UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C01B12.3	C01B12.3	0	chrII 14,491	C01B12.3 is orthologous to the human gene VITELLIFORM MACULAR DYSTROPHY PROTEIN (VMD2; OMIM:153700), which when mutated leads to disease.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F42H10.5	F42H10.5	n/a	chrIII 8,476,425	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domains IPR008906 (HAT dimerisation), IPR003656 (Zinc finger, BED-type predicted)
4	srw-136	K12D9.10	n/a	chrV 3,009,736	C. elegans SRW-136 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
5	drh-1	F15B10.2	n/a	chrIV 6,610,349	drh-1 encodes a DExH-box helicase; loss of drh-1 activity via RNAi suggests that drh-1 is required, perhaps redundantly with drh-2, for both germline and somatic RNA interference (RNAi); DRH-1 interacts in vivo with RDE-4, a double-stranded RNA-binding protein required for the initiation phase of RNAi.
6	C39D10.1	C39D10.1	n/a	chrX 7,906,986
7	F45D3.2	F45D3.2	n/a	chrV 12,541,972	contains similarity to Dictyocaulus viviparus Putative uncharacterized protein.; TR:Q6E6T3
8	sra-8	AH6.12	n/a	chrII 9,538,328	C. elegans SRA-8 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
9	F44D12.1	F44D12.1	n/a	chrIV 10,012,047	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domains IPR008144 (Guanylate kinase), IPR008145 (Guanylate kinase/L-type calcium channel region), IPR001452 (Src homology-3), IPR001478 (PDZ/DHR/GLGF)
10	tpst-2	F42G9.8	n/a	chrIII 772,135	C. elegans TPST-2 protein ; contains similarity to Drosophila melanogaster Flybase gene name is Tango13-PC;; FLYBASE:CG32632
11	C54G4.4	C54G4.4	n/a	chrI 7,999,947	contains similarity to Pfam domain PF00084 Sushi domain (SCR repeat) contains similarity to Interpro domains IPR002396 (Selectin (CD62E/L/P antigen)), IPR006585 (Fucolectin tachylectin-4 pentraxin-1), IPR000436 (Sushi/SCR/CCP), IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016060 (Complement control module), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
12	B0399.2	B0399.2	n/a	chrV 19,551,938	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
13	srd-45	F17A2.7	n/a	chrX 12,329,674	C. elegans SRD-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	Y16B4A.2	Y16B4A.2	n/a	chrX 14,766,829	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
15	T21E12.3	T21E12.3	n/a	chrI 4,403,989	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
16	nhr-255	ZK678.2	n/a	chrX 15,743,376	C. elegans NHR-255 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000679 (Zinc finger, GATA-type), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
17	gcy-3	R134.1	n/a	chrII 9,504,941	gcy-3 is predicted to encode a guanylate cyclase.
18	str-123	T22H6.4	n/a	chrX 12,790,964	C. elegans STR-123 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	srd-69	H04J21.2	n/a	chrIII 2,364,601	C. elegans SRD-69 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	sma-3	R13F6.9	n/a	chrIII 6,862,404	sma-3 encodes a Smad protein; during development, SMA-3 functions as part of a DBL-1/SMA-6 TGF-beta-related signaling pathway that controls body size and male tail sensory ray and spicule formation; sma-3 is widely expressed at all developmental stages, beginning during embryogenesis, continuing through all larval stages, and seen very strongly in adult hermaphrodites and males; a SMA-3::GFP is detected in the pharynx, intestine, and hypodermis and localizes to the nucleus; sma-3 expression in the hypodermis is necessary and sufficient for normal body size; SMA-3 can physically interact with the LIN-31 forkhead transcription factor.
21	F40A3.1	F40A3.1	n/a	chrV 7,893,499
22	srh-190	C17E7.2	n/a	chrV 3,903,811	C. elegans SRH-190 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	T02G6.3	T02G6.3	n/a	chrI 11,814,056	contains similarity to Homo sapiens Splice isoform 2 of Q86UP2 Kinectin; ENSEMBL:ENSP00000337744
24	C17B7.10	C17B7.10	n/a	chrV 3,341,460	C17B7.10 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C17B7.10 has no clear orthologs in other organisms.
25	F15D3.9	F15D3.9	n/a	chrI 11,558,305
26	F59D12.1	F59D12.1	n/a	chrX 15,669,484	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
27	gpa-13	F18E2.5	n/a	chrV 12,753,806	gpa-13 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASH, AWC, PHA, and PHB.
28	srg-36	K04C1.6	n/a	chrX 14,230,194	C. elegans SRG-36 protein; contains similarity to Interpro domains IPR000539 (Frizzled protein), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
29	str-254	F10A3.9	n/a	chrV 16,152,699	C. elegans STR-254 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	C32B5.14	C32B5.14	n/a	chrII 966,320
31	tag-123	F08F1.7	n/a	chrX 8,420,290	C. elegans TAG-123 protein; contains similarity to Pfam domain PF02990 Endomembrane protein 70 contains similarity to Interpro domains IPR008075 (Lipocalin-1 receptor), IPR004240 (Nonaspanin (TM9SF))
32	T23C6.5	T23C6.5	n/a	chrX 17,156,542	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR004827 (Basic-leucine zipper (bZIP) transcription factor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
33	srz-47	Y68A4A.2	n/a	chrV 17,191,554	C. elegans SRZ-47 protein ;
34	col-75	K03H9.2	n/a	chrII 6,426,809	C. elegans COL-75 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
35	nhr-241	Y69H2.8	n/a	chrV 18,700,186	C. elegans NHR-241 protein
36	clec-182	C33D9.2	n/a	chrIV 8,797,600	C. elegans CLEC-182 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
37	nhr-278	ZK6.1	n/a	chrV 409,173	C. elegans NHR-278 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000679 (Zinc finger, GATA-type), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
38	F35E8.9	F35E8.9	n/a	chrV 15,916,920	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
39	C46H11.1	C46H11.1	n/a	chrI 5,055,865
40	F52H2.1	F52H2.1	n/a	chrX 2,574,893
41	srh-207	ZK262.1	n/a	chrV 18,409,607	C. elegans SRH-207 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	unc-7	R07D5.1	n/a	chrX 15,134,407	unc-7 encodes an innexin required for gap junction formation in invertebrates; UNC-7 is also required for normal locomotion, egg-laying, inhibition of feeding by tapping, avermectin sensitivity, and ivermectin sensitivity, as well as for the antagonism of UNC-79 and UNC-80 activity by volatile anesthetics; unc-7 is genetically required, and transcribed in, neurons rather than muscle cells, from larval stages L1 through L4; homologs of UNC-7 include Drosophila OGRE and SHAKING-B, as well as 24 C. elegans paralogs (including EAT-5, UNC-9, and INX-1 through INX-20); UNC-7 genetically interacts with UNC-124, and unc-7 mutants are phenotypically similar to unc-9 and unc-124 mutants; UNC-7 genetically interacts with AVR-14 and GLC-1 in the response to ivermectin.
43	C34F6.10	C34F6.10	n/a	chrX 11,233,244	contains similarity to Pfam domain PF00041 Fibronectin type III domain contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR000694 (Proline-rich region)
44	T23F6.5	T23F6.5	n/a	chrIV 12,736,831	contains similarity to Escherichia coli O157:H7 Hypothetical protein ECs1561.; TR:Q8X5G5
45	srt-16	C50H11.11	n/a	chrV 3,064,037	C. elegans SRT-16 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
46	ceh-24	F55B12.1	n/a	chrV 13,814,273	ceh-24 is orthologous to the human gene SIMILAR TO THYROID TRANSCRIPTION FACTOR 1 (TITF1; OMIM:600635), which when mutated leads to disease.
47	str-16	Y73C8A.1	n/a	chrV 3,239,764	C. elegans STR-16 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
48	F59A3.1	F59A3.1	n/a	chrI 5,525,077	F59A3.1 encodes one of two C. elegans carboxypeptidase D homologs; loss of F59A3.1 activity via large-scale RNAi screens in a sensitized, rrf-3 mutant background results in larval lethality, abnormal locomotion, and abnormal morphogenesis of the vulval epithelium resulting in rupture; high-throughput expression studies report F59A3.1 expression in the pharynx only.
49	srj-44	T03D3.11	n/a	chrV 2,845,216	C. elegans SRJ-44 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	exc-9	F20D12.5	n/a	chrIV 7,940,302	exc-9 encodes a LIM domain-containing protein; exc-9 activity is required for proper development and morphogenesis of the excretory cell canal.