UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	B0511.5	B0511.5	1e-158	chrI 10,630,197	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
2	apx-1	K08D9.3	n/a	chrV 3,216,670	apx-1 encodes one of ten C. elegans DSL (Delta, Serrate, LAG-2) proteins, integral transmembrane and secreted proteins that function as signaling ligands for the Notch family receptors GLP-1 and LIN-12; in the 4-cell embryo, maternally supplied APX-1 functions as a GLP-1 ligand for an inductive interaction that specifies the fate of the ABp blastomere; later in embryogenesis, APX-1 is required for formation of the LIN-12-dependent, invariant asymmetrical twist that occurs as part of normal gut morphogenesis; during larval development, APX-1 is required redundantly with DSL-1 and LAG-2 for the LIN-12-mediated lateral signal that spatially patterns the primary and secondary vulval cell lineages; in the early embryo, APX-1 is first detected at the anterior edge of the P1 blastomere, with later expression visible in P2 at sites of contact with ABp, and in the cytoplasm of the EMS and P3 blastomeres; expression in the vulval precursor cells (VPCs) is detected in the primary VPC, P6.p, and its descendants; embryonic APX-1 expression is dependent upon PIE-1 activity, while later vulval expression is mediated by the Ras signaling pathway and the SUR-2 transcriptional cofactor.
3	F09E10.6	F09E10.6	n/a	chrX 1,496,339
4	fbxa-45	F09C6.6	n/a	chrV 16,898,926	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
5	Y116A8C.9	Y116A8C.9	n/a	chrIV 16,943,608	contains similarity to Danio rerio Transmembrane protein 185-like.; SW:Q7SYC7
6	C03B1.9	C03B1.9	n/a	chrX 6,346,694
7	srg-59	C24B9.7	n/a	chrV 2,724,113	C. elegans SRG-59 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
8	immp-1	C24H11.6	n/a	chrIII 11,775,731	C. elegans IMMP-1 protein; contains similarity to Pfam domain PF00717 Peptidase S24-like contains similarity to Interpro domains IPR001733 (Peptidase S26B, eukaryotic signal peptidase), IPR015927 (Peptidase S24, S26A, S26B and S26C), IPR014037 (Peptidase S26A), IPR011056 (Peptidase S24, S26A and S26B, C-terminal), IPR000223 (Peptidase S26A, signal peptidase I)
9	C52D10.3	C52D10.3	n/a	chrIV 17,179,526	contains similarity to Pelobacter propionicus DSM 2379 Hypothetical protein precursor.; TR:Q3FZT0
10	E04A4.6	E04A4.6	n/a	chrIV 4,746,804	contains similarity to Homo sapiens Isoform 5 of Tectonic-1 precursor; ENSEMBL:ENSP00000380771
11	R12B2.3	R12B2.3	n/a	chrIII 5,806,220
12	srh-77	DC2.6	n/a	chrV 224,988	C. elegans SRH-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	R53.2	R53.2	n/a	chrII 9,964,971	contains similarity to Pfam domain PF02223 Thymidylate kinase contains similarity to Interpro domain IPR000062 (Thymidylate kinase)
14	srd-44	F17A2.8	n/a	chrX 12,339,267	C. elegans SRD-44 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	ptr-13	K07C10.1	n/a	chrII 11,159,735	ptr-13 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-13 is weakly required for normal molting from L4 to adult stages; PTR-13 is also required for normal growth to full size and locomotion.
16	C50F2.4	C50F2.4	n/a	chrI 3,890,325
17	R07E5.11	R07E5.11	n/a	chrIII 4,415,004	contains similarity to Salmonella typhimurium Putative surface-exposed virulence protein bigA precursor.; SW:BIGA_SALTY
18	M153.3	M153.3	n/a	chrX 12,143,295	contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
19	Y79H2A.4	Y79H2A.4	n/a	chrIII 12,041,576	contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
20	K08D10.11	K08D10.11	n/a	chrIV 4,185,528
21	srm-3	F58G6.2	n/a	chrIV 9,649,830	C. elegans SRM-3 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	T02G5.11	T02G5.11	n/a	chrII 7,080,284	contains similarity to Pfam domain PF05741 Nanos RNA binding domain contains similarity to Interpro domain IPR008705 (Zinc finger, Nanos)
23	F55F8.3	F55F8.3	n/a	chrI 5,651,700	contains similarity to Pfam domains PF04047 (Periodic tryptophan protein 2 WD repeat associated presumed domain) , PF00400 (WD domain, G-beta repeat) (5)contains similarity to Interpro domains IPR000009 (Protein phosphatase 2A, regulatory subunit PR55), IPR017441 (Protein kinase ATP binding, conserved site), IPR011046 (WD40 repeat-like), IPR007190 (Periodic tryptophan protein-associated region), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
24	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
25	W06G6.9	W06G6.9	n/a	chrV 16,646,169	contains similarity to Ralstonia solanacearum Hypothetical protein RSc2317.; TR:Q8XX01
26	clec-90	F57C9.2	n/a	chrI 4,846,413	C. elegans CLEC-90 protein; contains similarity to Interpro domains IPR002919 (Protease inhibitor I8, cysteine-rich trypsin inhibitor-like), IPR001304 (C-type lectin)
27	athp-1	C44B9.4	n/a	chrIII 10,887,899	C. elegans ATHP-1 protein; contains similarity to Pfam domains PF02178 (AT hook motif) (2), PF00628 (PHD-finger) contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000294 (Vitamin K-dependent carboxylation/gamma-carboxyglutamic region), IPR000253 (Forkhead-associated), IPR011011 (Zinc finger, FYVE/PHD-type)
28	W04C9.6	W04C9.6	n/a	chrI 485,237	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
29	nhr-181	F38H12.3	n/a	chrV 4,097,665	nhr-181 encodes a putative nuclear hormone receptor (NHR), belonging to a large nematode-specific expanded family of NHRs, that inhibits CEP-1- and HUS-1-dependent germline apoptosis as do BMK-1, RAD-50, and RAD-51.
30	K09H11.5	K09H11.5	n/a	chrV 5,728,063
31	srh-233	Y113G7A.1	n/a	chrV 20,046,361	C. elegans SRH-233 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	Y38H6C.8	Y38H6C.8	n/a	chrV 20,510,594	contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR002350 (Proteinase inhibitor I1, Kazal), IPR003990 (Pancreatitis-associated protein), IPR002352 (Eosinophil major basic protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	F28B1.5	F28B1.5	n/a	chrV 17,058,496
34	M03E7.2	M03E7.2	n/a	chrV 5,617,970	contains similarity to Plasmodium berghei 58 kDa phosphoprotein (Heat shock-related protein) (HRP).; SW:Q08168
35	str-122	W03D2.10	n/a	chrIV 4,067,151	C. elegans STR-122 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	T08G5.7	T08G5.7	n/a	chrV 14,044,675	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
37	C02H6.1	C02H6.1	n/a	chrV 7,389,111	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
38	F35F10.14	F35F10.14	n/a	chrV 3,319,580
39	F20H11.6	F20H11.6	n/a	chrIII 6,599,869
40	C28G1.4	C28G1.4	n/a	chrX 8,851,319	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
41	ZK1098.5	ZK1098.5	n/a	chrIII 9,526,211	ZK1098.5 encodes a unfamiliar protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
42	tmbi-4	B0563.4	n/a	chrX 9,155,606	C. elegans TMBI-4 protein; contains similarity to Pfam domain PF01027 Uncharacterised protein family UPF0005 contains similarity to Interpro domain IPR006214 (Protein of unknown function UPF0005)
43	srd-46	F17A2.10	n/a	chrX 12,332,621	C. elegans SRD-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	srsx-27	C51E3.2	n/a	chrV 10,151,415	C. elegans SRSX-27 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
45	grl-1	C24G6.7	n/a	chrV 5,532,342	grl-1 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; GRL-1 is expressed in intestine, neurons, and larval arcade cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
46	R10D12.7	R10D12.7	n/a	chrV 13,950,209	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
47	F48C1.3	F48C1.3	n/a	chrI 5,314,472
48	zyg-8	Y79H2A.11	n/a	chrIII 12,066,888	The zyg-8 gene encodes a protein with a doublecortin-like domain and a protein kinase domain; mutations of zyg-8 impair mitosis at the one-cell embryonic stage, which is normally asymmetrical, but which fails to show proper asymmetry in zyg-8 mutant embryos.
49	sptf-3	Y40B1A.4	n/a	chrI 13,362,400	C. elegans SPTF-3 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
50	srd-41	F17A2.6	n/a	chrX 12,327,467	C. elegans SRD-41 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site)