UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	dhs-1	C01G8.3	0	chrI 5,280,165	C. elegans DHS-1 protein; contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
2	C16A11.5	C16A11.5	n/a	chrII 4,224,777	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
3	C53B7.7	C53B7.7	n/a	chrX 6,862,206	C53B7.7 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C53B7.7 has no clear orthologs in other organisms.
4	dod-18	C54G4.6	n/a	chrI 8,020,275	dod-18 encodes a Maf-like protein required for normally short lifespan; dod-18 is repressed in daf-2 mutants and induced in daf-16 mutants, and dod-18(RNAi) lengthens lifespan by 30%; MAF-like proteins are ubiquitous among eukarya, bacteria, and archaea; DOD-18 is orthologous to the N-terminal ~200 residues of human ASMTL (OMIM:300162), and to Bacillus subtilis Maf (Multicopy Associated Filamentation) protein, which inhibits septum formation; while the specific biochemical function of Maf-like proteins is unknown, the tertiary structure of B. subtilis Maf is consistent with its binding nucleic acid.
5	F46F11.8	F46F11.8	n/a	chrI 5,625,448
6	C06A8.2	C06A8.2	n/a	chrII 7,780,233	contains similarity to Homo sapiens snRNA-activating protein complex subunit 1; ENSEMBL:ENSP00000216294
7	bath-3	F59H6.10	n/a	chrII 2,029,895	C. elegans BATH-3 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
8	T05E7.3	T05E7.3	n/a	chrI 6,190,389	contains similarity to Interpro domain IPR000463 (Cytosolic fatty-acid binding)
9	ZC302.3	ZC302.3	n/a	chrV 10,739,944	contains similarity to Adoxophyes honmai nucleopolyhedrovirus Hypothetical protein.; TR:Q80LN9
10	H14A12.3	H14A12.3	n/a	chrIII 7,464,450	H14A12.3 encodes an ortholog of S. cerevisiae RAV2; like RAV2, H14A12.3 may be required for the reassociation of vacuolar proton-translocating ATPase (V-ATPase) after temporary glucose starvation.
11	bath-7	F52C6.10	n/a	chrII 1,920,562	C. elegans BATH-7 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
12	F13G3.6	F13G3.6	n/a	chrI 7,304,082	contains similarity to Pfam domain PF00535 Glycosyl transferase family 2 contains similarity to Interpro domains IPR001173 (Glycosyl transferase, family 2), IPR016040 (NAD(P)-binding)
13	sid-1	C04F5.1	n/a	chrV 5,123,427	The sid-1 gene encodes a predicted transmembrane protein with conserved human (OMIM:606816) and mouse homologs of unknown function and is required cell autonomously for systemic RNA interference (RNAi); a SID-1::GFP fusion is enriched at the cell periphery of most nonneuronal cells from late embryogenesis through adulthood with highest levels detected in cells exposed to the environment.
14	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
15	fkh-6	B0286.5	n/a	chrII 4,381,579	fkh-6 encodes one of 15 C. elegans forkhead transcription factors; fkh-6 is required for several aspects of male gonadogenesis including asymmetric cell division, cell migration and sex determination and appears to act downstream of tra-1; FKH-6 is specifically expressed in the gonad.
16	F55B11.3	F55B11.3	n/a	chrIV 14,425,099	contains similarity to Lactococcus lactis Unknown protein.; TR:Q9CF31
17	F57C9.7	F57C9.7	n/a	chrI 4,825,902
18	T02C12.2	T02C12.2	n/a	chrIII 4,020,894	contains similarity to Danio rerio Zgc:56295.; TR:Q7ZU76
19	C48E7.2	C48E7.2	n/a	chrI 6,256,337	contains similarity to Pfam domains PF08221 (RNA polymerase III subunit RPC82 helix-turn-helix domain) , PF05645 (RNA polymerase III subunit RPC82) contains similarity to Interpro domains IPR013197 (RNA polymerase III subunit RPC82-related, helix-turn-helix), IPR008806 (RNA polymerase III Rpc82, C -terminal)
20	T02E1.2	T02E1.2	n/a	chrI 8,221,514	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IJZ2
21	M02B7.2	M02B7.2	n/a	chrIV 3,804,264	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
22	F48E8.2	F48E8.2	n/a	chrIII 5,466,142	contains similarity to Mus musculus E2F-associated phosphoprotein (EAPP).; SW:Q5BU09
23	Y116A8C.8	Y116A8C.8	n/a	chrIV 16,932,518	contains similarity to Interpro domain IPR001283 (Allergen V5/Tpx-1 related)
24	C01G10.7	C01G10.7	n/a	chrV 15,086,381	contains similarity to Pfam domain PF03328 HpcH/HpaI aldolase/citrate lyase family contains similarity to Interpro domains IPR011206 (Citrate lyase, beta subunit), IPR005000 (HpcH/HpaI aldolase), IPR015813 (Pyruvate/Phosphoenolpyruvate kinase, catalytic core)
25	rnf-5	C16C10.7	n/a	chrIII 4,165,557	This gene encodes a homolog of mammalian RNF5, a C3HC4 (RING-finger) zinc-finger protein.
26	R11A8.2	R11A8.2	n/a	chrIV 10,359,115	contains similarity to Interpro domains IPR008991 (Translation protein SH3-like), IPR005824 (KOW), IPR000467 (D111/G-patch)
27	M03C11.2	M03C11.2	n/a	chrIII 10,402,129	contains similarity to Pfam domain PF06733 DEAD_2 contains similarity to Interpro domains IPR014013 (Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type), IPR010614 (DEAD2), IPR006554 (Helicase-like, DEXD box c2 type), IPR006555 (Helicase, ATP-dependent, c2 type), IPR014001 (DEAD-like helicase, N-terminal), IPR013020 (DNA helicase (DNA repair), Rad3 type)
28	efn-3	F15A2.5	n/a	chrX 13,476,463	efn-3 encodes a potential GPI-modified ephrin that is, with EFN-2, is required for normal epidermal organization in the male tail; EFN-3, along with EFN-1 and EFN-2, activates the VAB-1 tyrosine kinase in vivo and binds it in vitro, and has a minor role in embryonic epiboly.
29	K04G2.2	K04G2.2	n/a	chrI 8,031,912	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q17GK3
30	R07E5.1	R07E5.1	n/a	chrIII 4,410,321	contains similarity to Pfam domains PF07713 (Protein of unknown function (DUF1604)) , PF01585 (G-patch domain) contains similarity to Interpro domains IPR011666 (Protein of unknown function DUF1604), IPR000467 (D111/G-patch), IPR005398 (Tubby, N-terminal)
31	M05D6.2	M05D6.2	n/a	chrII 8,469,058	contains similarity to Pfam domain PF05794 T-complex protein 11 contains similarity to Interpro domain IPR008862 (T-complex 11)
32	D1086.4	D1086.4	n/a	chrV 14,091,601	contains similarity to Saccharomyces cerevisiae GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2; SGD:YAL035W
33	fbxa-108	F59A1.7	n/a	chrV 17,657,524	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
34	srh-141	T08G3.5	n/a	chrV 16,444,803	C. elegans SRH-141 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	ZK742.2	ZK742.2	n/a	chrV 7,802,661	contains similarity to Homo sapiens Isoform 1 of Uncharacterized protein KIAA1530; ENSEMBL:ENSP00000374501
36	W05H7.2	W05H7.2	n/a	chrX 1,435,503
37	C16C10.1	C16C10.1	n/a	chrIII 4,180,220	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
38	F54D11.3	F54D11.3	n/a	chrV 4,636,257
39	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
40	dhs-22	C15H11.4	5e-23	chrV 14,420,734	dhs-22 encodes a short-chain dehydrogenase predicted to be mitochondrial.
41	spd-3	H34C03.1	n/a	chrIV 6,763,933	C. elegans SPD-3 protein ;
42	nlp-23	T24D8.4	n/a	chrX 2,342,692	nlp-23 encodes three predicted neuropeptide-like proteins; in C. elegans, nlp-23 is part of the FRPamide neuropeptide family that also contains nlp-2 and nlp-22; nlp-23 is expressed in the tail and in dorsal and ventral hypodermis; as loss of nlp-23 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of the nlp-23-encoded peptides in development and/or behavior is not yet known.
43	uev-1	F39B2.2	n/a	chrI 14,790,521	uev-1 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the characteristic UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-1 in C. elegans development and/or behavior is not yet known; UEV-1 does, however, interact with a number of proteins, such as UBC-13, that are likely involved in the response to DNA damage; thus, UEV-1 may play a role in ubiquitination and protein turnover in conjunction with DNA repair or the DNA damage checkpoint pathway.
44	M01G5.1	M01G5.1	n/a	chrIII 1,503,267	contains similarity to Homo sapiens hypothetical protein; VG:OTTHUMP00000024537
45	K08D9.5	K08D9.5	n/a	chrV 3,225,335	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
46	W06E11.1	W06E11.1	n/a	chrIII 643,797	contains similarity to Pfam domain PF04801 Sin-like protein conserved region contains similarity to Interpro domain IPR006886 (Sin-like protein conserved region)
47	C06G3.8	C06G3.8	n/a	chrIV 7,032,043	contains similarity to Pfam domain PF01336 OB-fold nucleic acid binding domain contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold)
48	C56C10.9	C56C10.9	n/a	chrII 6,591,647	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
49	bath-4	F52C6.8	n/a	chrII 1,917,377	C. elegans BATH-4 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
50	edc-3	R05D11.8	n/a	chrI 8,603,637	C. elegans EDC-3 protein; contains similarity to Interpro domain IPR010920 (Like-Sm ribonucleoprotein-related, core)