F45F2.4	n/a	chrV 8,533,548	his-7 encodes an H2A histone.
48	C23H4.3	C23H4.3	n/a	chrX 12,227,955	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
49	F25G6.8	F25G6.8	n/a	chrV 8,564,846	contains similarity to Pfam domain PF02290 Signal recognition particle 14kD protein contains similarity to Interpro domains IPR009018 (Signal recognition particle, SRP9/SRP14 subunit), IPR003210 (Signal recognition particle, SRP14 subunit)
50	cln-3.1	F07B10.1	n/a	chrV 11,264,600	cln-3.1 encodes a predicted transmembrane protein that comprises one of three C. elegans homologs of human CLN3, (OMIM:607042, mutations are associated with Batten disease (also known as juvenile neuronal ceroid lipofuscinosis), a recessively inherited childhood neurodegenerative lysosomal storage disease); as loss of cln-3.1 activity via deletion mutation results in no obvious abnormalities, the precise role of cln-3.1 in C. elegans development and/or behavior is not yet known.