UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C01B4.8	C01B4.8	0	chrV 2,491,606	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	R102.1	R102.1	n/a	chrIV 10,686,816	contains similarity to Oryza sativa Similar to Arabidopsis thaliana chromosome 4.; TR:Q9LWR6
4	F41C6.6	F41C6.6	n/a	chrX 6,881,383
5	M7.12	M7.12	n/a	chrIV 11,097,281	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
6	cyp-33C8	R08F11.3	n/a	chrV 3,802,105	C. elegans CYP-33C8 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
7	pqn-60	R11G11.7	n/a	chrV 504,306	pqn-60 encodes a 154-residue, glutamine/asparagine (Q/N)-rich ('prion'-like) protein, predicted to have coiled-coil structure, with many paralogs in nematodes but no obvious non-nematode orthologs; PQN-60 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51.
8	arf-1.1	F45E4.1	n/a	chrIV 7,635,253	arf-1.1 encodes a member of the ADP-ribosylation factor family.
9	K01A6.4	K01A6.4	n/a	chrIV 11,739,659	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001419 (HMW glutenin)
10	daf-5	W01G7.1	n/a	chrII 14,035,373	daf-5 encodes a proline-rich protein, conserved in C. briggsae but not observed in non-nematode genomes, that promotes dauer formation in the group II branch of the dauer pathway, may regulate chemosensation via AWC neurons, and may regulate egg laying; daf-5 mutations suppress the dauer phenotype of group II Daf-c mutants; daf-5(e1385) partially suppresses dauer formation by aex-6(sa699) mutants at 26.8 degrees C.
11	B0238.12	B0238.12	n/a	chrV 5,268,306	B0238.12 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; B0238.12 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; B0238.12 has no obvious function in mass RNAi assays.
12	F37H8.3	F37H8.3	n/a	chrII 11,182,323	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR011945 (Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal), IPR006402 (HAD-superfamily hydrolase, subfamily IA, variant 3), IPR005834 (Haloacid dehalogenase-like hydrolase)
13	F56D2.8	F56D2.8	n/a	chrIII 5,581,951
14	ins-26	ZC334.1	n/a	chrI 14,037,463	ins-26 encodes an insulin-like peptide.
15	F28B1.1	F28B1.1	n/a	chrV 17,043,156	contains similarity to Mus musculus Hypothetical protein.; TR:Q8C3I4
16	C46H11.6	C46H11.6	n/a	chrI 5,022,021	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
17	M04G7.1	M04G7.1	n/a	chrIV 456,400	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR000877 (Proteinase inhibitor I12, Bowman-Birk), IPR003582 (Metridin-like ShK toxin)
18	K08D9.4	K08D9.4	n/a	chrV 3,199,601	contains similarity to Pfam domain PF06342 Alpha/beta hydrolase of unknown function (DUF1057) contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR010463 (Protein of unknown function DUF1057, lipase putative), IPR003089 (Alpha/beta hydrolase)
19	ugt-43	F01D4.1	n/a	chrIV 10,466,113	C. elegans UGT-43 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
20	ZK849.1	ZK849.1	n/a	chrI 14,184,199	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
21	R05H10.1	R05H10.1	n/a	chrII 14,852,898	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
22	ZK1010.5	ZK1010.5	n/a	chrIII 12,985,882	contains similarity to Interpro domain IPR000694 (Proline-rich region)
23	mab-9	T27A1.6	n/a	chrII 518,813	mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 affects movement to some extent though the basis for this defect is unknown; MAB-9 localizes to the nucleus of B and F and their descendents during development.
24	myo-2	T18D3.4	n/a	chrX 12,471,624	myo-2 encodes a muscle-type specific myosin heavy chain isoform; myo-2 is expressed in pharyngeal muscle.
25	D1005.3	D1005.3	n/a	chrX 1,453,357	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
26	E02C12.11	E02C12.11	n/a	chrV 9,379,644	contains similarity to Pfam domain PF07914 Protein of unknown function (DUF1679) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species)
27	scrm-6	F46A8.10	n/a	chrI 11,254,608	scrm-6 encodes a putative phospholipid scramblase homologous to human PLSCR1-5, and paralogous to other C. elegans SCRMs (e.g., SCRM-1); scrm-6(RNAi) animals have no obvious phenotype.
28	Y23H5A.4	Y23H5A.4	n/a	chrI 2,618,955	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
29	Y48A6B.8	Y48A6B.8	n/a	chrIII 11,028,225	contains similarity to Interpro domains IPR003547 (Serine/threonine protein kinase, yersinia), IPR013022 (Xylose isomerase-like, TIM barrel)
30	Y43F8C.15	Y43F8C.15	n/a	chrV 19,705,582
31	C49G7.10	C49G7.10	n/a	chrV 4,041,191	contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
32	F58F9.6	F58F9.6	n/a	chrIV 6,236,744	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
33	C01G10.5	C01G10.5	n/a	chrV 15,089,276	contains similarity to Homo sapiens Glycine/tyrosine-rich protein; ENSEMBL:ENSP00000335001
34	C01B12.4	C01B12.4	n/a	chrII 7,948	contains similarity to Interpro domain IPR005178 (Protein of unknown function DUF300)
35	clec-135	C16A11.8	n/a	chrII 4,257,930	C. elegans CLEC-135 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
36	F35H12.1	F35H12.1	n/a	chrX 936,580	contains similarity to Interpro domain IPR015649 (Schwannomin interacting protein 1)
37	ncl-1	ZK112.2	n/a	chrIII 7,734,657	ncl-1 encodes a cytoplasmic B-box zinc finger protein that negatively regulates rRNA and 5S RNA transcription, nucleolus size, and body size; NCL-1 is orthologous to Drosophila BRAIN TUMOR (BRAT), and ncl-1 mutants can be rescued by brat transgenes; NCL-1 is required for the normally small size of neuronal, muscle, and hypodermal nucleoli, and is already active in 4-cell embryos; NCL-1 may be a repressor of RNA polymerase I and III transcription and an inhibitor of cell growth, based on mutant analysis; ncl-1 animals have much larger neuronal nucleoli than normal, somewhat larger muscle and hypodermal nucleoli, but essentially normal intestinal and germline nucleoli (the last of which are large even in wild-type animals); conversely, intestinal and germline cells have the lowest amounts of NCL-1 protein; ncl-1 animals are 9% larger, have 22% more protein and twice as much rRNA, and transcribe rRNA twice as much as wild-type worms; ncl-1 functions cell autonomously, and ncl-1 mutations suppress the tumorous germline phenotype of pro-1(na48) mutants.
38	C18H7.7	C18H7.7	n/a	chrIV 596,081
39	clec-99	ZK39.8	n/a	chrI 11,157,780	C. elegans CLEC-99 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
40	R148.7	R148.7	n/a	chrIII 3,196,950
41	tbb-6	T04H1.9	n/a	chrV 12,262,563	C. elegans TBB-6 protein; contains similarity to Pfam domains PF00091 (Tubulin/FtsZ family, GTPase domain) , PF03953 (Tubulin/FtsZ family, C-terminal domain) contains similarity to Interpro domains IPR002454 (Gamma tubulin), IPR002452 (Alpha tubulin), IPR002453 (Beta tubulin), IPR000217 (Tubulin), IPR003008 (Tubulin/FtsZ, GTPase), IPR004057 (Epsilon tubulin), IPR002967 (Delta tubulin), IPR008280 (Tubulin/FtsZ, C-terminal)
42	F35C5.1	F35C5.1	n/a	chrII 12,881,287	contains similarity to Saccharomyces cerevisiae B-type regulatory subunit of protein phosphatase 2A (PP2A); SGD:YOR014W
43	K07F5.8	K07F5.8	n/a	chrIV 9,849,087	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
44	scl-25	T19C9.5	n/a	chrV 17,227,538	C. elegans SCL-25 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
45	gst-40	F56B3.10	n/a	chrIV 761,476	C. elegans GST-40 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
46	gcy-12	F08B1.2	n/a	chrII 5,314,665	gcy-12 encodes a membrane guanylyl cyclase; a gcy-12::GFP reporter is expressed in the PHA neurons as well as in a number of head sensory neurons including AFD, AWC, and ASE; when expressed in COS-M6 cells, GCY-12 exhibits temperature-dependent guanylyl cyclase activity.
47	AC7.3	AC7.3	n/a	chrIV 5,112,248
48	gpa-2	F38E1.5	n/a	chrV 8,372,499	gpa-2 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that is involved in dauer formation and chemotaxis to water-soluble odorants; it is expressed in the phasmid neurons PHA and PHB, three pharyngeal neurons, one interneuron, three pairs of head neurons, and the anal sphincter muscle.
49	T01H3.5	T01H3.5	n/a	chrII 7,880,026	T01H3.5 encodes an unfamiliar protein; T01H3.5 and T01H3.5 share an operon divergently transcribed from another operon containing vha-4.
50	Y116A8C.38	Y116A8C.38	n/a	chrIV 17,132,537	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)