UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	adt-1	C02B4.1	0	chrX 12,683,974	The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis.
2	M05B5.6	M05B5.6	n/a	chrI 7,184,379	contains similarity to Homo sapiens Transient receptor potential cation channel subfamily A member 1; ENSEMBL:ENSP00000262209
3	F47F2.3	F47F2.3	n/a	chrX 3,894,817	contains similarity to Interpro domain IPR013032 (EGF-like region, conserved site)
4	F40G9.8	F40G9.8	n/a	chrIII 164,235
5	Y38H6C.9	Y38H6C.9	n/a	chrV 20,516,299	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
6	F45F2.6	F45F2.6	n/a	chrV 8,527,305	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
7	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	F11G11.4	F11G11.4	n/a	chrII 4,861,326
9	srx-136	F09F3.12	n/a	chrV 13,858,174	C. elegans SRX-136 protein ;
10	B0546.5	B0546.5	n/a	chrIV 3,389,078	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domain IPR010601 (Protein of unknown function DUF1182)
11	F45E6.3	F45E6.3	n/a	chrX 12,488,021	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
12	F35E2.1	F35E2.1	n/a	chrI 11,739,734	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR010601 (Protein of unknown function DUF1182)
13	C10E2.2	C10E2.2	n/a	chrX 16,746,897	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
14	F59C6.8	F59C6.8	n/a	chrI 10,511,155	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
15	T05B9.2	T05B9.2	n/a	chrII 11,257,607	contains similarity to Rattus norvegicus Fibrillin-2.; TR:Q9WUH9
16	C34D10.1	C34D10.1	n/a	chrX 8,030,420	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
17	F15A8.1	F15A8.1	n/a	chrX 4,441,526
18	F53B1.3	F53B1.3	n/a	chrX 2,106,394
19	C15B12.3	C15B12.3	n/a	chrX 6,467,380
20	T20D4.16	T20D4.16	n/a	chrV 3,394,536
21	str-115	F07B10.3	n/a	chrV 11,269,735	C. elegans STR-115 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	clec-243	Y68A4B.1	n/a	chrV 17,248,138	C. elegans CLEC-243 protein; contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)
23	sri-20	AC3.1	n/a	chrV 10,369,184	C. elegans SRI-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	C38H2.2	C38H2.2	n/a	chrIII 10,383,431	C38H2.2 encodes a core 1 UDP-Gal:GalNAcalpha1-Ser/Thr beta1,3-galactosyltransferase (core 1 beta3-Gal-T or T-synthase, EC2.4.1.122); C38H2.2 protein is predicted to be primarily extracellular, with an N-terminal transmembrane domain; C38H2.2 shares 6 conserved cysteine residues with all known T-synthases, and is ubiquitously expressed; enzymatically active C38H2.2 can be generated from insect but not mammalian cells, suggesting that invertebrate-specific chaperones are required for its activity.
25	F54G2.2	F54G2.2	n/a	chrX 2,636,226	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001878 (Zinc finger, CCHC-type)
26	Y106G6H.4	Y106G6H.4	n/a	chrI 10,437,301	contains similarity to Interpro domain IPR006578 (MADF)
27	mab-5	C08C3.3	n/a	chrIII 7,780,108	mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog.
28	F32B4.5	F32B4.5	n/a	chrI 11,519,244	contains similarity to Homo sapiens BTB/POZ domain-containing protein KCTD16; ENSEMBL:ENSP00000329906
29	T20D4.5	T20D4.5	n/a	chrV 3,414,578	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
30	rgs-1	C05B5.7	n/a	chrIII 10,015,270	rgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons.
31	srf-3	M02B1.1	n/a	chrIV 12,852,213	C. elegans SRF-3 protein; contains similarity to Pfam domains PF08449 (UAA transporter family) , PF04142 (Nucleotide-sugar transporter) contains similarity to Interpro domains IPR004689 (UDP-galactose transporter), IPR013657 (UAA transporter), IPR007271 (Nucleotide-sugar transporter)
32	F54D12.8	F54D12.8	n/a	chrII 1,396,527	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR003609 (Apple-like)
33	eat-4	ZK512.6	n/a	chrIII 9,139,280	eat-4 encodes an ortholog of the mammalian BNPI vesicular glutamate transporter that affects chemotaxis, feeding, foraging and thermotaxis; eat-4 is expressed in specific neurons, including M3L and M3R which are known to be glutamatergic.
34	npr-3	C10C6.2	n/a	chrIV 11,461,555	C10C6.2 encodes a G-protein-coupled receptor for the FMRFamide-related peptides (FaRPs) encoded by flp-15; C10C6.2 is primarily coupled to Gi/Go proteins, since C10C6.2 signalling is blocked by pertussis toxin; because of its link to Gi/Go proteins, C10C6.2 is expected to be inhibitory
35	sri-13	M01G12.13	n/a	chrI 12,141,648	C. elegans SRI-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	C49C3.15	C49C3.15	n/a	chrIV 17,334,573	contains similarity to Interpro domain IPR002101 (Myristoylated alanine-rich C-kinase substrate MARCKS)
37	T22D1.2	T22D1.2	n/a	chrIV 6,922,337	contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000694 (Proline-rich region), IPR000480 (Glutelin), IPR013286 (Annexin, type VII)
38	lgc-37	ZC482.5	n/a	chrIII 12,789,021	ZC482.5 is orthologous to the human gene GAMMA-AMINOBUTYRIC ACID A RECEPTOR GAMMA 2 (GABRG2; OMIM:137164), which when mutated leads to disease.
39	F23C8.3	F23C8.3	n/a	chrI 2,440,875
40	aqp-6	C32C4.2	n/a	chrV 10,651,251	apq-6 encodes an aquaporin whose expression in Xenopus oocytes increases water permeability five- to seven-fold; aqp-6 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-5; AQP-6 is expressed in the cilia and cell bodies of IL1 sensory neurons; AQP-6 is orthologous to human AQP8 (OMIM:603750).
41	C01G5.4	C01G5.4	n/a	chrIV 6,533,692	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR003125 (Protein of unknown function WSN), IPR001399 (VP6 blue-tongue virus inner capsid protein)
42	ZK896.1	ZK896.1	n/a	chrIV 12,874,056	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
43	C31E10.4	C31E10.4	n/a	chrX 13,989,751
44	F47B10.4	F47B10.4	n/a	chrX 10,891,428	contains similarity to Cyanophage P60 Thioredoxin C3.; TR:Q8W710
45	gpa-10	C55H1.2	n/a	chrV 6,853,746	gpa-10 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASI, ASJ, ALN, CAN, LUA, and the spermatheca.
46	str-253	F41B5.8	n/a	chrV 2,253,703	C. elegans STR-253 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
47	che-12	B0024.8	n/a	chrV 10,303,399	che-12 encodes a conserved protein that contains at least seven predicted HEAT repeats; CHE-12 activity is required continuously in sensory neurons for formation of distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis to a subset of attractants, including sodium chloride; a che-12::gfp promoter fusion is expressed in the two phasmid neurons and the subset of amphid neurons that contain relatively simple cilia; a CHE-12::GFP protein localizes to cilia in a manner suggesting that it requires intraflagellar transport for proper localization, but is unlikely to be a core IFT particle component; che-12 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor.
48	T05C1.1	T05C1.1	n/a	chrII 4,479,688
49	T21B6.4	T21B6.4	n/a	chrX 10,934,829	contains similarity to Interpro domain IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site)
50	F37C12.1	F37C12.1	n/a	chrIII 7,186,028	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)