UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C01H6.6	C01H6.6	0	chrI 7,223,298	C01H6.6 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C33D12.2, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C01H6.6 may participate in metal homoeostasis; C01H6.6, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C01H6.6 has no obvious function in RNAi assays.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	str-96	T10H4.2	n/a	chrV 15,293,203	C. elegans STR-96 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
4	pat-10	F54C1.7	n/a	chrI 5,019,533	pat-10 encodes body wall muscle troponin C, the calcium-binding component of the troponin complex of actin thin filaments; PAT-10 is essential for muscle contraction and thus for completion of embryonic morphogenesis and elongation; by homology, PAT-10 likely functions to regulate body wall muscle contraction in response to changes in intracellular calcium; PAT-10 is expressed in body wall muscle but is also detected in vulval and anal muscles; expression in body wall muscle begins during early embryonic morphogenesis, concurrent with expression of other body wall muscle structural components.
5	dhs-30	T25G12.7	n/a	chrX 17,233,193	dhs-30 encodes a member of the short-chain dehydrogenases/reductases family (SDR) homologous to HSD, which when mutated leads to cortisol 11-beta ketoreductase deficiency (OMIM:218030).
6	lgc-12	R13A5.4	n/a	chrIII 7,563,273	C. elegans LGC-12 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
7	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
8	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
9	K06H6.2	K06H6.2	n/a	chrV 586,550	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
10	C50C3.2	C50C3.2	n/a	chrIII 8,185,577	contains similarity to Pfam domains PF00435 (Spectrin repeat) (4), PF00036 (EF hand) contains similarity to Interpro domains IPR002017 (Spectrin repeat), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
11	C14A4.13	C14A4.13	n/a	chrII 10,619,389	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
12	W07B8.3	W07B8.3	n/a	chrV 1,125,705
13	srh-115	Y61B8A.2	n/a	chrV 17,256,442	C. elegans SRH-115 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	K07H8.7	K07H8.7	n/a	chrIV 8,259,664	contains similarity to Interpro domain IPR000079 (High mobility group protein HMG14 and HMG17)
15	C50F7.9	C50F7.9	n/a	chrIV 7,731,347
16	F31E9.3	F31E9.3	n/a	chrV 17,323,648	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
17	hmit-1.2	Y51A2D.5	n/a	chrV 18,526,923	hmit-1.2 encodes one of three C. elegans proton (H+)-dependent myo-inositol transporters; loss of hmit-1.2 activity via large-scale RNAi result in no obvious abnormalities but by homology, HMIT-1.2 is predicted to function as a plasma membrane protein required for the regulated uptake of myo-inositol and thus potentially for regulation of cell signaling and intracellular osmolarity.
18	srh-105	T27A1.7	n/a	chrII 508,784	C. elegans SRH-105 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	C08E8.2	C08E8.2	n/a	chrV 18,354,641	contains similarity to Pfam domain PF03088 Strictosidine synthase contains similarity to Interpro domains IPR004141 (Strictosidine synthase), IPR011042 (Six-bladed beta-propeller, TolB-like)
20	T12B3.4	T12B3.4	n/a	chrIV 7,386,993	contains similarity to Pfam domain PF03637 Mob1/phocein family contains similarity to Interpro domain IPR005301 (Mob1/phocein)
21	F33C8.4	F33C8.4	n/a	chrX 14,733,294	contains similarity to Interpro domain IPR006209 (EGF-like domain)
22	F59A6.4	F59A6.4	n/a	chrII 5,006,559	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
23	Y43F8A.3	Y43F8A.3	n/a	chrV 19,379,196	contains similarity to Pfam domain PF07859 alpha/beta hydrolase fold contains similarity to Interpro domains IPR017157 (Arylacetamide deacetylase), IPR013094 (Alpha/beta hydrolase fold-3)
24	C24A11.2	C24A11.2	n/a	chrI 5,381,597
25	ets-5	C42D8.4	n/a	chrX 5,080,670	C. elegans ETS-5 protein; contains similarity to Pfam domain PF00178 Ets-domain contains similarity to Interpro domains IPR000418 (Ets), IPR011991 (Winged helix repressor DNA-binding)
26	Y39A1A.18	Y39A1A.18	n/a	chrIII 10,692,438	contains similarity to Methanosarcina mazei Transcriptional regulator, MerR family.; TR:Q8PSB2
27	F57G4.9	F57G4.9	n/a	chrV 17,644,291	contains similarity to Xenopus laevis Putative uncharacterized protein.; TR:Q08AY0
28	C34G6.1	C34G6.1	n/a	chrI 5,912,249	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
29	R07H5.10	R07H5.10	n/a	chrIV 11,214,469	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
30	grd-8	C37C3.4	n/a	chrV 7,843,402	grd-8 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-8 is expressed in larval intestine and neurons; the grd-8 gene is directly bound by DAF-12 and requires DAF-12 for full transcription; GRD-8's Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-8 is weakly required for normal molting; GRD-8 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
31	D1007.3	D1007.3	n/a	chrI 4,576,495
32	ubc-23	C28G1.1	n/a	chrX 8,846,276	ubc-23 encodes a predicted conjugating enzyme (UBCs/E2s) of the ubiquitin-conjugation system; expressed in larvae and adults in cells around the pharynx and in intestinal cells.
33	C08H9.13	C08H9.13	n/a	chrII 9,870,236	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR003624 (Leukemia inhibitory factor), IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
34	lips-13	T13B5.7	n/a	chrII 1,116,848	C. elegans LIPS-13 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
35	C25F9.5	C25F9.5	n/a	chrV 19,409,124	contains similarity to Pfam domain PF00176 SNF2 family N-terminal domain contains similarity to Interpro domain IPR000330 (SNF2-related)
36	K03H1.5	K03H1.5	n/a	chrIII 9,935,960	contains similarity to Pfam domains PF03782 (AMOP domain) , PF06119 (Nidogen-like) , PF00094 (von Willebrand factor type D domain) , PF00084 (Sushi domain (SCR repeat)) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR005533 (AMOP), IPR002909 (Cell surface receptor IPT/TIG), IPR000436 (Sushi/SCR/CCP), IPR000694 (Proline-rich region), IPR003886 (Nidogen, extracellular region), IPR016060 (Complement control module), IPR001846 (von Willebrand factor, type D)
37	twk-1	F21C3.1	n/a	chrI 7,270,700	C. elegans TWK-1 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
38	R06F6.6	R06F6.6	n/a	chrII 10,807,531	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR013847 (POU), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
39	frm-9	F31B12.3	n/a	chrX 10,817,663	frm-9 encodes a B41/ERM (ezrin/radixin/moesin) domain containing protein.
40	F10D11.4	F10D11.4	n/a	chrI 8,441,960	contains similarity to Interpro domain IPR005819 (Histone H5)
41	F37C4.2	F37C4.2	n/a	chrIV 3,887,244	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
42	lite-1	C14F11.3	n/a	chrX 6,228,375	C. elegans LITE-1 protein; contains similarity to Pfam domain PF08395 7tm Chemosensory receptor contains similarity to Interpro domains IPR009318 (Trehalose receptor), IPR013604 (7TM chemoreceptor)
43	C27C7.5	C27C7.5	n/a	chrI 11,425,014	contains similarity to Pfam domains PF00337 (Galactoside-binding lectin) , PF08277 (PAN-like domain) contains similarity to Interpro domains IPR006583 (CW), IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
44	F57G4.5	F57G4.5	n/a	chrV 17,642,359	contains similarity to Mus musculus Dentin sialophosphoprotein precursor (Dentin matrix protein-3) (DMP-s3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP);sDentin sialoprotein (DSP)].; SW:DSPP_MOUSE
45	C55A6.7	C55A6.7	n/a	chrV 11,519,888	contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
46	ZK402.2	ZK402.2	n/a	chrX 1,403,926	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
47	K02B2.3	K02B2.3	n/a	chrIV 5,938,425	contains similarity to Pfam domain PF04678 Protein of unknown function, DUF607 contains similarity to Interpro domain IPR006769 (Protein of unknown function DUF607)
48	fbxa-111	Y102A5C.14	n/a	chrV 16,949,135	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
49	cpb-1	C40H1.1	n/a	chrIII 9,323,513	cpb-1 encodes a cytoplasmic polyadenylation element binding (CPEB) protein homolog involved in two steps of spermatogenesis; two CPEB proteins have distinct functions in spermatogenesis, with FOG-1 specifying sperm cell fate, and CPB-1 conversely executing that decision, being required for progression through meiosis; cpb-1(RNAi) spermatocytes fail to undergo meiotic cell divisions; CPB-1 protein is present in the germ line just prior to overt spermatogenesis, but once sperm differentiation begins, CPB-1 disappears; CPB-1 physically interacts with EBF, which, like CPEB, regulates genes by binding the 3' UTRs of mRNAs; while CPB-1 is required for spermatogenesis, it is dispensable for oogenesis; this is in contrast to CPEBs in vertebrates (Xenopus), arthropods (Drosophila), and molluscs (Spisula), which all participate in oogenesis.
50	sru-35	C33D9.4	n/a	chrIV 8,789,328	C. elegans SRU-35 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)