UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	tsp-11	B0563.2	6.000000000000001e-165	chrX 9,164,502	C. elegans TSP-11 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
2	B0495.6	B0495.6	n/a	chrII 7,698,778	contains similarity to Pfam domain PF07189 Splicing factor 3B subunit 10 (SF3b10) contains similarity to Interpro domain IPR009846 (Splicing factor 3B subunit 5/RDS3 complex subunit 10)
3	pmp-3	C54G10.3	n/a	chrV 14,650,313	pmp-3 encodes a putative ABC transporter orthologous to human ABCD4 (OMIM:603214) and paralogous to PMP-5; pmp-3 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults; PMP-3 has no obvious function in mass RNAi assays, and pmp-3(ok1087) mutants are at least grossly normal (in particular, they show no defects in the uptake stage of RNAi).
4	srt-5	C50H11.14	n/a	chrV 3,080,169	C. elegans SRT-5 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
5	F54E4.4	F54E4.4	n/a	chrX 14,643,359	contains similarity to Pfam domain PF03931 Skp1 family, tetramerisation domain contains similarity to Interpro domains IPR001232 (SKP1 component), IPR011333 (BTB/POZ fold), IPR016073 (SKP1 component, POZ)
6	W10G11.4	W10G11.4	n/a	chrII 3,563,054	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
7	K07D4.4	K07D4.4	n/a	chrII 4,032,008
8	tag-83	F46F11.3	n/a	chrI 5,602,718	C. elegans TAG-83 protein ; contains similarity to Homo sapiens TNS1 protein; ENSEMBL:ENSP00000308321
9	F25G6.1	F25G6.1	n/a	chrV 8,577,457
10	soc-1	F41F3.2	n/a	chrV 4,644,923	C. elegans SOC-1 protein; contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type)
11	R07A4.2	R07A4.2	n/a	chrX 10,745,349	contains similarity to Rhodopirellula baltica Probable serine/threonine-protein kinase pknB (EC 2.7.1.-).; TR:Q7UFE6
12	T23F6.2	T23F6.2	n/a	chrIV 12,722,330
13	smf-2	K11G12.3	n/a	chrX 6,717,366	C. elegans SMF-2 protein; contains similarity to Pfam domain PF01566 Natural resistance-associated macrophage protein contains similarity to Interpro domain IPR001046 (Natural resistance-associated macrophage protein)
14	srh-269	T03E6.5	n/a	chrV 16,591,043	C. elegans SRH-269 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	F52E1.9	F52E1.9	n/a	chrV 8,398,736	contains similarity to Interpro domain IPR011332 (Ribosomal protein, zinc-binding)
16	Y45F3A.5	Y45F3A.5	n/a	chrIII 10,585,998	contains similarity to Saccharomyces cerevisiae Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; SGD:YOR310C
17	F09D1.1	F09D1.1	n/a	chrII 2,570,590	contains similarity to Pfam domains PF00443 (Ubiquitin carboxyl-terminal hydrolase) , PF02148 (Zn-finger in ubiquitin-hydrolases and other protein) contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR001607 (Zinc finger, UBP-type)
18	C11D2.2	C11D2.2	n/a	chrIV 6,187,162	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001461 (Peptidase A1)
19	F38A1.13	F38A1.13	n/a	chrIV 1,265,538
20	gpa-4	T07A9.7	n/a	chrIV 403,531	gpa-4 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASI.
21	sre-52	C50E10.5	n/a	chrII 12,336,826	C. elegans SRE-52 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR005410 (Potassium channel, two pore-domain, THIK), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
22	K02D7.2	K02D7.2	n/a	chrIV 312,624	K02D7.2 encodes an ortholog of human SNAI2/SLUG (OMIM:602150, mutated in Waardenburg syndrome type IID) and Drosophila ESCARGOT; based on its orthology to SNAI2, K02D7.2 is predicted to be a transcriptional inhibitor.
23	K02D3.2	K02D3.2	n/a	chrX 13,710,264	contains similarity to Pfam domain PF01852 START domain contains similarity to Interpro domain IPR002913 (Lipid-binding START)
24	cdk-2	K03E5.3	n/a	chrI 3,411,552	C. elegans CDK-2 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
25	W02B8.1	W02B8.1	n/a	chrII 13,900,226
26	VW02B12L.2	VW02B12L.2	n/a	chrII 11,439,443	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
27	K09A11.5	K09A11.5	n/a	chrX 13,277,067	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
28	K10D2.4	K10D2.4	n/a	chrIII 5,173,569
29	nhr-100	C28D4.1	n/a	chrIV 9,729,825	nhr-100 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
30	srh-136	F36D3.6	n/a	chrV 16,496,767	C. elegans SRH-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	srv-8	F53F1.7	n/a	chrV 13,419,959	C. elegans SRV-8 protein; contains similarity to Interpro domains IPR002456 (GPCR, family 3, gamma-aminobutyric acid receptor, type B1), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)
32	grd-11	K02E2.2	n/a	chrV 20,356,705	grd-11 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, four Ground domains, an short region of low-complexity sequence, and a Hint/Hog domain; the Hint/Hog domain is predicted to cut GRD-2 into two halves and then covalently link cholesterol to the C-terminus of the Ground domain; the four N-terminal Ground domains are predicted to form one or more cysteine-crosslinked proteins involved in intercellular signalling; Ground domains have subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; grd-11 has no obvious function in RNAi assays.
33	C09G9.3	C09G9.3	n/a	chrIV 8,871,534	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
34	R07C12.2	R07C12.2	n/a	chrIV 4,149,092
35	cdh-4	F25F2.2	n/a	chrIII 4,528,691	A homolog of a member of the cadherin superfamily that is involved in cell-cell adhesion.
36	F31F7.2	F31F7.2	n/a	chrV 6,272,906	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)
37	F38B6.6	F38B6.6	n/a	chrX 6,687,229	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) (4), PF08409 (Domain of unknown function (DUF1736)) , PF00515 (Tetratricopeptide repeat) (5)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013618 (Region of unknown function DUF1736), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
38	cah-2	D1022.8	n/a	chrII 7,481,896	cah-2 encodes a predicted carbonic anhydrase.
39	fbxa-10	T12B5.3	n/a	chrIII 953,160	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
40	B0391.3	B0391.3	n/a	chrV 15,616,248	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000802 (Arsenical pump membrane protein)
41	F52D1.2	F52D1.2	n/a	chrX 447,631
42	srj-40	F38H12.2	n/a	chrV 4,102,865	C. elegans SRJ-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	C05B5.4	C05B5.4	n/a	chrIII 9,994,892	contains similarity to Mus musculus Soluble guanylyl cyclase beta 2 subunit homolog.; TR:Q8BXH3
44	C32A3.2	C32A3.2	n/a	chrIII 3,629,439	contains similarity to Homo sapiens Kinesin-like protein KIF14; ENSEMBL:ENSP00000236917
45	F29A7.5	F29A7.5	n/a	chrII 2,747,560
46	lis-1	T03F6.5	n/a	chrIII 13,373,822	lis-1 encodes an ortholog of human LIS1, which when mutated leads to lissencephaly (OMIM:247200); it also encodes an ortholog of the Aspergillus nidulans nudF, which mediates nuclear migration along Aspergillus hyphae.
47	ces-1	F43G9.11	n/a	chrI 8,634,989	ces-1 encodes a C2H2-type zinc finger transcription factor that is a member of the Snail family of proteins that includes Drosophila Scratch, Snail, and Slug, and human SNAIL and SLUG; although the normal function of CES-1 is not fully understood, gain-of-function mutations indicate that CES-1 can function as a transcriptional repressor that blocks programmed cell death in specific neurons by inhibiting expression of the cell-death activator EGL-1; in regulating EGL-1 expression, CES-1 appears to antagonize the transcriptional activity of the bHLH proteins, HLH-2 and HLH-3; despite its cell-type specific role in apoptosis, CES-1 expression is reportedly detected in many embryonic nuclei from the 100-cell stage of embryogenesis through the beginning of morphogenesis, with some CES-1 expression remaining at later embryonic stages; genetic studies indicate that CES-1 is negatively regulated by the bZIP transcription factor CES-2, which can bind CES-1 upstream sequences in vitro and thus may directly regulate CES-1 transcription in vivo
48	tbx-31	C36C9.2	n/a	chrX 1,672,652	tbx-31 encodes a diverged member of the T-box transcription factor family; by homology, TBX-31 is predicted to function as a transcriptional regulator during development, but as loss of tbx-31 activity via RNAi results in no obvious defects, the precise role of TBX-31 in C. elegans development and/or behavior is not yet known.
49	tor-2	Y37A1B.13	n/a	chrIV 13,983,393	tor-2 encodes a AAA ATPase that, along with TOR-1 and OOC-5, comprise the three C. elegans orthologs of human torsinA, mutations in which are associated with torsion dystonia (OMIM:605204); overexpression of TOR-2 in nematodes with polyglutamine repeat-induced protein aggregates indicates that TOR-2 can suppress protein aggregation, suggesting TOR-2 may play a role in regulation of protein folding; in wild-type animals, TOR-2 localizes to the endoplasmic reticulum; in animals containing polyglutamine protein aggregates, TOR-2 localizes to these sites of protein aggregation.
50	str-240	K02H11.2	n/a	chrV 1,521,205	C. elegans STR-240 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)