UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	B0412.3	B0412.3	0	chrIII 802,243	contains similarity to Pfam domain PF07919 Protein of unknown function (DUF1683) contains similarity to Interpro domain IPR012880 (Protein of unknown function DUF1683, C-terminal)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	pgp-7	T21E8.2	n/a	chrX 10,867,530	pgp-7 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-7 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-7 activity via RNAi results in no obvious defects, the precise role of PGP-7 in C. elegans development and/or behavior is not yet known; pgp-7 promoter-gfp fusion proteins are expressed in the rays of the adult male tail.
4	his-31	F17E9.12	n/a	chrIV 8,333,809	his-31 encodes an H4 histone; his-31 is contained within the histone gene cluster HIS5.
5	srt-1	C13B7.1	n/a	chrV 2,436,754	C. elegans SRT-1 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
6	C15B12.6	C15B12.6	n/a	chrX 6,498,835
7	srh-131	Y102A5C.31	n/a	chrV 17,006,090	C. elegans SRH-131 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	egg-4	T21E3.1	n/a	chrI 3,933,502	C. elegans EGG-4 protein; contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
9	ubc-12	R09B3.4	n/a	chrI 11,911,676	The ubc-12 gene encodes a ubiquitin-conjugating enzyme whose substrate is NED-8, and which is required for both embryogenesis and terminal hypodermal differentiation; ubc-12(RNAi) mutants either arrest during embryonic development or show pleotropic defects (e.g., vulval eversion during the L4 stage), as well as defective alae.
10	W07E6.3	W07E6.3	n/a	chrII 496,617	contains similarity to Interpro domain IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase)
11	F42A6.1	F42A6.1	n/a	chrIV 3,356,300
12	srz-90	C18D4.9	n/a	chrV 17,528,936	C. elegans SRZ-90 protein
13	W10G6.1	W10G6.1	n/a	chrX 16,245,293	contains similarity to Babesia bovis Merozoite surface antigen-2a2.; TR:Q95UH0
14	T07D3.3	T07D3.3	n/a	chrII 895,627	contains similarity to Homo sapiens CGI16-iso; ENSEMBL:ENSP00000368599
15	grl-21	ZC168.5	n/a	chrIV 10,737,774	grl-21 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-21 is expressed in arcade cells and hypodermis; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
16	str-20	C05E4.2	n/a	chrV 757,182	C. elegans STR-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	tag-179	T24D1.4	n/a	chrI 9,961,143	C. elegans TAG-179 protein; contains similarity to Pfam domain PF04922 DIE2/ALG10 family contains similarity to Interpro domains IPR016900 (Alpha-1, 2 glucosyltransferase Alg10), IPR007006 (DIE2/ALG10)
18	glb-18	F52A8.4	n/a	chrI 7,344,423	glb-18 encodes a globin; glb-18 is expressed in larval and adult neurons and excretory gland cells, and in adult spermetheca and vulva; glb-18 transcription is higher in L3 and dauers than in young adults; glb-18 has no obvious function in mass RNAi assays.
19	C27B7.2	C27B7.2	n/a	chrIV 8,893,280	contains similarity to Arabidopsis thaliana F3O9.12 protein (At1g16320/F3O9_12).; TR:Q9SA31
20	btb-5	W05G11.5	n/a	chrIII 60,257	C. elegans BTB-5 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
21	nhr-76	C05G6.1	n/a	chrIV 630,739	C. elegans NHR-76 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
22	Y57G11A.4	Y57G11A.4	n/a	chrIV 14,484,352	contains similarity to Interpro domain IPR005018 (DOMON related)
23	T03G6.3	T03G6.3	n/a	chrX 2,613,474	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017850 (Alkaline-phosphatase-like, core domain)
24	C23H5.1	C23H5.1	n/a	chrIV 2,132,010	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
25	Y6B3B.4	Y6B3B.4	n/a	chrI 13,765,684	contains similarity to Interpro domain IPR000533 (Tropomyosin)
26	frk-1	T04B2.2	n/a	chrIV 10,044,780	frk-1 encodes a non-receptor tyrosine kinase orthologous to the human proto-oncogene Fer; frk-1 is an essential gene required early for embryonic cell proliferation and later in embryonic epidermal cells for enclosure, morphogenesis and late stages of differentiation; FRK-1's role in embryonic development is independent of its kinase domain, and when expressed in cultured mammalian cells, FRK-1 disrupts cell adhesion; FRK-1 is initially expressed in all cells of the early embryo where it localizes to nuclei and points of cell-cell contact; later expression is seen in epithelial cells, body wall muscle, and the adult germline, including mature sperm; FRK-1 expression in epidermal cells requires activity of the ELT-1 GATA transcription factor, and FRK-1 localization to the plasma membrane requires PAT-3/Beta-integrin, JAC-1/p120 catenin, and HMP-2/Beta-catenin with which FRK-1 interacts in vitro.
27	F47G9.4	F47G9.4	n/a	chrV 11,319,469	contains similarity to Pfam domain PF00643 B-box zinc finger contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
28	M02F4.1	M02F4.1	n/a	chrX 3,028,999	contains similarity to Homo sapiens Isoform 1 of Splicing factor, arginine/serine-rich 12; ENSEMBL:ENSP00000284041
29	nhr-254	ZK6.5	n/a	chrV 393,883	C. elegans NHR-254 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	F39F10.2	F39F10.2	n/a	chrX 16,895,317	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
31	Y116A8C.22	Y116A8C.22	n/a	chrIV 17,047,371	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
32	F25B4.7	F25B4.7	n/a	chrV 5,686,614	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
33	ptc-2	F21H12.4	n/a	chrII 6,084,701	ptc-2 encodes an ortholog of Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome), which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTC-2 is required for normal fat storage; PTC-2 is also required for normal egg osmotic integrity, locomotion, egg laying, and viability in mass RNAi assays.
34	Y17G7B.3	Y17G7B.3	n/a	chrII 11,990,838	Y17G7B.3 is orthologous to the human gene HYDROXYACYLGLUTATHIONE HYDROLASE (HAGH; OMIM:138760), which when mutated leads to disease.
35	clec-218	W02D7.2	n/a	chrV 8,309,344	C. elegans CLEC-218 protein; contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
36	Y43F8B.11	Y43F8B.11	n/a	chrV 19,471,547	contains similarity to Campylobacter coli CadF precursor (Outer membrane protein).; TR:O06895
37	W02A11.1	W02A11.1	n/a	chrI 12,731,353	contains similarity to Pfam domain PF08704 tRNA methyltransferase complex GCD14 subunit contains similarity to Interpro domain IPR014816 (tRNA methyltransferase complex GCD14 subunit)
38	srw-83	ZK262.6	n/a	chrV 18,428,523	C. elegans SRW-83 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
39	Y32B12B.1	Y32B12B.1	n/a	chrV 16,536,916	contains similarity to Leptospira kirschneri serovar grippotyphosa Hypothetical protein.; TR:Q8KWV2
40	T07D3.6	T07D3.6	n/a	chrII 881,565	contains similarity to Pfam domain PF06828 Fukutin-related contains similarity to Interpro domain IPR009644 (Fukutin-related)
41	B0432.6	B0432.6	n/a	chrII 267,814	contains similarity to Interpro domain IPR000533 (Tropomyosin)
42	M142.5	M142.5	n/a	chrIII 10,931,599	contains similarity to Homo sapiens Isoform 1 of Protein LSM12 homolog; ENSEMBL:ENSP00000293406
43	R11.3	R11.3	n/a	chrX 16,198,339	contains similarity to Haemophilus influenzae Hypothetical protein HI0386.; SW:YBGC_HAEIN
44	nhr-256	ZK697.2	n/a	chrV 1,745,848	C. elegans NHR-256 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
45	Y4C6B.6	Y4C6B.6	n/a	chrIV 5,347,749	The Y4C6B.6 gene encodes a homolog of the human gene GLCM, which when mutated leads to Gaucher disease type I (OMIM:230800).
46	srt-63	T28A11.15	n/a	chrV 3,255,375	C. elegans SRT-63 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	C29G2.3	C29G2.3	n/a	chrV 2,581,907
48	C50E3.2	C50E3.2	n/a	chrV 7,610,647	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
49	fbxb-76	H02I12.2	n/a	chrIV 11,378,732	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
50	fbxa-37	ZC47.14	n/a	chrIII 1,286,023	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.