UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	B0524.5	B0524.5	3e-66	chrIII 1,892,549	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
2	sre-54	C50E10.6	n/a	chrII 12,333,899	C. elegans SRE-54 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
3	ZC15.1	ZC15.1	n/a	chrV 20,302,899	contains similarity to Interpro domains IPR001878 (Zn-finger, CCHC type), IPR000345 (Cytochrome c heme-binding site)
4	unc-46	C04F5.3	n/a	chrV 5,098,120	unc-46 encodes a novel protein with a single predicted transmembrane domain; UNC-46 and UNC-47, a novel transmembrane vesicular GABA transporter, are required in GABAergic neurons for all GABA neurotransmission, specifically for loading of GABA into synaptic vesicles, where UNC-46 is localized; UNC-46 localization requires UNC-47, which when overexpressed can rescue unc-46 mutant animals.
5	F35B3.3	F35B3.3	n/a	chrX 17,013,662
6	K03B4.4	K03B4.4	n/a	chrV 4,684,430	contains similarity to Interpro domain IPR002411 (Cereal allergen/alpha-amylase inhibitor, rice-type)
7	str-47	F07C4.1	n/a	chrV 7,646,392	C. elegans STR-47 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	grl-8	ZC487.5	n/a	chrV 6,732,495	grl-8 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
9	srj-15	Y40B10B.2	n/a	chrV 1,963,860	C. elegans SRJ-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002120 (Thyrotrophin-releasing hormone receptor)
10	F33D11.6	F33D11.6	n/a	chrI 5,845,654
11	clec-211	F19F10.6	n/a	chrV 7,560,915	C. elegans CLEC-211 protein; contains similarity to Interpro domain IPR016187 (C-type lectin fold)
12	F09F7.1	F09F7.1	n/a	chrIII 5,575,295
13	rcn-1	F54E7.7	n/a	chrIII 5,683,173	rcn-1 encodes a calcipressin, which binds and inhibits calcineurin; RCN-1's orthologs include yeast Rcn1p and human DSCR1 (OMIM:602917; overexpressed in Down syndrome and Alzheimer disease); rcn-1 is expressed in hypodermal seam cells, various neurons, vulval epithelial and muscle cells, marginal pharyngeal cells, and in the male tail; rcn-1 transcription is regulated by TAX-6, and RCN-1 binds TAX-6 protein if free Ca[2+] is present; RCN-1 overexpression, like calcineurin deficiency, causes defects in body size, cuticle thickness, fertility, growth rate, and serotonin-resistance in egg-laying.
14	clec-45	F07C4.2	n/a	chrV 7,638,344	C. elegans CLEC-45 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
15	F02C12.2	F02C12.2	n/a	chrX 13,398,638	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
16	C11E4.4	C11E4.4	n/a	chrX 9,594,806	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
17	F35D2.4	F35D2.4	n/a	chrII 7,581,981	contains similarity to Interpro domain IPR009030 (Growth factor, receptor)
18	fip-3	C06E1.5	n/a	chrIII 8,589,320	C. elegans FIP-3 protein ;
19	F11A5.13	F11A5.13	n/a	chrV 16,226,353	contains similarity to Clostridium acetobutylicum MDR-type permease.; TR:Q97D15
20	des-2	T26H10.1	n/a	chrV 11,417,794	des-2 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating the fast action of acetylcholine at neuromuscular junctions and in the nervous system; DES-2 is coexpressed with and genetically interacts with DEG-3, which which it probably forms heteromultimers, and DES-2 falls into the 'DEG-3' class of nAChR subunits, probably unique to nematodes, which includes DEG-3, ACR-5, ACR-17, ACR-18 ACR-20, and ACR-23.
21	C49C3.15	C49C3.15	n/a	chrIV 17,334,573	contains similarity to Interpro domain IPR002101 (Myristoylated alanine-rich C-kinase substrate MARCKS)
22	kin-23	W04G5.6	n/a	chrI 11,641,436	kin-23 encodes a predicted protein tyrosine kinase; like KIN-30, KIN-23 contains an unusual K to R substitution in kinase subdomain VII; kin-23 mRNA is expressed strongly during the L1/L2 larval stages, weakly in L3 and L4 stages, and at undetectable levels in adults.
23	Y32B12A.1	Y32B12A.1	n/a	chrV 16,488,780	contains similarity to Pfam domain PF00569 Zinc finger, ZZ type contains similarity to Interpro domain IPR000433 (Zinc finger, ZZ-type)
24	C31A11.1	C31A11.1	n/a	chrV 16,294,149	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
25	lpr-2	T12A7.5	n/a	chrIV 11,783,102	C. elegans LPR-2 protein; contains similarity to Interpro domains IPR012674 (Calycin), IPR011038 (Calycin-like), IPR002345 (Lipocalin)
26	srab-12	C47A10.6	n/a	chrV 17,782,010	C. elegans SRAB-12 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
27	F21D12.5	F21D12.5	n/a	chrII 7,329,535	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
28	ubc-22	C06E2.7	n/a	chrX 8,868,414	ubc-22 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae UBC8 and human UBC1/HIP2 (Huntingtin interacting protein 2, OMIM:602846) which are involved in regulating fructose-1,6-bisphosphatase and huntingtin catabolism, respectively; by homology, UBC-22 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-22 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-22 in C. elegans development and/or behavior is not yet known.
29	nhr-282	F54B8.2	n/a	chrV 15,812,667	C. elegans NHR-282 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	acr-15	F25G6.4	n/a	chrV 8,554,009	A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
31	C24D10.8	C24D10.8	n/a	chrIV 5,165,608	n/a
32	R160.5	R160.5	n/a	chrX 4,370,650
33	npr-9	ZK455.3	n/a	chrX 11,330,259	C. elegans NPR-9 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002286 (P2 purinoceptor), IPR001556 (Bombesin receptor), IPR009144 (Thyrotropin-releasing hormone receptor), IPR000586 (Somatostatin receptor), IPR000405 (Galanin receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
34	Y54E5A.2	Y54E5A.2	n/a	chrI 14,694,856	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
35	F54D12.8	F54D12.8	n/a	chrII 1,396,527	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR003609 (Apple-like)
36	T22H2.2	T22H2.2	n/a	chrI 11,705,155	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
37	F53B1.3	F53B1.3	n/a	chrX 2,106,394
38	acl-12	C01C10.3	n/a	chrX 7,440,941	C. elegans ACL-12 protein; contains similarity to Interpro domain IPR002123 (Phospholipid/glycerol acyltransferase)
39	str-115	F07B10.3	n/a	chrV 11,269,735	C. elegans STR-115 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	cyp-34A3	C41G6.1	n/a	chrV 15,229,059	C. elegans CYP-34A3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
41	F35C12.1	F35C12.1	n/a	chrI 9,805,249	contains similarity to Ralstonia solanacearum PopB.; TR:Q84IE7
42	str-3	M7.13	n/a	chrIV 11,099,437	str-3 encodes a seven transmembrane chemosensory receptor; STR-3 is expressed in the ASI chemosensory neurons; STR-3 expression in ASI is repressed in the presence of dauer pheromone at concentrations lower than that which induces dauer formation.
43	srt-35	F47D2.4	n/a	chrV 4,263,036	C. elegans SRT-35 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR001991 (Sodium:dicarboxylate symporter)
44	F27C1.10	F27C1.10	n/a	chrI 5,435,347
45	F14D7.5	F14D7.5	n/a	chrV 14,299,389	contains similarity to Bacteroides thetaiotaomicron Hypothetical protein.; TR:Q8ABS0
46	srv-10	F53F1.9	n/a	chrV 13,424,568	C. elegans SRV-10 protein; contains similarity to Interpro domain IPR001411 (Tetracycline resistance protein, TetB)
47	ZC487.2	ZC487.2	n/a	chrV 6,721,684
48	F11D5.6	F11D5.6	n/a	chrX 3,325,709
49	F19G12.1	F19G12.1	n/a	chrX 1,431,242	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
50	C01G5.4	C01G5.4	n/a	chrIV 6,533,692	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR003125 (Protein of unknown function WSN), IPR001399 (VP6 blue-tongue virus inner capsid protein)